N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide

C123H163F3N18O13 — CID 160852531

About N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide

N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide (PubChem CID 160852531) has the molecular formula C123H163F3N18O13 and a molecular weight of 2158.76 g/mol. Its IUPAC name is N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide.

Molecular Properties

• Compound Name: N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide
• PubChem CID: 160852531
• Molecular Formula: C123H163F3N18O13
• Molecular Weight: 2158.76 g/mol
• Exact Mass: 2157.26
• IUPAC Name: N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide
• SMILES: CC(C)(C)C(=O)Nc1nc2ccc(C(C)(C)O)cc2n1C1CCC1.CC(C)(O)CC(=O)Nc1nc2ccc(C(C)(C)O)cc2n1C1CCC1.CC(C)(O)c1ccc2nc(NC(=O)C3CC3(C)C)n(C3CCC3)c2c1.CC(C)(O)c1ccc2nc(NC(=O)C3CC4(CCC4)C3)n(C3CCC3)c2c1.C[C@H](C(=O)Nc1nc2ccc(C(C)(C)O)cc2n1C1CCC1)C(C)(C)C.C[C@](O)(CC(=O)Nc1nc2ccc(C(F)(F)F)cc2n1C1CCC1)c1ccccc1
• InChI: InChI=1S/C22H22F3N3O2.C22H29N3O2.C21H31N3O2.C20H27N3O2.C19H27N3O3.C19H27N3O2/c1-21(30,14-6-3-2-4-7-14)13-19(29)27-20-26-17-11-10-15(22(23,24)25)12-18(17)28(20)16-8-5-9-16;1-21(2,27)15-7-8-17-18(11-15)25(16-5-3-6-16)20(23-17)24-19(26)14-12-22(13-14)9-4-10-22;1-13(20(2,3)4)18(25)23-19-22-16-11-10-14(21(5,6)26)12-17(16)24(19)15-8-7-9-15;1-19(2)11-14(19)17(24)22-18-21-15-9-8-12(20(3,4)25)10-16(15)23(18)13-6-5-7-13;1-18(2,24)11-16(23)21-17-20-14-9-8-12(19(3,4)25)10-15(14)22(17)13-6-5-7-13;1-18(2,3)16(23)21-17-20-14-10-9-12(19(4,5)24)11-15(14)22(17)13-7-6-8-13/h2-4,6-7,10-12,16,30H,5,8-9,13H2,1H3,(H,26,27,29);7-8,11,14,16,27H,3-6,9-10,12-13H2,1-2H3,(H,23,24,26);10-13,15,26H,7-9H2,1-6H3,(H,22,23,25);8-10,13-14,25H,5-7,11H2,1-4H3,(H,21,22,24);8-10,13,24-25H,5-7,11H2,1-4H3,(H,20,21,23);9-11,13,24H,6-8H2,1-5H3,(H,20,21,23)/t21-;;13-;;;/m0.1.../s1
• InChIKey: SJLFGZDZBBVZAG-SQWMEIBWSA-N
• XLogP: 25.17
• TPSA: 423.13 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 25
• Rotatable Bonds: 25
• Heavy Atoms: 157
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2158.76
LogP ≤ 5	25.17
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide?

The IUPAC name of N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide (CID 160852531) is N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide.

What is the SMILES notation for N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide?

The canonical SMILES for N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide is CC(C)(C)C(=O)Nc1nc2ccc(C(C)(C)O)cc2n1C1CCC1.CC(C)(O)CC(=O)Nc1nc2ccc(C(C)(C)O)cc2n1C1CCC1.CC(C)(O)c1ccc2nc(NC(=O)C3CC3(C)C)n(C3CCC3)c2c1.CC(C)(O)c1ccc2nc(NC(=O)C3CC4(CCC4)C3)n(C3CCC3)c2c1.C[C@H](C(=O)Nc1nc2ccc(C(C)(C)O)cc2n1C1CCC1)C(C)(C)C.C[C@](O)(CC(=O)Nc1nc2ccc(C(F)(F)F)cc2n1C1CCC1)c1ccccc1.

What is the InChIKey of N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide?

The InChIKey is SJLFGZDZBBVZAG-SQWMEIBWSA-N. The full InChI is InChI=1S/C22H22F3N3O2.C22H29N3O2.C21H31N3O2.C20H27N3O2.C19H27N3O3.C19H27N3O2/c1-21(30,14-6-3-2-4-7-14)13-19(29)27-20-26-17-11-10-15(22(23,24)25)12-18(17)28(20)16-8-5-9-16;1-21(2,27)15-7-8-17-18(11-15)25(16-5-3-6-16)20(23-17)24-19(26)14-12-22(13-14)9-4-10-22;1-13(20(2,3)4)18(25)23-19-22-16-11-10-14(21(5,6)26)12-17(16)24(19)15-8-7-9-15;1-19(2)11-14(19)17(24)22-18-21-15-9-8-12(20(3,4)25)10-16(15)23(18)13-6-5-7-13;1-18(2,24)11-16(23)21-17-20-14-9-8-12(19(3,4)25)10-15(14)22(17)13-6-5-7-13;1-18(2,3)16(23)21-17-20-14-10-9-12(19(4,5)24)11-15(14)22(17)13-7-6-8-13/h2-4,6-7,10-12,16,30H,5,8-9,13H2,1H3,(H,26,27,29);7-8,11,14,16,27H,3-6,9-10,12-13H2,1-2H3,(H,23,24,26);10-13,15,26H,7-9H2,1-6H3,(H,22,23,25);8-10,13-14,25H,5-7,11H2,1-4H3,(H,21,22,24);8-10,13,24-25H,5-7,11H2,1-4H3,(H,20,21,23);9-11,13,24H,6-8H2,1-5H3,(H,20,21,23)/t21-;;13-;;;/m0.1.../s1.

What are the key properties of N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide?

N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide has a molecular weight of 2158.76 g/mol, XLogP of 25.17, 25 rotatable bonds, 13 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylcyclopropane-1-carboxamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,2-dimethylpropanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-3-hydroxy-3-methylbutanamide;N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]spiro[3.3]heptane-2-carboxamide;(2S)-N-[1-cyclobutyl-6-(2-hydroxypropan-2-yl)benzimidazol-2-yl]-2,3,3-trimethylbutanamide;(3S)-N-[1-cyclobutyl-6-(trifluoromethyl)benzimidazol-2-yl]-3-hydroxy-3-phenylbutanamide is sourced from PubChem (CID 160852531), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).