1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone

C184H167F29N10O25 — CID 160705935

IUPAC1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone
SMILESCC(=O)c1cc(-c2ccc(F)cc2)c2c(n1)O[C@H](COC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)OC(C)(C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H](C(C)C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H](C1CC1)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H](COC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H]([C@@H](C)OC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H]([C@H](C)OC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@H](C(C)C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@H](C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@H](COC(F)F)CC2
InChIInChI=1S/2C19H17F4NO3.C19H17F2NO2.2C19H19F2NO2.2C18H15F4NO3.C18H16F3NO3.C18H17F2NO2.C17H15F2NO2/c2*1-9(25)16-8-14(12-4-3-11(20)7-15(12)21)13-5-6-17(27-18(13)24-16)10(2)26-19(22)23;1-10(23)17-9-15(13-5-4-12(20)8-16(13)21)14-6-7-18(11-2-3-11)24-19(14)22-17;2*1-10(2)18-7-6-14-15(13-5-4-12(20)8-16(13)21)9-17(11(3)23)22-19(14)24-18;2*1-9(24)16-7-14(12-4-2-10(19)6-15(12)20)13-5-3-11(8-25-18(21)22)26-17(13)23-16;1-10(23)16-8-15(11-2-4-12(19)5-3-11)14-7-6-13(9-24-18(20)21)25-17(14)22-16;1-10(22)16-9-14(12-5-4-11(19)8-15(12)20)13-6-7-18(2,3)23-17(13)21-16;1-9-3-5-13-14(12-6-4-11(18)7-15(12)19)8-16(10(2)21)20-17(13)22-9/h2*3-4,7-8,10,17,19H,5-6H2,1-2H3;4-5,8-9,11,18H,2-3,6-7H2,1H3;2*4-5,8-10,18H,6-7H2,1-3H3;2*2,4,6-7,11,18H,3,5,8H2,1H3;2-5,8,13,18H,6-7,9H2,1H3;4-5,8-9H,6-7H2,1-3H3;4,6-9H,3,5H2,1-2H3/t10-,17+;10-,17-;3*18-;2*11-;13-;;9-/m01110100.1/s1
InChIKeyRRFOWTKQTSFRAM-NANOTGLBSA-N
MW3469.35 g/mol
LogP43.22
Rot. Bonds38

About 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone

1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone (PubChem CID 160705935) has the molecular formula C184H167F29N10O25 and a molecular weight of 3469.35 g/mol. Its IUPAC name is 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone.

Molecular Properties

Compound Name1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone
PubChem CID160705935
Molecular FormulaC184H167F29N10O25
Molecular Weight3469.35 g/mol
Exact Mass3467.16
IUPAC Name1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone
SMILESCC(=O)c1cc(-c2ccc(F)cc2)c2c(n1)O[C@H](COC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)OC(C)(C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H](C(C)C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H](C1CC1)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H](COC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H]([C@@H](C)OC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H]([C@H](C)OC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@H](C(C)C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@H](C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@H](COC(F)F)CC2
InChIInChI=1S/2C19H17F4NO3.C19H17F2NO2.2C19H19F2NO2.2C18H15F4NO3.C18H16F3NO3.C18H17F2NO2.C17H15F2NO2/c2*1-9(25)16-8-14(12-4-3-11(20)7-15(12)21)13-5-6-17(27-18(13)24-16)10(2)26-19(22)23;1-10(23)17-9-15(13-5-4-12(20)8-16(13)21)14-6-7-18(11-2-3-11)24-19(14)22-17;2*1-10(2)18-7-6-14-15(13-5-4-12(20)8-16(13)21)9-17(11(3)23)22-19(14)24-18;2*1-9(24)16-7-14(12-4-2-10(19)6-15(12)20)13-5-3-11(8-25-18(21)22)26-17(13)23-16;1-10(23)16-8-15(11-2-4-12(19)5-3-11)14-7-6-13(9-24-18(20)21)25-17(14)22-16;1-10(22)16-9-14(12-5-4-11(19)8-15(12)20)13-6-7-18(2,3)23-17(13)21-16;1-9-3-5-13-14(12-6-4-11(18)7-15(12)19)8-16(10(2)21)20-17(13)22-9/h2*3-4,7-8,10,17,19H,5-6H2,1-2H3;4-5,8-9,11,18H,2-3,6-7H2,1H3;2*4-5,8-10,18H,6-7H2,1-3H3;2*2,4,6-7,11,18H,3,5,8H2,1H3;2-5,8,13,18H,6-7,9H2,1H3;4-5,8-9H,6-7H2,1-3H3;4,6-9H,3,5H2,1-2H3/t10-,17+;10-,17-;3*18-;2*11-;13-;;9-/m01110100.1/s1
InChIKeyRRFOWTKQTSFRAM-NANOTGLBSA-N
XLogP43.22
TPSA438.05 Ų
H-Bond Donors
H-Bond Acceptors35
Rotatable Bonds38
Heavy Atoms248
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003469.35
LogP ≤ 543.22
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1035

Analyze 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone with MolForge

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Frequently Asked Questions

What is the IUPAC name of 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone?
The IUPAC name of 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone (CID 160705935) is 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone.
What is the SMILES notation for 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone?
The canonical SMILES for 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone is CC(=O)c1cc(-c2ccc(F)cc2)c2c(n1)O[C@H](COC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)OC(C)(C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H](C(C)C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H](C1CC1)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H](COC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H]([C@@H](C)OC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@@H]([C@H](C)OC(F)F)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@H](C(C)C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@H](C)CC2.CC(=O)c1cc(-c2ccc(F)cc2F)c2c(n1)O[C@H](COC(F)F)CC2.
What is the InChIKey of 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone?
The InChIKey is RRFOWTKQTSFRAM-NANOTGLBSA-N. The full InChI is InChI=1S/2C19H17F4NO3.C19H17F2NO2.2C19H19F2NO2.2C18H15F4NO3.C18H16F3NO3.C18H17F2NO2.C17H15F2NO2/c2*1-9(25)16-8-14(12-4-3-11(20)7-15(12)21)13-5-6-17(27-18(13)24-16)10(2)26-19(22)23;1-10(23)17-9-15(13-5-4-12(20)8-16(13)21)14-6-7-18(11-2-3-11)24-19(14)22-17;2*1-10(2)18-7-6-14-15(13-5-4-12(20)8-16(13)21)9-17(11(3)23)22-19(14)24-18;2*1-9(24)16-7-14(12-4-2-10(19)6-15(12)20)13-5-3-11(8-25-18(21)22)26-17(13)23-16;1-10(23)16-8-15(11-2-4-12(19)5-3-11)14-7-6-13(9-24-18(20)21)25-17(14)22-16;1-10(22)16-9-14(12-5-4-11(19)8-15(12)20)13-6-7-18(2,3)23-17(13)21-16;1-9-3-5-13-14(12-6-4-11(18)7-15(12)19)8-16(10(2)21)20-17(13)22-9/h2*3-4,7-8,10,17,19H,5-6H2,1-2H3;4-5,8-9,11,18H,2-3,6-7H2,1H3;2*4-5,8-10,18H,6-7H2,1-3H3;2*2,4,6-7,11,18H,3,5,8H2,1H3;2-5,8,13,18H,6-7,9H2,1H3;4-5,8-9H,6-7H2,1-3H3;4,6-9H,3,5H2,1-2H3/t10-,17+;10-,17-;3*18-;2*11-;13-;;9-/m01110100.1/s1.
What are the key properties of 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone?
1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone has a molecular weight of 3469.35 g/mol, XLogP of 43.22, 38 rotatable bonds, 0 hydrogen bond donors, and 35 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[(2R)-2-cyclopropyl-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1R)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-[(1S)-1-(difluoromethoxy)ethyl]-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-2-(difluoromethoxymethyl)-5-(2,4-difluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-2-(difluoromethoxymethyl)-5-(4-fluorophenyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[5-(2,4-difluorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-methyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2S)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone;1-[(2R)-5-(2,4-difluorophenyl)-2-propan-2-yl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-7-yl]ethanone is sourced from PubChem (CID 160705935), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).