3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile

C92H54Cl6F4N30O — CID 161058779

IUPAC3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile
SMILESCOc1cccc(-c2nc(N)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)c1.Cc1cccc(-c2nc(N)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)c1.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccc(F)c(F)c2)nc1N.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccc(F)cc2F)nc1N.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2cccc(Cl)c2)nc1N
InChIInChI=1S/C19H13ClN6O.C19H13ClN6.C18H10Cl2N6.2C18H9ClF2N6/c1-27-13-4-2-3-10(6-13)17-18(24-15(8-21)19(22)25-17)11-5-12-9-23-26-16(12)14(20)7-11;1-10-3-2-4-11(5-10)17-18(24-15(8-21)19(22)25-17)12-6-13-9-23-26-16(13)14(20)7-12;19-12-3-1-2-9(5-12)16-17(24-14(7-21)18(22)25-16)10-4-11-8-23-26-15(11)13(20)6-10;19-12-4-8(3-9-7-24-27-15(9)12)16-17(26-18(23)14(6-22)25-16)11-2-1-10(20)5-13(11)21;19-11-4-9(3-10-7-24-27-15(10)11)17-16(26-18(23)14(6-22)25-17)8-1-2-12(20)13(21)5-8/h2-7,9H,1H3,(H2,22,25)(H,23,26);2-7,9H,1H3,(H2,22,25)(H,23,26);1-6,8H,(H2,22,25)(H,23,26);2*1-5,7H,(H2,23,26)(H,24,27)
InChIKeyUDCPIGBCUKDXMZ-UHFFFAOYSA-N
MW1884.36 g/mol
LogP20.50
Rot. Bonds11

About 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile

3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile (PubChem CID 161058779) has the molecular formula C92H54Cl6F4N30O and a molecular weight of 1884.36 g/mol. Its IUPAC name is 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile.

Molecular Properties

Compound Name3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile
PubChem CID161058779
Molecular FormulaC92H54Cl6F4N30O
Molecular Weight1884.36 g/mol
Exact Mass1880.32
IUPAC Name3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile
SMILESCOc1cccc(-c2nc(N)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)c1.Cc1cccc(-c2nc(N)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)c1.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccc(F)c(F)c2)nc1N.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccc(F)cc2F)nc1N.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2cccc(Cl)c2)nc1N
InChIInChI=1S/C19H13ClN6O.C19H13ClN6.C18H10Cl2N6.2C18H9ClF2N6/c1-27-13-4-2-3-10(6-13)17-18(24-15(8-21)19(22)25-17)11-5-12-9-23-26-16(12)14(20)7-11;1-10-3-2-4-11(5-10)17-18(24-15(8-21)19(22)25-17)12-6-13-9-23-26-16(13)14(20)7-12;19-12-3-1-2-9(5-12)16-17(24-14(7-21)18(22)25-16)10-4-11-8-23-26-15(11)13(20)6-10;19-12-4-8(3-9-7-24-27-15(9)12)16-17(26-18(23)14(6-22)25-16)11-2-1-10(20)5-13(11)21;19-11-4-9(3-10-7-24-27-15(10)11)17-16(26-18(23)14(6-22)25-17)8-1-2-12(20)13(21)5-8/h2-7,9H,1H3,(H2,22,25)(H,23,26);2-7,9H,1H3,(H2,22,25)(H,23,26);1-6,8H,(H2,22,25)(H,23,26);2*1-5,7H,(H2,23,26)(H,24,27)
InChIKeyUDCPIGBCUKDXMZ-UHFFFAOYSA-N
XLogP20.50
TPSA530.58 Ų
H-Bond Donors10
H-Bond Acceptors26
Rotatable Bonds11
Heavy Atoms133
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001884.36
LogP ≤ 520.50
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1026

Analyze 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile with MolForge

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Related Compounds

4-[[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]oxymethyl]benzonitrile;5-(7-chloro-1H-indazol-5-yl)-3-[(4-fluorophenyl)methoxy]-6-phenylpyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-3-[(1-methylpiperidin-4-yl)methoxy]-6-phenylpyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenyl-3-(pyridin-3-ylmethoxy)pyrazin-2-amine;5-(7-chloro-1H-indazol-5-yl)-6-phenyl-3-[2-[3-(trifluoromethyl)pyrrol-1-yl]ethoxy]pyrazin-2-amine
CID 158404941
2-chloro-3-[6-(4-ethyl-4-methylpiperidin-1-yl)-2H-pyrazolo[3,4-b]pyrazin-3-yl]benzonitrile;1-[3-(2-chlorophenyl)-2H-pyrazolo[3,4-b]pyrazin-6-yl]-4-ethynylpiperidin-4-amine;6-(4-ethyl-4-methylpiperidin-1-yl)-3-(2-fluoro-3-methylphenyl)-2H-pyrazolo[3,4-b]pyrazine;6-(4-ethyl-4-methylpiperidin-1-yl)-3-[2-fluoro-3-(trifluoromethoxy)phenyl]-2H-pyrazolo[3,4-b]pyrazine;6-(4-ethyl-4-methylpiperidin-1-yl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]-2H-pyrazolo[3,4-b]pyrazine
CID 158460713
1-butyl-5-[[4-[(2-chlorophenyl)methyl]piperazin-1-yl]methyl]-3-(1-methylpyrazol-3-yl)indole;1-butyl-5-[[4-[(2-chlorophenyl)methyl]piperazin-1-yl]methyl]-3-(1-methylpyrazol-4-yl)indole;1-butyl-5-[[4-[(2-chlorophenyl)methyl]piperazin-1-yl]methyl]-3-(1H-pyrazol-5-yl)indole;1-butyl-5-[[4-[(2-chlorophenyl)methyl]piperazin-1-yl]methyl]-3-(2H-pyrrol-4-yl)indole;1-butyl-5-[[4-[(2,3-dimethylimidazol-4-yl)methyl]piperazin-1-yl]methyl]-3-[4-(trifluoromethoxy)phenyl]indole
CID 159343248
2-chloro-3-[6-(4-ethyl-4-methylpiperidin-1-yl)-2H-pyrazolo[3,4-b]pyrazin-3-yl]benzonitrile;bis(6-(4-ethyl-4-methylpiperidin-1-yl)-3-(2-fluoro-3-methylphenyl)-2H-pyrazolo[3,4-b]pyrazine);bis(6-(4-ethyl-4-methylpiperidin-1-yl)-3-[2-fluoro-3-(trifluoromethoxy)phenyl]-2H-pyrazolo[3,4-b]pyrazine)
CID 160758577
3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile
CID 137430742
1-[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]-3-[(4-methoxyphenyl)methyl]urea;1-[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]-3-[(1-methylazetidin-3-yl)methyl]urea;1-[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]-3-[(1-methylpyrrolidin-3-yl)methyl]urea;1-[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]-3-(oxan-4-ylmethyl)urea
CID 159749323
1-[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]-3-[(6-methoxy-3-pyridinyl)methyl]urea;1-[3-amino-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazin-2-yl]-3-[(1-methylpyrrol-3-yl)methyl]urea;3-(tert-butylamino)-6-(7-chloro-1H-indazol-5-yl)-5-phenylpyrazine-2-carbonitrile;6-(7-chloro-1H-indazol-5-yl)-3-(ethylamino)-5-phenylpyrazine-2-carbonitrile;6-(7-chloro-1H-indazol-5-yl)-5-phenyl-3-(propan-2-ylamino)pyrazine-2-carbonitrile
CID 162059788

Frequently Asked Questions

What is the IUPAC name of 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile?
The IUPAC name of 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile (CID 161058779) is 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile.
What is the SMILES notation for 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile?
The canonical SMILES for 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile is COc1cccc(-c2nc(N)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)c1.Cc1cccc(-c2nc(N)c(C#N)nc2-c2cc(Cl)c3[nH]ncc3c2)c1.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccc(F)c(F)c2)nc1N.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2ccc(F)cc2F)nc1N.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2cccc(Cl)c2)nc1N.
What is the InChIKey of 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile?
The InChIKey is UDCPIGBCUKDXMZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H13ClN6O.C19H13ClN6.C18H10Cl2N6.2C18H9ClF2N6/c1-27-13-4-2-3-10(6-13)17-18(24-15(8-21)19(22)25-17)11-5-12-9-23-26-16(12)14(20)7-11;1-10-3-2-4-11(5-10)17-18(24-15(8-21)19(22)25-17)12-6-13-9-23-26-16(13)14(20)7-12;19-12-3-1-2-9(5-12)16-17(24-14(7-21)18(22)25-16)10-4-11-8-23-26-15(11)13(20)6-10;19-12-4-8(3-9-7-24-27-15(9)12)16-17(26-18(23)14(6-22)25-16)11-2-1-10(20)5-13(11)21;19-11-4-9(3-10-7-24-27-15(10)11)17-16(26-18(23)14(6-22)25-17)8-1-2-12(20)13(21)5-8/h2-7,9H,1H3,(H2,22,25)(H,23,26);2-7,9H,1H3,(H2,22,25)(H,23,26);1-6,8H,(H2,22,25)(H,23,26);2*1-5,7H,(H2,23,26)(H,24,27).
What are the key properties of 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile?
3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile has a molecular weight of 1884.36 g/mol, XLogP of 20.50, 11 rotatable bonds, 10 hydrogen bond donors, and 26 hydrogen bond acceptors.
Where does this data come from?
All data for 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-chlorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-difluorophenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methoxyphenyl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methylphenyl)pyrazine-2-carbonitrile is sourced from PubChem (CID 161058779), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).