N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide

C170H131Cl6F8N19O16 — CID 160813090

About N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide

N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide (PubChem CID 160813090) has the molecular formula C170H131Cl6F8N19O16 and a molecular weight of 3060.74 g/mol. Its IUPAC name is N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide.

Molecular Properties

• Compound Name: N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide
• PubChem CID: 160813090
• Molecular Formula: C170H131Cl6F8N19O16
• Molecular Weight: 3060.74 g/mol
• Exact Mass: 3055.80
• IUPAC Name: N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide
• SMILES: Cc1cc2c(cc1-c1ccc(NC(=O)c3c(F)cccc3F)nc1)CCO2.Cc1cc2c(cc1-c1ccc(NC(=O)c3ccccc3Cl)nc1)C(C)(C)CO2.Cc1cc2c(cc1-c1cnc(NC(=O)c3c(F)cccc3F)cn1)C(C)(C)CO2.Cc1cc2c(cc1-c1cnc(NC(=O)c3ccccc3Cl)cn1)C(C)(C)CO2.Cc1cc2c(cc1-c1cnc(NC(=O)c3ccccc3F)cn1)C(C)(C)CO2.O=C(Nc1ccc(-c2cc3occc3cc2Cl)cn1)c1c(F)cccc1F.O=C(Nc1ccc(-c2cc3occc3cc2Cl)cn1)c1ccccc1Cl.O=C(Nc1ccc(-c2cc3occc3cc2Cl)cn1)c1ccccc1F
• InChI: InChI=1S/C23H21ClN2O2.C22H20ClN3O2.C22H19F2N3O2.C22H20FN3O2.C21H16F2N2O2.C20H12Cl2N2O2.C20H11ClF2N2O2.C20H12ClFN2O2/c1-14-10-20-18(23(2,3)13-28-20)11-17(14)15-8-9-21(25-12-15)26-22(27)16-6-4-5-7-19(16)24;1-13-8-19-16(22(2,3)12-28-19)9-15(13)18-10-25-20(11-24-18)26-21(27)14-6-4-5-7-17(14)23;1-12-7-18-14(22(2,3)11-29-18)8-13(12)17-9-26-19(10-25-17)27-21(28)20-15(23)5-4-6-16(20)24;1-13-8-19-16(22(2,3)12-28-19)9-15(13)18-10-25-20(11-24-18)26-21(27)14-6-4-5-7-17(14)23;1-12-9-18-13(7-8-27-18)10-15(12)14-5-6-19(24-11-14)25-21(26)20-16(22)3-2-4-17(20)23;21-16-4-2-1-3-14(16)20(25)24-19-6-5-13(11-23-19)15-10-18-12(7-8-26-18)9-17(15)22;21-14-8-11-6-7-27-17(11)9-13(14)12-4-5-18(24-10-12)25-20(26)19-15(22)2-1-3-16(19)23;21-16-9-12-7-8-26-18(12)10-15(16)13-5-6-19(23-11-13)24-20(25)14-3-1-2-4-17(14)22/h4-12H,13H2,1-3H3,(H,25,26,27);4-11H,12H2,1-3H3,(H,25,26,27);4-10H,11H2,1-3H3,(H,26,27,28);4-11H,12H2,1-3H3,(H,25,26,27);2-6,9-11H,7-8H2,1H3,(H,24,25,26);1-11H,(H,23,24,25);1-10H,(H,24,25,26);1-11H,(H,23,24,25)
• InChIKey: SEOAPOIUIAWWNL-UHFFFAOYSA-N
• XLogP: 41.62
• TPSA: 460.16 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 27
• Rotatable Bonds: 24
• Heavy Atoms: 219
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3060.74
LogP ≤ 5	41.62
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	27

Frequently Asked Questions

What is the IUPAC name of N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide?

The IUPAC name of N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide (CID 160813090) is N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide.

What is the SMILES notation for N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide?

The canonical SMILES for N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide is Cc1cc2c(cc1-c1ccc(NC(=O)c3c(F)cccc3F)nc1)CCO2.Cc1cc2c(cc1-c1ccc(NC(=O)c3ccccc3Cl)nc1)C(C)(C)CO2.Cc1cc2c(cc1-c1cnc(NC(=O)c3c(F)cccc3F)cn1)C(C)(C)CO2.Cc1cc2c(cc1-c1cnc(NC(=O)c3ccccc3Cl)cn1)C(C)(C)CO2.Cc1cc2c(cc1-c1cnc(NC(=O)c3ccccc3F)cn1)C(C)(C)CO2.O=C(Nc1ccc(-c2cc3occc3cc2Cl)cn1)c1c(F)cccc1F.O=C(Nc1ccc(-c2cc3occc3cc2Cl)cn1)c1ccccc1Cl.O=C(Nc1ccc(-c2cc3occc3cc2Cl)cn1)c1ccccc1F.

What is the InChIKey of N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide?

The InChIKey is SEOAPOIUIAWWNL-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H21ClN2O2.C22H20ClN3O2.C22H19F2N3O2.C22H20FN3O2.C21H16F2N2O2.C20H12Cl2N2O2.C20H11ClF2N2O2.C20H12ClFN2O2/c1-14-10-20-18(23(2,3)13-28-20)11-17(14)15-8-9-21(25-12-15)26-22(27)16-6-4-5-7-19(16)24;1-13-8-19-16(22(2,3)12-28-19)9-15(13)18-10-25-20(11-24-18)26-21(27)14-6-4-5-7-17(14)23;1-12-7-18-14(22(2,3)11-29-18)8-13(12)17-9-26-19(10-25-17)27-21(28)20-15(23)5-4-6-16(20)24;1-13-8-19-16(22(2,3)12-28-19)9-15(13)18-10-25-20(11-24-18)26-21(27)14-6-4-5-7-17(14)23;1-12-9-18-13(7-8-27-18)10-15(12)14-5-6-19(24-11-14)25-21(26)20-16(22)3-2-4-17(20)23;21-16-4-2-1-3-14(16)20(25)24-19-6-5-13(11-23-19)15-10-18-12(7-8-26-18)9-17(15)22;21-14-8-11-6-7-27-17(11)9-13(14)12-4-5-18(24-10-12)25-20(26)19-15(22)2-1-3-16(19)23;21-16-9-12-7-8-26-18(12)10-15(16)13-5-6-19(23-11-13)24-20(25)14-3-1-2-4-17(14)22/h4-12H,13H2,1-3H3,(H,25,26,27);4-11H,12H2,1-3H3,(H,25,26,27);4-10H,11H2,1-3H3,(H,26,27,28);4-11H,12H2,1-3H3,(H,25,26,27);2-6,9-11H,7-8H2,1H3,(H,24,25,26);1-11H,(H,23,24,25);1-10H,(H,24,25,26);1-11H,(H,23,24,25).

What are the key properties of N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide?

N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide has a molecular weight of 3060.74 g/mol, XLogP of 41.62, 24 rotatable bonds, 8 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]-2-fluorobenzamide;2-chloro-N-[5-(5-chloro-1-benzofuran-6-yl)-2-pyridinyl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(6-methyl-2,3-dihydro-1-benzofuran-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-fluoro-N-[5-(3,3,6-trimethyl-2H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide is sourced from PubChem (CID 160813090), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).