6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane

C83H67F8N15O6 — CID 161010019

About 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane

6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane (PubChem CID 161010019) has the molecular formula C83H67F8N15O6 and a molecular weight of 1522.53 g/mol. Its IUPAC name is 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane.

Molecular Properties

• Compound Name: 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane
• PubChem CID: 161010019
• Molecular Formula: C83H67F8N15O6
• Molecular Weight: 1522.53 g/mol
• Exact Mass: 1521.53
• IUPAC Name: 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane
• SMILES: C.CC1(C)C(=O)N(c2ncccn2)c2cccc(-c3ccc(C(F)(F)F)c(C(=O)Nc4ccc(F)cc4)n3)c21.Cc1ccc(-c2cccc3c2C(C)(C)C(=O)N3c2ncccn2)nc1C(=O)Nc1ccc(F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccc4c3C(C)(C)C(=O)N4c3ncccn3)ncc2C(F)(F)F)cc1
• InChI: InChI=1S/C28H22F3N5O2.C27H19F4N5O2.C27H22FN5O2.CH4/c1-16-8-10-17(11-9-16)35-24(37)19-14-21(34-15-20(19)28(29,30)31)18-6-4-7-22-23(18)27(2,3)25(38)36(22)26-32-12-5-13-33-26;1-26(2)21-17(5-3-6-20(21)36(24(26)38)25-32-13-4-14-33-25)19-12-11-18(27(29,30)31)22(35-19)23(37)34-16-9-7-15(28)8-10-16;1-16-8-13-20(32-23(16)24(34)31-18-11-9-17(28)10-12-18)19-6-4-7-21-22(19)27(2,3)25(35)33(21)26-29-14-5-15-30-26;/h4-15H,1-3H3,(H,35,37);3-14H,1-2H3,(H,34,37);4-15H,1-3H3,(H,31,34);1H4
• InChIKey: TWZYYHJTFXYSGJ-UHFFFAOYSA-N
• XLogP: 17.81
• TPSA: 264.24 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 15
• Rotatable Bonds: 12
• Heavy Atoms: 112
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1522.53
LogP ≤ 5	17.81
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	15

Frequently Asked Questions

What is the IUPAC name of 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane?

The IUPAC name of 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane (CID 161010019) is 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane.

What is the SMILES notation for 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane?

The canonical SMILES for 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane is C.CC1(C)C(=O)N(c2ncccn2)c2cccc(-c3ccc(C(F)(F)F)c(C(=O)Nc4ccc(F)cc4)n3)c21.Cc1ccc(-c2cccc3c2C(C)(C)C(=O)N3c2ncccn2)nc1C(=O)Nc1ccc(F)cc1.Cc1ccc(NC(=O)c2cc(-c3cccc4c3C(C)(C)C(=O)N4c3ncccn3)ncc2C(F)(F)F)cc1.

What is the InChIKey of 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane?

The InChIKey is TWZYYHJTFXYSGJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H22F3N5O2.C27H19F4N5O2.C27H22FN5O2.CH4/c1-16-8-10-17(11-9-16)35-24(37)19-14-21(34-15-20(19)28(29,30)31)18-6-4-7-22-23(18)27(2,3)25(38)36(22)26-32-12-5-13-33-26;1-26(2)21-17(5-3-6-20(21)36(24(26)38)25-32-13-4-14-33-25)19-12-11-18(27(29,30)31)22(35-19)23(37)34-16-9-7-15(28)8-10-16;1-16-8-13-20(32-23(16)24(34)31-18-11-9-17(28)10-12-18)19-6-4-7-21-22(19)27(2,3)25(35)33(21)26-29-14-5-15-30-26;/h4-15H,1-3H3,(H,35,37);3-14H,1-2H3,(H,34,37);4-15H,1-3H3,(H,31,34);1H4.

What are the key properties of 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane?

6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane has a molecular weight of 1522.53 g/mol, XLogP of 17.81, 12 rotatable bonds, 3 hydrogen bond donors, and 15 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-methylpyridine-2-carboxamide;6-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-fluorophenyl)-3-(trifluoromethyl)pyridine-2-carboxamide;2-(3,3-dimethyl-2-oxo-1-pyrimidin-2-ylindol-4-yl)-N-(4-methylphenyl)-5-(trifluoromethyl)pyridine-4-carboxamide;methane is sourced from PubChem (CID 161010019), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).