[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone

C150H157ClF6N18O21 — CID 160776479

About [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone

[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone (PubChem CID 160776479) has the molecular formula C150H157ClF6N18O21 and a molecular weight of 2697.45 g/mol. Its IUPAC name is [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone.

Molecular Properties

• Compound Name: [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone
• PubChem CID: 160776479
• Molecular Formula: C150H157ClF6N18O21
• Molecular Weight: 2697.45 g/mol
• Exact Mass: 2695.14
• IUPAC Name: [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone
• SMILES: CNC(=O)C1CCN(C(=O)c2cnoc2-c2ccc(C)cc2)CC1.COC[C@H]1CCCN1C(=O)c1cnoc1-c1ccc(C)cc1.Cc1ccc(-c2oncc2C(=O)N2CCC(C(F)(F)F)CC2)cc1.Cc1ccc(-c2oncc2C(=O)N2CCC(O)(c3ccc(Cl)cc3)CC2)cc1.Cc1ccc(-c2oncc2C(=O)N2CCC(O)(c3ccccc3)CC2)cc1.Cc1ccc(-c2oncc2C(=O)N2CCCC(C(F)(F)F)C2)cc1.Cc1ccc(-c2oncc2C(=O)N2CCCC(O)C2)cc1.Cc1ccc(-c2oncc2C(=O)N2CCCC2Cc2cccnc2)cc1
• InChI: InChI=1S/C22H21ClN2O3.C22H22N2O3.C21H21N3O2.C18H21N3O3.2C17H17F3N2O2.C17H20N2O3.C16H18N2O3/c1-15-2-4-16(5-3-15)20-19(14-24-28-20)21(26)25-12-10-22(27,11-13-25)17-6-8-18(23)9-7-17;1-16-7-9-17(10-8-16)20-19(15-23-27-20)21(25)24-13-11-22(26,12-14-24)18-5-3-2-4-6-18;1-15-6-8-17(9-7-15)20-19(14-23-26-20)21(25)24-11-3-5-18(24)12-16-4-2-10-22-13-16;1-12-3-5-13(6-4-12)16-15(11-20-24-16)18(23)21-9-7-14(8-10-21)17(22)19-2;1-11-2-4-12(5-3-11)15-14(10-21-24-15)16(23)22-8-6-13(7-9-22)17(18,19)20;1-11-4-6-12(7-5-11)15-14(9-21-24-15)16(23)22-8-2-3-13(10-22)17(18,19)20;1-12-5-7-13(8-6-12)16-15(10-18-22-16)17(20)19-9-3-4-14(19)11-21-2;1-11-4-6-12(7-5-11)15-14(9-17-21-15)16(20)18-8-2-3-13(19)10-18/h2-9,14,27H,10-13H2,1H3;2-10,15,26H,11-14H2,1H3;2,4,6-10,13-14,18H,3,5,11-12H2,1H3;3-6,11,14H,7-10H2,1-2H3,(H,19,22);2-5,10,13H,6-9H2,1H3;4-7,9,13H,2-3,8,10H2,1H3;5-8,10,14H,3-4,9,11H2,1-2H3;4-7,9,13,19H,2-3,8,10H2,1H3/t;;;;;;14-;/m......1./s1
• InChIKey: RZZYEUXAWNDDES-NMKAKALHSA-N
• XLogP: 27.62
• TPSA: 482.63 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 30
• Rotatable Bonds: 23
• Heavy Atoms: 196
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2697.45
LogP ≤ 5	27.62
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	30

Frequently Asked Questions

What is the IUPAC name of [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone?

The IUPAC name of [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone (CID 160776479) is [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone.

What is the SMILES notation for [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone?

The canonical SMILES for [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone is CNC(=O)C1CCN(C(=O)c2cnoc2-c2ccc(C)cc2)CC1.COC[C@H]1CCCN1C(=O)c1cnoc1-c1ccc(C)cc1.Cc1ccc(-c2oncc2C(=O)N2CCC(C(F)(F)F)CC2)cc1.Cc1ccc(-c2oncc2C(=O)N2CCC(O)(c3ccc(Cl)cc3)CC2)cc1.Cc1ccc(-c2oncc2C(=O)N2CCC(O)(c3ccccc3)CC2)cc1.Cc1ccc(-c2oncc2C(=O)N2CCCC(C(F)(F)F)C2)cc1.Cc1ccc(-c2oncc2C(=O)N2CCCC(O)C2)cc1.Cc1ccc(-c2oncc2C(=O)N2CCCC2Cc2cccnc2)cc1.

What is the InChIKey of [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone?

The InChIKey is RZZYEUXAWNDDES-NMKAKALHSA-N. The full InChI is InChI=1S/C22H21ClN2O3.C22H22N2O3.C21H21N3O2.C18H21N3O3.2C17H17F3N2O2.C17H20N2O3.C16H18N2O3/c1-15-2-4-16(5-3-15)20-19(14-24-28-20)21(26)25-12-10-22(27,11-13-25)17-6-8-18(23)9-7-17;1-16-7-9-17(10-8-16)20-19(15-23-27-20)21(25)24-13-11-22(26,12-14-24)18-5-3-2-4-6-18;1-15-6-8-17(9-7-15)20-19(14-23-26-20)21(25)24-11-3-5-18(24)12-16-4-2-10-22-13-16;1-12-3-5-13(6-4-12)16-15(11-20-24-16)18(23)21-9-7-14(8-10-21)17(22)19-2;1-11-2-4-12(5-3-11)15-14(10-21-24-15)16(23)22-8-6-13(7-9-22)17(18,19)20;1-11-4-6-12(7-5-11)15-14(9-21-24-15)16(23)22-8-2-3-13(10-22)17(18,19)20;1-12-5-7-13(8-6-12)16-15(10-18-22-16)17(20)19-9-3-4-14(19)11-21-2;1-11-4-6-12(7-5-11)15-14(9-17-21-15)16(20)18-8-2-3-13(19)10-18/h2-9,14,27H,10-13H2,1H3;2-10,15,26H,11-14H2,1H3;2,4,6-10,13-14,18H,3,5,11-12H2,1H3;3-6,11,14H,7-10H2,1-2H3,(H,19,22);2-5,10,13H,6-9H2,1H3;4-7,9,13H,2-3,8,10H2,1H3;5-8,10,14H,3-4,9,11H2,1-2H3;4-7,9,13,19H,2-3,8,10H2,1H3/t;;;;;;14-;/m......1./s1.

What are the key properties of [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone?

[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone has a molecular weight of 2697.45 g/mol, XLogP of 27.62, 23 rotatable bonds, 4 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(4-hydroxy-4-phenylpiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;(3-hydroxypiperidin-1-yl)-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]-[5-(4-methylphenyl)-1,2-oxazol-4-yl]methanone;N-methyl-1-[5-(4-methylphenyl)-1,2-oxazole-4-carbonyl]piperidine-4-carboxamide;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[2-(pyridin-3-ylmethyl)pyrrolidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[3-(trifluoromethyl)piperidin-1-yl]methanone;[5-(4-methylphenyl)-1,2-oxazol-4-yl]-[4-(trifluoromethyl)piperidin-1-yl]methanone is sourced from PubChem (CID 160776479), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).