N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine

C119H91ClF28N18S — CID 161019285

IUPACN-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine
SMILESCc1cccc(C)c1Nc1c(-c2ccc(F)cc2F)nc2cccc(C(F)(F)F)n12.Cc1cccc(Cl)c1Nc1c(-c2ccc(F)cc2F)nc2cccc(C(F)(F)F)n12.Cc1csc2nc(-c3ccc(F)cc3F)c(NC3CCCC3)n12.Fc1ccc(-c2nc3cccc(C(F)(F)F)n3c2NC2CCCC2)c(F)c1.Fc1ccc(-c2nc3cccc(C(F)(F)F)n3c2NC2CCCCC2)c(F)c1.Fc1ccc(Nc2c(-c3ccc(F)cc3F)nc3cccc(C(F)(F)F)n23)cc1
InChIInChI=1S/C22H16F5N3.C21H13ClF5N3.C20H11F6N3.C20H18F5N3.C19H16F5N3.C17H17F2N3S/c1-12-5-3-6-13(2)19(12)29-21-20(15-10-9-14(23)11-16(15)24)28-18-8-4-7-17(30(18)21)22(25,26)27;1-11-4-2-5-14(22)18(11)29-20-19(13-9-8-12(23)10-15(13)24)28-17-7-3-6-16(30(17)20)21(25,26)27;21-11-4-7-13(8-5-11)27-19-18(14-9-6-12(22)10-15(14)23)28-17-3-1-2-16(29(17)19)20(24,25)26;21-12-9-10-14(15(22)11-12)18-19(26-13-5-2-1-3-6-13)28-16(20(23,24)25)7-4-8-17(28)27-18;20-11-8-9-13(14(21)10-11)17-18(25-12-4-1-2-5-12)27-15(19(22,23)24)6-3-7-16(27)26-17;1-10-9-23-17-21-15(13-7-6-11(18)8-14(13)19)16(22(10)17)20-12-4-2-3-5-12/h3-11,29H,1-2H3;2-10,29H,1H3;1-10,27H;4,7-11,13,26H,1-3,5-6H2;3,6-10,12,25H,1-2,4-5H2;6-9,12,20H,2-5H2,1H3
InChIKeyTYDMOLGPBQJLJP-UHFFFAOYSA-N
MW2372.63 g/mol
LogP36.54
Rot. Bonds18

About N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine

N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine (PubChem CID 161019285) has the molecular formula C119H91ClF28N18S and a molecular weight of 2372.63 g/mol. Its IUPAC name is N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine.

Molecular Properties

Compound NameN-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine
PubChem CID161019285
Molecular FormulaC119H91ClF28N18S
Molecular Weight2372.63 g/mol
Exact Mass2370.66
IUPAC NameN-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine
SMILESCc1cccc(C)c1Nc1c(-c2ccc(F)cc2F)nc2cccc(C(F)(F)F)n12.Cc1cccc(Cl)c1Nc1c(-c2ccc(F)cc2F)nc2cccc(C(F)(F)F)n12.Cc1csc2nc(-c3ccc(F)cc3F)c(NC3CCCC3)n12.Fc1ccc(-c2nc3cccc(C(F)(F)F)n3c2NC2CCCC2)c(F)c1.Fc1ccc(-c2nc3cccc(C(F)(F)F)n3c2NC2CCCCC2)c(F)c1.Fc1ccc(Nc2c(-c3ccc(F)cc3F)nc3cccc(C(F)(F)F)n23)cc1
InChIInChI=1S/C22H16F5N3.C21H13ClF5N3.C20H11F6N3.C20H18F5N3.C19H16F5N3.C17H17F2N3S/c1-12-5-3-6-13(2)19(12)29-21-20(15-10-9-14(23)11-16(15)24)28-18-8-4-7-17(30(18)21)22(25,26)27;1-11-4-2-5-14(22)18(11)29-20-19(13-9-8-12(23)10-15(13)24)28-17-7-3-6-16(30(17)20)21(25,26)27;21-11-4-7-13(8-5-11)27-19-18(14-9-6-12(22)10-15(14)23)28-17-3-1-2-16(29(17)19)20(24,25)26;21-12-9-10-14(15(22)11-12)18-19(26-13-5-2-1-3-6-13)28-16(20(23,24)25)7-4-8-17(28)27-18;20-11-8-9-13(14(21)10-11)17-18(25-12-4-1-2-5-12)27-15(19(22,23)24)6-3-7-16(27)26-17;1-10-9-23-17-21-15(13-7-6-11(18)8-14(13)19)16(22(10)17)20-12-4-2-3-5-12/h3-11,29H,1-2H3;2-10,29H,1H3;1-10,27H;4,7-11,13,26H,1-3,5-6H2;3,6-10,12,25H,1-2,4-5H2;6-9,12,20H,2-5H2,1H3
InChIKeyTYDMOLGPBQJLJP-UHFFFAOYSA-N
XLogP36.54
TPSA175.98 Ų
H-Bond Donors6
H-Bond Acceptors19
Rotatable Bonds18
Heavy Atoms167
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002372.63
LogP ≤ 536.54
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1019

Analyze N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine?
The IUPAC name of N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine (CID 161019285) is N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine.
What is the SMILES notation for N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine?
The canonical SMILES for N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine is Cc1cccc(C)c1Nc1c(-c2ccc(F)cc2F)nc2cccc(C(F)(F)F)n12.Cc1cccc(Cl)c1Nc1c(-c2ccc(F)cc2F)nc2cccc(C(F)(F)F)n12.Cc1csc2nc(-c3ccc(F)cc3F)c(NC3CCCC3)n12.Fc1ccc(-c2nc3cccc(C(F)(F)F)n3c2NC2CCCC2)c(F)c1.Fc1ccc(-c2nc3cccc(C(F)(F)F)n3c2NC2CCCCC2)c(F)c1.Fc1ccc(Nc2c(-c3ccc(F)cc3F)nc3cccc(C(F)(F)F)n23)cc1.
What is the InChIKey of N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine?
The InChIKey is TYDMOLGPBQJLJP-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H16F5N3.C21H13ClF5N3.C20H11F6N3.C20H18F5N3.C19H16F5N3.C17H17F2N3S/c1-12-5-3-6-13(2)19(12)29-21-20(15-10-9-14(23)11-16(15)24)28-18-8-4-7-17(30(18)21)22(25,26)27;1-11-4-2-5-14(22)18(11)29-20-19(13-9-8-12(23)10-15(13)24)28-17-7-3-6-16(30(17)20)21(25,26)27;21-11-4-7-13(8-5-11)27-19-18(14-9-6-12(22)10-15(14)23)28-17-3-1-2-16(29(17)19)20(24,25)26;21-12-9-10-14(15(22)11-12)18-19(26-13-5-2-1-3-6-13)28-16(20(23,24)25)7-4-8-17(28)27-18;20-11-8-9-13(14(21)10-11)17-18(25-12-4-1-2-5-12)27-15(19(22,23)24)6-3-7-16(27)26-17;1-10-9-23-17-21-15(13-7-6-11(18)8-14(13)19)16(22(10)17)20-12-4-2-3-5-12/h3-11,29H,1-2H3;2-10,29H,1H3;1-10,27H;4,7-11,13,26H,1-3,5-6H2;3,6-10,12,25H,1-2,4-5H2;6-9,12,20H,2-5H2,1H3.
What are the key properties of N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine?
N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine has a molecular weight of 2372.63 g/mol, XLogP of 36.54, 18 rotatable bonds, 6 hydrogen bond donors, and 19 hydrogen bond acceptors.
Where does this data come from?
All data for N-(2-chloro-6-methylphenyl)-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclohexyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;N-cyclopentyl-6-(2,4-difluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-2-(2,4-difluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(2,6-dimethylphenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine;2-(2,4-difluorophenyl)-N-(4-fluorophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridin-3-amine is sourced from PubChem (CID 161019285), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).