2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide

C151H129F8N31O7S4 — CID 160881624

IUPAC2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide
SMILESCc1ccc(CNC(=O)c2cc(C(F)(F)F)cnc2NCc2ccc(-c3ccc4ncc5ncn(C)c5c4c3)s2)cc1F.Cc1ccc([C@H](C)NC(=O)c2cc(C#N)cnc2N[C@@H](COc2ccc3c(c2)CC(=O)N3)c2ccccc2)cc1.Cc1ccc([C@H](C)NC(=O)c2cc(C(F)(F)F)cnc2NCc2ccc(-c3cc4c(N)ncnc4cn3)s2)cc1.Cc1ccc([C@H](C)NC(=O)c2cccnc2NCc2ccc(-c3ccc4ncc5ncn(C)c5c4c3)s2)cc1.Cc1ccc([C@H](C)n2cnc3ccnc(NCc4ccc(-c5ccc6ncnc(N)c6c5)s4)c3c2=O)cc1F
InChIInChI=1S/C32H29N5O3.C31H24F4N6OS.C31H28N6OS.C29H24FN7OS.C28H24F3N7OS/c1-20-8-10-23(11-9-20)21(2)35-32(39)27-14-22(17-33)18-34-31(27)37-29(24-6-4-3-5-7-24)19-40-26-12-13-28-25(15-26)16-30(38)36-28;1-17-3-4-18(9-24(17)32)12-39-30(42)23-11-20(31(33,34)35)13-37-29(23)38-14-21-6-8-27(43-21)19-5-7-25-22(10-19)28-26(15-36-25)40-16-41(28)2;1-19-6-8-21(9-7-19)20(2)36-31(38)24-5-4-14-32-30(24)34-16-23-11-13-28(39-23)22-10-12-26-25(15-22)29-27(17-33-26)35-18-37(29)3;1-16-3-4-18(12-22(16)30)17(2)37-15-36-24-9-10-32-28(26(24)29(37)38)33-13-20-6-8-25(39-20)19-5-7-23-21(11-19)27(31)35-14-34-23;1-15-3-5-17(6-4-15)16(2)38-27(39)21-9-18(28(29,30)31)11-34-26(21)35-12-19-7-8-24(40-19)22-10-20-23(13-33-22)36-14-37-25(20)32/h3-15,18,21,29H,16,19H2,1-2H3,(H,34,37)(H,35,39)(H,36,38);3-11,13,15-16H,12,14H2,1-2H3,(H,37,38)(H,39,42);4-15,17-18,20H,16H2,1-3H3,(H,32,34)(H,36,38);3-12,14-15,17H,13H2,1-2H3,(H,32,33)(H2,31,34,35);3-11,13-14,16H,12H2,1-2H3,(H,34,35)(H,38,39)(H2,32,36,37)/t21-,29-;;20-;17-;16-/m0.000/s1
InChIKeySNCJSZPDEDDCRE-OXHPMVCESA-N
MW2770.15 g/mol
LogP31.26
Rot. Bonds36

About 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide

2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide (PubChem CID 160881624) has the molecular formula C151H129F8N31O7S4 and a molecular weight of 2770.15 g/mol. Its IUPAC name is 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide.

Molecular Properties

Compound Name2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide
PubChem CID160881624
Molecular FormulaC151H129F8N31O7S4
Molecular Weight2770.15 g/mol
Exact Mass2767.94
IUPAC Name2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide
SMILESCc1ccc(CNC(=O)c2cc(C(F)(F)F)cnc2NCc2ccc(-c3ccc4ncc5ncn(C)c5c4c3)s2)cc1F.Cc1ccc([C@H](C)NC(=O)c2cc(C#N)cnc2N[C@@H](COc2ccc3c(c2)CC(=O)N3)c2ccccc2)cc1.Cc1ccc([C@H](C)NC(=O)c2cc(C(F)(F)F)cnc2NCc2ccc(-c3cc4c(N)ncnc4cn3)s2)cc1.Cc1ccc([C@H](C)NC(=O)c2cccnc2NCc2ccc(-c3ccc4ncc5ncn(C)c5c4c3)s2)cc1.Cc1ccc([C@H](C)n2cnc3ccnc(NCc4ccc(-c5ccc6ncnc(N)c6c5)s4)c3c2=O)cc1F
InChIInChI=1S/C32H29N5O3.C31H24F4N6OS.C31H28N6OS.C29H24FN7OS.C28H24F3N7OS/c1-20-8-10-23(11-9-20)21(2)35-32(39)27-14-22(17-33)18-34-31(27)37-29(24-6-4-3-5-7-24)19-40-26-12-13-28-25(15-26)16-30(38)36-28;1-17-3-4-18(9-24(17)32)12-39-30(42)23-11-20(31(33,34)35)13-37-29(23)38-14-21-6-8-27(43-21)19-5-7-25-22(10-19)28-26(15-36-25)40-16-41(28)2;1-19-6-8-21(9-7-19)20(2)36-31(38)24-5-4-14-32-30(24)34-16-23-11-13-28(39-23)22-10-12-26-25(15-22)29-27(17-33-26)35-18-37(29)3;1-16-3-4-18(12-22(16)30)17(2)37-15-36-24-9-10-32-28(26(24)29(37)38)33-13-20-6-8-25(39-20)19-5-7-23-21(11-19)27(31)35-14-34-23;1-15-3-5-17(6-4-15)16(2)38-27(39)21-9-18(28(29,30)31)11-34-26(21)35-12-19-7-8-24(40-19)22-10-20-23(13-33-22)36-14-37-25(20)32/h3-15,18,21,29H,16,19H2,1-2H3,(H,34,37)(H,35,39)(H,36,38);3-11,13,15-16H,12,14H2,1-2H3,(H,37,38)(H,39,42);4-15,17-18,20H,16H2,1-3H3,(H,32,34)(H,36,38);3-12,14-15,17H,13H2,1-2H3,(H,32,33)(H2,31,34,35);3-11,13-14,16H,12H2,1-2H3,(H,34,35)(H,38,39)(H2,32,36,37)/t21-,29-;;20-;17-;16-/m0.000/s1
InChIKeySNCJSZPDEDDCRE-OXHPMVCESA-N
XLogP31.26
TPSA515.92 Ų
H-Bond Donors12
H-Bond Acceptors37
Rotatable Bonds36
Heavy Atoms201
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002770.15
LogP ≤ 531.26
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1037

Analyze 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide with MolForge

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Related Compounds

2-[[5-(4-amino-7H-cyclopenta[d]pyrimidin-5-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide
CID 157109777
2-[[5-(4-amino-7H-cyclopenta[d]pyrimidin-5-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-4-methoxy-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;2-[[5-[4-(cyclopropylamino)quinazolin-6-yl]thiophen-2-yl]methylamino]-N-[(4-fluoro-3-methylphenyl)methyl]pyridine-3-carboxamide;N-[(4-fluoro-3-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide
CID 157579755
CID 157594248
CID 157594248
2-[[5-(4-amino-7H-cyclopenta[d]pyrimidin-5-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-4-methoxy-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[2-[4-(7H-cyclopenta[b]pyridin-5-yl)-2-pyridinyl]ethyl]-N-[(3-fluoro-4-methylphenyl)methyl]pyridine-3-carboxamide;2-[[5-[4-(cyclopropylamino)quinazolin-6-yl]thiophen-2-yl]methylamino]-N-[(3-fluoro-4-methylphenyl)methyl]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide
CID 157868405
N-[4-(4-acetylpiperazin-1-yl)phenyl]-3-aminothieno[2,3-b]pyridine-2-carboxamide;3-amino-N-(2,4-difluorophenyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-(3-fluorophenyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-(4-fluorophenyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-(3-methylsulfanylphenyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-(4-morpholin-4-ylphenyl)thieno[2,3-b]pyridine-2-carboxamide;3-amino-N-phenylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-(2,3,4-trifluorophenyl)thieno[2,3-b]pyridine-2-carboxamide;6-(2,3-dihydroindol-1-yl)-5-(trifluoromethylsulfonyl)pyrimidin-4-amine;(3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-1H-indol-2-one
CID 158602592
2-[[5-(4-amino-7H-cyclopenta[d]pyrimidin-5-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-4-methoxy-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-N-(4-methylphenyl)pyridine-3-carboxamide;2-[2-[4-(7H-cyclopenta[b]pyridin-5-yl)-2-pyridinyl]ethyl]-N-[(3-fluoro-4-methylphenyl)methyl]pyridine-3-carboxamide;2-[[5-[4-(cyclopropylamino)quinazolin-6-yl]thiophen-2-yl]methylamino]-N-[(3-fluoro-4-methylphenyl)methyl]pyridine-3-carboxamide;N-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]-2-[2-[[(1Z)-2-oxo-1-(3H-pyrrol-4-ylmethylidene)-3H-inden-5-yl]oxy]ethylamino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]-5-(trifluoromethyl)pyridine-3-carboxamide
CID 159145003
methyl 2-[[4-[6-[(7-cyano-3,4-dihydro-2H-chromen-4-yl)oxy]-2-pyridinyl]-2-fluorophenyl]methyl]-3-(2-methoxyethyl)benzimidazole-5-carboxylate;methyl 2-[[4-[6-[(5-cyanothiophen-3-yl)methoxy]-2-pyridinyl]-2-fluorophenyl]methyl]-3-(2-methoxyethyl)benzimidazole-5-carboxylate;methyl 2-[[2-fluoro-4-[6-[[4-(3-fluorooxetan-3-yl)phenyl]methoxy]-2-pyridinyl]phenyl]methyl]-3-(2-methoxyethyl)benzimidazole-5-carboxylate;methyl 2-[[2-fluoro-4-[6-(1H-indol-7-ylmethoxy)-2-pyridinyl]phenyl]methyl]-3-(2-methoxyethyl)benzimidazole-5-carboxylate;methyl 2-[[2-fluoro-4-[6-[[2-methoxy-4-(trifluoromethyl)phenyl]methoxy]-2-pyridinyl]phenyl]methyl]-3-(2-methoxyethyl)benzimidazole-5-carboxylate
CID 159209425
N-[6-[3-(1,1-difluoroethoxy)phenyl]pyrido[3,2-d]pyrimidin-4-yl]-1,3-thiazole-4-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-3-pyridinyl]quinoline-8-carboxamide;2-[3-(1-fluoroethyl)phenyl]-N-[4-(morpholin-4-ylmethyl)phenyl]quinoline-8-carboxamide;7-[3-(1-fluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-2-pyridinyl]naphthalene-1-carboxamide;2-[2-(1-fluoroethyl)-4-pyridinyl]-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide
CID 159499663
3-[[(1R)-1-[4-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)phenyl]ethyl]amino]-6-cyano-N-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrazine-2-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-4-methoxy-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-N-(4-methylphenyl)pyridine-3-carboxamide;2-[2-[4-(7H-cyclopenta[b]pyridin-5-yl)-2-pyridinyl]ethyl]-N-[(3-fluoro-4-methylphenyl)methyl]pyridine-3-carboxamide;N-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]-2-[2-[[(1Z)-2-oxo-1-(3H-pyrrol-4-ylmethylidene)-3H-inden-5-yl]oxy]ethylamino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]-5-(trifluoromethyl)pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[4-(1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl]methylamino]pyridine-3-carboxamide
CID 159818401
3-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-6-cyano-N-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrazine-2-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-5-cyano-N-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-5-ethoxy-N-[(3-fluoro-4-methylphenyl)methyl]pyridine-3-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-N-[(3-fluoro-4-methylphenyl)methyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[4-(1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl]methylamino]pyridine-3-carboxamide
CID 160358794
N-tert-butyl-6-[3-cyano-6-ethyl-5-fluoro-1-(3-fluoro-2-pyridinyl)indol-2-yl]pyridine-3-sulfonamide;N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrazin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-5-methyl-1-pyrimidin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-pyrazin-2-yl-5-(trifluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;5-fluoro-1-(3-fluoro-2-pyridinyl)-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;6-[5-fluoro-6-methyl-1-(1,3-thiazol-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
CID 160651151
5-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(4-fluoro-3-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-5-cyano-N-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-N-[(3-fluoro-4-methylphenyl)methyl]-5-(trifluoromethyl)pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydrobenzimidazol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide
CID 160874568

Frequently Asked Questions

What is the IUPAC name of 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide?
The IUPAC name of 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide (CID 160881624) is 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide.
What is the SMILES notation for 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide?
The canonical SMILES for 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide is Cc1ccc(CNC(=O)c2cc(C(F)(F)F)cnc2NCc2ccc(-c3ccc4ncc5ncn(C)c5c4c3)s2)cc1F.Cc1ccc([C@H](C)NC(=O)c2cc(C#N)cnc2N[C@@H](COc2ccc3c(c2)CC(=O)N3)c2ccccc2)cc1.Cc1ccc([C@H](C)NC(=O)c2cc(C(F)(F)F)cnc2NCc2ccc(-c3cc4c(N)ncnc4cn3)s2)cc1.Cc1ccc([C@H](C)NC(=O)c2cccnc2NCc2ccc(-c3ccc4ncc5ncn(C)c5c4c3)s2)cc1.Cc1ccc([C@H](C)n2cnc3ccnc(NCc4ccc(-c5ccc6ncnc(N)c6c5)s4)c3c2=O)cc1F.
What is the InChIKey of 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide?
The InChIKey is SNCJSZPDEDDCRE-OXHPMVCESA-N. The full InChI is InChI=1S/C32H29N5O3.C31H24F4N6OS.C31H28N6OS.C29H24FN7OS.C28H24F3N7OS/c1-20-8-10-23(11-9-20)21(2)35-32(39)27-14-22(17-33)18-34-31(27)37-29(24-6-4-3-5-7-24)19-40-26-12-13-28-25(15-26)16-30(38)36-28;1-17-3-4-18(9-24(17)32)12-39-30(42)23-11-20(31(33,34)35)13-37-29(23)38-14-21-6-8-27(43-21)19-5-7-25-22(10-19)28-26(15-36-25)40-16-41(28)2;1-19-6-8-21(9-7-19)20(2)36-31(38)24-5-4-14-32-30(24)34-16-23-11-13-28(39-23)22-10-12-26-25(15-22)29-27(17-33-26)35-18-37(29)3;1-16-3-4-18(12-22(16)30)17(2)37-15-36-24-9-10-32-28(26(24)29(37)38)33-13-20-6-8-25(39-20)19-5-7-23-21(11-19)27(31)35-14-34-23;1-15-3-5-17(6-4-15)16(2)38-27(39)21-9-18(28(29,30)31)11-34-26(21)35-12-19-7-8-24(40-19)22-10-20-23(13-33-22)36-14-37-25(20)32/h3-15,18,21,29H,16,19H2,1-2H3,(H,34,37)(H,35,39)(H,36,38);3-11,13,15-16H,12,14H2,1-2H3,(H,37,38)(H,39,42);4-15,17-18,20H,16H2,1-3H3,(H,32,34)(H,36,38);3-12,14-15,17H,13H2,1-2H3,(H,32,33)(H2,31,34,35);3-11,13-14,16H,12H2,1-2H3,(H,34,35)(H,38,39)(H2,32,36,37)/t21-,29-;;20-;17-;16-/m0.000/s1.
What are the key properties of 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide?
2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide has a molecular weight of 2770.15 g/mol, XLogP of 31.26, 36 rotatable bonds, 12 hydrogen bond donors, and 37 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[[5-(4-aminopyrido[3,4-d]pyrimidin-6-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]-5-(trifluoromethyl)pyridine-3-carboxamide;5-[[5-(4-aminoquinazolin-6-yl)thiophen-2-yl]methylamino]-3-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrido[4,3-d]pyrimidin-4-one;5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]-2-[[(1R)-2-[(2-oxo-1,3-dihydroindol-5-yl)oxy]-1-phenylethyl]amino]pyridine-3-carboxamide;N-[(3-fluoro-4-methylphenyl)methyl]-2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-5-(trifluoromethyl)pyridine-3-carboxamide;2-[[5-(1-methylimidazo[4,5-c]quinolin-8-yl)thiophen-2-yl]methylamino]-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide is sourced from PubChem (CID 160881624), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).