3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine

C86H88F5N39O9S — CID 160997820

About 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine

3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine (PubChem CID 160997820) has the molecular formula C86H88F5N39O9S and a molecular weight of 1938.97 g/mol. Its IUPAC name is 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine.

Molecular Properties

• Compound Name: 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine
• PubChem CID: 160997820
• Molecular Formula: C86H88F5N39O9S
• Molecular Weight: 1938.97 g/mol
• Exact Mass: 1937.73
• IUPAC Name: 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine
• SMILES: CC(=O)N1CCN(c2cccc(-c3cnc4cnc(C(N)=O)cn34)n2)CC1.CC(=O)N1CCN(c2cncc(-c3cnc4cnc(C(N)=O)cn34)n2)CC1.CC(=O)N1CCN(c2nccc(-c3cnc4cnc(C(N)=O)cn34)n2)CC1.FC(F)(F)c1cn2c(-c3ccnc(N4CCOC(c5cn[nH]c5)C4)n3)cnc2cn1.NS(=O)(=O)N[C@@H]1CCCN(c2ccnc(-c3cnc4cnc(C(F)F)cn34)n2)C1
• InChI: InChI=1S/C18H15F3N8O.C18H19N7O2.2C17H18N8O2.C16H18F2N8O2S/c19-18(20,21)15-10-29-13(7-24-16(29)8-23-15)12-1-2-22-17(27-12)28-3-4-30-14(9-28)11-5-25-26-6-11;1-12(26)23-5-7-24(8-6-23)16-4-2-3-13(22-16)15-9-21-17-10-20-14(18(19)27)11-25(15)17;1-11(26)23-2-4-24(5-3-23)16-8-19-6-12(22-16)14-7-21-15-9-20-13(17(18)27)10-25(14)15;1-11(26)23-4-6-24(7-5-23)17-19-3-2-12(22-17)14-8-21-15-9-20-13(16(18)27)10-25(14)15;17-15(18)11-9-26-12(6-22-14(26)7-21-11)16-20-4-3-13(23-16)25-5-1-2-10(8-25)24-29(19,27)28/h1-2,5-8,10,14H,3-4,9H2,(H,25,26);2-4,9-11H,5-8H2,1H3,(H2,19,27);6-10H,2-5H2,1H3,(H2,18,27);2-3,8-10H,4-7H2,1H3,(H2,18,27);3-4,6-7,9-10,15,24H,1-2,5,8H2,(H2,19,27,28)/t;;;;10-/m....1/s1
• InChIKey: TVMBXHZCVPYYKN-FGVGXLIFSA-N
• XLogP: 3.86
• TPSA: 583.46 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 39
• Rotatable Bonds: 17
• Heavy Atoms: 140
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1938.97
LogP ≤ 5	3.86
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	39

Frequently Asked Questions

What is the IUPAC name of 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine?

The IUPAC name of 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine (CID 160997820) is 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine.

What is the SMILES notation for 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine?

The canonical SMILES for 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine is CC(=O)N1CCN(c2cccc(-c3cnc4cnc(C(N)=O)cn34)n2)CC1.CC(=O)N1CCN(c2cncc(-c3cnc4cnc(C(N)=O)cn34)n2)CC1.CC(=O)N1CCN(c2nccc(-c3cnc4cnc(C(N)=O)cn34)n2)CC1.FC(F)(F)c1cn2c(-c3ccnc(N4CCOC(c5cn[nH]c5)C4)n3)cnc2cn1.NS(=O)(=O)N[C@@H]1CCCN(c2ccnc(-c3cnc4cnc(C(F)F)cn34)n2)C1.

What is the InChIKey of 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine?

The InChIKey is TVMBXHZCVPYYKN-FGVGXLIFSA-N. The full InChI is InChI=1S/C18H15F3N8O.C18H19N7O2.2C17H18N8O2.C16H18F2N8O2S/c19-18(20,21)15-10-29-13(7-24-16(29)8-23-15)12-1-2-22-17(27-12)28-3-4-30-14(9-28)11-5-25-26-6-11;1-12(26)23-5-7-24(8-6-23)16-4-2-3-13(22-16)15-9-21-17-10-20-14(18(19)27)11-25(15)17;1-11(26)23-2-4-24(5-3-23)16-8-19-6-12(22-16)14-7-21-15-9-20-13(17(18)27)10-25(14)15;1-11(26)23-4-6-24(7-5-23)17-19-3-2-12(22-17)14-8-21-15-9-20-13(16(18)27)10-25(14)15;17-15(18)11-9-26-12(6-22-14(26)7-21-11)16-20-4-3-13(23-16)25-5-1-2-10(8-25)24-29(19,27)28/h1-2,5-8,10,14H,3-4,9H2,(H,25,26);2-4,9-11H,5-8H2,1H3,(H2,19,27);6-10H,2-5H2,1H3,(H2,18,27);2-3,8-10H,4-7H2,1H3,(H2,18,27);3-4,6-7,9-10,15,24H,1-2,5,8H2,(H2,19,27,28)/t;;;;10-/m....1/s1.

What are the key properties of 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine?

3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine has a molecular weight of 1938.97 g/mol, XLogP of 3.86, 17 rotatable bonds, 6 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for 3-[6-(4-acetylpiperazin-1-yl)pyrazin-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[6-(4-acetylpiperazin-1-yl)-2-pyridinyl]imidazo[1,2-a]pyrazine-6-carboxamide;3-[2-(4-acetylpiperazin-1-yl)pyrimidin-4-yl]imidazo[1,2-a]pyrazine-6-carboxamide;6-(difluoromethyl)-3-[4-[(3R)-3-(sulfamoylamino)piperidin-1-yl]pyrimidin-2-yl]imidazo[1,2-a]pyrazine;2-(1H-pyrazol-4-yl)-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]morpholine is sourced from PubChem (CID 160997820), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).