7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide

C120H101F5N16O14 — CID 160725628

About 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide

7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide (PubChem CID 160725628) has the molecular formula C120H101F5N16O14 and a molecular weight of 2086.22 g/mol. Its IUPAC name is 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide.

Molecular Properties

• Compound Name: 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide
• PubChem CID: 160725628
• Molecular Formula: C120H101F5N16O14
• Molecular Weight: 2086.22 g/mol
• Exact Mass: 2084.76
• IUPAC Name: 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide
• SMILES: CC1(C)CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C(=O)C1.CC1(c2ccccc2)CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1=O.CCC1(C)CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1=O.CN1C(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C(=O)C1(C)C.N#Cc1cc(-c2ccc(F)cc2)c2ccc(CN3C(=O)CCC3=O)cc2n1
• InChI: InChI=1S/C28H22FN3O3.2C24H22FN3O3.C23H21FN4O3.C21H14FN3O2/c1-28(19-5-3-2-4-6-19)15-25(33)32(27(28)35)16-17-7-12-21-22(18-8-10-20(29)11-9-18)14-24(26(30)34)31-23(21)13-17;1-24(2)11-21(29)28(22(30)12-24)13-14-3-8-17-18(15-4-6-16(25)7-5-15)10-20(23(26)31)27-19(17)9-14;1-3-24(2)12-21(29)28(23(24)31)13-14-4-9-17-18(15-5-7-16(25)8-6-15)11-20(22(26)30)27-19(17)10-14;1-23(2)21(30)28(22(31)27(23)3)12-13-4-9-16-17(14-5-7-15(24)8-6-14)11-19(20(25)29)26-18(16)10-13;22-15-4-2-14(3-5-15)18-10-16(11-23)24-19-9-13(1-6-17(18)19)12-25-20(26)7-8-21(25)27/h2-14H,15-16H2,1H3,(H2,30,34);3-10H,11-13H2,1-2H3,(H2,26,31);4-11H,3,12-13H2,1-2H3,(H2,26,30);4-11H,12H2,1-3H3,(H2,25,29);1-6,9-10H,7-8,12H2
• InChIKey: RTRBFAYELOHBTM-UHFFFAOYSA-N
• XLogP: 18.86
• TPSA: 450.74 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 20
• Rotatable Bonds: 21
• Heavy Atoms: 155
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2086.22
LogP ≤ 5	18.86
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	20

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}, {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide?

The IUPAC name of 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide (CID 160725628) is 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide.

What is the SMILES notation for 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide?

The canonical SMILES for 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide is CC1(C)CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C(=O)C1.CC1(c2ccccc2)CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1=O.CCC1(C)CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1=O.CN1C(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C(=O)C1(C)C.N#Cc1cc(-c2ccc(F)cc2)c2ccc(CN3C(=O)CCC3=O)cc2n1.

What is the InChIKey of 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide?

The InChIKey is RTRBFAYELOHBTM-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H22FN3O3.2C24H22FN3O3.C23H21FN4O3.C21H14FN3O2/c1-28(19-5-3-2-4-6-19)15-25(33)32(27(28)35)16-17-7-12-21-22(18-8-10-20(29)11-9-18)14-24(26(30)34)31-23(21)13-17;1-24(2)11-21(29)28(22(30)12-24)13-14-3-8-17-18(15-4-6-16(25)7-5-15)10-20(23(26)31)27-19(17)9-14;1-3-24(2)12-21(29)28(23(24)31)13-14-4-9-17-18(15-5-7-16(25)8-6-15)11-20(22(26)30)27-19(17)10-14;1-23(2)21(30)28(22(31)27(23)3)12-13-4-9-16-17(14-5-7-15(24)8-6-14)11-19(20(25)29)26-18(16)10-13;22-15-4-2-14(3-5-15)18-10-16(11-23)24-19-9-13(1-6-17(18)19)12-25-20(26)7-8-21(25)27/h2-14H,15-16H2,1H3,(H2,30,34);3-10H,11-13H2,1-2H3,(H2,26,31);4-11H,3,12-13H2,1-2H3,(H2,26,30);4-11H,12H2,1-3H3,(H2,25,29);1-6,9-10H,7-8,12H2.

What are the key properties of 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide?

7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide has a molecular weight of 2086.22 g/mol, XLogP of 18.86, 21 rotatable bonds, 4 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for 7-[(4,4-dimethyl-2,6-dioxopiperidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;7-[(3-ethyl-3-methyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)methyl]quinoline-2-carboxamide;4-(4-fluorophenyl)-7-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carboxamide is sourced from PubChem (CID 160725628), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).