N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide

C80H94F3N17O13S3 — CID 160899177

IUPACN-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide
SMILESCC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCCC(C)(C)C3)n2)c1.CC(C)Oc1ccc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCC(F)(F)CC3)n2)cn1.CC(C)Oc1ccc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCC(OCC4CC4)CC3)n2)cn1
InChIInChI=1S/C28H34FN5O4S.C28H34N6O5S.C24H26F2N6O4S/c1-18(2)16-38-21-14-19(13-20(29)15-21)23-10-9-22(26(31-23)34-12-6-11-28(3,4)17-34)27(35)33-39(36,37)25-8-5-7-24(30)32-25;1-18(2)39-25-11-8-20(16-30-25)23-10-9-22(28(35)33-40(36,37)26-5-3-4-24(29)32-26)27(31-23)34-14-12-21(13-15-34)38-17-19-6-7-19;1-15(2)36-20-9-6-16(14-28-20)18-8-7-17(22(29-18)32-12-10-24(25,26)11-13-32)23(33)31-37(34,35)21-5-3-4-19(27)30-21/h5,7-10,13-15,18H,6,11-12,16-17H2,1-4H3,(H2,30,32)(H,33,35);3-5,8-11,16,18-19,21H,6-7,12-15,17H2,1-2H3,(H2,29,32)(H,33,35);3-9,14-15H,10-13H2,1-2H3,(H2,27,30)(H,31,33)
InChIKeySPGSCJSKNUMIRK-UHFFFAOYSA-N
MW1654.93 g/mol
LogP11.33
Rot. Bonds25

About N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide

N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide (PubChem CID 160899177) has the molecular formula C80H94F3N17O13S3 and a molecular weight of 1654.93 g/mol. Its IUPAC name is N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide.

Molecular Properties

Compound NameN-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide
PubChem CID160899177
Molecular FormulaC80H94F3N17O13S3
Molecular Weight1654.93 g/mol
Exact Mass1653.63
IUPAC NameN-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide
SMILESCC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCCC(C)(C)C3)n2)c1.CC(C)Oc1ccc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCC(F)(F)CC3)n2)cn1.CC(C)Oc1ccc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCC(OCC4CC4)CC3)n2)cn1
InChIInChI=1S/C28H34FN5O4S.C28H34N6O5S.C24H26F2N6O4S/c1-18(2)16-38-21-14-19(13-20(29)15-21)23-10-9-22(26(31-23)34-12-6-11-28(3,4)17-34)27(35)33-39(36,37)25-8-5-7-24(30)32-25;1-18(2)39-25-11-8-20(16-30-25)23-10-9-22(28(35)33-40(36,37)26-5-3-4-24(29)32-26)27(31-23)34-14-12-21(13-15-34)38-17-19-6-7-19;1-15(2)36-20-9-6-16(14-28-20)18-8-7-17(22(29-18)32-12-10-24(25,26)11-13-32)23(33)31-37(34,35)21-5-3-4-19(27)30-21/h5,7-10,13-15,18H,6,11-12,16-17H2,1-4H3,(H2,30,32)(H,33,35);3-5,8-11,16,18-19,21H,6-7,12-15,17H2,1-2H3,(H2,29,32)(H,33,35);3-9,14-15H,10-13H2,1-2H3,(H2,27,30)(H,31,33)
InChIKeySPGSCJSKNUMIRK-UHFFFAOYSA-N
XLogP11.33
TPSA417.54 Ų
H-Bond Donors6
H-Bond Acceptors27
Rotatable Bonds25
Heavy Atoms116
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001654.93
LogP ≤ 511.33
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1027

Analyze N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide with MolForge

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Related Compounds

N-(6-aminopyridin-2-yl)sulfonyl-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide
CID 121250426
N-[(6-amino-2-pyridinyl)sulfonyl]-2-(2-azabicyclo[4.1.0]heptan-2-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide
CID 121250430
N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-(2-pyridin-2-ylpyrrolidin-1-yl)pyridine-3-carboxamide
CID 121250438
N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-(2,2,4-trimethylpiperidin-1-yl)pyridine-3-carboxamide
CID 121250468
N-[(6-amino-2-pyridinyl)sulfonyl]-2-(2-azaspiro[3.3]heptan-2-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide
CID 121250480
N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[3-(methoxymethyl)piperidin-1-yl]pyridine-3-carboxamide
CID 121250484
N-(6-aminopyridin-2-yl)sulfonyl-6-(6-propan-2-yloxypyridin-3-yl)-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]pyridine-3-carboxamide
CID 121250496
N-(6-aminopyridin-2-yl)sulfonyl-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[(2R)-2-(trifluoromethyl)pyrrolidin-1-yl]pyridine-3-carboxamide
CID 121250501
N-[(6-amino-2-pyridinyl)sulfonyl]-2-(2,5-dihydropyrrol-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide
CID 121250546
N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-(2-phenylpyrrolidin-1-yl)pyridine-3-carboxamide
CID 121250566
N-(6-aminopyridin-2-yl)sulfonyl-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxypyridin-3-yl)pyridine-3-carboxamide
CID 121250573
N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3-ethyl-3-methylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide
CID 121250613

Frequently Asked Questions

What is the IUPAC name of N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide?
The IUPAC name of N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide (CID 160899177) is N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide.
What is the SMILES notation for N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide?
The canonical SMILES for N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide is CC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCCC(C)(C)C3)n2)c1.CC(C)Oc1ccc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCC(F)(F)CC3)n2)cn1.CC(C)Oc1ccc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CCC(OCC4CC4)CC3)n2)cn1.
What is the InChIKey of N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide?
The InChIKey is SPGSCJSKNUMIRK-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H34FN5O4S.C28H34N6O5S.C24H26F2N6O4S/c1-18(2)16-38-21-14-19(13-20(29)15-21)23-10-9-22(26(31-23)34-12-6-11-28(3,4)17-34)27(35)33-39(36,37)25-8-5-7-24(30)32-25;1-18(2)39-25-11-8-20(16-30-25)23-10-9-22(28(35)33-40(36,37)26-5-3-4-24(29)32-26)27(31-23)34-14-12-21(13-15-34)38-17-19-6-7-19;1-15(2)36-20-9-6-16(14-28-20)18-8-7-17(22(29-18)32-12-10-24(25,26)11-13-32)23(33)31-37(34,35)21-5-3-4-19(27)30-21/h5,7-10,13-15,18H,6,11-12,16-17H2,1-4H3,(H2,30,32)(H,33,35);3-5,8-11,16,18-19,21H,6-7,12-15,17H2,1-2H3,(H2,29,32)(H,33,35);3-9,14-15H,10-13H2,1-2H3,(H2,27,30)(H,31,33).
What are the key properties of N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide?
N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide has a molecular weight of 1654.93 g/mol, XLogP of 11.33, 25 rotatable bonds, 6 hydrogen bond donors, and 27 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(6-amino-2-pyridinyl)sulfonyl]-2-[4-(cyclopropylmethoxy)piperidin-1-yl]-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoropiperidin-1-yl)-6-(6-propan-2-yloxy-3-pyridinyl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-2-(3,3-dimethylpiperidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide is sourced from PubChem (CID 160899177), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).