N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile

C141H142F2N20O18S6 — CID 161077041

About N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile

N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile (PubChem CID 161077041) has the molecular formula C141H142F2N20O18S6 and a molecular weight of 2635.21 g/mol. Its IUPAC name is N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile.

Molecular Properties

• Compound Name: N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile
• PubChem CID: 161077041
• Molecular Formula: C141H142F2N20O18S6
• Molecular Weight: 2635.21 g/mol
• Exact Mass: 2632.91
• IUPAC Name: N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile
• SMILES: CCCOc1ccc2c(C#N)c(-c3ccc(N4CCCS4(=O)=O)cc3)n(CC)c2c1.CCCS(=O)(=O)Nc1ccccc1-c1c(C#N)c2ccc(OC)cc2n1CC.CCn1c(-c2ccc(N3CCCS3(=O)=O)cc2)c(C#N)c2ccc(OC(C)C)cc21.CCn1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)c(C#N)c2ccc(OCc3cccnc3)cc21.CCn1c(-c2ccc(NS(=O)(=O)CC)cc2)c(C#N)c2ccc(OCc3cccnc3)cc21.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)n(CC2CC2)c2cc(OC(F)F)ccc12
• InChI: InChI=1S/C26H24N4O3S.C25H24N4O3S.C23H21F2N3O3S.2C23H25N3O3S.C21H23N3O3S/c1-2-30-25-14-21(33-17-18-4-3-13-28-16-18)9-12-23(25)24(15-27)26(30)19-5-7-20(8-6-19)29-34(31,32)22-10-11-22;1-3-29-24-14-21(32-17-18-6-5-13-27-16-18)11-12-22(24)23(15-26)25(29)19-7-9-20(10-8-19)28-33(30,31)4-2;24-23(25)31-17-7-10-19-20(12-26)22(28(21(19)11-17)13-14-1-2-14)15-3-5-16(6-4-15)27-32(29,30)18-8-9-18;1-4-25-22-14-19(29-16(2)3)10-11-20(22)21(15-24)23(25)17-6-8-18(9-7-17)26-12-5-13-30(26,27)28;1-3-13-29-19-10-11-20-21(16-24)23(25(4-2)22(20)15-19)17-6-8-18(9-7-17)26-12-5-14-30(26,27)28;1-4-12-28(25,26)23-19-9-7-6-8-17(19)21-18(14-22)16-11-10-15(27-3)13-20(16)24(21)5-2/h3-9,12-14,16,22,29H,2,10-11,17H2,1H3;5-14,16,28H,3-4,17H2,1-2H3;3-7,10-11,14,18,23,27H,1-2,8-9,13H2;6-11,14,16H,4-5,12-13H2,1-3H3;6-11,15H,3-5,12-14H2,1-2H3;6-11,13,23H,4-5,12H2,1-3H3
• InChIKey: UFKKFXMTKTYPSM-UHFFFAOYSA-N
• XLogP: 28.52
• TPSA: 512.92 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 32
• Rotatable Bonds: 42
• Heavy Atoms: 187
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2635.21
LogP ≤ 5	28.52
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile?

The IUPAC name of N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile (CID 161077041) is N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile.

What is the SMILES notation for N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile?

The canonical SMILES for N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile is CCCOc1ccc2c(C#N)c(-c3ccc(N4CCCS4(=O)=O)cc3)n(CC)c2c1.CCCS(=O)(=O)Nc1ccccc1-c1c(C#N)c2ccc(OC)cc2n1CC.CCn1c(-c2ccc(N3CCCS3(=O)=O)cc2)c(C#N)c2ccc(OC(C)C)cc21.CCn1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)c(C#N)c2ccc(OCc3cccnc3)cc21.CCn1c(-c2ccc(NS(=O)(=O)CC)cc2)c(C#N)c2ccc(OCc3cccnc3)cc21.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)n(CC2CC2)c2cc(OC(F)F)ccc12.

What is the InChIKey of N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile?

The InChIKey is UFKKFXMTKTYPSM-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H24N4O3S.C25H24N4O3S.C23H21F2N3O3S.2C23H25N3O3S.C21H23N3O3S/c1-2-30-25-14-21(33-17-18-4-3-13-28-16-18)9-12-23(25)24(15-27)26(30)19-5-7-20(8-6-19)29-34(31,32)22-10-11-22;1-3-29-24-14-21(32-17-18-6-5-13-27-16-18)11-12-22(24)23(15-26)25(29)19-7-9-20(10-8-19)28-33(30,31)4-2;24-23(25)31-17-7-10-19-20(12-26)22(28(21(19)11-17)13-14-1-2-14)15-3-5-16(6-4-15)27-32(29,30)18-8-9-18;1-4-25-22-14-19(29-16(2)3)10-11-20(22)21(15-24)23(25)17-6-8-18(9-7-17)26-12-5-13-30(26,27)28;1-3-13-29-19-10-11-20-21(16-24)23(25(4-2)22(20)15-19)17-6-8-18(9-7-17)26-12-5-14-30(26,27)28;1-4-12-28(25,26)23-19-9-7-6-8-17(19)21-18(14-22)16-11-10-15(27-3)13-20(16)24(21)5-2/h3-9,12-14,16,22,29H,2,10-11,17H2,1H3;5-14,16,28H,3-4,17H2,1-2H3;3-7,10-11,14,18,23,27H,1-2,8-9,13H2;6-11,14,16H,4-5,12-13H2,1-3H3;6-11,15H,3-5,12-14H2,1-2H3;6-11,13,23H,4-5,12H2,1-3H3.

What are the key properties of N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile?

N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile has a molecular weight of 2635.21 g/mol, XLogP of 28.52, 42 rotatable bonds, 4 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[2-(3-cyano-1-ethyl-6-methoxyindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-ethyl-6-(pyridin-3-ylmethoxy)indol-2-yl]phenyl]ethanesulfonamide;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propan-2-yloxyindole-3-carbonitrile;2-[4-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-1-ethyl-6-propoxyindole-3-carbonitrile is sourced from PubChem (CID 161077041), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).