2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide

C129H127F16N53O11 — CID 160982259

IUPAC2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide
SMILESCN(C)C(=O)c1cnc(N2CCN(c3nc4c(C(N)=O)cc(F)cc4[nH]3)CC2)cn1.N#Cc1cnc(N2CCN(c3nc4c(C(N)=O)cc(F)cc4[nH]3)CC2)cn1.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4ccc(C(F)(F)F)nn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(=O)N5CCCC5)cn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(=O)N5CCOCC5)cn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(F)(F)F)cn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(F)(F)F)nc4)CC3)nc12
InChIInChI=1S/C21H23FN8O3.C21H23FN8O2.C19H21FN8O2.3C17H15F4N7O.C17H15FN8O/c22-13-9-14(19(23)31)18-15(10-13)26-21(27-18)30-3-1-28(2-4-30)17-12-24-16(11-25-17)20(32)29-5-7-33-8-6-29;22-13-9-14(19(23)31)18-15(10-13)26-21(27-18)30-7-5-28(6-8-30)17-12-24-16(11-25-17)20(32)29-3-1-2-4-29;1-26(2)18(30)14-9-23-15(10-22-14)27-3-5-28(6-4-27)19-24-13-8-11(20)7-12(17(21)29)16(13)25-19;18-9-5-11(14(22)29)13-12(6-9)25-16(26-13)28-3-1-27(2-4-28)10-7-23-15(24-8-10)17(19,20)21;18-9-5-10(15(22)29)14-11(6-9)25-16(26-14)28-3-1-27(2-4-28)13-8-23-12(7-24-13)17(19,20)21;18-9-7-10(15(22)29)14-11(8-9)23-16(24-14)28-5-3-27(4-6-28)13-2-1-12(25-26-13)17(19,20)21;18-10-5-12(16(20)27)15-13(6-10)23-17(24-15)26-3-1-25(2-4-26)14-9-21-11(7-19)8-22-14/h9-12H,1-8H2,(H2,23,31)(H,26,27);9-12H,1-8H2,(H2,23,31)(H,26,27);7-10H,3-6H2,1-2H3,(H2,21,29)(H,24,25);2*5-8H,1-4H2,(H2,22,29)(H,25,26);1-2,7-8H,3-6H2,(H2,22,29)(H,23,24);5-6,8-9H,1-4H2,(H2,20,27)(H,23,24)
InChIKeySZQZWGSHUDPVLE-UHFFFAOYSA-N
MW2899.76 g/mol
LogP8.76
Rot. Bonds24

About 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide

2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide (PubChem CID 160982259) has the molecular formula C129H127F16N53O11 and a molecular weight of 2899.76 g/mol. Its IUPAC name is 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide.

Molecular Properties

Compound Name2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide
PubChem CID160982259
Molecular FormulaC129H127F16N53O11
Molecular Weight2899.76 g/mol
Exact Mass2898.08
IUPAC Name2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide
SMILESCN(C)C(=O)c1cnc(N2CCN(c3nc4c(C(N)=O)cc(F)cc4[nH]3)CC2)cn1.N#Cc1cnc(N2CCN(c3nc4c(C(N)=O)cc(F)cc4[nH]3)CC2)cn1.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4ccc(C(F)(F)F)nn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(=O)N5CCCC5)cn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(=O)N5CCOCC5)cn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(F)(F)F)cn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(F)(F)F)nc4)CC3)nc12
InChIInChI=1S/C21H23FN8O3.C21H23FN8O2.C19H21FN8O2.3C17H15F4N7O.C17H15FN8O/c22-13-9-14(19(23)31)18-15(10-13)26-21(27-18)30-3-1-28(2-4-30)17-12-24-16(11-25-17)20(32)29-5-7-33-8-6-29;22-13-9-14(19(23)31)18-15(10-13)26-21(27-18)30-7-5-28(6-8-30)17-12-24-16(11-25-17)20(32)29-3-1-2-4-29;1-26(2)18(30)14-9-23-15(10-22-14)27-3-5-28(6-4-27)19-24-13-8-11(20)7-12(17(21)29)16(13)25-19;18-9-5-11(14(22)29)13-12(6-9)25-16(26-13)28-3-1-27(2-4-28)10-7-23-15(24-8-10)17(19,20)21;18-9-5-10(15(22)29)14-11(6-9)25-16(26-14)28-3-1-27(2-4-28)13-8-23-12(7-24-13)17(19,20)21;18-9-7-10(15(22)29)14-11(8-9)23-16(24-14)28-5-3-27(4-6-28)13-2-1-12(25-26-13)17(19,20)21;18-10-5-12(16(20)27)15-13(6-10)23-17(24-15)26-3-1-25(2-4-26)14-9-21-11(7-19)8-22-14/h9-12H,1-8H2,(H2,23,31)(H,26,27);9-12H,1-8H2,(H2,23,31)(H,26,27);7-10H,3-6H2,1-2H3,(H2,21,29)(H,24,25);2*5-8H,1-4H2,(H2,22,29)(H,25,26);1-2,7-8H,3-6H2,(H2,22,29)(H,23,24);5-6,8-9H,1-4H2,(H2,20,27)(H,23,24)
InChIKeySZQZWGSHUDPVLE-UHFFFAOYSA-N
XLogP8.76
TPSA822.16 Ų
H-Bond Donors14
H-Bond Acceptors47
Rotatable Bonds24
Heavy Atoms209
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002899.76
LogP ≤ 58.76
H-Bond Donors ≤ 514
H-Bond Acceptors ≤ 1047

Analyze 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

4-amino-6-[[(1S)-1-[6-fluoro-7-(morpholine-4-carbonyl)-1-phenylbenzimidazol-2-yl]ethyl]amino]-2-[[(1S)-1-(6-fluoro-1-phenylbenzimidazol-2-yl)ethyl]-pyrido[3,2-d]pyrimidin-4-ylamino]pyrimidine-5-carbonitrile
CID 68280016
N-[3-(difluoromethyl)-1-[4-[9-[[1-(2,6-dioxopiperidin-3-yl)-3-methyl-2-oxobenzimidazol-4-yl]methyl]-3,9-diazaspiro[5.5]undecane-3-carbonyl]cyclohexyl]pyrazol-4-yl]-5-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157125399
5-(5-amino-3-pyridinyl)-N-[6-(dimethylamino)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(dimethylamino)-3-pyridinyl]-1H-indole-3-carboxamide;N-[6-(dimethylamino)-3-pyridinyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[6-(dimethylamino)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;ethoxyethane
CID 157154090
2-(azetidin-1-yl)-4-fluoro-5-propan-2-ylpyridine;2-(azetidin-1-yl)-5-propan-2-ylpyridine;2-(azetidin-1-yl)-5-propan-2-yl-3-(trifluoromethyl)pyridine;5-fluoro-6-propan-2-ylpyridine-3-carboxamide;4-(3-fluoro-5-propan-2-yl-2-pyridinyl)morpholine;3-fluoro-5-propan-2-yl-1H-pyrrolo[2,3-b]pyridine;5-methyl-6-propan-2-ylpyridine-3-carboxamide;4-(3-methyl-5-propan-2-yl-2-pyridinyl)morpholine;1-methyl-5-propan-2-ylpyrrolo[2,3-b]pyridine;5-propan-2-yl-2,4-bis(trifluoromethyl)pyridine;4-propan-2-yl-1,3-dihydroindol-2-one;1-(3-propan-2-ylindol-1-yl)ethanone;5-propan-2-yl-2-pyridazin-4-ylpyrimidine;3-propan-2-ylpyridine-4-carbonitrile;4-(5-propan-2-ylpyrimidin-2-yl)-1H-pyridin-2-one;4-propan-2-yl-1H-pyrrolo[2,3-c]pyridine
CID 157184130
[4-[8-tert-butyl-6-[4-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-(1H-pyrazol-5-yl)methanone;[4-[8-tert-butyl-6-[4-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-pyridin-2-ylmethanone;[8-tert-butyl-6-[4-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-2-yl]-[2,2-dimethyl-4-(5-methyl-1,3,4-oxadiazole-2-carbonyl)piperazin-1-yl]methanone;[8-tert-butyl-6-[4-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-2-yl]-[2,2-dimethyl-4-(pyrimidine-2-carbonyl)piperazin-1-yl]methanone
CID 157192282
5-[2-(3-cyclopropylphenyl)-3-pyridinyl]-1-methylbenzimidazole;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]-1-methylbenzimidazole;[5-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-1H-indazol-7-yl]-morpholin-4-ylmethanone;6-[2-[3-(trifluoromethyl)phenyl]-3-pyridinyl]imidazo[1,2-a]pyridine;5-[2-[3-(trifluoromethyl)phenyl]-3-pyridinyl]-1H-indazole;5-[2-[3-(trifluoromethyl)phenyl]-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine
CID 157192628
[4-[8-tert-butyl-6-(4-methylphenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-pyridin-2-ylmethanone;[3,3-dimethyl-4-[8-propan-2-yl-6-[4-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazine-2-carbonyl]piperazin-1-yl]-(5-methyl-1H-pyrazol-3-yl)methanone;4-[6-(4-fluoro-3-methylphenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-(2-methyl-1H-imidazol-5-yl)piperazin-2-one;4-[6-(4-fluoro-3-methylphenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-(3H-pyrrol-5-yl)piperazin-2-one
CID 157222251
1H-indol-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;tetrakis((6-methyl-1H-pyrrolo[3,2-b]pyridin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);1H-pyrrolo[2,3-b]pyridin-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1H-pyrrolo[3,2-b]pyridin-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1H-pyrrolo[2,3-c]pyridin-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 157255418
1H-benzimidazol-2-yl-[2-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-7-azabicyclo[2.2.1]heptan-7-yl]methanone;[3-fluoro-2-(triazol-2-yl)phenyl]-[2-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-7-azabicyclo[2.2.1]heptan-7-yl]methanone;(1-methylbenzimidazol-2-yl)-[2-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-7-azabicyclo[2.2.1]heptan-7-yl]methanone
CID 157255986
N-[3-(difluoromethyl)-1-[1-[4-[3-[1-(2,4-dioxocyclohexyl)-3-methyl-2-oxobenzimidazol-4-yl]propyl-methylcarbamoyl]phenyl]piperidin-4-yl]pyrazol-4-yl]-5-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157258070
2-[[4-[5-amino-6-(3-aminopropyl)pyrazin-2-yl]phenyl]methylamino]-5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide;3-[[4-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)phenyl]methylamino]-6-cyano-N-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrazine-2-carboxamide;3-[[4-(3-amino-2H-pyrazolo[3,4-b]pyridin-5-yl)phenyl]methylamino]-6-cyano-N-[(1S)-1-(3-fluoro-4-methylphenyl)ethyl]pyrazine-2-carboxamide;2-[[4-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]methylamino]-5-cyano-N-[(1S)-1-(4-methylphenyl)ethyl]pyridine-3-carboxamide;2-[[4-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]methylamino]-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-3-carboxamide
CID 157291192
1-[(2S)-4-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]-2-methylpiperazin-1-yl]-2-phenylethanone;[(2S)-4-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]-2-methylpiperazin-1-yl]-phenylmethanone;[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]-[(3S)-4-(1H-imidazole-2-carbonyl)-3-methylpiperazin-1-yl]methanone
CID 157328934

Frequently Asked Questions

What is the IUPAC name of 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide?
The IUPAC name of 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide (CID 160982259) is 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide.
What is the SMILES notation for 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide?
The canonical SMILES for 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide is CN(C)C(=O)c1cnc(N2CCN(c3nc4c(C(N)=O)cc(F)cc4[nH]3)CC2)cn1.N#Cc1cnc(N2CCN(c3nc4c(C(N)=O)cc(F)cc4[nH]3)CC2)cn1.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4ccc(C(F)(F)F)nn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(=O)N5CCCC5)cn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(=O)N5CCOCC5)cn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(F)(F)F)cn4)CC3)nc12.NC(=O)c1cc(F)cc2[nH]c(N3CCN(c4cnc(C(F)(F)F)nc4)CC3)nc12.
What is the InChIKey of 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide?
The InChIKey is SZQZWGSHUDPVLE-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H23FN8O3.C21H23FN8O2.C19H21FN8O2.3C17H15F4N7O.C17H15FN8O/c22-13-9-14(19(23)31)18-15(10-13)26-21(27-18)30-3-1-28(2-4-30)17-12-24-16(11-25-17)20(32)29-5-7-33-8-6-29;22-13-9-14(19(23)31)18-15(10-13)26-21(27-18)30-7-5-28(6-8-30)17-12-24-16(11-25-17)20(32)29-3-1-2-4-29;1-26(2)18(30)14-9-23-15(10-22-14)27-3-5-28(6-4-27)19-24-13-8-11(20)7-12(17(21)29)16(13)25-19;18-9-5-11(14(22)29)13-12(6-9)25-16(26-13)28-3-1-27(2-4-28)10-7-23-15(24-8-10)17(19,20)21;18-9-5-10(15(22)29)14-11(6-9)25-16(26-14)28-3-1-27(2-4-28)13-8-23-12(7-24-13)17(19,20)21;18-9-7-10(15(22)29)14-11(8-9)23-16(24-14)28-5-3-27(4-6-28)13-2-1-12(25-26-13)17(19,20)21;18-10-5-12(16(20)27)15-13(6-10)23-17(24-15)26-3-1-25(2-4-26)14-9-21-11(7-19)8-22-14/h9-12H,1-8H2,(H2,23,31)(H,26,27);9-12H,1-8H2,(H2,23,31)(H,26,27);7-10H,3-6H2,1-2H3,(H2,21,29)(H,24,25);2*5-8H,1-4H2,(H2,22,29)(H,25,26);1-2,7-8H,3-6H2,(H2,22,29)(H,23,24);5-6,8-9H,1-4H2,(H2,20,27)(H,23,24).
What are the key properties of 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide?
2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide has a molecular weight of 2899.76 g/mol, XLogP of 8.76, 24 rotatable bonds, 14 hydrogen bond donors, and 47 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-(5-cyanopyrazin-2-yl)piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;2-[4-[5-(dimethylcarbamoyl)pyrazin-2-yl]piperazin-1-yl]-6-fluoro-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(morpholine-4-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(pyrrolidine-1-carbonyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide;6-fluoro-2-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]-1H-benzimidazole-4-carboxamide is sourced from PubChem (CID 160982259), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).