6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide

C126H110Cl2F6N14O18 — CID 161122587

About 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide

6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide (PubChem CID 161122587) has the molecular formula C126H110Cl2F6N14O18 and a molecular weight of 2293.24 g/mol. Its IUPAC name is 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide.

Molecular Properties

• Compound Name: 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide
• PubChem CID: 161122587
• Molecular Formula: C126H110Cl2F6N14O18
• Molecular Weight: 2293.24 g/mol
• Exact Mass: 2290.74
• IUPAC Name: 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide
• SMILES: COc1cc2c(Oc3ccc4c(C(=O)Nc5cc(C)on5)cccc4c3)ccnc2cc1OCC1(N(C)C)CC1.COc1cc2c(Oc3ccc4c(C(=O)Nc5cc(C)on5)cccc4c3)ccnc2cc1OCC1(N)CC1.COc1cc2c(Oc3ccc4c(C(=O)Nc5ccc(Cl)c(C(F)(F)F)c5)cccc4c3)ccnc2cc1OCC1(N(C)C)CC1.COc1cc2c(Oc3ccc4c(C(=O)Nc5ccc(Cl)c(C(F)(F)F)c5)cccc4c3)ccnc2cc1OCC1(N)CC1
• InChI: InChI=1S/C34H29ClF3N3O4.C32H25ClF3N3O4.C31H30N4O5.C29H26N4O5/c1-41(2)33(12-13-33)19-44-31-18-28-25(17-30(31)43-3)29(11-14-39-28)45-22-8-9-23-20(15-22)5-4-6-24(23)32(42)40-21-7-10-27(35)26(16-21)34(36,37)38;1-41-28-15-23-26(16-29(28)42-17-31(37)10-11-31)38-12-9-27(23)43-20-6-7-21-18(13-20)3-2-4-22(21)30(40)39-19-5-8-25(33)24(14-19)32(34,35)36;1-19-14-29(34-40-19)33-30(36)23-7-5-6-20-15-21(8-9-22(20)23)39-26-10-13-32-25-17-28(27(37-4)16-24(25)26)38-18-31(11-12-31)35(2)3;1-17-12-27(33-38-17)32-28(34)21-5-3-4-18-13-19(6-7-20(18)21)37-24-8-11-31-23-15-26(25(35-2)14-22(23)24)36-16-29(30)9-10-29/h4-11,14-18H,12-13,19H2,1-3H3,(H,40,42);2-9,12-16H,10-11,17,37H2,1H3,(H,39,40);5-10,13-17H,11-12,18H2,1-4H3,(H,33,34,36);3-8,11-15H,9-10,16,30H2,1-2H3,(H,32,33,34)
• InChIKey: ULDJEJASWGYFCO-UHFFFAOYSA-N
• XLogP: 28.39
• TPSA: 389.30 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 28
• Rotatable Bonds: 34
• Heavy Atoms: 166
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2293.24
LogP ≤ 5	28.39
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	28

Frequently Asked Questions

What is the IUPAC name of 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide?

The IUPAC name of 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide (CID 161122587) is 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide.

What is the SMILES notation for 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide?

The canonical SMILES for 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide is COc1cc2c(Oc3ccc4c(C(=O)Nc5cc(C)on5)cccc4c3)ccnc2cc1OCC1(N(C)C)CC1.COc1cc2c(Oc3ccc4c(C(=O)Nc5cc(C)on5)cccc4c3)ccnc2cc1OCC1(N)CC1.COc1cc2c(Oc3ccc4c(C(=O)Nc5ccc(Cl)c(C(F)(F)F)c5)cccc4c3)ccnc2cc1OCC1(N(C)C)CC1.COc1cc2c(Oc3ccc4c(C(=O)Nc5ccc(Cl)c(C(F)(F)F)c5)cccc4c3)ccnc2cc1OCC1(N)CC1.

What is the InChIKey of 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide?

The InChIKey is ULDJEJASWGYFCO-UHFFFAOYSA-N. The full InChI is InChI=1S/C34H29ClF3N3O4.C32H25ClF3N3O4.C31H30N4O5.C29H26N4O5/c1-41(2)33(12-13-33)19-44-31-18-28-25(17-30(31)43-3)29(11-14-39-28)45-22-8-9-23-20(15-22)5-4-6-24(23)32(42)40-21-7-10-27(35)26(16-21)34(36,37)38;1-41-28-15-23-26(16-29(28)42-17-31(37)10-11-31)38-12-9-27(23)43-20-6-7-21-18(13-20)3-2-4-22(21)30(40)39-19-5-8-25(33)24(14-19)32(34,35)36;1-19-14-29(34-40-19)33-30(36)23-7-5-6-20-15-21(8-9-22(20)23)39-26-10-13-32-25-17-28(27(37-4)16-24(25)26)38-18-31(11-12-31)35(2)3;1-17-12-27(33-38-17)32-28(34)21-5-3-4-18-13-19(6-7-20(18)21)37-24-8-11-31-23-15-26(25(35-2)14-22(23)24)36-16-29(30)9-10-29/h4-11,14-18H,12-13,19H2,1-3H3,(H,40,42);2-9,12-16H,10-11,17,37H2,1H3,(H,39,40);5-10,13-17H,11-12,18H2,1-4H3,(H,33,34,36);3-8,11-15H,9-10,16,30H2,1-2H3,(H,32,33,34).

What are the key properties of 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide?

6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide has a molecular weight of 2293.24 g/mol, XLogP of 28.39, 34 rotatable bonds, 6 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-[4-chloro-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide;6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide;N-[4-chloro-3-(trifluoromethyl)phenyl]-6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalene-1-carboxamide;6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-(5-methyl-1,2-oxazol-3-yl)naphthalene-1-carboxamide is sourced from PubChem (CID 161122587), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).