4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine

C125H126F6N28O6S2 — CID 161138657

About 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine

4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine (PubChem CID 161138657) has the molecular formula C125H126F6N28O6S2 and a molecular weight of 2294.69 g/mol. Its IUPAC name is 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine.

Molecular Properties

• Compound Name: 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine
• PubChem CID: 161138657
• Molecular Formula: C125H126F6N28O6S2
• Molecular Weight: 2294.69 g/mol
• Exact Mass: 2292.98
• IUPAC Name: 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine
• SMILES: Cn1c2c(c3cc(F)ccc31)CN(c1ccc(N3CCOCC3)nc1)CC2.Fc1ccc2[nH]c3c(c2c1)CN(c1cc2sc(N4CCOCC4)nc2cn1)CC3.Fc1ccc2[nH]c3c(c2c1)CN(c1ncc2nc(N4CCOCC4)sc2n1)CC3.Fc1ccc2c3c([nH]c2c1)CCN(c1ccc(N2CCOCC2)cn1)C3.Fc1ccc2c3c([nH]c2c1)CCN(c1ccc2ccc(N4CCOCC4)nc2c1)C3.Fc1ccc2c3c([nH]c2c1)CCN(c1cnc(N2CCOCC2)cn1)C3
• InChI: InChI=1S/C24H23FN4O.C21H20FN5OS.C21H23FN4O.C20H19FN6OS.C20H21FN4O.C19H20FN5O/c25-17-3-5-19-20-15-29(8-7-21(20)26-23(19)13-17)18-4-1-16-2-6-24(27-22(16)14-18)28-9-11-30-12-10-28;22-13-1-2-16-14(9-13)15-12-27(4-3-17(15)24-16)20-10-19-18(11-23-20)25-21(29-19)26-5-7-28-8-6-26;1-24-19-4-2-15(22)12-17(19)18-14-26(7-6-20(18)24)16-3-5-21(23-13-16)25-8-10-27-11-9-25;21-12-1-2-15-13(9-12)14-11-27(4-3-16(14)23-15)19-22-10-17-18(25-19)29-20(24-17)26-5-7-28-8-6-26;21-14-1-3-16-17-13-25(6-5-18(17)23-19(16)11-14)20-4-2-15(12-22-20)24-7-9-26-10-8-24;20-13-1-2-14-15-12-25(4-3-16(15)23-17(14)9-13)19-11-21-18(10-22-19)24-5-7-26-8-6-24/h1-6,13-14,26H,7-12,15H2;1-2,9-11,24H,3-8,12H2;2-5,12-13H,6-11,14H2,1H3;1-2,9-10,23H,3-8,11H2;1-4,11-12,23H,5-10,13H2;1-2,9-11,23H,3-8,12H2
• InChIKey: UNDFTGWBEKGEBU-UHFFFAOYSA-N
• XLogP: 19.78
• TPSA: 307.04 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 31
• Rotatable Bonds: 12
• Heavy Atoms: 167
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2294.69
LogP ≤ 5	19.78
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	31

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'indol_3yl_alk(461)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine?

The IUPAC name of 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine (CID 161138657) is 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine.

What is the SMILES notation for 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine?

The canonical SMILES for 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine is Cn1c2c(c3cc(F)ccc31)CN(c1ccc(N3CCOCC3)nc1)CC2.Fc1ccc2[nH]c3c(c2c1)CN(c1cc2sc(N4CCOCC4)nc2cn1)CC3.Fc1ccc2[nH]c3c(c2c1)CN(c1ncc2nc(N4CCOCC4)sc2n1)CC3.Fc1ccc2c3c([nH]c2c1)CCN(c1ccc(N2CCOCC2)cn1)C3.Fc1ccc2c3c([nH]c2c1)CCN(c1ccc2ccc(N4CCOCC4)nc2c1)C3.Fc1ccc2c3c([nH]c2c1)CCN(c1cnc(N2CCOCC2)cn1)C3.

What is the InChIKey of 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine?

The InChIKey is UNDFTGWBEKGEBU-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H23FN4O.C21H20FN5OS.C21H23FN4O.C20H19FN6OS.C20H21FN4O.C19H20FN5O/c25-17-3-5-19-20-15-29(8-7-21(20)26-23(19)13-17)18-4-1-16-2-6-24(27-22(16)14-18)28-9-11-30-12-10-28;22-13-1-2-16-14(9-13)15-12-27(4-3-17(15)24-16)20-10-19-18(11-23-20)25-21(29-19)26-5-7-28-8-6-26;1-24-19-4-2-15(22)12-17(19)18-14-26(7-6-20(18)24)16-3-5-21(23-13-16)25-8-10-27-11-9-25;21-12-1-2-15-13(9-12)14-11-27(4-3-16(14)23-15)19-22-10-17-18(25-19)29-20(24-17)26-5-7-28-8-6-26;21-14-1-3-16-17-13-25(6-5-18(17)23-19(16)11-14)20-4-2-15(12-22-20)24-7-9-26-10-8-24;20-13-1-2-14-15-12-25(4-3-16(15)23-17(14)9-13)19-11-21-18(10-22-19)24-5-7-26-8-6-24/h1-6,13-14,26H,7-12,15H2;1-2,9-11,24H,3-8,12H2;2-5,12-13H,6-11,14H2,1H3;1-2,9-10,23H,3-8,11H2;1-4,11-12,23H,5-10,13H2;1-2,9-11,23H,3-8,12H2.

What are the key properties of 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine?

4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine has a molecular weight of 2294.69 g/mol, XLogP of 19.78, 12 rotatable bonds, 5 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 4-[5-(8-fluoro-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-2-pyridinyl]morpholine;4-[5-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)pyrazin-2-yl]morpholine;4-[6-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-3-pyridinyl]morpholine;4-[7-(7-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)quinolin-2-yl]morpholine;4-[6-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]morpholine;4-[5-(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]morpholine is sourced from PubChem (CID 161138657), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).