(2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol

C186H318F10N22O6 — CID 160842562

About (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol

(2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol (PubChem CID 160842562) has the molecular formula C186H318F10N22O6 and a molecular weight of 3148.72 g/mol. Its IUPAC name is (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol.

Molecular Properties

• Compound Name: (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol
• PubChem CID: 160842562
• Molecular Formula: C186H318F10N22O6
• Molecular Weight: 3148.72 g/mol
• Exact Mass: 3146.51
• IUPAC Name: (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol
• SMILES: CC(C)(C)N1CCC(C(F)F)CC1.CC(C)(C)N1CCC(F)(F)C[C@@H]1c1ccc(F)cc1.CC(C)(C)N1CCC(F)(F)C[C@H]1c1ccc(F)cc1.CC(C)(C)N1CCC2(CC1)COC2.CC(C)(C)N1CCCC[C@H]1CCO.CC(C)(O)[C@@H]1CCN(C(C)(C)C)[C@H](c2ccc(F)cc2)C1.CC(C)(O)[C@H]1CCN(C(C)(C)C)[C@@H](c2ccc(F)cc2)C1.CC(C)C.CC(C)[C@H]1CCN(C(C)(C)C)[C@@H](c2ccccc2)C1.C[C@@H]1CCN(C(C)(C)C)[C@H](c2ccn[nH]2)C1.C[C@H]1CCN(C(C)(C)C)C(c2ccn[nH]2)C1.Cc1noc(C2CCN(C(C)(C)C)CC2)n1.OCC[C@H]1CCCCN1.[C-]#[N+]C1(C)CCN(C(C)(C)C)CC1.[C-]#[N+]C1CCN(C(C)(C)C)CC1
• InChI: InChI=1S/2C18H28FNO.C18H29N.2C15H20F3N.2C13H23N3.C12H21N3O.C11H20N2.C11H21NO.C11H23NO.C10H19F2N.C10H18N2.C7H15NO.C4H10/c2*1-17(2,3)20-11-10-14(18(4,5)21)12-16(20)13-6-8-15(19)9-7-13;1-14(2)16-11-12-19(18(3,4)5)17(13-16)15-9-7-6-8-10-15;2*1-14(2,3)19-9-8-15(17,18)10-13(19)11-4-6-12(16)7-5-11;2*1-10-6-8-16(13(2,3)4)12(9-10)11-5-7-14-15-11;1-9-13-11(16-14-9)10-5-7-15(8-6-10)12(2,3)4;1-10(2,3)13-8-6-11(4,12-5)7-9-13;1-10(2,3)12-6-4-11(5-7-12)8-13-9-11;1-11(2,3)12-8-5-4-6-10(12)7-9-13;1-10(2,3)13-6-4-8(5-7-13)9(11)12;1-10(2,3)12-7-5-9(11-4)6-8-12;9-6-4-7-3-1-2-5-8-7;1-4(2)3/h2*6-9,14,16,21H,10-12H2,1-5H3;6-10,14,16-17H,11-13H2,1-5H3;2*4-7,13H,8-10H2,1-3H3;2*5,7,10,12H,6,8-9H2,1-4H3,(H,14,15);10H,5-8H2,1-4H3;6-9H2,1-4H3;4-9H2,1-3H3;10,13H,4-9H2,1-3H3;8-9H,4-7H2,1-3H3;9H,5-8H2,1-3H3;7-9H,1-6H2;4H,1-3H3/t2*14-,16+;16-,17+;2*13-;10-,12?;10-,12+;;;;10-;;;7-;/m1001001...0..1./s1
• InChIKey: SIFJCNFTSGXDTB-WUFLPXDZSA-N
• XLogP: 43.88
• TPSA: 249.30 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 24
• Rotatable Bonds: 16
• Heavy Atoms: 224
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3148.72
LogP ≤ 5	43.88
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	24

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Carbo_cation/anion', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol?

The IUPAC name of (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol (CID 160842562) is (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol.

What is the SMILES notation for (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol?

The canonical SMILES for (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol is CC(C)(C)N1CCC(C(F)F)CC1.CC(C)(C)N1CCC(F)(F)C[C@@H]1c1ccc(F)cc1.CC(C)(C)N1CCC(F)(F)C[C@H]1c1ccc(F)cc1.CC(C)(C)N1CCC2(CC1)COC2.CC(C)(C)N1CCCC[C@H]1CCO.CC(C)(O)[C@@H]1CCN(C(C)(C)C)[C@H](c2ccc(F)cc2)C1.CC(C)(O)[C@H]1CCN(C(C)(C)C)[C@@H](c2ccc(F)cc2)C1.CC(C)C.CC(C)[C@H]1CCN(C(C)(C)C)[C@@H](c2ccccc2)C1.C[C@@H]1CCN(C(C)(C)C)[C@H](c2ccn[nH]2)C1.C[C@H]1CCN(C(C)(C)C)C(c2ccn[nH]2)C1.Cc1noc(C2CCN(C(C)(C)C)CC2)n1.OCC[C@H]1CCCCN1.[C-]#[N+]C1(C)CCN(C(C)(C)C)CC1.[C-]#[N+]C1CCN(C(C)(C)C)CC1.

What is the InChIKey of (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol?

The InChIKey is SIFJCNFTSGXDTB-WUFLPXDZSA-N. The full InChI is InChI=1S/2C18H28FNO.C18H29N.2C15H20F3N.2C13H23N3.C12H21N3O.C11H20N2.C11H21NO.C11H23NO.C10H19F2N.C10H18N2.C7H15NO.C4H10/c2*1-17(2,3)20-11-10-14(18(4,5)21)12-16(20)13-6-8-15(19)9-7-13;1-14(2)16-11-12-19(18(3,4)5)17(13-16)15-9-7-6-8-10-15;2*1-14(2,3)19-9-8-15(17,18)10-13(19)11-4-6-12(16)7-5-11;2*1-10-6-8-16(13(2,3)4)12(9-10)11-5-7-14-15-11;1-9-13-11(16-14-9)10-5-7-15(8-6-10)12(2,3)4;1-10(2,3)13-8-6-11(4,12-5)7-9-13;1-10(2,3)12-6-4-11(5-7-12)8-13-9-11;1-11(2,3)12-8-5-4-6-10(12)7-9-13;1-10(2,3)13-6-4-8(5-7-13)9(11)12;1-10(2,3)12-7-5-9(11-4)6-8-12;9-6-4-7-3-1-2-5-8-7;1-4(2)3/h2*6-9,14,16,21H,10-12H2,1-5H3;6-10,14,16-17H,11-13H2,1-5H3;2*4-7,13H,8-10H2,1-3H3;2*5,7,10,12H,6,8-9H2,1-4H3,(H,14,15);10H,5-8H2,1-4H3;6-9H2,1-4H3;4-9H2,1-3H3;10,13H,4-9H2,1-3H3;8-9H,4-7H2,1-3H3;9H,5-8H2,1-3H3;7-9H,1-6H2;4H,1-3H3/t2*14-,16+;16-,17+;2*13-;10-,12?;10-,12+;;;;10-;;;7-;/m1001001...0..1./s1.

What are the key properties of (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol?

(2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol has a molecular weight of 3148.72 g/mol, XLogP of 43.88, 16 rotatable bonds, 7 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for (2R)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;(2S)-1-tert-butyl-4,4-difluoro-2-(4-fluorophenyl)piperidine;1-tert-butyl-4-(difluoromethyl)piperidine;2-[(2R,4S)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;2-[(2S,4R)-1-tert-butyl-2-(4-fluorophenyl)piperidin-4-yl]propan-2-ol;1-tert-butyl-4-isocyano-4-methylpiperidine;1-tert-butyl-4-isocyanopiperidine;(2S,4R)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;(4S)-1-tert-butyl-4-methyl-2-(1H-pyrazol-5-yl)piperidine;7-tert-butyl-2-oxa-7-azaspiro[3.5]nonane;(2R,4S)-1-tert-butyl-2-phenyl-4-propan-2-ylpiperidine;2-[(2S)-1-tert-butylpiperidin-2-yl]ethanol;5-(1-tert-butylpiperidin-4-yl)-3-methyl-1,2,4-oxadiazole;2-methylpropane;2-[(2R)-piperidin-2-yl]ethanol is sourced from PubChem (CID 160842562), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).