N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide

C116H97F8N31O14 — CID 160988183

About N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide

N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide (PubChem CID 160988183) has the molecular formula C116H97F8N31O14 and a molecular weight of 2301.24 g/mol. Its IUPAC name is N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide.

Molecular Properties

• Compound Name: N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide
• PubChem CID: 160988183
• Molecular Formula: C116H97F8N31O14
• Molecular Weight: 2301.24 g/mol
• Exact Mass: 2299.77
• IUPAC Name: N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide
• SMILES: CC(C)(C)Oc1ccccc1C(=O)Nc1cn[nH]c1-c1nc2ccccc2[nH]1.CCOc1ccccc1C(=O)Nc1cn[nH]c1-c1nc2ccccc2[nH]1.COc1cc(F)ccc1C(=O)Nc1cn[nH]c1-c1nc2ccccc2[nH]1.O=C(NCCOCCO)c1ccc2nc(-c3[nH]ncc3NC(=O)c3c(F)cccc3F)[nH]c2c1.O=C(Nc1cn[nH]c1-c1nc2ccccc2[nH]1)c1ccccc1OC(F)(F)F.O=C(Nc1cn[nH]c1-c1nc2ccccc2[nH]1)c1ccccc1OC(F)F
• InChI: InChI=1S/C22H20F2N6O4.C21H21N5O2.C19H17N5O2.C18H12F3N5O2.C18H13F2N5O2.C18H14FN5O2/c23-13-2-1-3-14(24)18(13)22(33)29-17-11-26-30-19(17)20-27-15-5-4-12(10-16(15)28-20)21(32)25-6-8-34-9-7-31;1-21(2,3)28-17-11-7-4-8-13(17)20(27)25-16-12-22-26-18(16)19-23-14-9-5-6-10-15(14)24-19;1-2-26-16-10-6-3-7-12(16)19(25)23-15-11-20-24-17(15)18-21-13-8-4-5-9-14(13)22-18;19-18(20,21)28-14-8-4-1-5-10(14)17(27)25-13-9-22-26-15(13)16-23-11-6-2-3-7-12(11)24-16;19-18(20)27-14-8-4-1-5-10(14)17(26)24-13-9-21-25-15(13)16-22-11-6-2-3-7-12(11)23-16;1-26-15-8-10(19)6-7-11(15)18(25)23-14-9-20-24-16(14)17-21-12-4-2-3-5-13(12)22-17/h1-5,10-11,31H,6-9H2,(H,25,32)(H,26,30)(H,27,28)(H,29,33);4-12H,1-3H3,(H,22,26)(H,23,24)(H,25,27);3-11H,2H2,1H3,(H,20,24)(H,21,22)(H,23,25);1-9H,(H,22,26)(H,23,24)(H,25,27);1-9,18H,(H,21,25)(H,22,23)(H,24,26);2-9H,1H3,(H,20,24)(H,21,22)(H,23,25)
• InChIKey: TUGKUXUYIHWISW-UHFFFAOYSA-N
• XLogP: 21.47
• TPSA: 623.47 Ų
• H-Bond Donors: 20
• H-Bond Acceptors: 26
• Rotatable Bonds: 31
• Heavy Atoms: 169
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2301.24
LogP ≤ 5	21.47
H-Bond Donors ≤ 5	20
H-Bond Acceptors ≤ 10	26

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide?

The IUPAC name of N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide (CID 160988183) is N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide.

What is the SMILES notation for N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide?

The canonical SMILES for N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide is CC(C)(C)Oc1ccccc1C(=O)Nc1cn[nH]c1-c1nc2ccccc2[nH]1.CCOc1ccccc1C(=O)Nc1cn[nH]c1-c1nc2ccccc2[nH]1.COc1cc(F)ccc1C(=O)Nc1cn[nH]c1-c1nc2ccccc2[nH]1.O=C(NCCOCCO)c1ccc2nc(-c3[nH]ncc3NC(=O)c3c(F)cccc3F)[nH]c2c1.O=C(Nc1cn[nH]c1-c1nc2ccccc2[nH]1)c1ccccc1OC(F)(F)F.O=C(Nc1cn[nH]c1-c1nc2ccccc2[nH]1)c1ccccc1OC(F)F.

What is the InChIKey of N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide?

The InChIKey is TUGKUXUYIHWISW-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H20F2N6O4.C21H21N5O2.C19H17N5O2.C18H12F3N5O2.C18H13F2N5O2.C18H14FN5O2/c23-13-2-1-3-14(24)18(13)22(33)29-17-11-26-30-19(17)20-27-15-5-4-12(10-16(15)28-20)21(32)25-6-8-34-9-7-31;1-21(2,3)28-17-11-7-4-8-13(17)20(27)25-16-12-22-26-18(16)19-23-14-9-5-6-10-15(14)24-19;1-2-26-16-10-6-3-7-12(16)19(25)23-15-11-20-24-17(15)18-21-13-8-4-5-9-14(13)22-18;19-18(20,21)28-14-8-4-1-5-10(14)17(27)25-13-9-22-26-15(13)16-23-11-6-2-3-7-12(11)24-16;19-18(20)27-14-8-4-1-5-10(14)17(26)24-13-9-21-25-15(13)16-22-11-6-2-3-7-12(11)23-16;1-26-15-8-10(19)6-7-11(15)18(25)23-14-9-20-24-16(14)17-21-12-4-2-3-5-13(12)22-17/h1-5,10-11,31H,6-9H2,(H,25,32)(H,26,30)(H,27,28)(H,29,33);4-12H,1-3H3,(H,22,26)(H,23,24)(H,25,27);3-11H,2H2,1H3,(H,20,24)(H,21,22)(H,23,25);1-9H,(H,22,26)(H,23,24)(H,25,27);1-9,18H,(H,21,25)(H,22,23)(H,24,26);2-9H,1H3,(H,20,24)(H,21,22)(H,23,25).

What are the key properties of N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide?

N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide has a molecular weight of 2301.24 g/mol, XLogP of 21.47, 31 rotatable bonds, 20 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(difluoromethoxy)benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-ethoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-4-fluoro-2-methoxybenzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-[(2-methylpropan-2-yl)oxy]benzamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-(trifluoromethoxy)benzamide;2-[4-[(2,6-difluorobenzoyl)amino]-1H-pyrazol-5-yl]-N-[2-(2-hydroxyethoxy)ethyl]-3H-benzimidazole-5-carboxamide is sourced from PubChem (CID 160988183), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).