2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one

C107H103F18N39O6 — CID 161001473

About 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one

2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one (PubChem CID 161001473) has the molecular formula C107H103F18N39O6 and a molecular weight of 2373.23 g/mol. Its IUPAC name is 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one.

Molecular Properties

• Compound Name: 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one
• PubChem CID: 161001473
• Molecular Formula: C107H103F18N39O6
• Molecular Weight: 2373.23 g/mol
• Exact Mass: 2371.87
• IUPAC Name: 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one
• SMILES: CC(=O)CC1CCCN(c2ccnc(-c3cnc4cnc(C(F)(F)F)cn34)n2)C1.CC1(C)CN(c2ccnc(-c3cnc4cnc(C(F)(F)F)cn34)n2)CCO1.CC1(C)COCCN1c1ccnc(-c2cnc3cnc(C(F)(F)F)cn23)n1.NC(=O)CC1CCCN(c2ccnc(-c3cnc4cnc(C(F)(F)F)cn34)n2)C1.O=C1CC2(CCN(c3ccnc(-c4cnc5cnc(C(F)(F)F)cn45)n3)C2)CN1.O=C1NCCC12CCN(c1ccnc(-c3cnc4cnc(C(F)(F)F)cn34)n1)C2
• InChI: InChI=1S/C19H19F3N6O.2C18H16F3N7O.C18H18F3N7O.2C17H17F3N6O/c1-12(29)7-13-3-2-6-27(10-13)16-4-5-23-18(26-16)14-8-25-17-9-24-15(11-28(14)17)19(20,21)22;19-18(20,21)12-9-28-11(7-25-14(28)8-24-12)15-22-4-1-13(26-15)27-6-3-17(10-27)2-5-23-16(17)29;19-18(20,21)12-8-28-11(6-24-14(28)7-23-12)16-22-3-1-13(26-16)27-4-2-17(10-27)5-15(29)25-9-17;19-18(20,21)13-10-28-12(7-25-16(28)8-24-13)17-23-4-3-15(26-17)27-5-1-2-11(9-27)6-14(22)29;1-16(2)10-27-6-5-26(16)13-3-4-21-15(24-13)11-7-23-14-8-22-12(9-25(11)14)17(18,19)20;1-16(2)10-25(5-6-27-16)13-3-4-21-15(24-13)11-7-23-14-8-22-12(9-26(11)14)17(18,19)20/h4-5,8-9,11,13H,2-3,6-7,10H2,1H3;1,4,7-9H,2-3,5-6,10H2,(H,23,29);1,3,6-8H,2,4-5,9-10H2,(H,25,29);3-4,7-8,10-11H,1-2,5-6,9H2,(H2,22,29);2*3-4,7-9H,5-6,10H2,1-2H3
• InChIKey: TVXXVGFVHSOUEK-UHFFFAOYSA-N
• XLogP: 15.18
• TPSA: 492.08 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 42
• Rotatable Bonds: 16
• Heavy Atoms: 170
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2373.23
LogP ≤ 5	15.18
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	42

Frequently Asked Questions

What is the IUPAC name of 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one?

The IUPAC name of 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one (CID 161001473) is 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one.

What is the SMILES notation for 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one?

The canonical SMILES for 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one is CC(=O)CC1CCCN(c2ccnc(-c3cnc4cnc(C(F)(F)F)cn34)n2)C1.CC1(C)CN(c2ccnc(-c3cnc4cnc(C(F)(F)F)cn34)n2)CCO1.CC1(C)COCCN1c1ccnc(-c2cnc3cnc(C(F)(F)F)cn23)n1.NC(=O)CC1CCCN(c2ccnc(-c3cnc4cnc(C(F)(F)F)cn34)n2)C1.O=C1CC2(CCN(c3ccnc(-c4cnc5cnc(C(F)(F)F)cn45)n3)C2)CN1.O=C1NCCC12CCN(c1ccnc(-c3cnc4cnc(C(F)(F)F)cn34)n1)C2.

What is the InChIKey of 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one?

The InChIKey is TVXXVGFVHSOUEK-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H19F3N6O.2C18H16F3N7O.C18H18F3N7O.2C17H17F3N6O/c1-12(29)7-13-3-2-6-27(10-13)16-4-5-23-18(26-16)14-8-25-17-9-24-15(11-28(14)17)19(20,21)22;19-18(20,21)12-9-28-11(7-25-14(28)8-24-12)15-22-4-1-13(26-15)27-6-3-17(10-27)2-5-23-16(17)29;19-18(20,21)12-8-28-11(6-24-14(28)7-23-12)16-22-3-1-13(26-16)27-4-2-17(10-27)5-15(29)25-9-17;19-18(20,21)13-10-28-12(7-25-16(28)8-24-13)17-23-4-3-15(26-17)27-5-1-2-11(9-27)6-14(22)29;1-16(2)10-27-6-5-26(16)13-3-4-21-15(24-13)11-7-23-14-8-22-12(9-25(11)14)17(18,19)20;1-16(2)10-25(5-6-27-16)13-3-4-21-15(24-13)11-7-23-14-8-22-12(9-26(11)14)17(18,19)20/h4-5,8-9,11,13H,2-3,6-7,10H2,1H3;1,4,7-9H,2-3,5-6,10H2,(H,23,29);1,3,6-8H,2,4-5,9-10H2,(H,25,29);3-4,7-8,10-11H,1-2,5-6,9H2,(H2,22,29);2*3-4,7-9H,5-6,10H2,1-2H3.

What are the key properties of 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one?

2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one has a molecular weight of 2373.23 g/mol, XLogP of 15.18, 16 rotatable bonds, 3 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for 2,2-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;3,3-dimethyl-4-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]morpholine;2-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-8-one;7-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]-2,7-diazaspiro[4.4]nonan-1-one;2-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide;1-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-4-yl]piperidin-3-yl]propan-2-one is sourced from PubChem (CID 161001473), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).