2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide

C113H82ClF7N24O21S12 — CID 160901906

About 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide

2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide (PubChem CID 160901906) has the molecular formula C113H82ClF7N24O21S12 and a molecular weight of 2665.29 g/mol. Its IUPAC name is 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide.

Molecular Properties

• Compound Name: 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide
• PubChem CID: 160901906
• Molecular Formula: C113H82ClF7N24O21S12
• Molecular Weight: 2665.29 g/mol
• Exact Mass: 2662.23
• IUPAC Name: 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide
• SMILES: CC(Oc1ccccc1)C(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12.O=C(COc1ccc(F)c(Cl)c1)Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12.O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12.O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12)C(F)(F)F.O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12)c1cc(F)ccc1F.O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12)c1ccccc1F
• InChI: InChI=1S/C21H18N4O4S2.C20H14ClFN4O4S2.C20H16N4O4S2.C19H12F2N4O3S2.C19H13FN4O3S2.C14H9F3N4O3S2/c1-14(29-15-6-3-2-4-7-15)20(26)24-17-9-10-18(16-8-5-11-22-19(16)17)31(27,28)25-21-23-12-13-30-21;21-14-10-12(3-4-15(14)22)30-11-18(27)25-16-5-6-17(13-2-1-7-23-19(13)16)32(28,29)26-20-24-8-9-31-20;25-18(13-28-14-5-2-1-3-6-14)23-16-8-9-17(15-7-4-10-21-19(15)16)30(26,27)24-20-22-11-12-29-20;20-11-3-4-14(21)13(10-11)18(26)24-15-5-6-16(12-2-1-7-22-17(12)15)30(27,28)25-19-23-8-9-29-19;20-14-6-2-1-4-12(14)18(25)23-15-7-8-16(13-5-3-9-21-17(13)15)29(26,27)24-19-22-10-11-28-19;15-14(16,17)12(22)20-9-3-4-10(8-2-1-5-18-11(8)9)26(23,24)21-13-19-6-7-25-13/h2-14H,1H3,(H,23,25)(H,24,26);1-10H,11H2,(H,24,26)(H,25,27);1-12H,13H2,(H,22,24)(H,23,25);1-10H,(H,23,25)(H,24,26);1-11H,(H,22,24)(H,23,25);1-7H,(H,19,21)(H,20,22)
• InChIKey: SPPRRPCKAXJDNU-UHFFFAOYSA-N
• XLogP: 22.61
• TPSA: 633.99 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 39
• Rotatable Bonds: 35
• Heavy Atoms: 178
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2665.29
LogP ≤ 5	22.61
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	39

Frequently Asked Questions

What is the IUPAC name of 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide?

The IUPAC name of 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide (CID 160901906) is 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide.

What is the SMILES notation for 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide?

The canonical SMILES for 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide is CC(Oc1ccccc1)C(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12.O=C(COc1ccc(F)c(Cl)c1)Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12.O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12.O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12)C(F)(F)F.O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12)c1cc(F)ccc1F.O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)c2cccnc12)c1ccccc1F.

What is the InChIKey of 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide?

The InChIKey is SPPRRPCKAXJDNU-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H18N4O4S2.C20H14ClFN4O4S2.C20H16N4O4S2.C19H12F2N4O3S2.C19H13FN4O3S2.C14H9F3N4O3S2/c1-14(29-15-6-3-2-4-7-15)20(26)24-17-9-10-18(16-8-5-11-22-19(16)17)31(27,28)25-21-23-12-13-30-21;21-14-10-12(3-4-15(14)22)30-11-18(27)25-16-5-6-17(13-2-1-7-23-19(13)16)32(28,29)26-20-24-8-9-31-20;25-18(13-28-14-5-2-1-3-6-14)23-16-8-9-17(15-7-4-10-21-19(15)16)30(26,27)24-20-22-11-12-29-20;20-11-3-4-14(21)13(10-11)18(26)24-15-5-6-16(12-2-1-7-22-17(12)15)30(27,28)25-19-23-8-9-29-19;20-14-6-2-1-4-12(14)18(25)23-15-7-8-16(13-5-3-9-21-17(13)15)29(26,27)24-19-22-10-11-28-19;15-14(16,17)12(22)20-9-3-4-10(8-2-1-5-18-11(8)9)26(23,24)21-13-19-6-7-25-13/h2-14H,1H3,(H,23,25)(H,24,26);1-10H,11H2,(H,24,26)(H,25,27);1-12H,13H2,(H,22,24)(H,23,25);1-10H,(H,23,25)(H,24,26);1-11H,(H,22,24)(H,23,25);1-7H,(H,19,21)(H,20,22).

What are the key properties of 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide?

2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide has a molecular weight of 2665.29 g/mol, XLogP of 22.61, 35 rotatable bonds, 12 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(3-chloro-4-fluorophenoxy)-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2,5-difluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-fluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]benzamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide;2-phenoxy-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]propanamide;2,2,2-trifluoro-N-[5-(1,3-thiazol-2-ylsulfamoyl)quinolin-8-yl]acetamide is sourced from PubChem (CID 160901906), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).