1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one

C109H119ClF4N26O14 — CID 160721678

IUPAC1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one
SMILESC[C@@H]1CN(c2ncc(-c3nc4c(cc3F)c(=O)n(C)n4Cc3ccccc3OC(F)F)cn2)CCN1C(=O)CO.Cc1c(-c2cnc(N3CCN(C(=O)CO)[C@H](C)C3)nc2)ccc2c(=O)n(C)n(Cc3ccccc3Cl)c12.Cc1c(-c2cnc(N3CCN(C(=O)CO)[C@H](C)C3)nc2)ccc2c(=O)n(C)n(Cc3ccccc3OC(C)F)c12.Cc1ccnc(C(C)n2c3cc(-c4cnc(N5CCN(C(=O)CO)[C@H](C)C5)nc4)ccc3c(=O)n2C)c1
InChIInChI=1S/C29H33FN6O4.C27H29ClN6O3.C27H31N7O3.C26H26F3N7O4/c1-18-15-34(11-12-35(18)26(38)17-37)29-31-13-22(14-32-29)23-9-10-24-27(19(23)2)36(33(4)28(24)39)16-21-7-5-6-8-25(21)40-20(3)30;1-17-14-32(10-11-33(17)24(36)16-35)27-29-12-20(13-30-27)21-8-9-22-25(18(21)2)34(31(3)26(22)37)15-19-6-4-5-7-23(19)28;1-17-7-8-28-23(11-17)19(3)34-24-12-20(5-6-22(24)26(37)31(34)4)21-13-29-27(30-14-21)32-9-10-33(18(2)15-32)25(36)16-35;1-15-12-34(7-8-35(15)21(38)14-37)26-30-10-17(11-31-26)22-19(27)9-18-23(32-22)36(33(2)24(18)39)13-16-5-3-4-6-20(16)40-25(28)29/h5-10,13-14,18,20,37H,11-12,15-17H2,1-4H3;4-9,12-13,17,35H,10-11,14-16H2,1-3H3;5-8,11-14,18-19,35H,9-10,15-16H2,1-4H3;3-6,9-11,15,25,37H,7-8,12-14H2,1-2H3/t18-,20?;17-;18-,19?;15-/m1111/s1
InChIKeyRTEKQSDZRNPTJX-DXMJAYDWSA-N
MW2128.76 g/mol
LogP9.86
Rot. Bonds24

About 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one

1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one (PubChem CID 160721678) has the molecular formula C109H119ClF4N26O14 and a molecular weight of 2128.76 g/mol. Its IUPAC name is 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one.

Molecular Properties

Compound Name1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one
PubChem CID160721678
Molecular FormulaC109H119ClF4N26O14
Molecular Weight2128.76 g/mol
Exact Mass2126.90
IUPAC Name1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one
SMILESC[C@@H]1CN(c2ncc(-c3nc4c(cc3F)c(=O)n(C)n4Cc3ccccc3OC(F)F)cn2)CCN1C(=O)CO.Cc1c(-c2cnc(N3CCN(C(=O)CO)[C@H](C)C3)nc2)ccc2c(=O)n(C)n(Cc3ccccc3Cl)c12.Cc1c(-c2cnc(N3CCN(C(=O)CO)[C@H](C)C3)nc2)ccc2c(=O)n(C)n(Cc3ccccc3OC(C)F)c12.Cc1ccnc(C(C)n2c3cc(-c4cnc(N5CCN(C(=O)CO)[C@H](C)C5)nc4)ccc3c(=O)n2C)c1
InChIInChI=1S/C29H33FN6O4.C27H29ClN6O3.C27H31N7O3.C26H26F3N7O4/c1-18-15-34(11-12-35(18)26(38)17-37)29-31-13-22(14-32-29)23-9-10-24-27(19(23)2)36(33(4)28(24)39)16-21-7-5-6-8-25(21)40-20(3)30;1-17-14-32(10-11-33(17)24(36)16-35)27-29-12-20(13-30-27)21-8-9-22-25(18(21)2)34(31(3)26(22)37)15-19-6-4-5-7-23(19)28;1-17-7-8-28-23(11-17)19(3)34-24-12-20(5-6-22(24)26(37)31(34)4)21-13-29-27(30-14-21)32-9-10-33(18(2)15-32)25(36)16-35;1-15-12-34(7-8-35(15)21(38)14-37)26-30-10-17(11-31-26)22-19(27)9-18-23(32-22)36(33(2)24(18)39)13-16-5-3-4-6-20(16)40-25(28)29/h5-10,13-14,18,20,37H,11-12,15-17H2,1-4H3;4-9,12-13,17,35H,10-11,14-16H2,1-3H3;5-8,11-14,18-19,35H,9-10,15-16H2,1-4H3;3-6,9-11,15,25,37H,7-8,12-14H2,1-2H3/t18-,20?;17-;18-,19?;15-/m1111/s1
InChIKeyRTEKQSDZRNPTJX-DXMJAYDWSA-N
XLogP9.86
TPSA430.20 Ų
H-Bond Donors4
H-Bond Acceptors36
Rotatable Bonds24
Heavy Atoms154
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002128.76
LogP ≤ 59.86
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1036

Analyze 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one with MolForge

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Related Compounds

1-[[2-(difluoromethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylindazol-3-one
CID 122620386
1-[[2-(difluoromethoxy)phenyl]methyl]-5,7-difluoro-6-[2-[4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylindazol-3-one
CID 122620298
1-[[2-(difluoromethoxy)phenyl]methyl]-2-methyl-6-[2-[(3R)-3-methyl-4-[(2R)-2,4,4-trihydroxybutanoyl]piperazin-1-yl]pyrimidin-5-yl]indazol-3-one
CID 134382298
methyl 4-[5-[1-[[2-(difluoromethoxy)-5-methylphenyl]methyl]-2-methyl-3-oxoindazol-6-yl]pyrimidin-2-yl]-2-methylpiperazine-1-carboxylate
CID 122620416
methyl (2R)-4-[5-[1-[[2-(difluoromethoxy)-5-methylphenyl]methyl]-2-methyl-3-oxoindazol-6-yl]pyrimidin-2-yl]-2-methylpiperazine-1-carboxylate
CID 122620418
tert-butyl 4-[5-[1-[[2-(difluoromethoxy)-5-methylphenyl]methyl]-2-methyl-3-oxoindazol-6-yl]pyrimidin-2-yl]-2-methylpiperazine-1-carboxylate
CID 122620329
1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-2-methyl-6-[2-[(3R)-3-methylpiperazin-1-yl]pyrimidin-5-yl]indazol-3-one;[2-[(2R)-4-[5-[1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-2-methyl-3-oxoindazol-6-yl]pyrimidin-2-yl]-2-methylpiperazin-1-yl]-2-oxoethyl] acetate;dihydrochloride
CID 157059892
1-[[2-(difluoromethoxy)phenyl]methyl]-7-fluoro-6-[2-[(2R)-4-(2-hydroxyacetyl)-2-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylindazol-3-one
CID 122621565
1-[[2-(difluoromethoxy)-5-methylphenyl]methyl]-2-methyl-6-[2-[(3R)-3-methyl-4-(oxetane-2-carbonyl)piperazin-1-yl]pyrimidin-5-yl]indazol-3-one
CID 122620380
1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(2R)-4-(2-hydroxyacetyl)-2-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylindazol-3-one
CID 159432696
[2-[(2R)-4-[5-[1-[[2-(difluoromethoxy)phenyl]methyl]-2-methyl-3-oxoindazol-6-yl]pyrimidin-2-yl]-2-methylpiperazin-1-yl]-2-oxoethyl] 3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate
CID 122620922
1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-3-oxoindazole-7-carbonitrile;1-[(2-chlorophenyl)methyl]-2-methyl-6-[2-[(3R)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-3-oxoindazole-7-carbonitrile
CID 158500461

Frequently Asked Questions

What is the IUPAC name of 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one?
The IUPAC name of 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one (CID 160721678) is 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one.
What is the SMILES notation for 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one?
The canonical SMILES for 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one is C[C@@H]1CN(c2ncc(-c3nc4c(cc3F)c(=O)n(C)n4Cc3ccccc3OC(F)F)cn2)CCN1C(=O)CO.Cc1c(-c2cnc(N3CCN(C(=O)CO)[C@H](C)C3)nc2)ccc2c(=O)n(C)n(Cc3ccccc3Cl)c12.Cc1c(-c2cnc(N3CCN(C(=O)CO)[C@H](C)C3)nc2)ccc2c(=O)n(C)n(Cc3ccccc3OC(C)F)c12.Cc1ccnc(C(C)n2c3cc(-c4cnc(N5CCN(C(=O)CO)[C@H](C)C5)nc4)ccc3c(=O)n2C)c1.
What is the InChIKey of 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one?
The InChIKey is RTEKQSDZRNPTJX-DXMJAYDWSA-N. The full InChI is InChI=1S/C29H33FN6O4.C27H29ClN6O3.C27H31N7O3.C26H26F3N7O4/c1-18-15-34(11-12-35(18)26(38)17-37)29-31-13-22(14-32-29)23-9-10-24-27(19(23)2)36(33(4)28(24)39)16-21-7-5-6-8-25(21)40-20(3)30;1-17-14-32(10-11-33(17)24(36)16-35)27-29-12-20(13-30-27)21-8-9-22-25(18(21)2)34(31(3)26(22)37)15-19-6-4-5-7-23(19)28;1-17-7-8-28-23(11-17)19(3)34-24-12-20(5-6-22(24)26(37)31(34)4)21-13-29-27(30-14-21)32-9-10-33(18(2)15-32)25(36)16-35;1-15-12-34(7-8-35(15)21(38)14-37)26-30-10-17(11-31-26)22-19(27)9-18-23(32-22)36(33(2)24(18)39)13-16-5-3-4-6-20(16)40-25(28)29/h5-10,13-14,18,20,37H,11-12,15-17H2,1-4H3;4-9,12-13,17,35H,10-11,14-16H2,1-3H3;5-8,11-14,18-19,35H,9-10,15-16H2,1-4H3;3-6,9-11,15,25,37H,7-8,12-14H2,1-2H3/t18-,20?;17-;18-,19?;15-/m1111/s1.
What are the key properties of 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one?
1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one has a molecular weight of 2128.76 g/mol, XLogP of 9.86, 24 rotatable bonds, 4 hydrogen bond donors, and 36 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[(2-chlorophenyl)methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;1-[[2-(difluoromethoxy)phenyl]methyl]-5-fluoro-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methylpyrazolo[3,4-b]pyridin-3-one;1-[[2-(1-fluoroethoxy)phenyl]methyl]-6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2,7-dimethylindazol-3-one;6-[2-[(3R)-4-(2-hydroxyacetyl)-3-methylpiperazin-1-yl]pyrimidin-5-yl]-2-methyl-1-[1-(4-methyl-2-pyridinyl)ethyl]indazol-3-one is sourced from PubChem (CID 160721678), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).