4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide

C103H90Cl10F3N21O5 — CID 160786662

IUPAC4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide
SMILESCc1cc(NC(=O)C(CCN)c2ccc(Cl)c(Cl)c2)cc2cn[nH]c12.NCC(C(=O)Nc1cc(-c2ccccc2)c2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1.NCCC(C(=O)Nc1cc(-c2ccccc2)c2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1.NCCC(C(=O)Nc1cc(-c2ccccc2Cl)c2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1.NCCC(C(=O)Nc1ccc2[nH]ncc2c1)c1cc(C(F)(F)F)cc(Cl)n1
InChIInChI=1S/C23H19Cl3N4O.C23H20Cl2N4O.C22H18Cl2N4O.C18H18Cl2N4O.C17H15ClF3N5O/c24-19-4-2-1-3-17(19)18-11-15(9-14-12-28-30-22(14)18)29-23(31)16(7-8-27)13-5-6-20(25)21(26)10-13;24-20-7-6-15(11-21(20)25)18(8-9-26)23(30)28-17-10-16-13-27-29-22(16)19(12-17)14-4-2-1-3-5-14;23-19-7-6-14(9-20(19)24)18(11-25)22(29)27-16-8-15-12-26-28-21(15)17(10-16)13-4-2-1-3-5-13;1-10-6-13(7-12-9-22-24-17(10)12)23-18(25)14(4-5-21)11-2-3-15(19)16(20)8-11;18-15-7-10(17(19,20)21)6-14(25-15)12(3-4-22)16(27)24-11-1-2-13-9(5-11)8-23-26-13/h1-6,9-12,16H,7-8,27H2,(H,28,30)(H,29,31);1-7,10-13,18H,8-9,26H2,(H,27,29)(H,28,30);1-10,12,18H,11,25H2,(H,26,28)(H,27,29);2-3,6-9,14H,4-5,21H2,1H3,(H,22,24)(H,23,25);1-2,5-8,12H,3-4,22H2,(H,23,26)(H,24,27)
InChIKeySBHKBVZJBPRANS-UHFFFAOYSA-N
MW2113.52 g/mol
LogP25.04
Rot. Bonds27

About 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide

4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide (PubChem CID 160786662) has the molecular formula C103H90Cl10F3N21O5 and a molecular weight of 2113.52 g/mol. Its IUPAC name is 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide.

Molecular Properties

Compound Name4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide
PubChem CID160786662
Molecular FormulaC103H90Cl10F3N21O5
Molecular Weight2113.52 g/mol
Exact Mass2107.43
IUPAC Name4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide
SMILESCc1cc(NC(=O)C(CCN)c2ccc(Cl)c(Cl)c2)cc2cn[nH]c12.NCC(C(=O)Nc1cc(-c2ccccc2)c2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1.NCCC(C(=O)Nc1cc(-c2ccccc2)c2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1.NCCC(C(=O)Nc1cc(-c2ccccc2Cl)c2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1.NCCC(C(=O)Nc1ccc2[nH]ncc2c1)c1cc(C(F)(F)F)cc(Cl)n1
InChIInChI=1S/C23H19Cl3N4O.C23H20Cl2N4O.C22H18Cl2N4O.C18H18Cl2N4O.C17H15ClF3N5O/c24-19-4-2-1-3-17(19)18-11-15(9-14-12-28-30-22(14)18)29-23(31)16(7-8-27)13-5-6-20(25)21(26)10-13;24-20-7-6-15(11-21(20)25)18(8-9-26)23(30)28-17-10-16-13-27-29-22(16)19(12-17)14-4-2-1-3-5-14;23-19-7-6-14(9-20(19)24)18(11-25)22(29)27-16-8-15-12-26-28-21(15)17(10-16)13-4-2-1-3-5-13;1-10-6-13(7-12-9-22-24-17(10)12)23-18(25)14(4-5-21)11-2-3-15(19)16(20)8-11;18-15-7-10(17(19,20)21)6-14(25-15)12(3-4-22)16(27)24-11-1-2-13-9(5-11)8-23-26-13/h1-6,9-12,16H,7-8,27H2,(H,28,30)(H,29,31);1-7,10-13,18H,8-9,26H2,(H,27,29)(H,28,30);1-10,12,18H,11,25H2,(H,26,28)(H,27,29);2-3,6-9,14H,4-5,21H2,1H3,(H,22,24)(H,23,25);1-2,5-8,12H,3-4,22H2,(H,23,26)(H,24,27)
InChIKeySBHKBVZJBPRANS-UHFFFAOYSA-N
XLogP25.04
TPSA431.89 Ų
H-Bond Donors15
H-Bond Acceptors16
Rotatable Bonds27
Heavy Atoms142
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002113.52
LogP ≤ 525.04
H-Bond Donors ≤ 515
H-Bond Acceptors ≤ 1016

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Analyze 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide with MolForge

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Related Compounds

3-amino-2-(3,4-dichlorophenyl)-N-[3-(3-isocyanoanilino)-1H-indazol-5-yl]propanamide;3-amino-2-(3,4-dichlorophenyl)-N-(3-methyl-2H-indazol-5-yl)propanamide;3-amino-2-(3,4-dichlorophenyl)-N-(3-phenyl-1H-indazol-5-yl)propanamide;4-amino-2-phenyl-N-[3-(3-phenylphenyl)-1H-indazol-5-yl]butanamide;4-amino-2-phenyl-N-[3-(3-propan-2-ylphenyl)-1H-indazol-5-yl]butanamide;4-amino-2-phenyl-N-[3-[3-(trifluoromethyl)phenyl]-1H-indazol-5-yl]butanamide
CID 157891067
(2S)-2-acetamido-N-(1H-indazol-5-yl)-2-phenylacetamide;2-amino-2-(3-bromophenyl)-N-(1H-indazol-5-yl)acetamide;2-amino-2-(3-chlorophenyl)-N-(1H-indazol-5-yl)acetamide;2-amino-2-(4-chlorophenyl)-N-(1H-indazol-5-yl)acetamide;2-amino-2-(3,4-dichlorophenyl)-N-(1H-indazol-5-yl)acetamide;(2R)-2-amino-N-(1H-indazol-5-yl)-2-phenylacetamide;(2S)-2-amino-N-(1H-indazol-5-yl)-2-phenylacetamide;2-amino-N-(1H-indazol-5-yl)-2-[3-(trifluoromethyl)phenyl]acetamide
CID 159786778
4-amino-2-(3-aminophenyl)-N-(1H-indazol-5-yl)butanamide;4-amino-2-[3,5-bis(trifluoromethyl)phenyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3-chloro-2,6-difluorophenyl)-N-(1H-indazol-5-yl)butanamide;4-amino-2-(2,3-dichlorophenyl)-N-(1H-indazol-5-yl)butanamide;4-amino-N-(1H-indazol-5-yl)-2-(3-methylsulfanylphenyl)butanamide;4-amino-N-(1H-indazol-5-yl)-2-[3-(trifluoromethyl)phenyl]butanamide
CID 160189572
4-amino-2-(3-chloro-2-fluorophenyl)-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3-chlorophenyl)-N-(1H-indazol-5-yl)butanamide;3-amino-2-(3-chlorophenyl)-N-(1H-indazol-5-yl)propanamide;3-amino-2-(3,4-dichlorophenyl)-N-(1H-indazol-5-yl)propanamide;4-amino-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(1H-indazol-5-yl)butanamide;4-amino-N-(1H-indazol-5-yl)-2-naphthalen-2-ylbutanamide;4-amino-N-(1H-indazol-5-yl)-2-phenylbutanamide
CID 160809793
1-(3,4-dichlorophenyl)-N-[1-(3-methylphenyl)ethyl]indazole-4-carboxamide;1-(3,4-dichlorophenyl)-N-[(2-methylphenyl)methyl]indazole-4-carboxamide;1-(3,4-dichlorophenyl)-N-[(3-methylphenyl)methyl]indazole-4-carboxamide;1-(2-methylphenyl)-N-[[3-(trifluoromethyl)phenyl]methyl]indazole-4-carboxamide;1-(3-methylphenyl)-N-[[3-(trifluoromethyl)phenyl]methyl]indazole-4-carboxamide
CID 161455296
2-[2-(benzylamino)ethylamino]-2-(3-chlorophenyl)-N-(1H-indazol-5-yl)acetamide;2-(3-chlorophenyl)-2-[2-(ethylamino)ethylamino]-N-(1H-indazol-5-yl)acetamide;2-(3-chlorophenyl)-N-(1H-indazol-5-yl)-2-[3-(methylamino)propylamino]acetamide;2-(3-chlorophenyl)-N-(1H-indazol-5-yl)-2-(2-pyridin-2-ylethylamino)acetamide;2-(3-chlorophenyl)-N-(1H-indazol-5-yl)-2-(pyridin-2-ylmethylamino)acetamide
CID 158172515
2-amino-2-(3-chloro-4-fluorophenyl)-N-(1H-indazol-5-yl)acetamide;2-(2-aminoethylamino)-2-(3-chlorophenyl)-N-(1H-indazol-5-yl)acetamide;2-amino-N-(1H-indazol-5-yl)-2-(1H-indol-3-yl)acetamide;2-amino-N-(1H-indazol-5-yl)-2-naphthalen-2-ylacetamide;2-(3-aminopropylamino)-2-(3-chlorophenyl)-N-(1H-indazol-5-yl)acetamide;2-(3-chlorophenyl)-2-[2-(dimethylamino)ethylamino]-N-(1H-indazol-5-yl)acetamide;2-(3-chlorophenyl)-N-(1H-indazol-5-yl)-2-[2-(methylamino)ethylamino]acetamide
CID 158796398
4-amino-N-(3-bromo-2H-indazol-5-yl)-2-(3,4-dichlorophenyl)butanamide;4-amino-N-(3-chloro-2H-indazol-5-yl)-2-(3,4-dichlorophenyl)butanamide;4-amino-2-(6-chloro-2-pyridinyl)-N-(3-methyl-2H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(3-ethyl-2H-indazol-5-yl)butanamide;4-amino-2-(2,3-dichlorophenyl)-N-(3-methyl-2H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(3-methyl-2H-indazol-5-yl)butanamide
CID 158898413
N-[3-(4-acetylphenyl)-1H-indazol-5-yl]-4-amino-2-phenylbutanamide;4-amino-2-(3,4-dichlorophenyl)-N-[3-(3-fluorophenyl)-1H-indazol-5-yl]butanamide;4-amino-2-(3,4-dichlorophenyl)-N-[3-(3-methylphenyl)-1H-indazol-5-yl]butanamide;4-amino-N-[3-(4-methylphenyl)-1H-indazol-5-yl]-2-phenylbutanamide;3-[5-[(4-amino-2-phenylbutanoyl)amino]-1H-indazol-3-yl]benzamide
CID 160445436

Frequently Asked Questions

What is the IUPAC name of 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide?
The IUPAC name of 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide (CID 160786662) is 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide.
What is the SMILES notation for 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide?
The canonical SMILES for 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide is Cc1cc(NC(=O)C(CCN)c2ccc(Cl)c(Cl)c2)cc2cn[nH]c12.NCC(C(=O)Nc1cc(-c2ccccc2)c2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1.NCCC(C(=O)Nc1cc(-c2ccccc2)c2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1.NCCC(C(=O)Nc1cc(-c2ccccc2Cl)c2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1.NCCC(C(=O)Nc1ccc2[nH]ncc2c1)c1cc(C(F)(F)F)cc(Cl)n1.
What is the InChIKey of 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide?
The InChIKey is SBHKBVZJBPRANS-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H19Cl3N4O.C23H20Cl2N4O.C22H18Cl2N4O.C18H18Cl2N4O.C17H15ClF3N5O/c24-19-4-2-1-3-17(19)18-11-15(9-14-12-28-30-22(14)18)29-23(31)16(7-8-27)13-5-6-20(25)21(26)10-13;24-20-7-6-15(11-21(20)25)18(8-9-26)23(30)28-17-10-16-13-27-29-22(16)19(12-17)14-4-2-1-3-5-14;23-19-7-6-14(9-20(19)24)18(11-25)22(29)27-16-8-15-12-26-28-21(15)17(10-16)13-4-2-1-3-5-13;1-10-6-13(7-12-9-22-24-17(10)12)23-18(25)14(4-5-21)11-2-3-15(19)16(20)8-11;18-15-7-10(17(19,20)21)6-14(25-15)12(3-4-22)16(27)24-11-1-2-13-9(5-11)8-23-26-13/h1-6,9-12,16H,7-8,27H2,(H,28,30)(H,29,31);1-7,10-13,18H,8-9,26H2,(H,27,29)(H,28,30);1-10,12,18H,11,25H2,(H,26,28)(H,27,29);2-3,6-9,14H,4-5,21H2,1H3,(H,22,24)(H,23,25);1-2,5-8,12H,3-4,22H2,(H,23,26)(H,24,27).
What are the key properties of 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide?
4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide has a molecular weight of 2113.52 g/mol, XLogP of 25.04, 27 rotatable bonds, 15 hydrogen bond donors, and 16 hydrogen bond acceptors.
Where does this data come from?
All data for 4-amino-N-[7-(2-chlorophenyl)-1H-indazol-5-yl]-2-(3,4-dichlorophenyl)butanamide;4-amino-2-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-N-(1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-methyl-1H-indazol-5-yl)butanamide;4-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)butanamide;3-amino-2-(3,4-dichlorophenyl)-N-(7-phenyl-1H-indazol-5-yl)propanamide is sourced from PubChem (CID 160786662), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).