N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide

C111H91F8N23O5S5 — CID 161017810

About N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide

N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide (PubChem CID 161017810) has the molecular formula C111H91F8N23O5S5 and a molecular weight of 2139.42 g/mol. Its IUPAC name is N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide.

Molecular Properties

• Compound Name: N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide
• PubChem CID: 161017810
• Molecular Formula: C111H91F8N23O5S5
• Molecular Weight: 2139.42 g/mol
• Exact Mass: 2137.60
• IUPAC Name: N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide
• SMILES: CC(C)c1sc(-c2cnn(C)c2)nc1-c1ccc(NC(=O)c2ccc(F)cc2F)nc1.CCc1sc(-c2ccc(N)nc2)nc1-c1ccc(NC(=O)c2cccc(F)c2C)nc1.CCc1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2cccc(F)c2C)nc1.Cc1sc(-c2cnn(C)c2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cc1sc(CCc2cccnc2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1
• InChI: InChI=1S/C23H18F2N4OS.C23H20FN5OS.C23H19FN4OS.C22H19F2N5OS.C20H15F2N5OS/c1-14-22(29-20(31-14)10-7-15-4-3-11-26-12-15)16-8-9-19(27-13-16)28-23(30)21-17(24)5-2-6-18(21)25;1-3-18-21(29-23(31-18)15-7-9-19(25)26-12-15)14-8-10-20(27-11-14)28-22(30)16-5-4-6-17(24)13(16)2;1-3-19-21(28-23(30-19)16-6-5-11-25-12-16)15-9-10-20(26-13-15)27-22(29)17-7-4-8-18(24)14(17)2;1-12(2)20-19(28-22(31-20)14-10-26-29(3)11-14)13-4-7-18(25-9-13)27-21(30)16-6-5-15(23)8-17(16)24;1-11-18(26-20(29-11)13-9-24-27(2)10-13)12-6-7-16(23-8-12)25-19(28)17-14(21)4-3-5-15(17)22/h2-6,8-9,11-13H,7,10H2,1H3,(H,27,28,30);4-12H,3H2,1-2H3,(H2,25,26)(H,27,28,30);4-13H,3H2,1-2H3,(H,26,27,29);4-12H,1-3H3,(H,25,27,30);3-10H,1-2H3,(H,23,25,28)
• InChIKey: TXYNPTCMCHWFGY-UHFFFAOYSA-N
• XLogP: 25.57
• TPSA: 374.73 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 28
• Rotatable Bonds: 25
• Heavy Atoms: 152
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2139.42
LogP ≤ 5	25.57
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	28

Frequently Asked Questions

What is the IUPAC name of N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide?

The IUPAC name of N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide (CID 161017810) is N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide.

What is the SMILES notation for N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide?

The canonical SMILES for N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide is CC(C)c1sc(-c2cnn(C)c2)nc1-c1ccc(NC(=O)c2ccc(F)cc2F)nc1.CCc1sc(-c2ccc(N)nc2)nc1-c1ccc(NC(=O)c2cccc(F)c2C)nc1.CCc1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2cccc(F)c2C)nc1.Cc1sc(-c2cnn(C)c2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cc1sc(CCc2cccnc2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.

What is the InChIKey of N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide?

The InChIKey is TXYNPTCMCHWFGY-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H18F2N4OS.C23H20FN5OS.C23H19FN4OS.C22H19F2N5OS.C20H15F2N5OS/c1-14-22(29-20(31-14)10-7-15-4-3-11-26-12-15)16-8-9-19(27-13-16)28-23(30)21-17(24)5-2-6-18(21)25;1-3-18-21(29-23(31-18)15-7-9-19(25)26-12-15)14-8-10-20(27-11-14)28-22(30)16-5-4-6-17(24)13(16)2;1-3-19-21(28-23(30-19)16-6-5-11-25-12-16)15-9-10-20(26-13-15)27-22(29)17-7-4-8-18(24)14(17)2;1-12(2)20-19(28-22(31-20)14-10-26-29(3)11-14)13-4-7-18(25-9-13)27-21(30)16-6-5-15(23)8-17(16)24;1-11-18(26-20(29-11)13-9-24-27(2)10-13)12-6-7-16(23-8-12)25-19(28)17-14(21)4-3-5-15(17)22/h2-6,8-9,11-13H,7,10H2,1H3,(H,27,28,30);4-12H,3H2,1-2H3,(H2,25,26)(H,27,28,30);4-13H,3H2,1-2H3,(H,26,27,29);4-12H,1-3H3,(H,25,27,30);3-10H,1-2H3,(H,23,25,28).

What are the key properties of N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide?

N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide has a molecular weight of 2139.42 g/mol, XLogP of 25.57, 25 rotatable bonds, 6 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-3-fluoro-2-methylbenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,4-difluoro-N-[5-[2-(1-methylpyrazol-4-yl)-5-propan-2-yl-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[5-methyl-2-(2-pyridin-3-ylethyl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide;N-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-3-fluoro-2-methylbenzamide is sourced from PubChem (CID 161017810), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).