5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole

C93H102F10N14S7 — CID 160857421

About 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole

5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole (PubChem CID 160857421) has the molecular formula C93H102F10N14S7 and a molecular weight of 1830.39 g/mol. Its IUPAC name is 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole.

Molecular Properties

• Compound Name: 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole
• PubChem CID: 160857421
• Molecular Formula: C93H102F10N14S7
• Molecular Weight: 1830.39 g/mol
• Exact Mass: 1828.63
• IUPAC Name: 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole
• SMILES: Cc1nc(-c2cccnc2)sc1C(C)C(C)C.Cc1nc(-c2cccnc2)sc1C(C)C(F)(F)F.Cc1nc(-c2cccnc2)sc1C(C)C1CC1.Cc1nc(-c2cncc(F)c2)sc1C(C)(C)C.Cc1nc(-c2cncc(F)c2)sc1C(C)C(C)C.Cc1nc(-c2cncc(F)c2)sc1C(C)C(F)(F)F.Cc1nc(-c2cncc(F)c2)sc1C(C)C1CC1
• InChI: InChI=1S/C14H15FN2S.C14H17FN2S.C14H16N2S.C14H18N2S.C13H15FN2S.C12H10F4N2S.C12H11F3N2S/c1-8(10-3-4-10)13-9(2)17-14(18-13)11-5-12(15)7-16-6-11;1-8(2)9(3)13-10(4)17-14(18-13)11-5-12(15)7-16-6-11;1-9(11-5-6-11)13-10(2)16-14(17-13)12-4-3-7-15-8-12;1-9(2)10(3)13-11(4)16-14(17-13)12-6-5-7-15-8-12;1-8-11(13(2,3)4)17-12(16-8)9-5-10(14)7-15-6-9;1-6(12(14,15)16)10-7(2)18-11(19-10)8-3-9(13)5-17-4-8;1-7(12(13,14)15)10-8(2)17-11(18-10)9-4-3-5-16-6-9/h5-8,10H,3-4H2,1-2H3;5-9H,1-4H3;3-4,7-9,11H,5-6H2,1-2H3;5-10H,1-4H3;5-7H,1-4H3;3-6H,1-2H3;3-7H,1-2H3
• InChIKey: SKAQZYQBIOQFMS-UHFFFAOYSA-N
• XLogP: 29.33
• TPSA: 180.46 Ų
• H-Bond Acceptors: 21
• Rotatable Bonds: 17
• Heavy Atoms: 124
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1830.39
LogP ≤ 5	29.33
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	21

Frequently Asked Questions

What is the IUPAC name of 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole?

The IUPAC name of 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole (CID 160857421) is 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole.

What is the SMILES notation for 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole?

The canonical SMILES for 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole is Cc1nc(-c2cccnc2)sc1C(C)C(C)C.Cc1nc(-c2cccnc2)sc1C(C)C(F)(F)F.Cc1nc(-c2cccnc2)sc1C(C)C1CC1.Cc1nc(-c2cncc(F)c2)sc1C(C)(C)C.Cc1nc(-c2cncc(F)c2)sc1C(C)C(C)C.Cc1nc(-c2cncc(F)c2)sc1C(C)C(F)(F)F.Cc1nc(-c2cncc(F)c2)sc1C(C)C1CC1.

What is the InChIKey of 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole?

The InChIKey is SKAQZYQBIOQFMS-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H15FN2S.C14H17FN2S.C14H16N2S.C14H18N2S.C13H15FN2S.C12H10F4N2S.C12H11F3N2S/c1-8(10-3-4-10)13-9(2)17-14(18-13)11-5-12(15)7-16-6-11;1-8(2)9(3)13-10(4)17-14(18-13)11-5-12(15)7-16-6-11;1-9(11-5-6-11)13-10(2)16-14(17-13)12-4-3-7-15-8-12;1-9(2)10(3)13-11(4)16-14(17-13)12-6-5-7-15-8-12;1-8-11(13(2,3)4)17-12(16-8)9-5-10(14)7-15-6-9;1-6(12(14,15)16)10-7(2)18-11(19-10)8-3-9(13)5-17-4-8;1-7(12(13,14)15)10-8(2)17-11(18-10)9-4-3-5-16-6-9/h5-8,10H,3-4H2,1-2H3;5-9H,1-4H3;3-4,7-9,11H,5-6H2,1-2H3;5-10H,1-4H3;5-7H,1-4H3;3-6H,1-2H3;3-7H,1-2H3.

What are the key properties of 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole?

5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole has a molecular weight of 1830.39 g/mol, XLogP of 29.33, 17 rotatable bonds, 0 hydrogen bond donors, and 21 hydrogen bond acceptors.

Where does this data come from?

All data for 5-tert-butyl-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-2-(5-fluoro-3-pyridinyl)-4-methyl-1,3-thiazole;5-(1-cyclopropylethyl)-4-methyl-2-pyridin-3-yl-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(3-methylbutan-2-yl)-1,3-thiazole;2-(5-fluoro-3-pyridinyl)-4-methyl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole;4-methyl-5-(3-methylbutan-2-yl)-2-pyridin-3-yl-1,3-thiazole;4-methyl-2-pyridin-3-yl-5-(1,1,1-trifluoropropan-2-yl)-1,3-thiazole is sourced from PubChem (CID 160857421), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).