3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide

C150H130F19N41O10S — CID 160782257

IUPAC3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide
SMILESCC(=O)N1CCN(c2cccc(C(=O)Nc3ccc(-n4nc(-c5cccnc5)cc4C(F)(F)F)nn3)c2)CC1.CC1CC(C)CN(c2cccc(C(=O)Nc3ccc(-n4nc(-c5cccnc5)cc4C(F)(F)F)nn3)c2)C1.CN1CCN(c2cccc(C(=O)Nc3ccc(-n4nc(-c5cccnc5)cc4C(F)(F)F)cn3)c2)CC1.COc1ccc(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C(F)(F)F)cn2)cn1.O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)cn1)c1ccc(F)c(S(=O)(=O)N2CCCCC2)c1.O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nn1)c1cccc(N2CCCC2)c1
InChIInChI=1S/C27H26F3N7O.C26H22F4N6O3S.C26H23F3N8O2.C26H24F3N7O.C24H20F3N7O.C21H15F3N6O2/c1-17-11-18(2)16-36(15-17)21-7-3-5-19(12-21)26(38)32-24-8-9-25(34-33-24)37-23(27(28,29)30)13-22(35-37)20-6-4-10-31-14-20;27-20-8-6-17(13-22(20)40(38,39)35-11-2-1-3-12-35)25(37)33-24-9-7-19(16-32-24)36-23(26(28,29)30)14-21(34-36)18-5-4-10-31-15-18;1-17(38)35-10-12-36(13-11-35)20-6-2-4-18(14-20)25(39)31-23-7-8-24(33-32-23)37-22(26(27,28)29)15-21(34-37)19-5-3-9-30-16-19;1-34-10-12-35(13-11-34)20-6-2-4-18(14-20)25(37)32-24-8-7-21(17-31-24)36-23(26(27,28)29)15-22(33-36)19-5-3-9-30-16-19;25-24(26,27)20-14-19(17-6-4-10-28-15-17)32-34(20)22-9-8-21(30-31-22)29-23(35)16-5-3-7-18(13-16)33-11-1-2-12-33;1-32-19-7-4-14(11-27-19)20(31)28-18-6-5-15(12-26-18)30-17(21(22,23)24)9-16(29-30)13-3-2-8-25-10-13/h3-10,12-14,17-18H,11,15-16H2,1-2H3,(H,32,33,38);4-10,13-16H,1-3,11-12H2,(H,32,33,37);2-9,14-16H,10-13H2,1H3,(H,31,32,39);2-9,14-17H,10-13H2,1H3,(H,31,32,37);3-10,13-15H,1-2,11-12H2,(H,29,30,35);2-12H,1H3,(H,26,28,31)
InChIKeySASQSVJDMAKTCS-UHFFFAOYSA-N
MW3060.00 g/mol
LogP27.01
Rot. Bonds31

About 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide

3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide (PubChem CID 160782257) has the molecular formula C150H130F19N41O10S and a molecular weight of 3060.00 g/mol. Its IUPAC name is 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide.

Molecular Properties

Compound Name3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide
PubChem CID160782257
Molecular FormulaC150H130F19N41O10S
Molecular Weight3060.00 g/mol
Exact Mass3058.03
IUPAC Name3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide
SMILESCC(=O)N1CCN(c2cccc(C(=O)Nc3ccc(-n4nc(-c5cccnc5)cc4C(F)(F)F)nn3)c2)CC1.CC1CC(C)CN(c2cccc(C(=O)Nc3ccc(-n4nc(-c5cccnc5)cc4C(F)(F)F)nn3)c2)C1.CN1CCN(c2cccc(C(=O)Nc3ccc(-n4nc(-c5cccnc5)cc4C(F)(F)F)cn3)c2)CC1.COc1ccc(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C(F)(F)F)cn2)cn1.O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)cn1)c1ccc(F)c(S(=O)(=O)N2CCCCC2)c1.O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nn1)c1cccc(N2CCCC2)c1
InChIInChI=1S/C27H26F3N7O.C26H22F4N6O3S.C26H23F3N8O2.C26H24F3N7O.C24H20F3N7O.C21H15F3N6O2/c1-17-11-18(2)16-36(15-17)21-7-3-5-19(12-21)26(38)32-24-8-9-25(34-33-24)37-23(27(28,29)30)13-22(35-37)20-6-4-10-31-14-20;27-20-8-6-17(13-22(20)40(38,39)35-11-2-1-3-12-35)25(37)33-24-9-7-19(16-32-24)36-23(26(28,29)30)14-21(34-36)18-5-4-10-31-15-18;1-17(38)35-10-12-36(13-11-35)20-6-2-4-18(14-20)25(39)31-23-7-8-24(33-32-23)37-22(26(27,28)29)15-21(34-37)19-5-3-9-30-16-19;1-34-10-12-35(13-11-34)20-6-2-4-18(14-20)25(37)32-24-8-7-21(17-31-24)36-23(26(27,28)29)15-22(33-36)19-5-3-9-30-16-19;25-24(26,27)20-14-19(17-6-4-10-28-15-17)32-34(20)22-9-8-21(30-31-22)29-23(35)16-5-3-7-18(13-16)33-11-1-2-12-33;1-32-19-7-4-14(11-27-19)20(31)28-18-6-5-15(12-26-18)30-17(21(22,23)24)9-16(29-30)13-3-2-8-25-10-13/h3-10,12-14,17-18H,11,15-16H2,1-2H3,(H,32,33,38);4-10,13-16H,1-3,11-12H2,(H,32,33,37);2-9,14-16H,10-13H2,1H3,(H,31,32,39);2-9,14-17H,10-13H2,1H3,(H,31,32,37);3-10,13-15H,1-2,11-12H2,(H,29,30,35);2-12H,1H3,(H,26,28,31)
InChIKeySASQSVJDMAKTCS-UHFFFAOYSA-N
XLogP27.01
TPSA570.88 Ų
H-Bond Donors6
H-Bond Acceptors43
Rotatable Bonds31
Heavy Atoms221
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003060.00
LogP ≤ 527.01
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1043

Analyze 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide with MolForge

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Launch Full Analysis

Related Compounds

3-cyano-N-[6-[3-(6-oxo-1H-pyridin-3-yl)-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(6-fluoro-3-pyridinyl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-(6-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-[4-(pyrrolidine-1-carbonyl)phenyl]benzamide;4-methylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;3-morpholin-4-yl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;4-morpholin-4-yl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide
CID 157796517
6-methoxy-N-[5-(5-methyl-3-pyridin-3-ylpyrazol-1-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(5-methyl-3-pyridin-3-ylpyrazol-1-yl)-2-pyridinyl]pyridine-3-carboxamide;N-[5-(5-methyl-3-pyridin-3-ylpyrazol-1-yl)-2-pyridinyl]pyrimidine-5-carboxamide;N-[5-(5-methyl-3-pyridin-3-ylpyrazol-1-yl)-2-pyridinyl]-6-(trifluoromethoxy)pyridine-3-carboxamide;N-[5-(5-methyl-3-pyridin-3-ylpyrazol-1-yl)-2-pyridinyl]-6-(trifluoromethyl)pyridine-3-carboxamide
CID 158039847
4-cyano-N-[3-pyridin-4-yl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]pyrazol-5-yl]benzamide;N-[1-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-pyridin-4-ylpyrazol-5-yl]acetamide;1-[1-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-pyridin-4-ylpyrazol-5-yl]pyrrolidine-2,5-dione;4-methoxy-N-[3-pyridin-4-yl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]pyrazol-5-yl]benzenesulfonamide
CID 158270048
1-[2-(cyclopropylamino)-2-oxoethyl]-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;ethyl 1-[3-[[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]carbamoyl]phenyl]piperidine-3-carboxylate;3-[4-(2-methoxyethyl)piperazin-1-yl]-N-[5-[3-(6-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;3-[4-(2-methoxyethyl)piperazin-1-yl]-N-[5-[3-(oxan-4-yl)-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;1-[2-(2-morpholin-4-ylethylamino)-2-oxoethyl]-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide
CID 158442339
3-cyano-4-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;2-cyano-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;1-[2-(dimethylamino)-2-oxoethyl]-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(dimethylsulfamoyl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;3-morpholin-4-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;3-(propan-2-ylsulfamoyl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide
CID 158588051
4-(benzylsulfamoyl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;1-[3-(dimethylamino)-3-oxopropyl]-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;methyl 3-[[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]carbamoyl]benzoate;1-(3-morpholin-4-yl-3-oxopropyl)-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;6-oxo-1-[2-oxo-2-(pyridin-3-ylmethylamino)ethyl]-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide
CID 158669494
N-[(2R)-3-[4-[[(2S)-2-cyclohexyl-2-[[2,2-difluoro-2-(6-methoxy-3-pyridinyl)acetyl]amino]acetyl]amino]-3-fluorophenyl]-1-(4-methylpiperazin-1-yl)-1-oxopropan-2-yl]thiadiazole-5-carboxamide;N-[(2R)-3-[4-[[(2S)-2-cyclohexyl-2-[(2-ethylpyrazole-3-carbonyl)amino]acetyl]amino]-3-fluorophenyl]-1-(4-methylpiperazin-1-yl)-1-oxopropan-2-yl]thiadiazole-5-carboxamide;N-[(1S)-1-cyclohexyl-2-[2-fluoro-4-[(2R)-3-(4-methylpiperazin-1-yl)-2-[[2-(1-methylpiperidin-4-yl)pyrazole-3-carbonyl]amino]-3-oxopropyl]anilino]-2-oxoethyl]-2-ethylpyrazole-3-carboxamide;N-[(1S)-1-cyclohexyl-2-[2-fluoro-4-[(2R)-3-(4-methylpiperazin-1-yl)-3-oxo-2-(pyrido[3,4-d]pyrimidin-4-ylamino)propyl]anilino]-2-oxoethyl]-2-ethylpyrazole-3-carboxamide
CID 159011175
3-cyano-5-fluoro-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;3-(6-fluoro-3-pyridinyl)-N-[6-[3-(6-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;1-(4-methylphenyl)-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;1-N-methyl-4-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzene-1,4-dicarboxamide;2-methylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-oxo-1-(pyridin-2-ylmethyl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide
CID 159070011
3-(benzylsulfamoyl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;1-[2-(dimethylamino)-2-oxoethyl]-6-oxo-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-3-pyridinyl]pyridine-3-carboxamide;ethyl 3-[2-oxo-5-[[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]carbamoyl]-1-pyridinyl]propanoate;4-fluoro-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;1-[2-(2-methoxyethylamino)-2-oxoethyl]-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;1-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]-3-[[2-(trifluoromethoxy)phenyl]methyl]urea
CID 159323137
1-(2-ethoxyethyl)-N-[5-[3-ethoxy-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]-6-oxopyridine-3-carboxamide;1-(2-ethoxyethyl)-N-[6-[3-(oxan-4-yl)-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-6-oxopyridine-3-carboxamide;1-[(2-ethoxyphenyl)methyl]-3-[[4-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]phenyl]methyl]urea;4-(methylsulfamoyl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;1-[[4-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]phenyl]methyl]-3-[[2-(trifluoromethoxy)phenyl]methyl]urea;4-[[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]carbamoyl]benzoic acid
CID 159638874
1-benzyl-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;6-ethoxy-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]pyridine-3-carboxamide;3-(6-fluoro-3-pyridinyl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-morpholin-4-yl-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;6-morpholin-4-yl-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]pyridine-3-carboxamide;6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]-1-(2-pyrrolidin-1-ylethyl)pyridine-3-carboxamide
CID 159961068
1-acetyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]piperidine-4-carboxamide;6-phenoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;6-phenoxy-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-3-pyridinyl]pyridine-3-carboxamide;N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]oxolane-3-carboxamide;N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-4-carboxamide;N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]-3-pyrimidin-5-ylbenzamide
CID 160271899

Frequently Asked Questions

What is the IUPAC name of 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide?
The IUPAC name of 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide (CID 160782257) is 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide.
What is the SMILES notation for 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide?
The canonical SMILES for 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide is CC(=O)N1CCN(c2cccc(C(=O)Nc3ccc(-n4nc(-c5cccnc5)cc4C(F)(F)F)nn3)c2)CC1.CC1CC(C)CN(c2cccc(C(=O)Nc3ccc(-n4nc(-c5cccnc5)cc4C(F)(F)F)nn3)c2)C1.CN1CCN(c2cccc(C(=O)Nc3ccc(-n4nc(-c5cccnc5)cc4C(F)(F)F)cn3)c2)CC1.COc1ccc(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C(F)(F)F)cn2)cn1.O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)cn1)c1ccc(F)c(S(=O)(=O)N2CCCCC2)c1.O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nn1)c1cccc(N2CCCC2)c1.
What is the InChIKey of 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide?
The InChIKey is SASQSVJDMAKTCS-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H26F3N7O.C26H22F4N6O3S.C26H23F3N8O2.C26H24F3N7O.C24H20F3N7O.C21H15F3N6O2/c1-17-11-18(2)16-36(15-17)21-7-3-5-19(12-21)26(38)32-24-8-9-25(34-33-24)37-23(27(28,29)30)13-22(35-37)20-6-4-10-31-14-20;27-20-8-6-17(13-22(20)40(38,39)35-11-2-1-3-12-35)25(37)33-24-9-7-19(16-32-24)36-23(26(28,29)30)14-21(34-36)18-5-4-10-31-15-18;1-17(38)35-10-12-36(13-11-35)20-6-2-4-18(14-20)25(39)31-23-7-8-24(33-32-23)37-22(26(27,28)29)15-21(34-37)19-5-3-9-30-16-19;1-34-10-12-35(13-11-34)20-6-2-4-18(14-20)25(37)32-24-8-7-21(17-31-24)36-23(26(27,28)29)15-22(33-36)19-5-3-9-30-16-19;25-24(26,27)20-14-19(17-6-4-10-28-15-17)32-34(20)22-9-8-21(30-31-22)29-23(35)16-5-3-7-18(13-16)33-11-1-2-12-33;1-32-19-7-4-14(11-27-19)20(31)28-18-6-5-15(12-26-18)30-17(21(22,23)24)9-16(29-30)13-3-2-8-25-10-13/h3-10,12-14,17-18H,11,15-16H2,1-2H3,(H,32,33,38);4-10,13-16H,1-3,11-12H2,(H,32,33,37);2-9,14-16H,10-13H2,1H3,(H,31,32,39);2-9,14-17H,10-13H2,1H3,(H,31,32,37);3-10,13-15H,1-2,11-12H2,(H,29,30,35);2-12H,1H3,(H,26,28,31).
What are the key properties of 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide?
3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide has a molecular weight of 3060.00 g/mol, XLogP of 27.01, 31 rotatable bonds, 6 hydrogen bond donors, and 43 hydrogen bond acceptors.
Where does this data come from?
All data for 3-(4-acetylpiperazin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;3-(3,5-dimethylpiperidin-1-yl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-fluoro-3-piperidin-1-ylsulfonyl-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;6-methoxy-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;3-(4-methylpiperazin-1-yl)-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]-3-pyrrolidin-1-ylbenzamide is sourced from PubChem (CID 160782257), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).