6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine

C80H60Cl3F10N25O4 — CID 160878994

IUPAC6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine
SMILESCCc1nc2ncc(Cl)cc2n1-c1cncc(Nc2ccc(OC(F)(F)F)cc2)n1.CCc1nc2ncc(Cl)cc2n1-c1cncc(Nc2ccc(OC(F)F)c(F)c2)n1.Cc1nc2ncc(Cl)cc2n1-c1cncc(Nc2ccccc2)n1.Cc1nc2ncc(Nc3ccc(OC(F)F)cc3)cc2n1-c1cncc(Nc2ccc(OC(F)F)cc2)n1
InChIInChI=1S/C25H19F4N7O2.2C19H14ClF3N6O.C17H13ClN6/c1-14-32-23-20(10-17(11-31-23)33-15-2-6-18(7-3-15)37-24(26)27)36(14)22-13-30-12-21(35-22)34-16-4-8-19(9-5-16)38-25(28)29;1-2-16-28-18-14(7-11(20)8-25-18)29(16)17-10-24-9-15(27-17)26-12-3-5-13(6-4-12)30-19(21,22)23;1-2-16-28-18-13(5-10(20)7-25-18)29(16)17-9-24-8-15(27-17)26-11-3-4-14(12(21)6-11)30-19(22)23;1-11-21-17-14(7-12(18)8-20-17)24(11)16-10-19-9-15(23-16)22-13-5-3-2-4-6-13/h2-13,24-25,33H,1H3,(H,34,35);3-10H,2H2,1H3,(H,26,27);3-9,19H,2H2,1H3,(H,26,27);2-10H,1H3,(H,22,23)
InChIKeySMTZVXLPCSODTE-UHFFFAOYSA-N
MW1731.87 g/mol
LogP20.10
Rot. Bonds23

About 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine

6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine (PubChem CID 160878994) has the molecular formula C80H60Cl3F10N25O4 and a molecular weight of 1731.87 g/mol. Its IUPAC name is 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine.

Molecular Properties

Compound Name6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine
PubChem CID160878994
Molecular FormulaC80H60Cl3F10N25O4
Molecular Weight1731.87 g/mol
Exact Mass1729.42
IUPAC Name6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine
SMILESCCc1nc2ncc(Cl)cc2n1-c1cncc(Nc2ccc(OC(F)(F)F)cc2)n1.CCc1nc2ncc(Cl)cc2n1-c1cncc(Nc2ccc(OC(F)F)c(F)c2)n1.Cc1nc2ncc(Cl)cc2n1-c1cncc(Nc2ccccc2)n1.Cc1nc2ncc(Nc3ccc(OC(F)F)cc3)cc2n1-c1cncc(Nc2ccc(OC(F)F)cc2)n1
InChIInChI=1S/C25H19F4N7O2.2C19H14ClF3N6O.C17H13ClN6/c1-14-32-23-20(10-17(11-31-23)33-15-2-6-18(7-3-15)37-24(26)27)36(14)22-13-30-12-21(35-22)34-16-4-8-19(9-5-16)38-25(28)29;1-2-16-28-18-14(7-11(20)8-25-18)29(16)17-10-24-9-15(27-17)26-12-3-5-13(6-4-12)30-19(21,22)23;1-2-16-28-18-13(5-10(20)7-25-18)29(16)17-9-24-8-15(27-17)26-11-3-4-14(12(21)6-11)30-19(22)23;1-11-21-17-14(7-12(18)8-20-17)24(11)16-10-19-9-15(23-16)22-13-5-3-2-4-6-13/h2-13,24-25,33H,1H3,(H,34,35);3-10H,2H2,1H3,(H,26,27);3-9,19H,2H2,1H3,(H,26,27);2-10H,1H3,(H,22,23)
InChIKeySMTZVXLPCSODTE-UHFFFAOYSA-N
XLogP20.10
TPSA323.03 Ų
H-Bond Donors5
H-Bond Acceptors29
Rotatable Bonds23
Heavy Atoms122
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001731.87
LogP ≤ 520.10
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1029

Analyze 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine with MolForge

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Related Compounds

2-[6-chloro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethoxy)phenyl]pyrimidin-4-amine
CID 74767185
2-[6-chloro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(difluoromethoxy)phenyl]pyrimidin-4-amine
CID 74767186
2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-4-N-[4-(difluoromethoxy)phenyl]-5-fluoropyrimidine-4,6-diamine
CID 90178402
6-(6-chloro-2-methylbenzimidazol-1-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine
CID 118094666
6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine
CID 118094786
1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine
CID 118094787
6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine
CID 118094810
6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine
CID 118094814
6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine
CID 118095001
6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine
CID 118095044
6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine
CID 118095120
6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-2-N-[4-(difluoromethoxy)-3-fluorophenyl]-1,3,5-triazine-2,4-diamine
CID 118095572

Frequently Asked Questions

What is the IUPAC name of 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine?
The IUPAC name of 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine (CID 160878994) is 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine.
What is the SMILES notation for 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine?
The canonical SMILES for 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine is CCc1nc2ncc(Cl)cc2n1-c1cncc(Nc2ccc(OC(F)(F)F)cc2)n1.CCc1nc2ncc(Cl)cc2n1-c1cncc(Nc2ccc(OC(F)F)c(F)c2)n1.Cc1nc2ncc(Cl)cc2n1-c1cncc(Nc2ccccc2)n1.Cc1nc2ncc(Nc3ccc(OC(F)F)cc3)cc2n1-c1cncc(Nc2ccc(OC(F)F)cc2)n1.
What is the InChIKey of 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine?
The InChIKey is SMTZVXLPCSODTE-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H19F4N7O2.2C19H14ClF3N6O.C17H13ClN6/c1-14-32-23-20(10-17(11-31-23)33-15-2-6-18(7-3-15)37-24(26)27)36(14)22-13-30-12-21(35-22)34-16-4-8-19(9-5-16)38-25(28)29;1-2-16-28-18-14(7-11(20)8-25-18)29(16)17-10-24-9-15(27-17)26-12-3-5-13(6-4-12)30-19(21,22)23;1-2-16-28-18-13(5-10(20)7-25-18)29(16)17-9-24-8-15(27-17)26-11-3-4-14(12(21)6-11)30-19(22)23;1-11-21-17-14(7-12(18)8-20-17)24(11)16-10-19-9-15(23-16)22-13-5-3-2-4-6-13/h2-13,24-25,33H,1H3,(H,34,35);3-10H,2H2,1H3,(H,26,27);3-9,19H,2H2,1H3,(H,26,27);2-10H,1H3,(H,22,23).
What are the key properties of 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine?
6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine has a molecular weight of 1731.87 g/mol, XLogP of 20.10, 23 rotatable bonds, 5 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;6-(6-chloro-2-ethylimidazo[4,5-b]pyridin-1-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-N-phenylpyrazin-2-amine;1-[6-[4-(difluoromethoxy)anilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)phenyl]-2-methylimidazo[4,5-b]pyridin-6-amine is sourced from PubChem (CID 160878994), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).