N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine

C94H91N39OS14 — CID 160984129

About N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine

N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine (PubChem CID 160984129) has the molecular formula C94H91N39OS14 and a molecular weight of 2231.97 g/mol. Its IUPAC name is N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine.

Molecular Properties

• Compound Name: N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine
• PubChem CID: 160984129
• Molecular Formula: C94H91N39OS14
• Molecular Weight: 2231.97 g/mol
• Exact Mass: 2229.44
• IUPAC Name: N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine
• SMILES: CNc1ncc(-c2cnc3c(Nc4cc(C)ns4)nc(SC)cn23)s1.CSc1cn2c(-c3cc(C4CC4)[nH]n3)cnc2c(Nc2cc(C)ns2)n1.CSc1cn2c(-c3ccco3)cnc2c(Nc2cc(C)ns2)n1.CSc1cn2c(-c3ccn[nH]3)cnc2c(Nc2cc(C)ns2)n1.CSc1cn2c(-c3ccsc3)cnc2c(Nc2cc(C)ns2)n1.Cc1cc(Nc2nc(SC3CCNC3)cn3c(-c4cnn(C)c4)cnc23)sn1
• InChI: InChI=1S/C18H20N8S2.C17H17N7S2.C15H15N7S3.C15H13N5OS2.C15H13N5S3.C14H13N7S2/c1-11-5-15(28-24-11)22-17-18-20-8-14(12-6-21-25(2)9-12)26(18)10-16(23-17)27-13-3-4-19-7-13;1-9-5-14(26-23-9)19-16-17-18-7-13(24(17)8-15(20-16)25-2)12-6-11(21-22-12)10-3-4-10;1-8-4-11(25-21-8)19-13-14-17-5-9(10-6-18-15(16-2)24-10)22(14)7-12(20-13)23-3;1-9-6-12(23-19-9)17-14-15-16-7-10(11-4-3-5-21-11)20(15)8-13(18-14)22-2;1-9-5-12(23-19-9)17-14-15-16-6-11(10-3-4-22-8-10)20(15)7-13(18-14)21-2;1-8-5-11(23-20-8)17-13-14-15-6-10(9-3-4-16-19-9)21(14)7-12(18-13)22-2/h5-6,8-10,13,19H,3-4,7H2,1-2H3,(H,22,23);5-8,10H,3-4H2,1-2H3,(H,19,20)(H,21,22);4-7H,1-3H3,(H,16,18)(H,19,20);2*3-8H,1-2H3,(H,17,18);3-7H,1-2H3,(H,16,19)(H,17,18)
• InChIKey: SZWYIEUYEJKTSC-UHFFFAOYSA-N
• XLogP: 23.70
• TPSA: 455.93 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 52
• Rotatable Bonds: 27
• Heavy Atoms: 148
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2231.97
LogP ≤ 5	23.70
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	52

Frequently Asked Questions

What is the IUPAC name of N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine?

The IUPAC name of N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine (CID 160984129) is N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine.

What is the SMILES notation for N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine?

The canonical SMILES for N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine is CNc1ncc(-c2cnc3c(Nc4cc(C)ns4)nc(SC)cn23)s1.CSc1cn2c(-c3cc(C4CC4)[nH]n3)cnc2c(Nc2cc(C)ns2)n1.CSc1cn2c(-c3ccco3)cnc2c(Nc2cc(C)ns2)n1.CSc1cn2c(-c3ccn[nH]3)cnc2c(Nc2cc(C)ns2)n1.CSc1cn2c(-c3ccsc3)cnc2c(Nc2cc(C)ns2)n1.Cc1cc(Nc2nc(SC3CCNC3)cn3c(-c4cnn(C)c4)cnc23)sn1.

What is the InChIKey of N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine?

The InChIKey is SZWYIEUYEJKTSC-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H20N8S2.C17H17N7S2.C15H15N7S3.C15H13N5OS2.C15H13N5S3.C14H13N7S2/c1-11-5-15(28-24-11)22-17-18-20-8-14(12-6-21-25(2)9-12)26(18)10-16(23-17)27-13-3-4-19-7-13;1-9-5-14(26-23-9)19-16-17-18-7-13(24(17)8-15(20-16)25-2)12-6-11(21-22-12)10-3-4-10;1-8-4-11(25-21-8)19-13-14-17-5-9(10-6-18-15(16-2)24-10)22(14)7-12(20-13)23-3;1-9-6-12(23-19-9)17-14-15-16-7-10(11-4-3-5-21-11)20(15)8-13(18-14)22-2;1-9-5-12(23-19-9)17-14-15-16-6-11(10-3-4-22-8-10)20(15)7-13(18-14)21-2;1-8-5-11(23-20-8)17-13-14-15-6-10(9-3-4-16-19-9)21(14)7-12(18-13)22-2/h5-6,8-10,13,19H,3-4,7H2,1-2H3,(H,22,23);5-8,10H,3-4H2,1-2H3,(H,19,20)(H,21,22);4-7H,1-3H3,(H,16,18)(H,19,20);2*3-8H,1-2H3,(H,17,18);3-7H,1-2H3,(H,16,19)(H,17,18).

What are the key properties of N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine?

N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine has a molecular weight of 2231.97 g/mol, XLogP of 23.70, 27 rotatable bonds, 10 hydrogen bond donors, and 52 hydrogen bond acceptors.

Where does this data come from?

All data for N-[3-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;N-[3-(furan-2-yl)-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine;3-methyl-N-[3-[2-(methylamino)-1,3-thiazol-5-yl]-6-methylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[3-(1-methylpyrazol-4-yl)-6-pyrrolidin-3-ylsulfanylimidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-[6-methylsulfanyl-3-(1H-pyrazol-5-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2-thiazol-5-amine;3-methyl-N-(6-methylsulfanyl-3-thiophen-3-ylimidazo[1,2-a]pyrazin-8-yl)-1,2-thiazol-5-amine is sourced from PubChem (CID 160984129), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).