N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine

C124H128N42O2S6 — CID 160853388

IUPACN-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine
SMILESCNCc1ccnc(Nc2nc3ccc(-c4cn[nH]c4C)nc3s2)c1.COC1CCN(Cc2ccnc(Nc3nc4ccc(-c5cn[nH]c5C)nc4s3)c2)C1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4CCCC4C)ccn3)sc2n1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4CCCCC4)ccn3)sc2n1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4CCOCC4)ccn3)sc2n1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4Cc5ccccc5C4)ccn3)sc2n1
InChIInChI=1S/C24H21N7S.C21H23N7OS.2C21H23N7S.C20H21N7OS.C17H17N7S/c1-15-19(11-26-30-15)20-6-7-21-23(27-20)32-24(28-21)29-22-10-16(8-9-25-22)12-31-13-17-4-2-3-5-18(17)14-31;1-13-16(10-23-27-13)17-3-4-18-20(24-17)30-21(25-18)26-19-9-14(5-7-22-19)11-28-8-6-15(12-28)29-2;1-13-4-3-9-28(13)12-15-7-8-22-19(10-15)26-21-25-18-6-5-17(24-20(18)29-21)16-11-23-27-14(16)2;1-14-16(12-23-27-14)17-5-6-18-20(24-17)29-21(25-18)26-19-11-15(7-8-22-19)13-28-9-3-2-4-10-28;1-13-15(11-22-26-13)16-2-3-17-19(23-16)29-20(24-17)25-18-10-14(4-5-21-18)12-27-6-8-28-9-7-27;1-10-12(9-20-24-10)13-3-4-14-16(21-13)25-17(22-14)23-15-7-11(8-18-2)5-6-19-15/h2-11H,12-14H2,1H3,(H,26,30)(H,25,28,29);3-5,7,9-10,15H,6,8,11-12H2,1-2H3,(H,23,27)(H,22,25,26);5-8,10-11,13H,3-4,9,12H2,1-2H3,(H,23,27)(H,22,25,26);5-8,11-12H,2-4,9-10,13H2,1H3,(H,23,27)(H,22,25,26);2-5,10-11H,6-9,12H2,1H3,(H,22,26)(H,21,24,25);3-7,9,18H,8H2,1-2H3,(H,20,24)(H,19,22,23)
InChIKeySJOAXJNPDIZIID-UHFFFAOYSA-N
MW2431.08 g/mol
LogP24.43
Rot. Bonds31

About N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine

N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine (PubChem CID 160853388) has the molecular formula C124H128N42O2S6 and a molecular weight of 2431.08 g/mol. Its IUPAC name is N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine.

Molecular Properties

Compound NameN-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine
PubChem CID160853388
Molecular FormulaC124H128N42O2S6
Molecular Weight2431.08 g/mol
Exact Mass2428.95
IUPAC NameN-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine
SMILESCNCc1ccnc(Nc2nc3ccc(-c4cn[nH]c4C)nc3s2)c1.COC1CCN(Cc2ccnc(Nc3nc4ccc(-c5cn[nH]c5C)nc4s3)c2)C1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4CCCC4C)ccn3)sc2n1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4CCCCC4)ccn3)sc2n1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4CCOCC4)ccn3)sc2n1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4Cc5ccccc5C4)ccn3)sc2n1
InChIInChI=1S/C24H21N7S.C21H23N7OS.2C21H23N7S.C20H21N7OS.C17H17N7S/c1-15-19(11-26-30-15)20-6-7-21-23(27-20)32-24(28-21)29-22-10-16(8-9-25-22)12-31-13-17-4-2-3-5-18(17)14-31;1-13-16(10-23-27-13)17-3-4-18-20(24-17)30-21(25-18)26-19-9-14(5-7-22-19)11-28-8-6-15(12-28)29-2;1-13-4-3-9-28(13)12-15-7-8-22-19(10-15)26-21-25-18-6-5-17(24-20(18)29-21)16-11-23-27-14(16)2;1-14-16(12-23-27-14)17-5-6-18-20(24-17)29-21(25-18)26-19-11-15(7-8-22-19)13-28-9-3-2-4-10-28;1-13-15(11-22-26-13)16-2-3-17-19(23-16)29-20(24-17)25-18-10-14(4-5-21-18)12-27-6-8-28-9-7-27;1-10-12(9-20-24-10)13-3-4-14-16(21-13)25-17(22-14)23-15-7-11(8-18-2)5-6-19-15/h2-11H,12-14H2,1H3,(H,26,30)(H,25,28,29);3-5,7,9-10,15H,6,8,11-12H2,1-2H3,(H,23,27)(H,22,25,26);5-8,10-11,13H,3-4,9,12H2,1-2H3,(H,23,27)(H,22,25,26);5-8,11-12H,2-4,9-10,13H2,1H3,(H,23,27)(H,22,25,26);2-5,10-11H,6-9,12H2,1H3,(H,22,26)(H,21,24,25);3-7,9,18H,8H2,1-2H3,(H,20,24)(H,19,22,23)
InChIKeySJOAXJNPDIZIID-UHFFFAOYSA-N
XLogP24.43
TPSA522.97 Ų
H-Bond Donors13
H-Bond Acceptors44
Rotatable Bonds31
Heavy Atoms174
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002431.08
LogP ≤ 524.43
H-Bond Donors ≤ 513
H-Bond Acceptors ≤ 1044

Analyze N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine with MolForge

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Launch Full Analysis

Related Compounds

N-[4-[4-(1-methoxypropan-2-yl)piperazin-1-yl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3S)-3-methyl-4-methylsulfonylpiperazin-1-yl]-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[4-(3,3,3-trifluoropropyl)piperazin-1-yl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 158157575
N-[4-[[(3R)-3-methoxypyrrolidin-1-yl]methyl]-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[[(3S)-3-methoxypyrrolidin-1-yl]methyl]-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(propan-2-yloxymethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(4-methylsulfonylpiperazin-1-yl)methyl]-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(propan-2-yloxymethyl)-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(1H-pyrazol-4-yl)-N-[4-[4-(3,3,3-trifluoropropyl)piperazin-1-yl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 159239916
N-[4-[[(3R)-3-methoxypyrrolidin-1-yl]methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[[(2S)-2-methylpyrrolidin-1-yl]methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[[(2R)-2-methylpyrrolidin-1-yl]methyl]-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[[(2S)-2-methylpyrrolidin-1-yl]methyl]-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]-2-pyridinyl]-5-(1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-pyridin-4-yl-N-[4-[4-(3,3,3-trifluoropropyl)piperazin-1-yl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 161552644
N-[4-[[(3R)-3-methoxypyrrolidin-1-yl]methyl]-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(propan-2-yloxymethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(propan-2-yloxymethyl)-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(4-propan-2-ylsulfonylpiperazin-1-yl)-2-pyridinyl]-5-(1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(4-propan-2-ylsulfonylpiperazin-1-yl)-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(1H-pyrazol-4-yl)-N-[4-[4-(3,3,3-trifluoropropyl)piperazin-1-yl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 163505270
5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[4-(3,3,3-trifluoropropyl)piperazin-1-yl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]-2-pyridinyl]-5-(1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]-2-pyridinyl]-5-pyridin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-pyridin-4-yl-N-[4-[4-(3,3,3-trifluoropropyl)piperazin-1-yl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 164058335
N-[4-[4-(1-methoxypropan-2-yl)piperazin-1-yl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 87944503
5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 87944601
N-[4-[4-(2-methoxyethyl)piperazin-1-yl]-2-pyridinyl]-5-pyridazin-4-yl-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 87944693
1-[[2-[[5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]amino]-4-pyridinyl]methyl]pyrrolidin-3-ol
CID 87945539
N-(4-morpholin-4-yl-2-pyridinyl)-5-(1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 87945541
1-[4-[2-[[5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]amino]-4-pyridinyl]piperazin-1-yl]-2-propan-2-yloxyethanone
CID 87945548
N-[4-[5-(2-methoxyethyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 87945551

Frequently Asked Questions

What is the IUPAC name of N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine?
The IUPAC name of N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine (CID 160853388) is N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine.
What is the SMILES notation for N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine?
The canonical SMILES for N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine is CNCc1ccnc(Nc2nc3ccc(-c4cn[nH]c4C)nc3s2)c1.COC1CCN(Cc2ccnc(Nc3nc4ccc(-c5cn[nH]c5C)nc4s3)c2)C1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4CCCC4C)ccn3)sc2n1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4CCCCC4)ccn3)sc2n1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4CCOCC4)ccn3)sc2n1.Cc1[nH]ncc1-c1ccc2nc(Nc3cc(CN4Cc5ccccc5C4)ccn3)sc2n1.
What is the InChIKey of N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine?
The InChIKey is SJOAXJNPDIZIID-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H21N7S.C21H23N7OS.2C21H23N7S.C20H21N7OS.C17H17N7S/c1-15-19(11-26-30-15)20-6-7-21-23(27-20)32-24(28-21)29-22-10-16(8-9-25-22)12-31-13-17-4-2-3-5-18(17)14-31;1-13-16(10-23-27-13)17-3-4-18-20(24-17)30-21(25-18)26-19-9-14(5-7-22-19)11-28-8-6-15(12-28)29-2;1-13-4-3-9-28(13)12-15-7-8-22-19(10-15)26-21-25-18-6-5-17(24-20(18)29-21)16-11-23-27-14(16)2;1-14-16(12-23-27-14)17-5-6-18-20(24-17)29-21(25-18)26-19-11-15(7-8-22-19)13-28-9-3-2-4-10-28;1-13-15(11-22-26-13)16-2-3-17-19(23-16)29-20(24-17)25-18-10-14(4-5-21-18)12-27-6-8-28-9-7-27;1-10-12(9-20-24-10)13-3-4-14-16(21-13)25-17(22-14)23-15-7-11(8-18-2)5-6-19-15/h2-11H,12-14H2,1H3,(H,26,30)(H,25,28,29);3-5,7,9-10,15H,6,8,11-12H2,1-2H3,(H,23,27)(H,22,25,26);5-8,10-11,13H,3-4,9,12H2,1-2H3,(H,23,27)(H,22,25,26);5-8,11-12H,2-4,9-10,13H2,1H3,(H,23,27)(H,22,25,26);2-5,10-11H,6-9,12H2,1H3,(H,22,26)(H,21,24,25);3-7,9,18H,8H2,1-2H3,(H,20,24)(H,19,22,23).
What are the key properties of N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine?
N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine has a molecular weight of 2431.08 g/mol, XLogP of 24.43, 31 rotatable bonds, 13 hydrogen bond donors, and 44 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(1,3-dihydroisoindol-2-ylmethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-[(3-methoxypyrrolidin-1-yl)methyl]-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;N-[4-(methylaminomethyl)-2-pyridinyl]-5-(5-methyl-1H-pyrazol-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-[(2-methylpyrrolidin-1-yl)methyl]-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(morpholin-4-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine;5-(5-methyl-1H-pyrazol-4-yl)-N-[4-(piperidin-1-ylmethyl)-2-pyridinyl]-[1,3]thiazolo[5,4-b]pyridin-2-amine is sourced from PubChem (CID 160853388), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).