4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol

C77H60Cl6N32O7S2 — CID 160862307

IUPAC4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol
SMILESCc1nc(-c2nc(N)cnc2-c2ccc(O)c(Cl)c2)n[nH]1.Cc1nc(-c2nc(N)cnc2-c2ccc(O)c(Cl)c2)sc1C.Cn1cnc(-c2nc(N)cnc2-c2ccc(O)c(Cl)c2)n1.Nc1cnc(-c2ccc(O)c(Cl)c2)c(-c2ncn[nH]2)n1.Nc1cnc(-c2ccc(O)c(Cl)c2)c(-c2nnco2)n1.Nc1cnc(-c2ccc(O)c(Cl)c2)c(-c2nncs2)n1
InChIInChI=1S/C15H13ClN4OS.2C13H11ClN6O.C12H9ClN6O.C12H8ClN5O2.C12H8ClN5OS/c1-7-8(2)22-15(19-7)14-13(18-6-12(17)20-14)9-3-4-11(21)10(16)5-9;1-20-6-17-13(19-20)12-11(16-5-10(15)18-12)7-2-3-9(21)8(14)4-7;1-6-17-13(20-19-6)12-11(16-5-10(15)18-12)7-2-3-9(21)8(14)4-7;13-7-3-6(1-2-8(7)20)10-11(12-16-5-17-19-12)18-9(14)4-15-10;2*13-7-3-6(1-2-8(7)19)10-11(12-18-16-5-20-12)17-9(14)4-15-10/h3-6,21H,1-2H3,(H2,17,20);2-6,21H,1H3,(H2,15,18);2-5,21H,1H3,(H2,15,18)(H,17,19,20);1-5,20H,(H2,14,18)(H,16,17,19);2*1-5,19H,(H2,14,17)
InChIKeySKQMQCNORLFCQG-UHFFFAOYSA-N
MW1822.40 g/mol
LogP14.49
Rot. Bonds12

About 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol

4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol (PubChem CID 160862307) has the molecular formula C77H60Cl6N32O7S2 and a molecular weight of 1822.40 g/mol. Its IUPAC name is 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol.

Molecular Properties

Compound Name4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol
PubChem CID160862307
Molecular FormulaC77H60Cl6N32O7S2
Molecular Weight1822.40 g/mol
Exact Mass1818.29
IUPAC Name4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol
SMILESCc1nc(-c2nc(N)cnc2-c2ccc(O)c(Cl)c2)n[nH]1.Cc1nc(-c2nc(N)cnc2-c2ccc(O)c(Cl)c2)sc1C.Cn1cnc(-c2nc(N)cnc2-c2ccc(O)c(Cl)c2)n1.Nc1cnc(-c2ccc(O)c(Cl)c2)c(-c2ncn[nH]2)n1.Nc1cnc(-c2ccc(O)c(Cl)c2)c(-c2nnco2)n1.Nc1cnc(-c2ccc(O)c(Cl)c2)c(-c2nncs2)n1
InChIInChI=1S/C15H13ClN4OS.2C13H11ClN6O.C12H9ClN6O.C12H8ClN5O2.C12H8ClN5OS/c1-7-8(2)22-15(19-7)14-13(18-6-12(17)20-14)9-3-4-11(21)10(16)5-9;1-20-6-17-13(19-20)12-11(16-5-10(15)18-12)7-2-3-9(21)8(14)4-7;1-6-17-13(20-19-6)12-11(16-5-10(15)18-12)7-2-3-9(21)8(14)4-7;13-7-3-6(1-2-8(7)20)10-11(12-16-5-17-19-12)18-9(14)4-15-10;2*13-7-3-6(1-2-8(7)19)10-11(12-18-16-5-20-12)17-9(14)4-15-10/h3-6,21H,1-2H3,(H2,17,20);2-6,21H,1H3,(H2,15,18);2-5,21H,1H3,(H2,15,18)(H,17,19,20);1-5,20H,(H2,14,18)(H,16,17,19);2*1-5,19H,(H2,14,17)
InChIKeySKQMQCNORLFCQG-UHFFFAOYSA-N
XLogP14.49
TPSA623.62 Ų
H-Bond Donors14
H-Bond Acceptors39
Rotatable Bonds12
Heavy Atoms124
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001822.40
LogP ≤ 514.49
H-Bond Donors ≤ 514
H-Bond Acceptors ≤ 1039

Analyze 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

4-[5-Amino-3-(1,4-dimethylimidazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methylimidazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(4-methyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(4-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol
CID 158257609
4-[5-amino-3-(2-chlorophenyl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(3-fluorophenyl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(4-fluorophenyl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(2H-tetrazol-5-yl)pyrazin-2-yl]-2-chlorophenol
CID 160718466
4-[5-Amino-3-(3,4-dimethylfuran-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(4,5-dimethylthiophen-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(4-methyl-1,3-thiazol-5-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(3-methylthiophen-2-yl)pyrazin-2-yl]-2-chlorophenol;4-(5-amino-3-pyrimidin-5-ylpyrazin-2-yl)-2-chlorophenol;4-(5-amino-3-thiophen-2-ylpyrazin-2-yl)-2-chlorophenol
CID 161033252

Frequently Asked Questions

What is the IUPAC name of 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol?
The IUPAC name of 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol (CID 160862307) is 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol.
What is the SMILES notation for 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol?
The canonical SMILES for 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol is Cc1nc(-c2nc(N)cnc2-c2ccc(O)c(Cl)c2)n[nH]1.Cc1nc(-c2nc(N)cnc2-c2ccc(O)c(Cl)c2)sc1C.Cn1cnc(-c2nc(N)cnc2-c2ccc(O)c(Cl)c2)n1.Nc1cnc(-c2ccc(O)c(Cl)c2)c(-c2ncn[nH]2)n1.Nc1cnc(-c2ccc(O)c(Cl)c2)c(-c2nnco2)n1.Nc1cnc(-c2ccc(O)c(Cl)c2)c(-c2nncs2)n1.
What is the InChIKey of 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol?
The InChIKey is SKQMQCNORLFCQG-UHFFFAOYSA-N. The full InChI is InChI=1S/C15H13ClN4OS.2C13H11ClN6O.C12H9ClN6O.C12H8ClN5O2.C12H8ClN5OS/c1-7-8(2)22-15(19-7)14-13(18-6-12(17)20-14)9-3-4-11(21)10(16)5-9;1-20-6-17-13(19-20)12-11(16-5-10(15)18-12)7-2-3-9(21)8(14)4-7;1-6-17-13(20-19-6)12-11(16-5-10(15)18-12)7-2-3-9(21)8(14)4-7;13-7-3-6(1-2-8(7)20)10-11(12-16-5-17-19-12)18-9(14)4-15-10;2*13-7-3-6(1-2-8(7)19)10-11(12-18-16-5-20-12)17-9(14)4-15-10/h3-6,21H,1-2H3,(H2,17,20);2-6,21H,1H3,(H2,15,18);2-5,21H,1H3,(H2,15,18)(H,17,19,20);1-5,20H,(H2,14,18)(H,16,17,19);2*1-5,19H,(H2,14,17).
What are the key properties of 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol?
4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol has a molecular weight of 1822.40 g/mol, XLogP of 14.49, 12 rotatable bonds, 14 hydrogen bond donors, and 39 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[5-amino-3-(4,5-dimethyl-1,3-thiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1-methyl-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(5-methyl-1H-1,2,4-triazol-3-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1,3,4-thiadiazol-2-yl)pyrazin-2-yl]-2-chlorophenol;4-[5-amino-3-(1H-1,2,4-triazol-5-yl)pyrazin-2-yl]-2-chlorophenol is sourced from PubChem (CID 160862307), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).