2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine

C83H63ClF10N20O3 — CID 160956276

About 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine

2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine (PubChem CID 160956276) has the molecular formula C83H63ClF10N20O3 and a molecular weight of 1613.99 g/mol. Its IUPAC name is 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine.

Molecular Properties

• Compound Name: 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine
• PubChem CID: 160956276
• Molecular Formula: C83H63ClF10N20O3
• Molecular Weight: 1613.99 g/mol
• Exact Mass: 1612.49
• IUPAC Name: 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine
• SMILES: CCc1cccc2c(Nc3cc(C)[nH]n3)nc(-c3ccccc3OC(F)(F)F)nc12.Cc1cc(Nc2nc(-c3ccccc3Cl)nc3ccccc23)n[nH]1.Cc1cccc2c(Nc3cc(-c4ccco4)[nH]n3)nc(-c3ccccc3OC(F)(F)F)nc12.Fc1ccc2[nH]nc(Nc3nc(-c4ccccc4C(F)(F)F)nc4c3CCC4)c2c1
• InChI: InChI=1S/C23H16F3N5O2.C21H15F4N5.C21H18F3N5O.C18H14ClN5/c1-13-6-4-8-15-20(13)28-21(14-7-2-3-9-17(14)33-23(24,25)26)29-22(15)27-19-12-16(30-31-19)18-10-5-11-32-18;22-11-8-9-17-14(10-11)20(30-29-17)28-19-13-5-3-7-16(13)26-18(27-19)12-4-1-2-6-15(12)21(23,24)25;1-3-13-7-6-9-15-18(13)26-19(27-20(15)25-17-11-12(2)28-29-17)14-8-4-5-10-16(14)30-21(22,23)24;1-11-10-16(24-23-11)21-18-13-7-3-5-9-15(13)20-17(22-18)12-6-2-4-8-14(12)19/h2-12H,1H3,(H2,27,28,29,30,31);1-2,4,6,8-10H,3,5,7H2,(H2,26,27,28,29,30);4-11H,3H2,1-2H3,(H2,25,26,27,28,29);2-10H,1H3,(H2,20,21,22,23,24)
• InChIKey: SWKVFQRMWRBBSY-UHFFFAOYSA-N
• XLogP: 21.90
• TPSA: 297.56 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 19
• Rotatable Bonds: 16
• Heavy Atoms: 117
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1613.99
LogP ≤ 5	21.90
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	19

Frequently Asked Questions

What is the IUPAC name of 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine?

The IUPAC name of 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine (CID 160956276) is 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine.

What is the SMILES notation for 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine?

The canonical SMILES for 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine is CCc1cccc2c(Nc3cc(C)[nH]n3)nc(-c3ccccc3OC(F)(F)F)nc12.Cc1cc(Nc2nc(-c3ccccc3Cl)nc3ccccc23)n[nH]1.Cc1cccc2c(Nc3cc(-c4ccco4)[nH]n3)nc(-c3ccccc3OC(F)(F)F)nc12.Fc1ccc2[nH]nc(Nc3nc(-c4ccccc4C(F)(F)F)nc4c3CCC4)c2c1.

What is the InChIKey of 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine?

The InChIKey is SWKVFQRMWRBBSY-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H16F3N5O2.C21H15F4N5.C21H18F3N5O.C18H14ClN5/c1-13-6-4-8-15-20(13)28-21(14-7-2-3-9-17(14)33-23(24,25)26)29-22(15)27-19-12-16(30-31-19)18-10-5-11-32-18;22-11-8-9-17-14(10-11)20(30-29-17)28-19-13-5-3-7-16(13)26-18(27-19)12-4-1-2-6-15(12)21(23,24)25;1-3-13-7-6-9-15-18(13)26-19(27-20(15)25-17-11-12(2)28-29-17)14-8-4-5-10-16(14)30-21(22,23)24;1-11-10-16(24-23-11)21-18-13-7-3-5-9-15(13)20-17(22-18)12-6-2-4-8-14(12)19/h2-12H,1H3,(H2,27,28,29,30,31);1-2,4,6,8-10H,3,5,7H2,(H2,26,27,28,29,30);4-11H,3H2,1-2H3,(H2,25,26,27,28,29);2-10H,1H3,(H2,20,21,22,23,24).

What are the key properties of 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine?

2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine has a molecular weight of 1613.99 g/mol, XLogP of 21.90, 16 rotatable bonds, 8 hydrogen bond donors, and 19 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(2-chlorophenyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine;8-ethyl-N-(5-methyl-1H-pyrazol-3-yl)-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine;5-fluoro-N-[2-[2-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1H-indazol-3-amine;N-[5-(furan-2-yl)-1H-pyrazol-3-yl]-8-methyl-2-[2-(trifluoromethoxy)phenyl]quinazolin-4-amine is sourced from PubChem (CID 160956276), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).