6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one

C193H207Cl4F7N42O18S7 — CID 161092589

About 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one

6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one (PubChem CID 161092589) has the molecular formula C193H207Cl4F7N42O18S7 and a molecular weight of 3902.32 g/mol. Its IUPAC name is 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one.

Molecular Properties

• Compound Name: 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one
• PubChem CID: 161092589
• Molecular Formula: C193H207Cl4F7N42O18S7
• Molecular Weight: 3902.32 g/mol
• Exact Mass: 3897.33
• IUPAC Name: 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one
• SMILES: C=S(C)(=O)c1cccc(-c2cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4)nc3n(CC)c2=O)c1C(F)(F)F.C=S(C)(=O)c1cccc(-c2cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4)nc3n(CC)c2=O)c1Cl.CCn1c(=O)c(-c2cc(S(C)(=O)=O)ccc2C)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.CCn1c(=O)c(-c2cc(S(C)(=O)=O)ccc2Cl)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.CCn1c(=O)c(-c2ccc(S(C)(=O)=O)cc2Cl)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.CCn1c(=O)c(-c2ccc(S(C)(=O)=O)cc2Cl)cc2cnc(Nc3ccc(N4CCNCC4)c(F)c3)nc21.CCn1c(=O)c(-c2cccc(S(C)=O)c2C(F)(F)F)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21
• InChI: InChI=1S/C29H31F3N6O2S.C28H31ClN6O2S.C28H29F3N6O2S.C28H32N6O3S.2C27H29ClN6O3S.C26H26ClFN6O3S/c1-5-38-26-19(17-23(27(38)39)22-7-6-8-24(41(3,4)40)25(22)29(30,31)32)18-33-28(35-26)34-20-9-11-21(12-10-20)37-15-13-36(2)14-16-37;1-5-35-26-19(17-23(27(35)36)22-7-6-8-24(25(22)29)38(3,4)37)18-30-28(32-26)31-20-9-11-21(12-10-20)34-15-13-33(2)14-16-34;1-4-37-25-18(16-22(26(37)38)21-6-5-7-23(40(3)39)24(21)28(29,30)31)17-32-27(34-25)33-19-8-10-20(11-9-19)36-14-12-35(2)13-15-36;1-5-34-26-20(16-25(27(34)35)24-17-23(38(4,36)37)11-6-19(24)2)18-29-28(31-26)30-21-7-9-22(10-8-21)33-14-12-32(3)13-15-33;1-4-34-25-18(15-23(26(34)35)22-16-21(38(3,36)37)9-10-24(22)28)17-29-27(31-25)30-19-5-7-20(8-6-19)33-13-11-32(2)12-14-33;1-4-34-25-18(15-23(26(34)35)22-10-9-21(16-24(22)28)38(3,36)37)17-29-27(31-25)30-19-5-7-20(8-6-19)33-13-11-32(2)12-14-33;1-3-34-24-16(12-20(25(34)35)19-6-5-18(14-21(19)27)38(2,36)37)15-30-26(32-24)31-17-4-7-23(22(28)13-17)33-10-8-29-9-11-33/h6-12,17-18H,3,5,13-16H2,1-2,4H3,(H,33,34,35);6-12,17-18H,3,5,13-16H2,1-2,4H3,(H,30,31,32);5-11,16-17H,4,12-15H2,1-3H3,(H,32,33,34);6-11,16-18H,5,12-15H2,1-4H3,(H,29,30,31);2*5-10,15-17H,4,11-14H2,1-3H3,(H,29,30,31);4-7,12-15,29H,3,8-11H2,1-2H3,(H,30,31,32)
• InChIKey: UHJKXBUIERYZKF-UHFFFAOYSA-N
• XLogP: 29.33
• TPSA: 660.59 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 60
• Rotatable Bonds: 42
• Heavy Atoms: 271
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3902.32
LogP ≤ 5	29.33
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	60

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}, {'alert_name': 'Thiocarbonyl_group', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one?

The IUPAC name of 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one (CID 161092589) is 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one.

What is the SMILES notation for 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one?

The canonical SMILES for 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one is C=S(C)(=O)c1cccc(-c2cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4)nc3n(CC)c2=O)c1C(F)(F)F.C=S(C)(=O)c1cccc(-c2cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4)nc3n(CC)c2=O)c1Cl.CCn1c(=O)c(-c2cc(S(C)(=O)=O)ccc2C)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.CCn1c(=O)c(-c2cc(S(C)(=O)=O)ccc2Cl)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.CCn1c(=O)c(-c2ccc(S(C)(=O)=O)cc2Cl)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.CCn1c(=O)c(-c2ccc(S(C)(=O)=O)cc2Cl)cc2cnc(Nc3ccc(N4CCNCC4)c(F)c3)nc21.CCn1c(=O)c(-c2cccc(S(C)=O)c2C(F)(F)F)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21.

What is the InChIKey of 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one?

The InChIKey is UHJKXBUIERYZKF-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H31F3N6O2S.C28H31ClN6O2S.C28H29F3N6O2S.C28H32N6O3S.2C27H29ClN6O3S.C26H26ClFN6O3S/c1-5-38-26-19(17-23(27(38)39)22-7-6-8-24(41(3,4)40)25(22)29(30,31)32)18-33-28(35-26)34-20-9-11-21(12-10-20)37-15-13-36(2)14-16-37;1-5-35-26-19(17-23(27(35)36)22-7-6-8-24(25(22)29)38(3,4)37)18-30-28(32-26)31-20-9-11-21(12-10-20)34-15-13-33(2)14-16-34;1-4-37-25-18(16-22(26(37)38)21-6-5-7-23(40(3)39)24(21)28(29,30)31)17-32-27(34-25)33-19-8-10-20(11-9-19)36-14-12-35(2)13-15-36;1-5-34-26-20(16-25(27(34)35)24-17-23(38(4,36)37)11-6-19(24)2)18-29-28(31-26)30-21-7-9-22(10-8-21)33-14-12-32(3)13-15-33;1-4-34-25-18(15-23(26(34)35)22-16-21(38(3,36)37)9-10-24(22)28)17-29-27(31-25)30-19-5-7-20(8-6-19)33-13-11-32(2)12-14-33;1-4-34-25-18(15-23(26(34)35)22-10-9-21(16-24(22)28)38(3,36)37)17-29-27(31-25)30-19-5-7-20(8-6-19)33-13-11-32(2)12-14-33;1-3-34-24-16(12-20(25(34)35)19-6-5-18(14-21(19)27)38(2,36)37)15-30-26(32-24)31-17-4-7-23(22(28)13-17)33-10-8-29-9-11-33/h6-12,17-18H,3,5,13-16H2,1-2,4H3,(H,33,34,35);6-12,17-18H,3,5,13-16H2,1-2,4H3,(H,30,31,32);5-11,16-17H,4,12-15H2,1-3H3,(H,32,33,34);6-11,16-18H,5,12-15H2,1-4H3,(H,29,30,31);2*5-10,15-17H,4,11-14H2,1-3H3,(H,29,30,31);4-7,12-15,29H,3,8-11H2,1-2H3,(H,30,31,32).

What are the key properties of 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one?

6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one has a molecular weight of 3902.32 g/mol, XLogP of 29.33, 42 rotatable bonds, 8 hydrogen bond donors, and 60 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[2-chloro-3-(methyl-methylidene-oxo-λ6-sulfanyl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-4-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-chloro-5-methylsulfonylphenyl)-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-[3-(methyl-methylidene-oxo-λ6-sulfanyl)-2-(trifluoromethyl)phenyl]-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-6-(2-methyl-5-methylsulfonylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]-6-[3-methylsulfinyl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one is sourced from PubChem (CID 161092589), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).