About 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one
8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one (PubChem CID 161093169) has the molecular formula C21H21N7O
and a molecular weight of 387.45 g/mol. Its IUPAC name is 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one.
Molecular Properties
| Compound Name | 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one |
| PubChem CID | 161093169 |
| Molecular Formula | C21H21N7O |
| Molecular Weight | 387.45 g/mol |
| Exact Mass | 387.18 |
| IUPAC Name | 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one |
| SMILES | CNc1ncc(-c2cc(NC[C@@H](C)c3cccc4c3N=CCC4=O)ncn2)cn1 |
| InChI | InChI=1S/C21H21N7O/c1-13(15-4-3-5-16-18(29)6-7-23-20(15)16)9-24-19-8-17(27-12-28-19)14-10-25-21(22-2)26-11-14/h3-5,7-8,10-13H,6,9H2,1-2H3,(H,22,25,26)(H,24,27,28)/t13-/m1/s1 |
| InChIKey | HDJRUSAMEAFGLH-CYBMUJFWSA-N |
| XLogP | 3.48 |
| TPSA | 105.05 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 29 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 387.45 |
| LogP ≤ 5 | 3.48 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 8 |
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Frequently Asked Questions
What is the IUPAC name of 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one?
The IUPAC name of 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one (CID 161093169) is 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one.
What is the SMILES notation for 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one?
The canonical SMILES for 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one is CNc1ncc(-c2cc(NC[C@@H](C)c3cccc4c3N=CCC4=O)ncn2)cn1.
What is the InChIKey of 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one?
The InChIKey is HDJRUSAMEAFGLH-CYBMUJFWSA-N. The full InChI is InChI=1S/C21H21N7O/c1-13(15-4-3-5-16-18(29)6-7-23-20(15)16)9-24-19-8-17(27-12-28-19)14-10-25-21(22-2)26-11-14/h3-5,7-8,10-13H,6,9H2,1-2H3,(H,22,25,26)(H,24,27,28)/t13-/m1/s1.
What are the key properties of 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one?
8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one has a molecular weight of 387.45 g/mol, XLogP of 3.48, 6 rotatable bonds, 2 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 8-[(2S)-1-[[6-[2-(methylamino)pyrimidin-5-yl]pyrimidin-4-yl]amino]propan-2-yl]-3H-quinolin-4-one is sourced from PubChem (CID 161093169), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).