N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide

C189H277N35O15S7 — CID 160872191

IUPACN-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide
SMILESCCC(=O)N1CCCCC1CN1CCN(C(=O)Nc2nc(-c3cc(C4CCCCC4)ccc3OC)cs2)CC1.CCCOc1ccc(CC)cc1-c1csc(NC(=O)N2CCN(CC3CCCN(C)C3)CC2)n1.CCCc1ccc(OCC)c(-c2csc(NC(=O)N3CCN(CC4CCCN(C)C4)CC3)n2)c1.CCOc1ccc(C2CCCC2)cc1-c1csc(NC(=O)N2CCN(C[C@@H]3CCCN(C)C3)CC2)n1.CCc1ccc(OC)c(-c2csc(NC(=O)N3CCN(CC4CCCN(C)C4)CC3)n2)c1.COc1ccc(C2CCCCC2)cc1-c1csc(NC(=O)N2CCN(CC3CCCCN3)CC2)n1.COc1ccc(C2CCCCC2)cc1-c1csc(NC(=O)N2CCN(CC3CCCCN3C)CC2)n1
InChIInChI=1S/C30H43N5O3S.2C28H41N5O2S.C27H39N5O2S.2C26H39N5O2S.C24H35N5O2S/c1-3-28(36)35-14-8-7-11-24(35)20-33-15-17-34(18-16-33)30(37)32-29-31-26(21-39-29)25-19-23(12-13-27(25)38-2)22-9-5-4-6-10-22;1-31-13-7-6-10-23(31)19-32-14-16-33(17-15-32)28(34)30-27-29-25(20-36-27)24-18-22(11-12-26(24)35-2)21-8-4-3-5-9-21;1-3-35-26-11-10-23(22-8-4-5-9-22)17-24(26)25-20-36-27(29-25)30-28(34)33-15-13-32(14-16-33)19-21-7-6-12-31(2)18-21;1-34-25-11-10-21(20-7-3-2-4-8-20)17-23(25)24-19-35-26(29-24)30-27(33)32-15-13-31(14-16-32)18-22-9-5-6-12-28-22;1-4-15-33-24-9-8-20(5-2)16-22(24)23-19-34-25(27-23)28-26(32)31-13-11-30(12-14-31)18-21-7-6-10-29(3)17-21;1-4-7-20-9-10-24(33-5-2)22(16-20)23-19-34-25(27-23)28-26(32)31-14-12-30(13-15-31)18-21-8-6-11-29(3)17-21;1-4-18-7-8-22(31-3)20(14-18)21-17-32-23(25-21)26-24(30)29-12-10-28(11-13-29)16-19-6-5-9-27(2)15-19/h12-13,19,21-22,24H,3-11,14-18,20H2,1-2H3,(H,31,32,37);11-12,18,20-21,23H,3-10,13-17,19H2,1-2H3,(H,29,30,34);10-11,17,20-22H,3-9,12-16,18-19H2,1-2H3,(H,29,30,34);10-11,17,19-20,22,28H,2-9,12-16,18H2,1H3,(H,29,30,33);8-9,16,19,21H,4-7,10-15,17-18H2,1-3H3,(H,27,28,32);9-10,16,19,21H,4-8,11-15,17-18H2,1-3H3,(H,27,28,32);7-8,14,17,19H,4-6,9-13,15-16H2,1-3H3,(H,25,26,30)/t;;21-;;;;/m..1..../s1
InChIKeySLXAMHCQWUKRSA-IVHOQCKQSA-N
MW3503.99 g/mol
LogP35.00
Rot. Bonds48

About N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide

N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide (PubChem CID 160872191) has the molecular formula C189H277N35O15S7 and a molecular weight of 3503.99 g/mol. Its IUPAC name is N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide.

Molecular Properties

Compound NameN-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide
PubChem CID160872191
Molecular FormulaC189H277N35O15S7
Molecular Weight3503.99 g/mol
Exact Mass3501.00
IUPAC NameN-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide
SMILESCCC(=O)N1CCCCC1CN1CCN(C(=O)Nc2nc(-c3cc(C4CCCCC4)ccc3OC)cs2)CC1.CCCOc1ccc(CC)cc1-c1csc(NC(=O)N2CCN(CC3CCCN(C)C3)CC2)n1.CCCc1ccc(OCC)c(-c2csc(NC(=O)N3CCN(CC4CCCN(C)C4)CC3)n2)c1.CCOc1ccc(C2CCCC2)cc1-c1csc(NC(=O)N2CCN(C[C@@H]3CCCN(C)C3)CC2)n1.CCc1ccc(OC)c(-c2csc(NC(=O)N3CCN(CC4CCCN(C)C4)CC3)n2)c1.COc1ccc(C2CCCCC2)cc1-c1csc(NC(=O)N2CCN(CC3CCCCN3)CC2)n1.COc1ccc(C2CCCCC2)cc1-c1csc(NC(=O)N2CCN(CC3CCCCN3C)CC2)n1
InChIInChI=1S/C30H43N5O3S.2C28H41N5O2S.C27H39N5O2S.2C26H39N5O2S.C24H35N5O2S/c1-3-28(36)35-14-8-7-11-24(35)20-33-15-17-34(18-16-33)30(37)32-29-31-26(21-39-29)25-19-23(12-13-27(25)38-2)22-9-5-4-6-10-22;1-31-13-7-6-10-23(31)19-32-14-16-33(17-15-32)28(34)30-27-29-25(20-36-27)24-18-22(11-12-26(24)35-2)21-8-4-3-5-9-21;1-3-35-26-11-10-23(22-8-4-5-9-22)17-24(26)25-20-36-27(29-25)30-28(34)33-15-13-32(14-16-33)19-21-7-6-12-31(2)18-21;1-34-25-11-10-21(20-7-3-2-4-8-20)17-23(25)24-19-35-26(29-24)30-27(33)32-15-13-31(14-16-32)18-22-9-5-6-12-28-22;1-4-15-33-24-9-8-20(5-2)16-22(24)23-19-34-25(27-23)28-26(32)31-13-11-30(12-14-31)18-21-7-6-10-29(3)17-21;1-4-7-20-9-10-24(33-5-2)22(16-20)23-19-34-25(27-23)28-26(32)31-14-12-30(13-15-31)18-21-8-6-11-29(3)17-21;1-4-18-7-8-22(31-3)20(14-18)21-17-32-23(25-21)26-24(30)29-12-10-28(11-13-29)16-19-6-5-9-27(2)15-19/h12-13,19,21-22,24H,3-11,14-18,20H2,1-2H3,(H,31,32,37);11-12,18,20-21,23H,3-10,13-17,19H2,1-2H3,(H,29,30,34);10-11,17,20-22H,3-9,12-16,18-19H2,1-2H3,(H,29,30,34);10-11,17,19-20,22,28H,2-9,12-16,18H2,1H3,(H,29,30,33);8-9,16,19,21H,4-7,10-15,17-18H2,1-3H3,(H,27,28,32);9-10,16,19,21H,4-8,11-15,17-18H2,1-3H3,(H,27,28,32);7-8,14,17,19H,4-6,9-13,15-16H2,1-3H3,(H,25,26,30)/t;;21-;;;;/m..1..../s1
InChIKeySLXAMHCQWUKRSA-IVHOQCKQSA-N
XLogP35.00
TPSA452.44 Ų
H-Bond Donors8
H-Bond Acceptors42
Rotatable Bonds48
Heavy Atoms246
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003503.99
LogP ≤ 535.00
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1042

Analyze N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[4-(5-butyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-4-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-4-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-5-fluoro-1,3-thiazol-2-yl]-4-(2-piperidin-1-ylethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-5-fluoro-1,3-thiazol-2-yl]-4-(2-pyrrolidin-1-ylethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-4-yl)methyl]piperazine-1-carboxamide;N-[4-[2-methoxy-5-(1,1,2,2,2-pentafluoroethyl)phenyl]-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-4-yl)methyl]piperazine-1-carboxamide
CID 157965907
4-(2-cyclohexyl-2-oxoethyl)-N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]piperazine-1-carboxamide;4-(2-cyclopentylethyl)-N-[4-[2-methoxy-5-(1,1,2,2,2-pentafluoroethyl)phenyl]-1,3-thiazol-2-yl]piperazine-1-carboxamide;4-[2-[3-(ethylamino)cyclopentyl]ethyl]-N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]piperazine-1-carboxamide;4-[2-[3-(ethylamino)pyrrolidin-1-yl]ethyl]-N-[5-fluoro-4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]-1,4-diazepane-1-carboxamide;N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-(2-pyrrolidin-1-ylacetyl)-1,4-diazepane-1-carboxamide;N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-(2-pyrrolidin-1-ylethyl)piperazine-1-carboxamide
CID 161721236
N-[2-(4-acetylpiperazin-1-yl)phenyl]-2-(2,3-dihydro-1-benzofuran-5-yl)-1,3-thiazole-4-carboxamide;2-(2,3-dihydro-1-benzofuran-5-yl)-N-[2-(2-methylpiperazin-1-yl)phenyl]-1,3-thiazole-4-carboxamide;2-(2,3-dihydro-1-benzofuran-5-yl)-N-[2-(3-methylpiperazin-1-yl)phenyl]-1,3-thiazole-4-carboxamide;2-(2,3-dihydro-1-benzofuran-5-yl)-N-(2-piperidin-4-ylphenyl)-1,3-thiazole-4-carboxamide;2-(2,3-dihydro-1-benzofuran-5-yl)-N-[2-(1,2,3,6-tetrahydropyridin-4-yl)phenyl]-1,3-thiazole-4-carboxamide
CID 157105447
benzyl 2-[[4-[[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]carbamoyl]piperazin-1-yl]methyl]piperidine-1-carboxylate;N-[4-(5-butyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(1-methylpiperidine-2-carbonyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3S)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-methoxy-5-pentan-3-ylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide
CID 157847005
4-[3-(diethylamino)propyl]-N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]piperazine-1-carboxamide;4-[2-(dimethylamino)ethyl]-N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]piperazine-1-carboxamide;4-[3-[ethyl(methyl)amino]propyl]-N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]piperazine-1-carboxamide;N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-(3-piperidin-1-ylpropyl)-1,4-diazepane-1-carboxamide;N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-(3-piperidin-1-ylpropyl)piperazine-1-carboxamide;N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-(3-pyrrolidin-1-ylpropyl)-1,4-diazepane-1-carboxamide;N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-(3-pyrrolidin-1-ylpropyl)piperazine-1-carboxamide
CID 158366664
N-[4-(5-butyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-(2-pyrrolidin-1-ylethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-(2-pyrrolidin-1-ylethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-ethylphenyl)-1,3-thiazol-2-yl]-4-(2-pyrrolidin-1-ylethyl)piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-pyrrolidin-1-ylethyl)piperazine-1-carboxamide;N-[4-(5-hexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-pyrrolidin-1-ylethyl)piperazine-1-carboxamide
CID 159348342
N-[4-(5-butyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-butyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-(2-pyrrolidin-1-ylethyl)piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-4-yl)methyl]piperazine-1-carboxamide
CID 159574885
N-[4-(5-butyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-oxo-2-piperidin-1-ylethyl)piperazine-1-carboxamide;N-[4-(5-butyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-piperidin-1-ylethyl)piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-oxo-2-piperidin-1-ylethyl)piperazine-1-carboxamide;N-[5-(2-methoxy-5-propoxyphenyl)-3H-pyrrol-2-yl]-4-(2-oxo-2-piperidin-1-ylethyl)piperazine-1-carboxamide;N-[4-(2-methoxy-5-propoxyphenyl)-1,3-thiazol-2-yl]-4-(2-piperidin-1-ylethyl)piperazine-1-carboxamide;bis(N-[4-(2-methoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-(2-oxo-2-piperidin-1-ylethyl)piperazine-1-carboxamide)
CID 159584101
2-(2,3-dihydro-1-benzofuran-5-yl)-N-[2-[(3S)-3-methylpiperazin-1-yl]phenyl]-1,3-thiazole-4-carboxamide;2-(2,3-dihydro-1-benzofuran-5-yl)-N-[2-[(3R)-3-methylpiperazin-1-yl]phenyl]-1,3-thiazole-4-carboxamide;2-(2,3-dihydro-1-benzofuran-5-yl)-N-[2-(4-methylpiperazin-1-yl)phenyl]-1,3-thiazole-4-carboxamide;2-(2,3-dihydro-1-benzofuran-5-yl)-N-(3-piperazin-1-yl-2-pyridinyl)-1,3-thiazole-4-carboxamide;2-(2,3-dihydro-1-benzofuran-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide
CID 159894202

Frequently Asked Questions

What is the IUPAC name of N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide?
The IUPAC name of N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide (CID 160872191) is N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide.
What is the SMILES notation for N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide?
The canonical SMILES for N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide is CCC(=O)N1CCCCC1CN1CCN(C(=O)Nc2nc(-c3cc(C4CCCCC4)ccc3OC)cs2)CC1.CCCOc1ccc(CC)cc1-c1csc(NC(=O)N2CCN(CC3CCCN(C)C3)CC2)n1.CCCc1ccc(OCC)c(-c2csc(NC(=O)N3CCN(CC4CCCN(C)C4)CC3)n2)c1.CCOc1ccc(C2CCCC2)cc1-c1csc(NC(=O)N2CCN(C[C@@H]3CCCN(C)C3)CC2)n1.CCc1ccc(OC)c(-c2csc(NC(=O)N3CCN(CC4CCCN(C)C4)CC3)n2)c1.COc1ccc(C2CCCCC2)cc1-c1csc(NC(=O)N2CCN(CC3CCCCN3)CC2)n1.COc1ccc(C2CCCCC2)cc1-c1csc(NC(=O)N2CCN(CC3CCCCN3C)CC2)n1.
What is the InChIKey of N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide?
The InChIKey is SLXAMHCQWUKRSA-IVHOQCKQSA-N. The full InChI is InChI=1S/C30H43N5O3S.2C28H41N5O2S.C27H39N5O2S.2C26H39N5O2S.C24H35N5O2S/c1-3-28(36)35-14-8-7-11-24(35)20-33-15-17-34(18-16-33)30(37)32-29-31-26(21-39-29)25-19-23(12-13-27(25)38-2)22-9-5-4-6-10-22;1-31-13-7-6-10-23(31)19-32-14-16-33(17-15-32)28(34)30-27-29-25(20-36-27)24-18-22(11-12-26(24)35-2)21-8-4-3-5-9-21;1-3-35-26-11-10-23(22-8-4-5-9-22)17-24(26)25-20-36-27(29-25)30-28(34)33-15-13-32(14-16-33)19-21-7-6-12-31(2)18-21;1-34-25-11-10-21(20-7-3-2-4-8-20)17-23(25)24-19-35-26(29-24)30-27(33)32-15-13-31(14-16-32)18-22-9-5-6-12-28-22;1-4-15-33-24-9-8-20(5-2)16-22(24)23-19-34-25(27-23)28-26(32)31-13-11-30(12-14-31)18-21-7-6-10-29(3)17-21;1-4-7-20-9-10-24(33-5-2)22(16-20)23-19-34-25(27-23)28-26(32)31-14-12-30(13-15-31)18-21-8-6-11-29(3)17-21;1-4-18-7-8-22(31-3)20(14-18)21-17-32-23(25-21)26-24(30)29-12-10-28(11-13-29)16-19-6-5-9-27(2)15-19/h12-13,19,21-22,24H,3-11,14-18,20H2,1-2H3,(H,31,32,37);11-12,18,20-21,23H,3-10,13-17,19H2,1-2H3,(H,29,30,34);10-11,17,20-22H,3-9,12-16,18-19H2,1-2H3,(H,29,30,34);10-11,17,19-20,22,28H,2-9,12-16,18H2,1H3,(H,29,30,33);8-9,16,19,21H,4-7,10-15,17-18H2,1-3H3,(H,27,28,32);9-10,16,19,21H,4-8,11-15,17-18H2,1-3H3,(H,27,28,32);7-8,14,17,19H,4-6,9-13,15-16H2,1-3H3,(H,25,26,30)/t;;21-;;;;/m..1..../s1.
What are the key properties of N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide?
N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide has a molecular weight of 3503.99 g/mol, XLogP of 35.00, 48 rotatable bonds, 8 hydrogen bond donors, and 42 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-(piperidin-2-ylmethyl)piperazine-1-carboxamide;N-[4-(5-cyclohexyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-propanoylpiperidin-2-yl)methyl]piperazine-1-carboxamide;N-[4-(5-cyclopentyl-2-ethoxyphenyl)-1,3-thiazol-2-yl]-4-[[(3R)-1-methylpiperidin-3-yl]methyl]piperazine-1-carboxamide;N-[4-(2-ethoxy-5-propylphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide;N-[4-(5-ethyl-2-propoxyphenyl)-1,3-thiazol-2-yl]-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamide is sourced from PubChem (CID 160872191), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).