2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide

C102H89F2N23O12S2 — CID 161146354

About 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide

2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide (PubChem CID 161146354) has the molecular formula C102H89F2N23O12S2 and a molecular weight of 1931.11 g/mol. Its IUPAC name is 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide.

Molecular Properties

• Compound Name: 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide
• PubChem CID: 161146354
• Molecular Formula: C102H89F2N23O12S2
• Molecular Weight: 1931.11 g/mol
• Exact Mass: 1929.65
• IUPAC Name: 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide
• SMILES: C.C.CC(F)(F)c1nc(C(=O)Nc2cncc(Oc3cncnc3)c2)cs1.Cc1cccc(C(=O)Nc2cc(Oc3cccnc3)ccn2)c1.Cc1cccc(C(=O)Nc2cc(Oc3cccnc3)ncn2)c1.Cc1cccc(C(=O)Nc2cccc(Oc3ccc(C)nc3)n2)c1.Cc1cccc(C(=O)Nc2cccc(Oc3cccnc3)n2)c1.O=C(Nc1cncc(Oc2cncnc2)c1)c1cscn1
• InChI: InChI=1S/C19H17N3O2.2C18H15N3O2.C17H14N4O2.C15H11F2N5O2S.C13H9N5O2S.2CH4/c1-13-5-3-6-15(11-13)19(23)22-17-7-4-8-18(21-17)24-16-10-9-14(2)20-12-16;1-13-5-2-6-14(11-13)18(22)21-16-8-3-9-17(20-16)23-15-7-4-10-19-12-15;1-13-4-2-5-14(10-13)18(22)21-17-11-15(7-9-20-17)23-16-6-3-8-19-12-16;1-12-4-2-5-13(8-12)17(22)21-15-9-16(20-11-19-15)23-14-6-3-7-18-10-14;1-15(16,17)14-22-12(7-25-14)13(23)21-9-2-10(4-18-3-9)24-11-5-19-8-20-6-11;19-13(12-6-21-8-17-12)18-9-1-10(3-14-2-9)20-11-4-15-7-16-5-11;;/h3-12H,1-2H3,(H,21,22,23);2*2-12H,1H3,(H,20,21,22);2-11H,1H3,(H,19,20,21,22);2-8H,1H3,(H,21,23);1-8H,(H,18,19);2*1H4
• InChIKey: UOCJBGZRRTUFGN-UHFFFAOYSA-N
• XLogP: 22.15
• TPSA: 449.11 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 31
• Rotatable Bonds: 25
• Heavy Atoms: 141
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1931.11
LogP ≤ 5	22.15
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide?

The IUPAC name of 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide (CID 161146354) is 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide.

What is the SMILES notation for 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide?

The canonical SMILES for 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide is C.C.CC(F)(F)c1nc(C(=O)Nc2cncc(Oc3cncnc3)c2)cs1.Cc1cccc(C(=O)Nc2cc(Oc3cccnc3)ccn2)c1.Cc1cccc(C(=O)Nc2cc(Oc3cccnc3)ncn2)c1.Cc1cccc(C(=O)Nc2cccc(Oc3ccc(C)nc3)n2)c1.Cc1cccc(C(=O)Nc2cccc(Oc3cccnc3)n2)c1.O=C(Nc1cncc(Oc2cncnc2)c1)c1cscn1.

What is the InChIKey of 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide?

The InChIKey is UOCJBGZRRTUFGN-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H17N3O2.2C18H15N3O2.C17H14N4O2.C15H11F2N5O2S.C13H9N5O2S.2CH4/c1-13-5-3-6-15(11-13)19(23)22-17-7-4-8-18(21-17)24-16-10-9-14(2)20-12-16;1-13-5-2-6-14(11-13)18(22)21-16-8-3-9-17(20-16)23-15-7-4-10-19-12-15;1-13-4-2-5-14(10-13)18(22)21-17-11-15(7-9-20-17)23-16-6-3-8-19-12-16;1-12-4-2-5-13(8-12)17(22)21-15-9-16(20-11-19-15)23-14-6-3-7-18-10-14;1-15(16,17)14-22-12(7-25-14)13(23)21-9-2-10(4-18-3-9)24-11-5-19-8-20-6-11;19-13(12-6-21-8-17-12)18-9-1-10(3-14-2-9)20-11-4-15-7-16-5-11;;/h3-12H,1-2H3,(H,21,22,23);2*2-12H,1H3,(H,20,21,22);2-11H,1H3,(H,19,20,21,22);2-8H,1H3,(H,21,23);1-8H,(H,18,19);2*1H4.

What are the key properties of 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide?

2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide has a molecular weight of 1931.11 g/mol, XLogP of 22.15, 25 rotatable bonds, 6 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;3-methyl-N-[6-[(6-methyl-3-pyridinyl)oxy]-2-pyridinyl]benzamide;3-methyl-N-(4-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxy-2-pyridinyl)benzamide;3-methyl-N-(6-pyridin-3-yloxypyrimidin-4-yl)benzamide;N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide is sourced from PubChem (CID 161146354), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).