5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde

C151H158Cl2I2N30O28 — CID 160734900

About 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde

5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde (PubChem CID 160734900) has the molecular formula C151H158Cl2I2N30O28 and a molecular weight of 3165.82 g/mol. Its IUPAC name is 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde.

Molecular Properties

• Compound Name: 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde
• PubChem CID: 160734900
• Molecular Formula: C151H158Cl2I2N30O28
• Molecular Weight: 3165.82 g/mol
• Exact Mass: 3162.93
• IUPAC Name: 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde
• SMILES: COc1nccc(I)c1-c1nc2cc3c(cc2[nH]1)C(=O)N(C1CCCCC1)C3=O.COc1nccc(I)c1C=O.Cc1ccc(OC[C@H](O)CN)c(C)c1.Cc1ccc(OC[C@H](O)CNc2cc[nH]c(=O)c2-c2nc3cc4c(cc3[nH]2)C(=O)N(C2CCCCC2)C4=O)c(C)c1.NC1CCCCC1.Nc1cc2c(cc1N)C(=O)N(C1CCCCC1)C2=O.Nc1cc2c(cc1[N+](=O)[O-])C(=O)N(C1CCCCC1)C2=O.Nc1cc2c(cc1[N+](=O)[O-])C(=O)NC2=O.O=C1c2cc3nc(-c4c(Cl)cc[nH]c4=O)[nH]c3cc2C(=O)N1C1CCCCC1.O=C1c2cc3nc(-c4c(Cl)cc[nH]c4=O)[nH]c3cc2C(=O)N1C1CCNCC1
• InChI: InChI=1S/C31H33N5O5.C21H19IN4O3.C20H17ClN4O3.C19H16ClN5O3.C14H15N3O4.C14H17N3O2.C11H17NO2.C8H5N3O4.C7H6INO2.C6H13N/c1-17-8-9-26(18(2)12-17)41-16-20(37)15-33-23-10-11-32-29(38)27(23)28-34-24-13-21-22(14-25(24)35-28)31(40)36(30(21)39)19-6-4-3-5-7-19;1-29-19-17(14(22)7-8-23-19)18-24-15-9-12-13(10-16(15)25-18)21(28)26(20(12)27)11-5-3-2-4-6-11;21-13-6-7-22-18(26)16(13)17-23-14-8-11-12(9-15(14)24-17)20(28)25(19(11)27)10-4-2-1-3-5-10;20-12-3-6-22-17(26)15(12)16-23-13-7-10-11(8-14(13)24-16)19(28)25(18(10)27)9-1-4-21-5-2-9;15-11-6-9-10(7-12(11)17(20)21)14(19)16(13(9)18)8-4-2-1-3-5-8;15-11-6-9-10(7-12(11)16)14(19)17(13(9)18)8-4-2-1-3-5-8;1-8-3-4-11(9(2)5-8)14-7-10(13)6-12;9-5-1-3-4(2-6(5)11(14)15)8(13)10-7(3)12;1-11-7-5(4-10)6(8)2-3-9-7;7-6-4-2-1-3-5-6/h8-14,19-20,37H,3-7,15-16H2,1-2H3,(H,34,35)(H2,32,33,38);7-11H,2-6H2,1H3,(H,24,25);6-10H,1-5H2,(H,22,26)(H,23,24);3,6-9,21H,1-2,4-5H2,(H,22,26)(H,23,24);6-8H,1-5,15H2;6-8H,1-5,15-16H2;3-5,10,13H,6-7,12H2,1-2H3;1-2H,9H2,(H,10,12,13);2-4H,1H3;6H,1-5,7H2/t20-;;;;;;10-;;;/m1.....1.../s1
• InChIKey: RUUYWBTXKYKKKD-XXOFKZTESA-N
• XLogP: 21.64
• TPSA: 870.44 Ų
• H-Bond Donors: 18
• H-Bond Acceptors: 42
• Rotatable Bonds: 25
• Heavy Atoms: 213
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3165.82
LogP ≤ 5	21.64
H-Bond Donors ≤ 5	18
H-Bond Acceptors ≤ 10	42

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'aldehyde', 'substructure': 'N/A'}, {'alert_name': 'aniline', 'substructure': 'N/A'}, {'alert_name': 'iodine', 'substructure': 'N/A'}, {'alert_name': 'nitro_group', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde?

The IUPAC name of 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde (CID 160734900) is 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde.

What is the SMILES notation for 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde?

The canonical SMILES for 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde is COc1nccc(I)c1-c1nc2cc3c(cc2[nH]1)C(=O)N(C1CCCCC1)C3=O.COc1nccc(I)c1C=O.Cc1ccc(OC[C@H](O)CN)c(C)c1.Cc1ccc(OC[C@H](O)CNc2cc[nH]c(=O)c2-c2nc3cc4c(cc3[nH]2)C(=O)N(C2CCCCC2)C4=O)c(C)c1.NC1CCCCC1.Nc1cc2c(cc1N)C(=O)N(C1CCCCC1)C2=O.Nc1cc2c(cc1[N+](=O)[O-])C(=O)N(C1CCCCC1)C2=O.Nc1cc2c(cc1[N+](=O)[O-])C(=O)NC2=O.O=C1c2cc3nc(-c4c(Cl)cc[nH]c4=O)[nH]c3cc2C(=O)N1C1CCCCC1.O=C1c2cc3nc(-c4c(Cl)cc[nH]c4=O)[nH]c3cc2C(=O)N1C1CCNCC1.

What is the InChIKey of 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde?

The InChIKey is RUUYWBTXKYKKKD-XXOFKZTESA-N. The full InChI is InChI=1S/C31H33N5O5.C21H19IN4O3.C20H17ClN4O3.C19H16ClN5O3.C14H15N3O4.C14H17N3O2.C11H17NO2.C8H5N3O4.C7H6INO2.C6H13N/c1-17-8-9-26(18(2)12-17)41-16-20(37)15-33-23-10-11-32-29(38)27(23)28-34-24-13-21-22(14-25(24)35-28)31(40)36(30(21)39)19-6-4-3-5-7-19;1-29-19-17(14(22)7-8-23-19)18-24-15-9-12-13(10-16(15)25-18)21(28)26(20(12)27)11-5-3-2-4-6-11;21-13-6-7-22-18(26)16(13)17-23-14-8-11-12(9-15(14)24-17)20(28)25(19(11)27)10-4-2-1-3-5-10;20-12-3-6-22-17(26)15(12)16-23-13-7-10-11(8-14(13)24-16)19(28)25(18(10)27)9-1-4-21-5-2-9;15-11-6-9-10(7-12(11)17(20)21)14(19)16(13(9)18)8-4-2-1-3-5-8;15-11-6-9-10(7-12(11)16)14(19)17(13(9)18)8-4-2-1-3-5-8;1-8-3-4-11(9(2)5-8)14-7-10(13)6-12;9-5-1-3-4(2-6(5)11(14)15)8(13)10-7(3)12;1-11-7-5(4-10)6(8)2-3-9-7;7-6-4-2-1-3-5-6/h8-14,19-20,37H,3-7,15-16H2,1-2H3,(H,34,35)(H2,32,33,38);7-11H,2-6H2,1H3,(H,24,25);6-10H,1-5H2,(H,22,26)(H,23,24);3,6-9,21H,1-2,4-5H2,(H,22,26)(H,23,24);6-8H,1-5,15H2;6-8H,1-5,15-16H2;3-5,10,13H,6-7,12H2,1-2H3;1-2H,9H2,(H,10,12,13);2-4H,1H3;6H,1-5,7H2/t20-;;;;;;10-;;;/m1.....1.../s1.

What are the key properties of 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde?

5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde has a molecular weight of 3165.82 g/mol, XLogP of 21.64, 25 rotatable bonds, 18 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for 5-amino-2-cyclohexyl-6-nitroisoindole-1,3-dione;(2R)-1-amino-3-(2,4-dimethylphenoxy)propan-2-ol;5-amino-6-nitroisoindole-1,3-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-cyclohexyl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;2-(4-chloro-2-oxo-1H-pyridin-3-yl)-6-piperidin-4-yl-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;cyclohexanamine;6-cyclohexyl-2-[4-[[(2R)-3-(2,4-dimethylphenoxy)-2-hydroxypropyl]amino]-2-oxo-1H-pyridin-3-yl]-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;6-cyclohexyl-2-(4-iodo-2-methoxy-3-pyridinyl)-3H-pyrrolo[3,4-f]benzimidazole-5,7-dione;5,6-diamino-2-cyclohexylisoindole-1,3-dione;4-iodo-2-methoxypyridine-3-carbaldehyde is sourced from PubChem (CID 160734900), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).