3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine

C125H156F2N40O6S — CID 161168600

IUPAC3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine
SMILESCC1(C)CC(Oc2ccc(-c3ccc(-c4cn[nH]c4)[nH]c3=O)nn2)CC(C)(C)N1.CC1(C)CC(Oc2ccc(-c3nc(-c4cn[nH]c4)ncc3N)nn2)CC(C)(C)N1.CN(c1ccc(-c2c(F)cc(-c3cn[nH]c3)cc2F)nn1)C1CC(C)(C)NC(C)(C)C1.CN(c1ccc(-c2ccc(-c3cn[nH]c3)[nH]c2=O)nn1)C1CC(C)(C)NC(C)(C)C1.CN(c1nnc(Oc2cccc(-c3cn[nH]c3)c2)s1)C1CC(C)(C)NC(C)(C)C1.O=c1[nH]c(-c2cn[nH]c2)ccc1-c1ccc(N2CC3(CCNC3)C2)nn1
InChIInChI=1S/C23H28F2N6.C22H29N7O.C21H26N6O2.C21H28N6OS.C20H26N8O.C18H19N7O/c1-22(2)10-16(11-23(3,4)30-22)31(5)20-7-6-19(28-29-20)21-17(24)8-14(9-18(21)25)15-12-26-27-13-15;1-21(2)10-15(11-22(3,4)28-21)29(5)19-9-8-18(26-27-19)16-6-7-17(25-20(16)30)14-12-23-24-13-14;1-20(2)9-14(10-21(3,4)27-20)29-18-8-7-17(25-26-18)15-5-6-16(24-19(15)28)13-11-22-23-12-13;1-20(2)10-16(11-21(3,4)26-20)27(5)18-24-25-19(29-18)28-17-8-6-7-14(9-17)15-12-22-23-13-15;1-19(2)7-13(8-20(3,4)28-19)29-16-6-5-15(26-27-16)17-14(21)11-22-18(25-17)12-9-23-24-10-12;26-17-13(1-2-14(22-17)12-7-20-21-8-12)15-3-4-16(24-23-15)25-10-18(11-25)5-6-19-9-18/h6-9,12-13,16,30H,10-11H2,1-5H3,(H,26,27);6-9,12-13,15,28H,10-11H2,1-5H3,(H,23,24)(H,25,30);5-8,11-12,14,27H,9-10H2,1-4H3,(H,22,23)(H,24,28);6-9,12-13,16,26H,10-11H2,1-5H3,(H,22,23);5-6,9-11,13,28H,7-8,21H2,1-4H3,(H,23,24);1-4,7-8,19H,5-6,9-11H2,(H,20,21)(H,22,26)
InChIKeyUQWPDTZGHIKKOF-UHFFFAOYSA-N
MW2384.96 g/mol
LogP18.52
Rot. Bonds24

About 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine

3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine (PubChem CID 161168600) has the molecular formula C125H156F2N40O6S and a molecular weight of 2384.96 g/mol. Its IUPAC name is 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine.

Molecular Properties

Compound Name3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine
PubChem CID161168600
Molecular FormulaC125H156F2N40O6S
Molecular Weight2384.96 g/mol
Exact Mass2383.28
IUPAC Name3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine
SMILESCC1(C)CC(Oc2ccc(-c3ccc(-c4cn[nH]c4)[nH]c3=O)nn2)CC(C)(C)N1.CC1(C)CC(Oc2ccc(-c3nc(-c4cn[nH]c4)ncc3N)nn2)CC(C)(C)N1.CN(c1ccc(-c2c(F)cc(-c3cn[nH]c3)cc2F)nn1)C1CC(C)(C)NC(C)(C)C1.CN(c1ccc(-c2ccc(-c3cn[nH]c3)[nH]c2=O)nn1)C1CC(C)(C)NC(C)(C)C1.CN(c1nnc(Oc2cccc(-c3cn[nH]c3)c2)s1)C1CC(C)(C)NC(C)(C)C1.O=c1[nH]c(-c2cn[nH]c2)ccc1-c1ccc(N2CC3(CCNC3)C2)nn1
InChIInChI=1S/C23H28F2N6.C22H29N7O.C21H26N6O2.C21H28N6OS.C20H26N8O.C18H19N7O/c1-22(2)10-16(11-23(3,4)30-22)31(5)20-7-6-19(28-29-20)21-17(24)8-14(9-18(21)25)15-12-26-27-13-15;1-21(2)10-15(11-22(3,4)28-21)29(5)19-9-8-18(26-27-19)16-6-7-17(25-20(16)30)14-12-23-24-13-14;1-20(2)9-14(10-21(3,4)27-20)29-18-8-7-17(25-26-18)15-5-6-16(24-19(15)28)13-11-22-23-12-13;1-20(2)10-16(11-21(3,4)26-20)27(5)18-24-25-19(29-18)28-17-8-6-7-14(9-17)15-12-22-23-13-15;1-19(2)7-13(8-20(3,4)28-19)29-16-6-5-15(26-27-16)17-14(21)11-22-18(25-17)12-9-23-24-10-12;26-17-13(1-2-14(22-17)12-7-20-21-8-12)15-3-4-16(24-23-15)25-10-18(11-25)5-6-19-9-18/h6-9,12-13,16,30H,10-11H2,1-5H3,(H,26,27);6-9,12-13,15,28H,10-11H2,1-5H3,(H,23,24)(H,25,30);5-8,11-12,14,27H,9-10H2,1-4H3,(H,22,23)(H,24,28);6-9,12-13,16,26H,10-11H2,1-5H3,(H,22,23);5-6,9-11,13,28H,7-8,21H2,1-4H3,(H,23,24);1-4,7-8,19H,5-6,9-11H2,(H,20,21)(H,22,26)
InChIKeyUQWPDTZGHIKKOF-UHFFFAOYSA-N
XLogP18.52
TPSA589.97 Ų
H-Bond Donors16
H-Bond Acceptors38
Rotatable Bonds24
Heavy Atoms174
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002384.96
LogP ≤ 518.52
H-Bond Donors ≤ 516
H-Bond Acceptors ≤ 1038

Analyze 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

3-[4-(1,1-difluoroethoxy)phenyl]-1-[5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]-2-pyridinyl]propan-1-one;N-[(1S)-1-(4-ethoxyphenyl)ethyl]-3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]pyridine-2-carboxamide;3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(6-pyrazol-1-yl-3-pyridinyl)methyl]pyridine-2-carboxamide;5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]methyl]pyridine-2-carboxamide;5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[[6-(4-methylpyrazol-1-yl)-3-pyridinyl]methyl]pyridine-2-carboxamide
CID 157956965
6-[3,5-Dimethyl-1-(1-methyltetrazol-5-yl)pyrazol-4-yl]-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-methylsulfanylpiperidin-4-yl)pyrido[2,3-d]pyrimidin-7-one;6-[2-fluoro-4-(2-methyltetrazol-5-yl)phenyl]-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-[[2-(trifluoromethyl)phenyl]methyl]pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-2-(2-methyl-1,5-dihydropyrazol-3-yl)pyrimidin-5-yl]-8-[2-[methyl(methylsulfanyl)amino]ethyl]-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(2-methylpyrazol-3-yl)-3-pyridinyl]-2-[4-[(1-methylpyrrolidin-3-yl)methyl]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;tetrahydrate
CID 159060425
CID 160965532
CID 160965532
3-[4-(1,1-difluoroethoxy)phenyl]-1-[5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]-2-pyridinyl]propan-1-one;N-[(1R)-1-(4-ethoxyphenyl)ethyl]-3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]pyridine-2-carboxamide;N-[(1S)-1-(4-ethoxyphenyl)ethyl]-3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]pyridine-2-carboxamide;3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(6-pyrazol-1-yl-3-pyridinyl)methyl]pyridine-2-carboxamide;5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[[5-(4-methylpyrazol-1-yl)pyrazin-2-yl]methyl]pyridine-2-carboxamide;5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[[6-(4-methylpyrazol-1-yl)-3-pyridinyl]methyl]pyridine-2-carboxamide
CID 164985706
CID 165107533
CID 165107533
2-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-5-(1H-pyrazol-4-yl)phenol;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one
CID 157160646
2-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-5-(1H-pyrazol-4-yl)phenol;3-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine
CID 157185954
6-[2-(difluoromethyl)-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;3-[2-(difluoromethyl)-4-(1H-pyrazol-4-yl)phenyl]-6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;N-methyl-5-[4-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one
CID 158714238
7-(2-ethoxyethyl)-3-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]-7-methyl-5H-pyrrolo[2,3-e][1,2,4]triazin-6-one;4-(6-ethoxy-3-pyridinyl)-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]-5,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-6-one;2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]-5,5-dimethyl-4-(1H-pyrazol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-6-one
CID 159782575
2-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-5-(1H-pyrazol-4-yl)phenol;3-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine
CID 160545413
N-[(1R)-1-(4-ethoxyphenyl)ethyl]-3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]pyridine-2-carboxamide;N-[(1S)-1-(4-ethoxyphenyl)ethyl]-3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]pyridine-2-carboxamide;N-[[4-(1-fluoroethoxy)phenyl]methyl]-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]pyridine-2-carboxamide;3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(6-pyrazol-1-yl-3-pyridinyl)methyl]pyridine-2-carboxamide;5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[[6-(3-methylpyrrol-1-yl)-3-pyridinyl]methyl]pyridine-2-carboxamide;5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(4-propan-2-yloxyphenyl)methyl]pyridine-2-carboxamide
CID 161211004
N-[(1R)-1-(4-ethoxyphenyl)ethyl]-3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]pyridine-2-carboxamide;N-[(1S)-1-(4-ethoxyphenyl)ethyl]-3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]pyridine-2-carboxamide;N-[[4-(1-fluoroethoxy)phenyl]methyl]-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]pyridine-2-carboxamide;3-methyl-5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(6-pyrazol-1-yl-3-pyridinyl)methyl]pyridine-2-carboxamide;5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[[6-(4-methylpyrazol-1-yl)-3-pyridinyl]methyl]pyridine-2-carboxamide;5-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-2-yl]-N-[(4-propan-2-yloxyphenyl)methyl]pyridine-2-carboxamide
CID 161741912

Frequently Asked Questions

What is the IUPAC name of 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine?
The IUPAC name of 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine (CID 161168600) is 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine.
What is the SMILES notation for 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine?
The canonical SMILES for 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine is CC1(C)CC(Oc2ccc(-c3ccc(-c4cn[nH]c4)[nH]c3=O)nn2)CC(C)(C)N1.CC1(C)CC(Oc2ccc(-c3nc(-c4cn[nH]c4)ncc3N)nn2)CC(C)(C)N1.CN(c1ccc(-c2c(F)cc(-c3cn[nH]c3)cc2F)nn1)C1CC(C)(C)NC(C)(C)C1.CN(c1ccc(-c2ccc(-c3cn[nH]c3)[nH]c2=O)nn1)C1CC(C)(C)NC(C)(C)C1.CN(c1nnc(Oc2cccc(-c3cn[nH]c3)c2)s1)C1CC(C)(C)NC(C)(C)C1.O=c1[nH]c(-c2cn[nH]c2)ccc1-c1ccc(N2CC3(CCNC3)C2)nn1.
What is the InChIKey of 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine?
The InChIKey is UQWPDTZGHIKKOF-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H28F2N6.C22H29N7O.C21H26N6O2.C21H28N6OS.C20H26N8O.C18H19N7O/c1-22(2)10-16(11-23(3,4)30-22)31(5)20-7-6-19(28-29-20)21-17(24)8-14(9-18(21)25)15-12-26-27-13-15;1-21(2)10-15(11-22(3,4)28-21)29(5)19-9-8-18(26-27-19)16-6-7-17(25-20(16)30)14-12-23-24-13-14;1-20(2)9-14(10-21(3,4)27-20)29-18-8-7-17(25-26-18)15-5-6-16(24-19(15)28)13-11-22-23-12-13;1-20(2)10-16(11-21(3,4)26-20)27(5)18-24-25-19(29-18)28-17-8-6-7-14(9-17)15-12-22-23-13-15;1-19(2)7-13(8-20(3,4)28-19)29-16-6-5-15(26-27-16)17-14(21)11-22-18(25-17)12-9-23-24-10-12;26-17-13(1-2-14(22-17)12-7-20-21-8-12)15-3-4-16(24-23-15)25-10-18(11-25)5-6-19-9-18/h6-9,12-13,16,30H,10-11H2,1-5H3,(H,26,27);6-9,12-13,15,28H,10-11H2,1-5H3,(H,23,24)(H,25,30);5-8,11-12,14,27H,9-10H2,1-4H3,(H,22,23)(H,24,28);6-9,12-13,16,26H,10-11H2,1-5H3,(H,22,23);5-6,9-11,13,28H,7-8,21H2,1-4H3,(H,23,24);1-4,7-8,19H,5-6,9-11H2,(H,20,21)(H,22,26).
What are the key properties of 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine?
3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine has a molecular weight of 2384.96 g/mol, XLogP of 18.52, 24 rotatable bonds, 16 hydrogen bond donors, and 38 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[6-(2,7-diazaspiro[3.4]octan-2-yl)pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-[2,6-difluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine;N-methyl-5-[3-(1H-pyrazol-4-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-6-(1H-pyrazol-4-yl)-1H-pyridin-2-one;6-(1H-pyrazol-4-yl)-3-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]-1H-pyridin-2-one;2-(1H-pyrazol-4-yl)-4-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyrimidin-5-amine is sourced from PubChem (CID 161168600), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).