2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one

C209H227F12N29O24 — CID 161126634

IUPAC2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one
SMILESCCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)(C)F)c3)ccc2C)cc1=O.CCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)ccc2C)cc1=O.CCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)C)c3)ccc2C)cc1=O.CCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(F)(F)CC)c3)ccc2C)cc1=O.Cc1ccc(C(=O)Cc2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2ccccc2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOC[C@H]2C)n(C)c(=O)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOC[C@H]2C)n(C)c(=O)c1
InChIInChI=1S/C27H30F2N4O3.C27H31FN4O3.C27H32N4O3.C26H25F3N2O3.2C26H28F2N4O3.C25H27F2N5O3.C25H26N2O3/c1-4-27(28,29)23-14-19(8-9-30-23)26(35)31-21-7-6-18(3)22(17-21)20-15-24(32-10-12-36-13-11-32)33(5-2)25(34)16-20;1-5-32-24(31-10-12-35-13-11-31)15-20(16-25(32)33)22-17-21(7-6-18(22)2)30-26(34)19-8-9-29-23(14-19)27(3,4)28;1-5-31-25(30-10-12-34-13-11-30)15-21(16-26(31)32)23-17-22(7-6-19(23)4)29-27(33)20-8-9-28-24(14-20)18(2)3;1-17-6-7-19(23(32)13-18-4-3-5-21(12-18)26(27,28)29)14-22(17)20-15-24(30(2)25(33)16-20)31-8-10-34-11-9-31;1-16-5-6-20(30-25(34)18-7-8-29-22(11-18)26(3,27)28)14-21(16)19-12-23(31(4)24(33)13-19)32-9-10-35-15-17(32)2;1-4-32-23(31-9-11-35-12-10-31)14-19(15-24(32)33)21-16-20(6-5-17(21)2)30-25(34)18-7-8-29-22(13-18)26(3,27)28;1-15-14-35-8-7-32(15)22-10-18(11-23(33)31(22)4)20-12-19(13-29-16(20)2)30-24(34)17-5-6-28-21(9-17)25(3,26)27;1-18-8-9-20(23(28)14-19-6-4-3-5-7-19)15-22(18)21-16-24(26(2)25(29)17-21)27-10-12-30-13-11-27/h6-9,14-17H,4-5,10-13H2,1-3H3,(H,31,35);6-9,14-17H,5,10-13H2,1-4H3,(H,30,34);6-9,14-18H,5,10-13H2,1-4H3,(H,29,33);3-7,12,14-16H,8-11,13H2,1-2H3;5-8,11-14,17H,9-10,15H2,1-4H3,(H,30,34);5-8,13-16H,4,9-12H2,1-3H3,(H,30,34);5-6,9-13,15H,7-8,14H2,1-4H3,(H,30,34);3-9,15-17H,10-14H2,1-2H3/t;;;;17-;;15-;/m....1.1./s1
InChIKeyULQKAKULKWIBSK-JQEOEFGISA-N
MW3757.27 g/mol
LogP34.60
Rot. Bonds45

About 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one

2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one (PubChem CID 161126634) has the molecular formula C209H227F12N29O24 and a molecular weight of 3757.27 g/mol. Its IUPAC name is 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one.

Molecular Properties

Compound Name2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one
PubChem CID161126634
Molecular FormulaC209H227F12N29O24
Molecular Weight3757.27 g/mol
Exact Mass3754.72
IUPAC Name2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one
SMILESCCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)(C)F)c3)ccc2C)cc1=O.CCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)ccc2C)cc1=O.CCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)C)c3)ccc2C)cc1=O.CCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(F)(F)CC)c3)ccc2C)cc1=O.Cc1ccc(C(=O)Cc2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2ccccc2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOC[C@H]2C)n(C)c(=O)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOC[C@H]2C)n(C)c(=O)c1
InChIInChI=1S/C27H30F2N4O3.C27H31FN4O3.C27H32N4O3.C26H25F3N2O3.2C26H28F2N4O3.C25H27F2N5O3.C25H26N2O3/c1-4-27(28,29)23-14-19(8-9-30-23)26(35)31-21-7-6-18(3)22(17-21)20-15-24(32-10-12-36-13-11-32)33(5-2)25(34)16-20;1-5-32-24(31-10-12-35-13-11-31)15-20(16-25(32)33)22-17-21(7-6-18(22)2)30-26(34)19-8-9-29-23(14-19)27(3,4)28;1-5-31-25(30-10-12-34-13-11-30)15-21(16-26(31)32)23-17-22(7-6-19(23)4)29-27(33)20-8-9-28-24(14-20)18(2)3;1-17-6-7-19(23(32)13-18-4-3-5-21(12-18)26(27,28)29)14-22(17)20-15-24(30(2)25(33)16-20)31-8-10-34-11-9-31;1-16-5-6-20(30-25(34)18-7-8-29-22(11-18)26(3,27)28)14-21(16)19-12-23(31(4)24(33)13-19)32-9-10-35-15-17(32)2;1-4-32-23(31-9-11-35-12-10-31)14-19(15-24(32)33)21-16-20(6-5-17(21)2)30-25(34)18-7-8-29-22(13-18)26(3,27)28;1-15-14-35-8-7-32(15)22-10-18(11-23(33)31(22)4)20-12-19(13-29-16(20)2)30-24(34)17-5-6-28-21(9-17)25(3,26)27;1-18-8-9-20(23(28)14-19-6-4-3-5-7-19)15-22(18)21-16-24(26(2)25(29)17-21)27-10-12-30-13-11-27/h6-9,14-17H,4-5,10-13H2,1-3H3,(H,31,35);6-9,14-17H,5,10-13H2,1-4H3,(H,30,34);6-9,14-18H,5,10-13H2,1-4H3,(H,29,33);3-7,12,14-16H,8-11,13H2,1-2H3;5-8,11-14,17H,9-10,15H2,1-4H3,(H,30,34);5-8,13-16H,4,9-12H2,1-3H3,(H,30,34);5-6,9-13,15H,7-8,14H2,1-4H3,(H,30,34);3-9,15-17H,10-14H2,1-2H3/t;;;;17-;;15-;/m....1.1./s1
InChIKeyULQKAKULKWIBSK-JQEOEFGISA-N
XLogP34.60
TPSA574.73 Ų
H-Bond Donors6
H-Bond Acceptors47
Rotatable Bonds45
Heavy Atoms274
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003757.27
LogP ≤ 534.60
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1047

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'dyes5A(27)', 'substructure': 'N/A'}

Analyze 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one with MolForge

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Launch Full Analysis

Related Compounds

US11377431, Example 38
CID 163255657
US11377431, Example 39
CID 163255634
1-N-carbamoyl-3-N-methyl-3-N-(2-morpholin-4-ylethyl)-2-phenyl-4-pyridin-2-yl-1-N-(2,2,2-trifluoro-1-phenylethyl)benzene-1,3-dicarboxamide
CID 67518411
2-(1,1-difluoroethyl)-N-[3-[2-ethoxy-6-[2-[[methyl-[4-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]pyridin-3-yl]-6-morpholin-4-ylpyrimidin-2-yl]amino]methyl]morpholin-4-yl]pyrimidin-4-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 130425772
2-[4-(5-aminopyrazin-2-yl)-3-fluorophenyl]-N-tert-butyl-5-(trifluoromethyl)benzamide;[3-[4-(5-aminopyrazin-2-yl)-3-fluorophenyl]pyridin-2-yl]-morpholin-4-ylmethanone
CID 138678138
N-[3-[7-(2-aminoethyl)-1-benzyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-methylbenzamide;N-[3-[7-(2-aminoethyl)-1-[2-(dimethylamino)ethyl]-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-methylbenzamide;N-[3-[7-(2-aminoethyl)-2-oxo-1-propyl-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-methylbenzamide;N-[3-[7-(3-aminopropyl)-1-(2-morpholin-4-ylethyl)-2-oxo-1,6-naphthyridin-3-yl]-2-fluoro-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[5-[7-(3-aminopropyl)-1-(2-morpholin-4-ylethyl)-2-oxo-1,6-naphthyridin-3-yl]-2-fluoro-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-(3-aminopropyl)-1-(2-morpholin-4-ylethyl)-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzamide;1-(benzenesulfonyl)-3-[3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]urea;N-[3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]benzenesulfonamide;methane
CID 157078104
2-tert-butyl-N-[3-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-methylphenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(4-ethylpiperazin-1-yl)-N-[4-methyl-3-(2-morpholin-4-yl-4-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;1-[4-methyl-3-(4-morpholin-4-yl-2-pyridinyl)phenyl]-2-[3-(trifluoromethyl)phenyl]ethanone
CID 157217069
N-[3-[(4aR,5R)-5-(hydroxymethyl)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[3-[(4aS,5R)-5-(hydroxymethyl)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[3-[(4aR,5S)-5-(hydroxymethyl)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[3-[(4aS,5S)-5-(hydroxymethyl)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-[5-(hydroxymethyl)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl]-4-methylphenyl]pyridine-4-carboxamide;N-[5-[5-(hydroxymethyl)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157238667
N-[3-(8-ethyl-9-oxo-13-oxa-1,6,8-triazatricyclo[9.4.0.02,7]pentadeca-2(7),3,5-trien-4-yl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;bis(N-[3-(8-ethyl-9-oxo-12-oxa-1,6,8-triazatricyclo[8.4.0.02,7]tetradeca-2(7),3,5-trien-4-yl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide);N-[3-[(10S)-8-ethyl-9-oxo-12-oxa-1,6,8-triazatricyclo[8.4.0.02,7]tetradeca-2(7),3,5-trien-4-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[3-[(10R)-8-ethyl-9-oxo-12-oxa-1,6,8-triazatricyclo[8.4.0.02,7]tetradeca-2(7),3,5-trien-4-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[4-methyl-3-(9-oxo-12-oxa-1,6,8-triazatricyclo[8.4.0.02,7]tetradeca-2(7),3,5-trien-4-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157285251
methane;methyl (2S)-2-[[2,6-difluoro-4-[(3R)-3-(2,2,2-trifluoroethyl)morpholin-4-yl]benzoyl]amino]-3-[8-[1,6-dimethyl-2-oxo-4-(trifluoromethyl)-3-pyridinyl]quinolin-5-yl]propanoate;methyl (2S)-2-[[2,6-difluoro-4-[(3R)-3-(trifluoromethyl)morpholin-4-yl]benzoyl]amino]-3-[8-[5-(dimethylamino)-1,6-dimethyl-2-oxo-3-pyridinyl]quinolin-5-yl]propanoate;methyl (2S)-2-[[2,6-difluoro-4-[(3S)-3-(trifluoromethyl)morpholin-4-yl]benzoyl]amino]-3-[8-(4,5,6-trimethyl-3-oxopyrazin-2-yl)quinolin-5-yl]propanoate
CID 157285609
N-[3-[2-[bis(2-hydroxyethyl)amino]-6-(oxan-4-yl)-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[3-[2-(2-hydroxyethylamino)-6-(oxan-4-yl)-4-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[2-(2-hydroxyethylamino)-6-(oxan-4-yl)-4-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[5-[2-(2-hydroxyethylamino)-6-(oxan-4-yl)-4-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-[2-(2-hydroxyethylamino)-6-(oxan-4-yl)-4-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157288435
2-(2-amino-5-piperidin-1-ylphenyl)-N-[[3-(trifluoromethyl)phenyl]methyl]pyridine-4-carboxamide;3-N-methyl-3-N-(2-morpholin-4-ylethyl)-1-N-[4-piperidin-1-yl-2-[4-[[3-(trifluoromethyl)phenyl]methylcarbamoyl]-2-pyridinyl]phenyl]benzene-1,3-dicarboxamide;hydrochloride
CID 157295099

Frequently Asked Questions

What is the IUPAC name of 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one?
The IUPAC name of 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one (CID 161126634) is 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one.
What is the SMILES notation for 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one?
The canonical SMILES for 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one is CCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)(C)F)c3)ccc2C)cc1=O.CCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)ccc2C)cc1=O.CCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)C)c3)ccc2C)cc1=O.CCn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(F)(F)CC)c3)ccc2C)cc1=O.Cc1ccc(C(=O)Cc2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2ccccc2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOC[C@H]2C)n(C)c(=O)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOC[C@H]2C)n(C)c(=O)c1.
What is the InChIKey of 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one?
The InChIKey is ULQKAKULKWIBSK-JQEOEFGISA-N. The full InChI is InChI=1S/C27H30F2N4O3.C27H31FN4O3.C27H32N4O3.C26H25F3N2O3.2C26H28F2N4O3.C25H27F2N5O3.C25H26N2O3/c1-4-27(28,29)23-14-19(8-9-30-23)26(35)31-21-7-6-18(3)22(17-21)20-15-24(32-10-12-36-13-11-32)33(5-2)25(34)16-20;1-5-32-24(31-10-12-35-13-11-31)15-20(16-25(32)33)22-17-21(7-6-18(22)2)30-26(34)19-8-9-29-23(14-19)27(3,4)28;1-5-31-25(30-10-12-34-13-11-30)15-21(16-26(31)32)23-17-22(7-6-19(23)4)29-27(33)20-8-9-28-24(14-20)18(2)3;1-17-6-7-19(23(32)13-18-4-3-5-21(12-18)26(27,28)29)14-22(17)20-15-24(30(2)25(33)16-20)31-8-10-34-11-9-31;1-16-5-6-20(30-25(34)18-7-8-29-22(11-18)26(3,27)28)14-21(16)19-12-23(31(4)24(33)13-19)32-9-10-35-15-17(32)2;1-4-32-23(31-9-11-35-12-10-31)14-19(15-24(32)33)21-16-20(6-5-17(21)2)30-25(34)18-7-8-29-22(13-18)26(3,27)28;1-15-14-35-8-7-32(15)22-10-18(11-23(33)31(22)4)20-12-19(13-29-16(20)2)30-24(34)17-5-6-28-21(9-17)25(3,26)27;1-18-8-9-20(23(28)14-19-6-4-3-5-7-19)15-22(18)21-16-24(26(2)25(29)17-21)27-10-12-30-13-11-27/h6-9,14-17H,4-5,10-13H2,1-3H3,(H,31,35);6-9,14-17H,5,10-13H2,1-4H3,(H,30,34);6-9,14-18H,5,10-13H2,1-4H3,(H,29,33);3-7,12,14-16H,8-11,13H2,1-2H3;5-8,11-14,17H,9-10,15H2,1-4H3,(H,30,34);5-8,13-16H,4,9-12H2,1-3H3,(H,30,34);5-6,9-13,15H,7-8,14H2,1-4H3,(H,30,34);3-9,15-17H,10-14H2,1-2H3/t;;;;17-;;15-;/m....1.1./s1.
What are the key properties of 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one?
2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one has a molecular weight of 3757.27 g/mol, XLogP of 34.60, 45 rotatable bonds, 6 hydrogen bond donors, and 47 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(1,1-difluoroethyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[1-methyl-2-[(3R)-3-methylmorpholin-4-yl]-6-oxo-4-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(1-ethyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-4-methylphenyl]-2-propan-2-ylpyridine-4-carboxamide;1-methyl-4-[2-methyl-5-(2-phenylacetyl)phenyl]-6-morpholin-4-ylpyridin-2-one;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one is sourced from PubChem (CID 161126634), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).