6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine

C103H77Cl4FN26O3 — CID 160984180

About 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine

6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine (PubChem CID 160984180) has the molecular formula C103H77Cl4FN26O3 and a molecular weight of 1887.74 g/mol. Its IUPAC name is 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine.

Molecular Properties

• Compound Name: 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine
• PubChem CID: 160984180
• Molecular Formula: C103H77Cl4FN26O3
• Molecular Weight: 1887.74 g/mol
• Exact Mass: 1884.54
• IUPAC Name: 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine
• SMILES: CCOC(=O)c1ccc(CC(=O)CCc2nc(-c3ccccc3)c(-c3ccc4ncccc4c3)nc2C#N)cc1.Cc1ccn(-c2nc(N)c(C)nc2-c2cc(Cl)c3ncccc3c2)n1.Cc1nc(-c2ccc3ncccc3c2)c(-c2ccccc2)nc1N.Nc1cnc(-c2cc(Cl)c3ncccc3c2)c(-n2ccc(Cl)n2)n1.Nc1cnc(-c2cc(Cl)c3ncccc3c2)c(-n2ccc(F)n2)n1
• InChI: InChI=1S/C33H26N4O3.C20H16N4.C18H15ClN6.C16H10Cl2N6.C16H10ClFN6/c1-2-40-33(39)24-12-10-22(11-13-24)19-27(38)15-17-29-30(21-34)37-32(31(36-29)23-7-4-3-5-8-23)26-14-16-28-25(20-26)9-6-18-35-28;1-13-20(21)24-18(14-6-3-2-4-7-14)19(23-13)16-9-10-17-15(12-16)8-5-11-22-17;1-10-5-7-25(24-10)18-16(22-11(2)17(20)23-18)13-8-12-4-3-6-21-15(12)14(19)9-13;2*17-11-7-10(6-9-2-1-4-20-14(9)11)15-16(22-13(19)8-21-15)24-5-3-12(18)23-24/h3-14,16,18,20H,2,15,17,19H2,1H3;2-12H,1H3,(H2,21,24);3-9H,1-2H3,(H2,20,23);2*1-8H,(H2,19,22)
• InChIKey: SZXCPPRWNJXZNS-UHFFFAOYSA-N
• XLogP: 21.15
• TPSA: 418.05 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 29
• Rotatable Bonds: 17
• Heavy Atoms: 137
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1887.74
LogP ≤ 5	21.15
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	29

Frequently Asked Questions

What is the IUPAC name of 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine?

The IUPAC name of 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine (CID 160984180) is 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine.

What is the SMILES notation for 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine?

The canonical SMILES for 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine is CCOC(=O)c1ccc(CC(=O)CCc2nc(-c3ccccc3)c(-c3ccc4ncccc4c3)nc2C#N)cc1.Cc1ccn(-c2nc(N)c(C)nc2-c2cc(Cl)c3ncccc3c2)n1.Cc1nc(-c2ccc3ncccc3c2)c(-c2ccccc2)nc1N.Nc1cnc(-c2cc(Cl)c3ncccc3c2)c(-n2ccc(Cl)n2)n1.Nc1cnc(-c2cc(Cl)c3ncccc3c2)c(-n2ccc(F)n2)n1.

What is the InChIKey of 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine?

The InChIKey is SZXCPPRWNJXZNS-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H26N4O3.C20H16N4.C18H15ClN6.C16H10Cl2N6.C16H10ClFN6/c1-2-40-33(39)24-12-10-22(11-13-24)19-27(38)15-17-29-30(21-34)37-32(31(36-29)23-7-4-3-5-8-23)26-14-16-28-25(20-26)9-6-18-35-28;1-13-20(21)24-18(14-6-3-2-4-7-14)19(23-13)16-9-10-17-15(12-16)8-5-11-22-17;1-10-5-7-25(24-10)18-16(22-11(2)17(20)23-18)13-8-12-4-3-6-21-15(12)14(19)9-13;2*17-11-7-10(6-9-2-1-4-20-14(9)11)15-16(22-13(19)8-21-15)24-5-3-12(18)23-24/h3-14,16,18,20H,2,15,17,19H2,1H3;2-12H,1H3,(H2,21,24);3-9H,1-2H3,(H2,20,23);2*1-8H,(H2,19,22).

What are the key properties of 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine?

6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine has a molecular weight of 1887.74 g/mol, XLogP of 21.15, 17 rotatable bonds, 4 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-chloropyrazol-1-yl)-5-(8-chloroquinolin-6-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methyl-6-(3-methylpyrazol-1-yl)pyrazin-2-amine;ethyl 4-[4-(3-cyano-6-phenyl-5-quinolin-6-ylpyrazin-2-yl)-2-oxobutyl]benzoate;3-methyl-6-phenyl-5-quinolin-6-ylpyrazin-2-amine is sourced from PubChem (CID 160984180), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).