5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione

C119H112Cl4F3N25O15 — CID 160906196

About 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione

5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione (PubChem CID 160906196) has the molecular formula C119H112Cl4F3N25O15 and a molecular weight of 2331.17 g/mol. Its IUPAC name is 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione.

Molecular Properties

• Compound Name: 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione
• PubChem CID: 160906196
• Molecular Formula: C119H112Cl4F3N25O15
• Molecular Weight: 2331.17 g/mol
• Exact Mass: 2327.75
• IUPAC Name: 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione
• SMILES: COc1cc(OCCF)ncc1-c1nc2c(n1C(C)C)C1(C(=O)Nc3cc(C)ccc31)N(c1cc(Cl)cnc1C)C2=O.COc1nc(C(C)C)ncc1-c1nc2c(n1C(C)C)C1(C(=O)Nc3cc(C)ccc31)N(c1cc(Cl)ccc1C)C2=O.COc1nc(OCCF)ncc1-c1nc2c(n1C(C)C)C1(C(=O)Nc3cc(C)ccc31)N(c1cc(Cl)cnc1C)C2=O.COc1nc(OCCF)ncc1-c1nc2c(n1C(C)C)C1(C(=O)Nc3cc(C)ccc31)N(c1cccc(Cl)c1)C2=O
• InChI: InChI=1S/C31H31ClN6O3.C30H28ClFN6O4.C29H27ClFN7O4.C29H26ClFN6O4/c1-15(2)26-33-14-20(28(36-26)41-7)27-35-24-25(37(27)16(3)4)31(21-11-8-17(5)12-22(21)34-30(31)40)38(29(24)39)23-13-19(32)10-9-18(23)6;1-15(2)37-26-25(36-27(37)19-14-34-24(42-9-8-32)12-23(19)41-5)28(39)38(22-11-18(31)13-33-17(22)4)30(26)20-7-6-16(3)10-21(20)35-29(30)40;1-14(2)37-23-22(35-24(37)18-13-33-28(42-9-8-31)36-25(18)41-5)26(39)38(21-11-17(30)12-32-16(21)4)29(23)19-7-6-15(3)10-20(19)34-27(29)40;1-15(2)36-23-22(34-24(36)19-14-32-28(41-11-10-31)35-25(19)40-4)26(38)37(18-7-5-6-17(30)13-18)29(23)20-9-8-16(3)12-21(20)33-27(29)39/h8-16H,1-7H3,(H,34,40);6-7,10-15H,8-9H2,1-5H3,(H,35,40);6-7,10-14H,8-9H2,1-5H3,(H,34,40);5-9,12-15H,10-11H2,1-4H3,(H,33,39)
• InChIKey: SQEBSSQXVVTOCI-UHFFFAOYSA-N
• XLogP: 21.48
• TPSA: 449.54 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 32
• Rotatable Bonds: 26
• Heavy Atoms: 166
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2331.17
LogP ≤ 5	21.48
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione?

The IUPAC name of 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione (CID 160906196) is 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione.

What is the SMILES notation for 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione?

The canonical SMILES for 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione is COc1cc(OCCF)ncc1-c1nc2c(n1C(C)C)C1(C(=O)Nc3cc(C)ccc31)N(c1cc(Cl)cnc1C)C2=O.COc1nc(C(C)C)ncc1-c1nc2c(n1C(C)C)C1(C(=O)Nc3cc(C)ccc31)N(c1cc(Cl)ccc1C)C2=O.COc1nc(OCCF)ncc1-c1nc2c(n1C(C)C)C1(C(=O)Nc3cc(C)ccc31)N(c1cc(Cl)cnc1C)C2=O.COc1nc(OCCF)ncc1-c1nc2c(n1C(C)C)C1(C(=O)Nc3cc(C)ccc31)N(c1cccc(Cl)c1)C2=O.

What is the InChIKey of 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione?

The InChIKey is SQEBSSQXVVTOCI-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H31ClN6O3.C30H28ClFN6O4.C29H27ClFN7O4.C29H26ClFN6O4/c1-15(2)26-33-14-20(28(36-26)41-7)27-35-24-25(37(27)16(3)4)31(21-11-8-17(5)12-22(21)34-30(31)40)38(29(24)39)23-13-19(32)10-9-18(23)6;1-15(2)37-26-25(36-27(37)19-14-34-24(42-9-8-32)12-23(19)41-5)28(39)38(22-11-18(31)13-33-17(22)4)30(26)20-7-6-16(3)10-21(20)35-29(30)40;1-14(2)37-23-22(35-24(37)18-13-33-28(42-9-8-31)36-25(18)41-5)26(39)38(21-11-17(30)12-32-16(21)4)29(23)19-7-6-15(3)10-20(19)34-27(29)40;1-15(2)36-23-22(34-24(36)19-14-32-28(41-11-10-31)35-25(19)40-4)26(38)37(18-7-5-6-17(30)13-18)29(23)20-9-8-16(3)12-21(20)33-27(29)39/h8-16H,1-7H3,(H,34,40);6-7,10-15H,8-9H2,1-5H3,(H,35,40);6-7,10-14H,8-9H2,1-5H3,(H,34,40);5-9,12-15H,10-11H2,1-4H3,(H,33,39).

What are the key properties of 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione?

5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione has a molecular weight of 2331.17 g/mol, XLogP of 21.48, 26 rotatable bonds, 4 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 5'-(5-chloro-2-methylphenyl)-2'-(4-methoxy-2-propan-2-ylpyrimidin-5-yl)-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[6-(2-fluoroethoxy)-4-methoxy-3-pyridinyl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(5-chloro-2-methyl-3-pyridinyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione;5'-(3-chlorophenyl)-2'-[2-(2-fluoroethoxy)-4-methoxypyrimidin-5-yl]-6-methyl-3'-propan-2-ylspiro[1H-indole-3,4'-pyrrolo[3,4-d]imidazole]-2,6'-dione is sourced from PubChem (CID 160906196), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).