N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide

C240H238Cl2F23N57O38S13 — CID 160884435

IUPACN-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide
SMILESCCCS(=O)(=O)Nc1ccc(Cl)c(C(=O)Cc2cnc3n[nH]c(C4CC4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3[nH]nc(-n4ccnc4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3[nH]nc(N(CC)CC)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3[nH]nc(SC)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3n[nH]c(C4=CCN(C)CC4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3n[nH]c(Nc4ccccc4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(NC)c3c2)c1F.CCCS(=O)(=O)Nc1cccc(C(=O)Cc2cnc3n[nH]c(C4CC4)c3c2)c1F.COc1n[nH]c2ncc(CC(=O)c3c(Cl)ccc(NS(=O)(=O)CCCF)c3F)cc12.COc1n[nH]c2ncc(CC(=O)c3cccc(NS(=O)(=O)CCCF)c3F)cc12.O=C(Cc1cnc2n[nH]c(-c3ccccn3)c2c1)c1c(F)ccc(NS(=O)(=O)CCCF)c1F.O=C(Nc1cnc2n[nH]c(C3CC3)c2c1)c1c(F)ccc(NS(=O)(=O)CC2CC2)c1F
InChIInChI=1S/C23H25F2N5O3S.C23H21F2N5O3S.C22H18F3N5O3S.C21H25F2N5O3S.C20H20ClFN4O3S.C20H18F2N6O3S.C20H19F2N5O3S.C20H21FN4O3S.C18H17ClF2N4O4S.C18H18F2N4O4S.C18H18F2N4O3S2.C17H18F2N6O3S/c1-3-10-34(32,33)29-18-5-4-17(24)20(21(18)25)19(31)12-14-11-16-22(27-28-23(16)26-13-14)15-6-8-30(2)9-7-15;1-2-10-34(32,33)30-18-9-8-17(24)20(21(18)25)19(31)12-14-11-16-22(26-13-14)28-29-23(16)27-15-6-4-3-5-7-15;23-7-3-9-34(32,33)30-16-6-5-15(24)19(20(16)25)18(31)11-13-10-14-21(17-4-1-2-8-26-17)28-29-22(14)27-12-13;1-4-9-32(30,31)27-16-8-7-15(22)18(19(16)23)17(29)11-13-10-14-20(24-12-13)25-26-21(14)28(5-2)6-3;1-2-7-30(28,29)26-15-6-5-14(21)17(18(15)22)16(27)9-11-8-13-19(12-3-4-12)24-25-20(13)23-10-11;1-2-7-32(30,31)27-15-4-3-14(21)17(18(15)22)16(29)9-12-8-13-19(24-10-12)25-26-20(13)28-6-5-23-11-28;21-14-5-6-15(27-31(29,30)9-10-1-2-10)17(22)16(14)20(28)24-12-7-13-18(11-3-4-11)25-26-19(13)23-8-12;1-2-8-29(27,28)25-16-5-3-4-14(18(16)21)17(26)10-12-9-15-19(13-6-7-13)23-24-20(15)22-11-12;1-29-18-11-7-10(9-22-17(11)23-24-18)8-14(26)15-12(19)3-4-13(16(15)21)25-30(27,28)6-2-5-20;1-28-18-13-8-11(10-21-17(13)22-23-18)9-15(25)12-4-2-5-14(16(12)20)24-29(26,27)7-3-6-19;1-3-6-29(26,27)24-13-5-4-12(19)15(16(13)20)14(25)8-10-7-11-17(21-9-10)22-23-18(11)28-2;1-3-6-29(27,28)25-12-5-4-11(18)13(14(12)19)17(26)22-9-7-10-15(20-2)23-24-16(10)21-8-9/h4-6,11,13,29H,3,7-10,12H2,1-2H3,(H,26,27,28);3-9,11,13,30H,2,10,12H2,1H3,(H2,26,27,28,29);1-2,4-6,8,10,12,30H,3,7,9,11H2,(H,27,28,29);7-8,10,12,27H,4-6,9,11H2,1-3H3,(H,24,25,26);5-6,8,10,12,26H,2-4,7,9H2,1H3,(H,23,24,25);3-6,8,10-11,27H,2,7,9H2,1H3,(H,24,25,26);5-8,10-11,27H,1-4,9H2,(H,24,28)(H,23,25,26);3-5,9,11,13,25H,2,6-8,10H2,1H3,(H,22,23,24);3-4,7,9,25H,2,5-6,8H2,1H3,(H,22,23,24);2,4-5,8,10,24H,3,6-7,9H2,1H3,(H,21,22,23);4-5,7,9,24H,3,6,8H2,1-2H3,(H,21,22,23);4-5,7-8,25H,3,6H2,1-2H3,(H,22,26)(H2,20,21,23,24)
InChIKeySNLIIHOUVCNHIA-UHFFFAOYSA-N
MW5453.64 g/mol
LogP41.98
Rot. Bonds100

About N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide

N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide (PubChem CID 160884435) has the molecular formula C240H238Cl2F23N57O38S13 and a molecular weight of 5453.64 g/mol. Its IUPAC name is N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide.

Molecular Properties

Compound NameN-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide
PubChem CID160884435
Molecular FormulaC240H238Cl2F23N57O38S13
Molecular Weight5453.64 g/mol
Exact Mass5448.38
IUPAC NameN-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide
SMILESCCCS(=O)(=O)Nc1ccc(Cl)c(C(=O)Cc2cnc3n[nH]c(C4CC4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3[nH]nc(-n4ccnc4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3[nH]nc(N(CC)CC)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3[nH]nc(SC)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3n[nH]c(C4=CCN(C)CC4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3n[nH]c(Nc4ccccc4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(NC)c3c2)c1F.CCCS(=O)(=O)Nc1cccc(C(=O)Cc2cnc3n[nH]c(C4CC4)c3c2)c1F.COc1n[nH]c2ncc(CC(=O)c3c(Cl)ccc(NS(=O)(=O)CCCF)c3F)cc12.COc1n[nH]c2ncc(CC(=O)c3cccc(NS(=O)(=O)CCCF)c3F)cc12.O=C(Cc1cnc2n[nH]c(-c3ccccn3)c2c1)c1c(F)ccc(NS(=O)(=O)CCCF)c1F.O=C(Nc1cnc2n[nH]c(C3CC3)c2c1)c1c(F)ccc(NS(=O)(=O)CC2CC2)c1F
InChIInChI=1S/C23H25F2N5O3S.C23H21F2N5O3S.C22H18F3N5O3S.C21H25F2N5O3S.C20H20ClFN4O3S.C20H18F2N6O3S.C20H19F2N5O3S.C20H21FN4O3S.C18H17ClF2N4O4S.C18H18F2N4O4S.C18H18F2N4O3S2.C17H18F2N6O3S/c1-3-10-34(32,33)29-18-5-4-17(24)20(21(18)25)19(31)12-14-11-16-22(27-28-23(16)26-13-14)15-6-8-30(2)9-7-15;1-2-10-34(32,33)30-18-9-8-17(24)20(21(18)25)19(31)12-14-11-16-22(26-13-14)28-29-23(16)27-15-6-4-3-5-7-15;23-7-3-9-34(32,33)30-16-6-5-15(24)19(20(16)25)18(31)11-13-10-14-21(17-4-1-2-8-26-17)28-29-22(14)27-12-13;1-4-9-32(30,31)27-16-8-7-15(22)18(19(16)23)17(29)11-13-10-14-20(24-12-13)25-26-21(14)28(5-2)6-3;1-2-7-30(28,29)26-15-6-5-14(21)17(18(15)22)16(27)9-11-8-13-19(12-3-4-12)24-25-20(13)23-10-11;1-2-7-32(30,31)27-15-4-3-14(21)17(18(15)22)16(29)9-12-8-13-19(24-10-12)25-26-20(13)28-6-5-23-11-28;21-14-5-6-15(27-31(29,30)9-10-1-2-10)17(22)16(14)20(28)24-12-7-13-18(11-3-4-11)25-26-19(13)23-8-12;1-2-8-29(27,28)25-16-5-3-4-14(18(16)21)17(26)10-12-9-15-19(13-6-7-13)23-24-20(15)22-11-12;1-29-18-11-7-10(9-22-17(11)23-24-18)8-14(26)15-12(19)3-4-13(16(15)21)25-30(27,28)6-2-5-20;1-28-18-13-8-11(10-21-17(13)22-23-18)9-15(25)12-4-2-5-14(16(12)20)24-29(26,27)7-3-6-19;1-3-6-29(26,27)24-13-5-4-12(19)15(16(13)20)14(25)8-10-7-11-17(21-9-10)22-23-18(11)28-2;1-3-6-29(27,28)25-12-5-4-11(18)13(14(12)19)17(26)22-9-7-10-15(20-2)23-24-16(10)21-8-9/h4-6,11,13,29H,3,7-10,12H2,1-2H3,(H,26,27,28);3-9,11,13,30H,2,10,12H2,1H3,(H2,26,27,28,29);1-2,4-6,8,10,12,30H,3,7,9,11H2,(H,27,28,29);7-8,10,12,27H,4-6,9,11H2,1-3H3,(H,24,25,26);5-6,8,10,12,26H,2-4,7,9H2,1H3,(H,23,24,25);3-6,8,10-11,27H,2,7,9H2,1H3,(H,24,25,26);5-8,10-11,27H,1-4,9H2,(H,24,28)(H,23,25,26);3-5,9,11,13,25H,2,6-8,10H2,1H3,(H,22,23,24);3-4,7,9,25H,2,5-6,8H2,1H3,(H,22,23,24);2,4-5,8,10,24H,3,6-7,9H2,1H3,(H,21,22,23);4-5,7,9,24H,3,6,8H2,1-2H3,(H,21,22,23);4-5,7-8,25H,3,6H2,1-2H3,(H,22,26)(H2,20,21,23,24)
InChIKeySNLIIHOUVCNHIA-UHFFFAOYSA-N
XLogP41.98
TPSA1361.49 Ų
H-Bond Donors28
H-Bond Acceptors70
Rotatable Bonds100
Heavy Atoms373
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005453.64
LogP ≤ 541.98
H-Bond Donors ≤ 528
H-Bond Acceptors ≤ 1070

Analyze N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide?
The IUPAC name of N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide (CID 160884435) is N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide.
What is the SMILES notation for N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide?
The canonical SMILES for N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide is CCCS(=O)(=O)Nc1ccc(Cl)c(C(=O)Cc2cnc3n[nH]c(C4CC4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3[nH]nc(-n4ccnc4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3[nH]nc(N(CC)CC)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3[nH]nc(SC)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3n[nH]c(C4=CCN(C)CC4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Cc2cnc3n[nH]c(Nc4ccccc4)c3c2)c1F.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(NC)c3c2)c1F.CCCS(=O)(=O)Nc1cccc(C(=O)Cc2cnc3n[nH]c(C4CC4)c3c2)c1F.COc1n[nH]c2ncc(CC(=O)c3c(Cl)ccc(NS(=O)(=O)CCCF)c3F)cc12.COc1n[nH]c2ncc(CC(=O)c3cccc(NS(=O)(=O)CCCF)c3F)cc12.O=C(Cc1cnc2n[nH]c(-c3ccccn3)c2c1)c1c(F)ccc(NS(=O)(=O)CCCF)c1F.O=C(Nc1cnc2n[nH]c(C3CC3)c2c1)c1c(F)ccc(NS(=O)(=O)CC2CC2)c1F.
What is the InChIKey of N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide?
The InChIKey is SNLIIHOUVCNHIA-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H25F2N5O3S.C23H21F2N5O3S.C22H18F3N5O3S.C21H25F2N5O3S.C20H20ClFN4O3S.C20H18F2N6O3S.C20H19F2N5O3S.C20H21FN4O3S.C18H17ClF2N4O4S.C18H18F2N4O4S.C18H18F2N4O3S2.C17H18F2N6O3S/c1-3-10-34(32,33)29-18-5-4-17(24)20(21(18)25)19(31)12-14-11-16-22(27-28-23(16)26-13-14)15-6-8-30(2)9-7-15;1-2-10-34(32,33)30-18-9-8-17(24)20(21(18)25)19(31)12-14-11-16-22(26-13-14)28-29-23(16)27-15-6-4-3-5-7-15;23-7-3-9-34(32,33)30-16-6-5-15(24)19(20(16)25)18(31)11-13-10-14-21(17-4-1-2-8-26-17)28-29-22(14)27-12-13;1-4-9-32(30,31)27-16-8-7-15(22)18(19(16)23)17(29)11-13-10-14-20(24-12-13)25-26-21(14)28(5-2)6-3;1-2-7-30(28,29)26-15-6-5-14(21)17(18(15)22)16(27)9-11-8-13-19(12-3-4-12)24-25-20(13)23-10-11;1-2-7-32(30,31)27-15-4-3-14(21)17(18(15)22)16(29)9-12-8-13-19(24-10-12)25-26-20(13)28-6-5-23-11-28;21-14-5-6-15(27-31(29,30)9-10-1-2-10)17(22)16(14)20(28)24-12-7-13-18(11-3-4-11)25-26-19(13)23-8-12;1-2-8-29(27,28)25-16-5-3-4-14(18(16)21)17(26)10-12-9-15-19(13-6-7-13)23-24-20(15)22-11-12;1-29-18-11-7-10(9-22-17(11)23-24-18)8-14(26)15-12(19)3-4-13(16(15)21)25-30(27,28)6-2-5-20;1-28-18-13-8-11(10-21-17(13)22-23-18)9-15(25)12-4-2-5-14(16(12)20)24-29(26,27)7-3-6-19;1-3-6-29(26,27)24-13-5-4-12(19)15(16(13)20)14(25)8-10-7-11-17(21-9-10)22-23-18(11)28-2;1-3-6-29(27,28)25-12-5-4-11(18)13(14(12)19)17(26)22-9-7-10-15(20-2)23-24-16(10)21-8-9/h4-6,11,13,29H,3,7-10,12H2,1-2H3,(H,26,27,28);3-9,11,13,30H,2,10,12H2,1H3,(H2,26,27,28,29);1-2,4-6,8,10,12,30H,3,7,9,11H2,(H,27,28,29);7-8,10,12,27H,4-6,9,11H2,1-3H3,(H,24,25,26);5-6,8,10,12,26H,2-4,7,9H2,1H3,(H,23,24,25);3-6,8,10-11,27H,2,7,9H2,1H3,(H,24,25,26);5-8,10-11,27H,1-4,9H2,(H,24,28)(H,23,25,26);3-5,9,11,13,25H,2,6-8,10H2,1H3,(H,22,23,24);3-4,7,9,25H,2,5-6,8H2,1H3,(H,22,23,24);2,4-5,8,10,24H,3,6-7,9H2,1H3,(H,21,22,23);4-5,7,9,24H,3,6,8H2,1-2H3,(H,21,22,23);4-5,7-8,25H,3,6H2,1-2H3,(H,22,26)(H2,20,21,23,24).
What are the key properties of N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide?
N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide has a molecular weight of 5453.64 g/mol, XLogP of 41.98, 100 rotatable bonds, 28 hydrogen bond donors, and 70 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3-[2-(3-anilino-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[4-chloro-3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[4-chloro-2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-(cyclopropylmethylsulfonylamino)-N-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)-2,6-difluorobenzamide;N-[3-[2-(3-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]-2-fluorophenyl]propane-1-sulfonamide;N-[3-[2-[3-(diethylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]acetyl]-2,4-difluorophenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-imidazol-1-yl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;2,6-difluoro-N-[3-(methylamino)-1H-pyrazolo[5,4-b]pyridin-5-yl]-3-(propylsulfonylamino)benzamide;N-[2,4-difluoro-3-[2-[3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridin-5-yl]acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-methylsulfanyl-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide;N-[2,4-difluoro-3-[2-(3-pyridin-2-yl-2H-pyrazolo[3,4-b]pyridin-5-yl)acetyl]phenyl]-3-fluoropropane-1-sulfonamide;3-fluoro-N-[2-fluoro-3-[2-(3-methoxy-1H-pyrazolo[5,4-b]pyridin-5-yl)acetyl]phenyl]propane-1-sulfonamide is sourced from PubChem (CID 160884435), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).