N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide

C136H120ClF18N23O17 — CID 160909338

IUPACN-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
SMILESC#Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N(C)CCO)c1.C#Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2N(C)CCO)c1.CCCNc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccnc1.CCN(CCO)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccc(C#N)c1.CCN(CCO)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccc(F)c1.CCN(CCO)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccnc1
InChIInChI=1S/C24H21F3N4O3.C23H19ClF2N4O3.C23H21F4N3O3.C23H19F3N4O3.C22H21F3N4O3.C21H19F3N4O2/c1-2-31(10-11-32)22-21(17-5-3-4-16(12-17)14-28)13-18(15-29-22)23(33)30-19-6-8-20(9-7-19)34-24(25,26)27;1-3-15-10-16(13-27-12-15)20-11-17(14-28-21(20)30(2)8-9-31)22(32)29-18-4-6-19(7-5-18)33-23(24,25)26;1-2-30(10-11-31)21-20(15-4-3-5-17(24)12-15)13-16(14-28-21)22(32)29-18-6-8-19(9-7-18)33-23(25,26)27;1-3-15-10-16(13-27-12-15)20-11-17(14-28-21(20)30(2)8-9-31)22(32)29-18-4-6-19(7-5-18)33-23(24,25)26;1-2-29(10-11-30)20-19(15-4-3-9-26-13-15)12-16(14-27-20)21(31)28-17-5-7-18(8-6-17)32-22(23,24)25;1-2-9-26-19-18(14-4-3-10-25-12-14)11-15(13-27-19)20(29)28-16-5-7-17(8-6-16)30-21(22,23)24/h3-9,12-13,15,32H,2,10-11H2,1H3,(H,30,33);1,4-7,10-14,31H,8-9H2,2H3,(H,29,32);3-9,12-14,31H,2,10-11H2,1H3,(H,29,32);1,4-7,10-14,31H,8-9H2,2H3,(H,29,32);3-9,12-14,30H,2,10-11H2,1H3,(H,28,31);3-8,10-13H,2,9H2,1H3,(H,26,27)(H,28,29)
InChIKeySQOIINULLZOSJE-UHFFFAOYSA-N
MW2726.02 g/mol
LogP26.35
Rot. Bonds46

About N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide

N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide (PubChem CID 160909338) has the molecular formula C136H120ClF18N23O17 and a molecular weight of 2726.02 g/mol. Its IUPAC name is N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide.

Molecular Properties

Compound NameN-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
PubChem CID160909338
Molecular FormulaC136H120ClF18N23O17
Molecular Weight2726.02 g/mol
Exact Mass2723.86
IUPAC NameN-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
SMILESC#Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N(C)CCO)c1.C#Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2N(C)CCO)c1.CCCNc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccnc1.CCN(CCO)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccc(C#N)c1.CCN(CCO)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccc(F)c1.CCN(CCO)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccnc1
InChIInChI=1S/C24H21F3N4O3.C23H19ClF2N4O3.C23H21F4N3O3.C23H19F3N4O3.C22H21F3N4O3.C21H19F3N4O2/c1-2-31(10-11-32)22-21(17-5-3-4-16(12-17)14-28)13-18(15-29-22)23(33)30-19-6-8-20(9-7-19)34-24(25,26)27;1-3-15-10-16(13-27-12-15)20-11-17(14-28-21(20)30(2)8-9-31)22(32)29-18-4-6-19(7-5-18)33-23(24,25)26;1-2-30(10-11-31)21-20(15-4-3-5-17(24)12-15)13-16(14-28-21)22(32)29-18-6-8-19(9-7-18)33-23(25,26)27;1-3-15-10-16(13-27-12-15)20-11-17(14-28-21(20)30(2)8-9-31)22(32)29-18-4-6-19(7-5-18)33-23(24,25)26;1-2-29(10-11-30)20-19(15-4-3-9-26-13-15)12-16(14-27-20)21(31)28-17-5-7-18(8-6-17)32-22(23,24)25;1-2-9-26-19-18(14-4-3-10-25-12-14)11-15(13-27-19)20(29)28-16-5-7-17(8-6-16)30-21(22,23)24/h3-9,12-13,15,32H,2,10-11H2,1H3,(H,30,33);1,4-7,10-14,31H,8-9H2,2H3,(H,29,32);3-9,12-14,31H,2,10-11H2,1H3,(H,29,32);1,4-7,10-14,31H,8-9H2,2H3,(H,29,32);3-9,12-14,30H,2,10-11H2,1H3,(H,28,31);3-8,10-13H,2,9H2,1H3,(H,26,27)(H,28,29)
InChIKeySQOIINULLZOSJE-UHFFFAOYSA-N
XLogP26.35
TPSA512.05 Ų
H-Bond Donors12
H-Bond Acceptors34
Rotatable Bonds46
Heavy Atoms195
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002726.02
LogP ≤ 526.35
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1034

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'alkyl_halide', 'substructure': 'N/A'}, {'alert_name': 'triple_bond', 'substructure': 'N/A'}

Analyze N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide with MolForge

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Related Compounds

(R)-N-(4-(Chlorodifluoromethoxy)phenyl)-5-(5-cyano-2-fluorophenyl)-6-(3-hydroxypyrrolidin-1-yl)nicotinamide
CID 89908251
N-(4-(Chlorodifluoromethoxy)phenyl)-5'-cyano-2-(ethyl(2-hydroxyethyl)amino)-[3,3'-bipyridine]-5-carboxamide
CID 118195139
N-(4-(Chlorodifluoromethoxy)phenyl)-5'-cyano-2-((2-hydroxyethyl)(methyl)amino)-[3,3'-bipyridine]-5-carboxamide
CID 118195256
N-(4-(Chlorodifluoromethoxy)phenyl)-2-(ethyl(2-hydroxyethyl)amino)-5'-fluoro-[3,3'-bipyridine]-5-carboxamide
CID 118195301
5'-Fluoro-2-((2-hydroxyethyl)(methyl)amino)-N-(4-(trifluoromethoxy)phenyl)-[3,3'-bipyridine]-5-carboxamide
CID 118195319
N-(4-(Chlorodifluoromethoxy)phenyl)-5'-fluoro-2-((2-hydroxyethyl)(methyl)amino)-[3,3'-bipyridine]-5-carboxamide
CID 118195361
N-[4-[chloro(difluoro)methoxy]phenyl]-5-(4-cyanopyridin-3-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide
CID 118198902
5'-Cyano-2-(ethyl(2-hydroxyethyl)amino)-N-(4-(trifluoromethoxy)phenyl)-[3,3'-bipyridine]-5-carboxamide
CID 118195111
5'-Cyano-2-((2-hydroxyethyl)(methyl)amino)-N-(4-(trifluoromethoxy)phenyl)-[3,3'-bipyridine]-5-carboxamide
CID 118195216
2-(Ethyl(2-hydroxyethyl)amino)-5'-fluoro-N-(4-(trifluoromethoxy)phenyl)-[3,3'-bipyridine]-5-carboxamide
CID 118195377
(R)-N-(4-(Chlorodifluoromethoxy)phenyl)-5-(3-cyano-5-fluorophenyl)-6-(3-hydroxypyrrolidin-1-yl)nicotinamide
CID 89907725
N-[4-[chloro(difluoro)methoxy]phenyl]-5-(3-cyano-5-fluorophenyl)-6-(3-hydroxypyrrolidin-1-yl)pyridine-3-carboxamide
CID 89907727

Frequently Asked Questions

What is the IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide?
The IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide (CID 160909338) is N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide.
What is the SMILES notation for N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide?
The canonical SMILES for N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide is C#Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N(C)CCO)c1.C#Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2N(C)CCO)c1.CCCNc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccnc1.CCN(CCO)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccc(C#N)c1.CCN(CCO)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccc(F)c1.CCN(CCO)c1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccnc1.
What is the InChIKey of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide?
The InChIKey is SQOIINULLZOSJE-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H21F3N4O3.C23H19ClF2N4O3.C23H21F4N3O3.C23H19F3N4O3.C22H21F3N4O3.C21H19F3N4O2/c1-2-31(10-11-32)22-21(17-5-3-4-16(12-17)14-28)13-18(15-29-22)23(33)30-19-6-8-20(9-7-19)34-24(25,26)27;1-3-15-10-16(13-27-12-15)20-11-17(14-28-21(20)30(2)8-9-31)22(32)29-18-4-6-19(7-5-18)33-23(24,25)26;1-2-30(10-11-31)21-20(15-4-3-5-17(24)12-15)13-16(14-28-21)22(32)29-18-6-8-19(9-7-18)33-23(25,26)27;1-3-15-10-16(13-27-12-15)20-11-17(14-28-21(20)30(2)8-9-31)22(32)29-18-4-6-19(7-5-18)33-23(24,25)26;1-2-29(10-11-30)20-19(15-4-3-9-26-13-15)12-16(14-27-20)21(31)28-17-5-7-18(8-6-17)32-22(23,24)25;1-2-9-26-19-18(14-4-3-10-25-12-14)11-15(13-27-19)20(29)28-16-5-7-17(8-6-16)30-21(22,23)24/h3-9,12-13,15,32H,2,10-11H2,1H3,(H,30,33);1,4-7,10-14,31H,8-9H2,2H3,(H,29,32);3-9,12-14,31H,2,10-11H2,1H3,(H,29,32);1,4-7,10-14,31H,8-9H2,2H3,(H,29,32);3-9,12-14,30H,2,10-11H2,1H3,(H,28,31);3-8,10-13H,2,9H2,1H3,(H,26,27)(H,28,29).
What are the key properties of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide?
N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide has a molecular weight of 2726.02 g/mol, XLogP of 26.35, 46 rotatable bonds, 12 hydrogen bond donors, and 34 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]pyridine-3-carboxamide;5-(3-cyanophenyl)-6-[ethyl(2-hydroxyethyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-(3-fluorophenyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[ethyl(2-hydroxyethyl)amino]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-ethynyl-3-pyridinyl)-6-[2-hydroxyethyl(methyl)amino]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(propylamino)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide is sourced from PubChem (CID 160909338), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).