2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide

C148H146Cl8F18N40O18S6 — CID 161037166

About 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide

2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide (PubChem CID 161037166) has the molecular formula C148H146Cl8F18N40O18S6 and a molecular weight of 3591.05 g/mol. Its IUPAC name is 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide.

Molecular Properties

• Compound Name: 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide
• PubChem CID: 161037166
• Molecular Formula: C148H146Cl8F18N40O18S6
• Molecular Weight: 3591.05 g/mol
• Exact Mass: 3584.73
• IUPAC Name: 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide
• SMILES: CC(CC(=O)c1cc(-n2ccnc2)ncn1)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.CC(CC(=O)c1cc(CCCN2CCN(C(=O)OC(C)(C)C)CC2)ncn1)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.CC(CC(=O)c1ncnc(CCCO)c1Cl)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.CC(CC(=O)c1ncnc(N)c1Cl)c1ncc(C(=O)Nc2cc(C(=O)N(C)C)c(Cl)c(C(F)(F)F)c2)s1.CC(NC(=O)c1cc(C#CCN2CCN(C(=O)OC(C)(C)C)CC2)ncn1)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.CCN(CC)CCCNc1cc(C(=O)CC(C)c2ncc(C(=O)Nc3cc(C(F)(F)F)c(Cl)cn3)s2)ncn1
• InChI: InChI=1S/C30H35ClF3N7O4S.C29H30ClF3N8O4S.C25H29ClF3N7O2S.C22H19Cl2F3N6O3S.C21H18Cl2F3N5O3S.C21H15ClF3N7O2S/c1-18(27-36-16-24(46-27)26(43)39-25-14-20(30(32,33)34)21(31)15-35-25)12-23(42)22-13-19(37-17-38-22)6-5-7-40-8-10-41(11-9-40)28(44)45-29(2,3)4;1-17(26-35-15-22(46-26)25(43)39-23-13-19(29(31,32)33)20(30)14-34-23)38-24(42)21-12-18(36-16-37-21)6-5-7-40-8-10-41(11-9-40)27(44)45-28(2,3)4;1-4-36(5-2)8-6-7-30-21-11-18(33-14-34-21)19(37)9-15(3)24-32-13-20(39-24)23(38)35-22-10-16(25(27,28)29)17(26)12-31-22;1-9(4-13(34)17-16(24)18(28)31-8-30-17)20-29-7-14(37-20)19(35)32-10-5-11(21(36)33(2)3)15(23)12(6-10)22(25,26)27;1-10(5-14(33)18-17(23)13(3-2-4-32)29-9-30-18)20-28-8-15(35-20)19(34)31-16-6-11(21(24,25)26)12(22)7-27-16;1-11(4-15(33)14-6-18(30-9-29-14)32-3-2-26-10-32)20-28-8-16(35-20)19(34)31-17-5-12(21(23,24)25)13(22)7-27-17/h13-18H,5-12H2,1-4H3,(H,35,39,43);12-17H,7-11H2,1-4H3,(H,38,42)(H,34,39,43);10-15H,4-9H2,1-3H3,(H,30,33,34)(H,31,35,38);5-9H,4H2,1-3H3,(H,32,35)(H2,28,30,31);6-10,32H,2-5H2,1H3,(H,27,31,34);2-3,5-11H,4H2,1H3,(H,27,31,34)
• InChIKey: UAKBTBIQJOAOBY-UHFFFAOYSA-N
• XLogP: 31.73
• TPSA: 750.73 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 54
• Rotatable Bonds: 52
• Heavy Atoms: 238
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3591.05
LogP ≤ 5	31.73
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	54

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'triple_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide?

The IUPAC name of 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide (CID 161037166) is 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide.

What is the SMILES notation for 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide?

The canonical SMILES for 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide is CC(CC(=O)c1cc(-n2ccnc2)ncn1)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.CC(CC(=O)c1cc(CCCN2CCN(C(=O)OC(C)(C)C)CC2)ncn1)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.CC(CC(=O)c1ncnc(CCCO)c1Cl)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.CC(CC(=O)c1ncnc(N)c1Cl)c1ncc(C(=O)Nc2cc(C(=O)N(C)C)c(Cl)c(C(F)(F)F)c2)s1.CC(NC(=O)c1cc(C#CCN2CCN(C(=O)OC(C)(C)C)CC2)ncn1)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1.CCN(CC)CCCNc1cc(C(=O)CC(C)c2ncc(C(=O)Nc3cc(C(F)(F)F)c(Cl)cn3)s2)ncn1.

What is the InChIKey of 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide?

The InChIKey is UAKBTBIQJOAOBY-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H35ClF3N7O4S.C29H30ClF3N8O4S.C25H29ClF3N7O2S.C22H19Cl2F3N6O3S.C21H18Cl2F3N5O3S.C21H15ClF3N7O2S/c1-18(27-36-16-24(46-27)26(43)39-25-14-20(30(32,33)34)21(31)15-35-25)12-23(42)22-13-19(37-17-38-22)6-5-7-40-8-10-41(11-9-40)28(44)45-29(2,3)4;1-17(26-35-15-22(46-26)25(43)39-23-13-19(29(31,32)33)20(30)14-34-23)38-24(42)21-12-18(36-16-37-21)6-5-7-40-8-10-41(11-9-40)27(44)45-28(2,3)4;1-4-36(5-2)8-6-7-30-21-11-18(33-14-34-21)19(37)9-15(3)24-32-13-20(39-24)23(38)35-22-10-16(25(27,28)29)17(26)12-31-22;1-9(4-13(34)17-16(24)18(28)31-8-30-17)20-29-7-14(37-20)19(35)32-10-5-11(21(36)33(2)3)15(23)12(6-10)22(25,26)27;1-10(5-14(33)18-17(23)13(3-2-4-32)29-9-30-18)20-28-8-15(35-20)19(34)31-16-6-11(21(24,25)26)12(22)7-27-16;1-11(4-15(33)14-6-18(30-9-29-14)32-3-2-26-10-32)20-28-8-16(35-20)19(34)31-17-5-12(21(23,24)25)13(22)7-27-17/h13-18H,5-12H2,1-4H3,(H,35,39,43);12-17H,7-11H2,1-4H3,(H,38,42)(H,34,39,43);10-15H,4-9H2,1-3H3,(H,30,33,34)(H,31,35,38);5-9H,4H2,1-3H3,(H,32,35)(H2,28,30,31);6-10,32H,2-5H2,1H3,(H,27,31,34);2-3,5-11H,4H2,1H3,(H,27,31,34).

What are the key properties of 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide?

2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide has a molecular weight of 3591.05 g/mol, XLogP of 31.73, 52 rotatable bonds, 10 hydrogen bond donors, and 54 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[4-(6-amino-5-chloropyrimidin-4-yl)-4-oxobutan-2-yl]-N-[4-chloro-3-(dimethylcarbamoyl)-5-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide;tert-butyl 4-[3-[6-[3-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]butanoyl]pyrimidin-4-yl]propyl]piperazine-1-carboxylate;tert-butyl 4-[3-[6-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethylcarbamoyl]pyrimidin-4-yl]prop-2-ynyl]piperazine-1-carboxylate;2-[4-[5-chloro-6-(3-hydroxypropyl)pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(diethylamino)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-(6-imidazol-1-ylpyrimidin-4-yl)-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide is sourced from PubChem (CID 161037166), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).