(7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one

C312H308F24N70O48 — CID 160757423

About (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one

(7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one (PubChem CID 160757423) has the molecular formula C312H308F24N70O48 and a molecular weight of 6262.29 g/mol. Its IUPAC name is (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one.

Molecular Properties

• Compound Name: (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one
• PubChem CID: 160757423
• Molecular Formula: C312H308F24N70O48
• Molecular Weight: 6262.29 g/mol
• Exact Mass: 6258.34
• IUPAC Name: (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one
• SMILES: CCO[C@@]1(C)c2nc(-c3cnc(OC)c(OC)c3)cc(C)c2C(=O)N1c1cnn(CC(F)(F)F)c1.CCOc1cncc(-c2cc(C)c3c(n2)[C@@H](C)N(c2cnn(CC(F)(F)F)c2)C3=O)c1.CCOc1cncc(-c2cc(C)c3c(n2)[C@H](C)N(c2cnn(CC(F)(F)F)c2)C3=O)c1.CCOc1ncc(-c2cc(C)c3c(n2)C(OC)N(c2cnn(CC(F)(F)F)c2)C3=O)cc1OC.CCn1ccc(N2C(=O)c3ccc(-c4cnc(OC)c(OC)c4)nc3C2C)n1.COc1cc(-c2cc(C)c3c(n2)C(O[C@H]2CCOC2)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1OC.COc1cc(-c2cc(C)c3c(n2)[C@@]2(CCCO2)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1OC.COc1cc(-c2cc(C)c3c(n2)[C@]2(CCCO2)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)C(C)N(c2ccc(N4CCC(O)C4)nc2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)C(C)N(c2ccc(N4CCC(O)CC4)nc2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)C(C)N(c2cccc(C(C)(C)C#N)n2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)C(C)N(c2ccn(C)n2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)C(C)N(c2cncc(C(C)(C)C#N)c2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)CN(c2cn(CC(F)(F)F)cn2)C3=O)cnc1OC
• InChI: InChI=1S/C25H27N5O4.C24H24F3N5O5.C24H25N5O4.2C24H23N5O3.2C23H22F3N5O4.C23H24F3N5O4.C22H22F3N5O4.2C21H20F3N5O2.C20H21N5O3.C19H16F3N5O3.C19H19N5O3/c1-15-23-19(5-6-20(28-23)16-12-21(33-2)24(34-3)27-13-16)25(32)30(15)17-4-7-22(26-14-17)29-10-8-18(31)9-11-29;1-13-6-17(14-7-18(34-2)21(35-3)28-8-14)30-20-19(13)22(33)32(23(20)37-16-4-5-36-11-16)15-9-29-31(10-15)12-24(25,26)27;1-14-22-18(5-6-19(27-22)15-10-20(32-2)23(33-3)26-11-15)24(31)29(14)16-4-7-21(25-12-16)28-9-8-17(30)13-28;1-14-21-18(6-7-19(28-21)15-8-20(31-4)22(32-5)27-10-15)23(30)29(14)17-9-16(11-26-12-17)24(2,3)13-25;1-14-21-16(9-10-17(27-21)15-11-18(31-4)22(32-5)26-12-15)23(30)29(14)20-8-6-7-19(28-20)24(2,3)13-25;2*1-13-7-16(14-8-17(33-2)20(34-3)27-9-14)29-19-18(13)21(32)31(22(19)5-4-6-35-22)15-10-28-30(11-15)12-23(24,25)26;1-6-35-22(3)19-18(21(32)31(22)15-10-28-30(11-15)12-23(24,25)26)13(2)7-16(29-19)14-8-17(33-4)20(34-5)27-9-14;1-5-34-19-16(32-3)7-13(8-26-19)15-6-12(2)17-18(28-15)21(33-4)30(20(17)31)14-9-27-29(10-14)11-22(23,24)25;2*1-4-31-16-6-14(7-25-9-16)17-5-12(2)18-19(27-17)13(3)29(20(18)30)15-8-26-28(10-15)11-21(22,23)24;1-5-24-9-8-17(23-24)25-12(2)18-14(20(25)26)6-7-15(22-18)13-10-16(27-3)19(28-4)21-11-13;1-29-15-5-11(6-23-17(15)30-2)13-4-3-12-14(25-13)7-27(18(12)28)16-8-26(10-24-16)9-19(20,21)22;1-11-17-13(19(25)24(11)16-7-8-23(2)22-16)5-6-14(21-17)12-9-15(26-3)18(27-4)20-10-12/h4-7,12-15,18,31H,8-11H2,1-3H3;6-10,16,23H,4-5,11-12H2,1-3H3;4-7,10-12,14,17,30H,8-9,13H2,1-3H3;2*6-12,14H,1-5H3;2*7-11H,4-6,12H2,1-3H3;7-11H,6,12H2,1-5H3;6-10,21H,5,11H2,1-4H3;2*5-10,13H,4,11H2,1-3H3;6-12H,5H2,1-4H3;3-6,8,10H,7,9H2,1-2H3;5-11H,1-4H3/t;16-,23?;;;;3*22-;;2*13-;;;/m.0...100.10.../s1
• InChIKey: RXPPGFSWFRYWAK-XOBOMREASA-N
• XLogP: 51.12
• TPSA: 1264.90 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 104
• Rotatable Bonds: 75
• Heavy Atoms: 454
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	6262.29
LogP ≤ 5	51.12
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	104

Frequently Asked Questions

What is the IUPAC name of (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one?

The IUPAC name of (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one (CID 160757423) is (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one.

What is the SMILES notation for (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one?

The canonical SMILES for (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one is CCO[C@@]1(C)c2nc(-c3cnc(OC)c(OC)c3)cc(C)c2C(=O)N1c1cnn(CC(F)(F)F)c1.CCOc1cncc(-c2cc(C)c3c(n2)[C@@H](C)N(c2cnn(CC(F)(F)F)c2)C3=O)c1.CCOc1cncc(-c2cc(C)c3c(n2)[C@H](C)N(c2cnn(CC(F)(F)F)c2)C3=O)c1.CCOc1ncc(-c2cc(C)c3c(n2)C(OC)N(c2cnn(CC(F)(F)F)c2)C3=O)cc1OC.CCn1ccc(N2C(=O)c3ccc(-c4cnc(OC)c(OC)c4)nc3C2C)n1.COc1cc(-c2cc(C)c3c(n2)C(O[C@H]2CCOC2)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1OC.COc1cc(-c2cc(C)c3c(n2)[C@@]2(CCCO2)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1OC.COc1cc(-c2cc(C)c3c(n2)[C@]2(CCCO2)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)C(C)N(c2ccc(N4CCC(O)C4)nc2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)C(C)N(c2ccc(N4CCC(O)CC4)nc2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)C(C)N(c2cccc(C(C)(C)C#N)n2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)C(C)N(c2ccn(C)n2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)C(C)N(c2cncc(C(C)(C)C#N)c2)C3=O)cnc1OC.COc1cc(-c2ccc3c(n2)CN(c2cn(CC(F)(F)F)cn2)C3=O)cnc1OC.

What is the InChIKey of (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one?

The InChIKey is RXPPGFSWFRYWAK-XOBOMREASA-N. The full InChI is InChI=1S/C25H27N5O4.C24H24F3N5O5.C24H25N5O4.2C24H23N5O3.2C23H22F3N5O4.C23H24F3N5O4.C22H22F3N5O4.2C21H20F3N5O2.C20H21N5O3.C19H16F3N5O3.C19H19N5O3/c1-15-23-19(5-6-20(28-23)16-12-21(33-2)24(34-3)27-13-16)25(32)30(15)17-4-7-22(26-14-17)29-10-8-18(31)9-11-29;1-13-6-17(14-7-18(34-2)21(35-3)28-8-14)30-20-19(13)22(33)32(23(20)37-16-4-5-36-11-16)15-9-29-31(10-15)12-24(25,26)27;1-14-22-18(5-6-19(27-22)15-10-20(32-2)23(33-3)26-11-15)24(31)29(14)16-4-7-21(25-12-16)28-9-8-17(30)13-28;1-14-21-18(6-7-19(28-21)15-8-20(31-4)22(32-5)27-10-15)23(30)29(14)17-9-16(11-26-12-17)24(2,3)13-25;1-14-21-16(9-10-17(27-21)15-11-18(31-4)22(32-5)26-12-15)23(30)29(14)20-8-6-7-19(28-20)24(2,3)13-25;2*1-13-7-16(14-8-17(33-2)20(34-3)27-9-14)29-19-18(13)21(32)31(22(19)5-4-6-35-22)15-10-28-30(11-15)12-23(24,25)26;1-6-35-22(3)19-18(21(32)31(22)15-10-28-30(11-15)12-23(24,25)26)13(2)7-16(29-19)14-8-17(33-4)20(34-5)27-9-14;1-5-34-19-16(32-3)7-13(8-26-19)15-6-12(2)17-18(28-15)21(33-4)30(20(17)31)14-9-27-29(10-14)11-22(23,24)25;2*1-4-31-16-6-14(7-25-9-16)17-5-12(2)18-19(27-17)13(3)29(20(18)30)15-8-26-28(10-15)11-21(22,23)24;1-5-24-9-8-17(23-24)25-12(2)18-14(20(25)26)6-7-15(22-18)13-10-16(27-3)19(28-4)21-11-13;1-29-15-5-11(6-23-17(15)30-2)13-4-3-12-14(25-13)7-27(18(12)28)16-8-26(10-24-16)9-19(20,21)22;1-11-17-13(19(25)24(11)16-7-8-23(2)22-16)5-6-14(21-17)12-9-15(26-3)18(27-4)20-10-12/h4-7,12-15,18,31H,8-11H2,1-3H3;6-10,16,23H,4-5,11-12H2,1-3H3;4-7,10-12,14,17,30H,8-9,13H2,1-3H3;2*6-12,14H,1-5H3;2*7-11H,4-6,12H2,1-3H3;7-11H,6,12H2,1-5H3;6-10,21H,5,11H2,1-4H3;2*5-10,13H,4,11H2,1-3H3;6-12H,5H2,1-4H3;3-6,8,10H,7,9H2,1-2H3;5-11H,1-4H3/t;16-,23?;;;;3*22-;;2*13-;;;/m.0...100.10.../s1.

What are the key properties of (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one?

(7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one has a molecular weight of 6262.29 g/mol, XLogP of 51.12, 75 rotatable bonds, 2 hydrogen bond donors, and 104 hydrogen bond acceptors.

Where does this data come from?

All data for (7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-(1-ethylpyrazol-3-yl)-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(4-hydroxypiperidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-7-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-6-(1-methylpyrazol-3-yl)-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5,6-dimethoxy-3-pyridinyl)-4-methyl-7-[(3S)-oxolan-3-yl]oxy-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-3-pyridinyl]-2-methylpropanenitrile;2-[6-[2-(5,6-dimethoxy-3-pyridinyl)-7-methyl-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl]-2-pyridinyl]-2-methylpropanenitrile;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(5,6-dimethoxy-3-pyridinyl)-6-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one is sourced from PubChem (CID 160757423), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).