(Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one

C131H131F4N25O12 — CID 161005299

IUPAC(Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one
SMILESCCOc1cc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C/[C@@H]1CCCN1C.CCOc1cc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C\[C@@H]1CCCN1C.CCOc1cc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C\[C@H]1CCCN1C.CCOc1cc2ncnc(Nc3ccc(Oc4ccn5cnnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C/[C@H]1CCCN1C
InChIInChI=1S/3C33H33FN6O3.C32H32FN7O3/c3*1-4-42-31-19-28-26(15-22(31)16-29(41)27(34)17-24-6-5-11-39(24)3)33(37-20-36-28)38-23-7-8-30(21(2)14-23)43-25-9-12-40-13-10-35-32(40)18-25;1-4-42-30-17-27-25(13-21(30)14-28(41)26(33)15-23-6-5-10-39(23)3)32(35-18-34-27)37-22-7-8-29(20(2)12-22)43-24-9-11-40-19-36-38-31(40)16-24/h3*7-10,12-15,17-20,24H,4-6,11,16H2,1-3H3,(H,36,37,38);7-9,11-13,15-19,23H,4-6,10,14H2,1-3H3,(H,34,35,37)/b2*27-17+;27-17-;26-15-/t3*24-;23-/m1001/s1
InChIKeyTWKPWQSVTGZYST-GWSCFDDHSA-N
MW2323.64 g/mol
LogP25.71
Rot. Bonds40

About (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one

(Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one (PubChem CID 161005299) has the molecular formula C131H131F4N25O12 and a molecular weight of 2323.64 g/mol. Its IUPAC name is (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one.

Molecular Properties

Compound Name(Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one
PubChem CID161005299
Molecular FormulaC131H131F4N25O12
Molecular Weight2323.64 g/mol
Exact Mass2322.03
IUPAC Name(Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one
SMILESCCOc1cc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C/[C@@H]1CCCN1C.CCOc1cc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C\[C@@H]1CCCN1C.CCOc1cc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C\[C@H]1CCCN1C.CCOc1cc2ncnc(Nc3ccc(Oc4ccn5cnnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C/[C@H]1CCCN1C
InChIInChI=1S/3C33H33FN6O3.C32H32FN7O3/c3*1-4-42-31-19-28-26(15-22(31)16-29(41)27(34)17-24-6-5-11-39(24)3)33(37-20-36-28)38-23-7-8-30(21(2)14-23)43-25-9-12-40-13-10-35-32(40)18-25;1-4-42-30-17-27-25(13-21(30)14-28(41)26(33)15-23-6-5-10-39(23)3)32(35-18-34-27)37-22-7-8-29(20(2)12-22)43-24-9-11-40-19-36-38-31(40)16-24/h3*7-10,12-15,17-20,24H,4-6,11,16H2,1-3H3,(H,36,37,38);7-9,11-13,15-19,23H,4-6,10,14H2,1-3H3,(H,34,35,37)/b2*27-17+;27-17-;26-15-/t3*24-;23-/m1001/s1
InChIKeyTWKPWQSVTGZYST-GWSCFDDHSA-N
XLogP25.71
TPSA388.41 Ų
H-Bond Donors4
H-Bond Acceptors37
Rotatable Bonds40
Heavy Atoms172
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002323.64
LogP ≤ 525.71
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1037

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'ene_one_hal(17)', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}

Analyze (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one with MolForge

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Launch Full Analysis

Related Compounds

(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-4-[(2R)-pyrrolidin-2-yl]but-3-en-2-one
CID 158591061
(Z)-2-fluoro-N-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-2-methoxy-5-methylanilino)-7-methoxyquinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
CID 169230803
(E)-2-fluoro-N-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-2-methoxy-5-methylanilino)-7-methoxyquinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
CID 169230633
N-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-2-propylpentanamide
CID 71196517
N-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]prop-2-enamide
CID 88975129
1-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-methoxypropan-2-one
CID 58140197
N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-[2-(1-methylpiperidin-4-yl)ethoxy]quinazolin-4-amine
CID 58139948
N-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]but-2-ynamide
CID 162431474
N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-[2-(4-methylpiperazin-1-yl)ethoxy]quinazolin-4-amine
CID 58140046
(E)-2-fluoro-N-[7-methoxy-4-[2-methoxy-5-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-[(2S)-1-methylpyrrolidin-2-yl]prop-2-enamide
CID 169230625
(E)-2-fluoro-N-[7-methoxy-4-[2-methoxy-5-methyl-4-[(1-methyl-2-oxo-4-pyridinyl)oxy]anilino]quinazolin-6-yl]-3-(1-methylpyrrolidin-2-yl)prop-2-enamide
CID 170169210
N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine
CID 58139984

Frequently Asked Questions

What is the IUPAC name of (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one?
The IUPAC name of (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one (CID 161005299) is (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one.
What is the SMILES notation for (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one?
The canonical SMILES for (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one is CCOc1cc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C/[C@@H]1CCCN1C.CCOc1cc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C\[C@@H]1CCCN1C.CCOc1cc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C\[C@H]1CCCN1C.CCOc1cc2ncnc(Nc3ccc(Oc4ccn5cnnc5c4)c(C)c3)c2cc1CC(=O)/C(F)=C/[C@H]1CCCN1C.
What is the InChIKey of (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one?
The InChIKey is TWKPWQSVTGZYST-GWSCFDDHSA-N. The full InChI is InChI=1S/3C33H33FN6O3.C32H32FN7O3/c3*1-4-42-31-19-28-26(15-22(31)16-29(41)27(34)17-24-6-5-11-39(24)3)33(37-20-36-28)38-23-7-8-30(21(2)14-23)43-25-9-12-40-13-10-35-32(40)18-25;1-4-42-30-17-27-25(13-21(30)14-28(41)26(33)15-23-6-5-10-39(23)3)32(35-18-34-27)37-22-7-8-29(20(2)12-22)43-24-9-11-40-19-36-38-31(40)16-24/h3*7-10,12-15,17-20,24H,4-6,11,16H2,1-3H3,(H,36,37,38);7-9,11-13,15-19,23H,4-6,10,14H2,1-3H3,(H,34,35,37)/b2*27-17+;27-17-;26-15-/t3*24-;23-/m1001/s1.
What are the key properties of (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one?
(Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one has a molecular weight of 2323.64 g/mol, XLogP of 25.71, 40 rotatable bonds, 4 hydrogen bond donors, and 37 hydrogen bond acceptors.
Where does this data come from?
All data for (Z)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2S)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(E)-1-[7-ethoxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one;(Z)-1-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-fluoro-4-[(2R)-1-methylpyrrolidin-2-yl]but-3-en-2-one is sourced from PubChem (CID 161005299), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).