(5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione

C204H167BrCl3F4N49O50 — CID 161173390

IUPAC(5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione
SMILESCOc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4c(C(F)(F)F)nc(N)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4c(C)nc(N)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(C)ncc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(Cl)ncc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(F)ncc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cnc(Cl)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cnc(NC(C)C)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cnc(NC5CC5)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cncc(Br)c4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1Cl)C(=O)N(C[C@@]1(c3cc4cnccc4o3)NC(=O)NC1=O)C2
InChIInChI=1S/C22H20N6O5.C22H22N6O5.C21H18N4O5.C20H15BrN4O5.2C20H15ClN4O5.C20H15F3N6O5.C20H15FN4O5.C20H18N6O5.C19H14ClN5O5/c1-32-14-5-2-11-9-28(18(29)15(11)7-14)10-22(19(30)26-21(31)27-22)16-6-12-8-23-20(24-13-3-4-13)25-17(12)33-16;1-11(2)24-20-23-8-13-6-16(33-17(13)25-20)22(19(30)26-21(31)27-22)10-28-9-12-4-5-14(32-3)7-15(12)18(28)29;1-11-5-13-6-17(30-16(13)8-22-11)21(19(27)23-20(28)24-21)10-25-9-12-3-4-14(29-2)7-15(12)18(25)26;1-29-12-3-2-10-8-25(17(26)13(10)5-12)9-20(18(27)23-19(28)24-20)15-4-11-6-22-7-14(21)16(11)30-15;1-29-12-3-2-10-8-25(17(26)13(10)6-12)9-20(18(27)23-19(28)24-20)15-4-11-5-16(21)22-7-14(11)30-15;1-29-13-3-2-10-8-25(17(26)15(10)16(13)21)9-20(18(27)23-19(28)24-20)14-6-11-7-22-5-4-12(11)30-14;1-33-9-3-2-8-6-29(15(30)10(8)4-9)7-19(16(31)27-18(32)28-19)12-5-11-13(20(21,22)23)25-17(24)26-14(11)34-12;1-29-12-3-2-10-8-25(17(26)13(10)6-12)9-20(18(27)23-19(28)24-20)15-4-11-5-16(21)22-7-14(11)30-15;1-9-12-6-14(31-15(12)23-18(21)22-9)20(17(28)24-19(29)25-20)8-26-7-10-3-4-11(30-2)5-13(10)16(26)27;1-29-11-3-2-9-7-25(15(26)12(9)5-11)8-19(16(27)23-18(28)24-19)13-4-10-6-21-17(20)22-14(10)30-13/h2,5-8,13H,3-4,9-10H2,1H3,(H,23,24,25)(H2,26,27,30,31);4-8,11H,9-10H2,1-3H3,(H,23,24,25)(H2,26,27,30,31);3-8H,9-10H2,1-2H3,(H2,23,24,27,28);3*2-7H,8-9H2,1H3,(H2,23,24,27,28);2-5H,6-7H2,1H3,(H2,24,25,26)(H2,27,28,31,32);2-7H,8-9H2,1H3,(H2,23,24,27,28);3-6H,7-8H2,1-2H3,(H2,21,22,23)(H2,24,25,28,29);2-6H,7-8H2,1H3,(H2,23,24,27,28)/t2*22-;21-;3*20-;19-;2*20-;19-/m0000000000/s1
InChIKeyURMGRRPIVHYAFC-LQHHUTHGSA-N
MW4367.13 g/mol
LogP17.30
Rot. Bonds44

About (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione

(5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione (PubChem CID 161173390) has the molecular formula C204H167BrCl3F4N49O50 and a molecular weight of 4367.13 g/mol. Its IUPAC name is (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione.

Molecular Properties

Compound Name(5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione
PubChem CID161173390
Molecular FormulaC204H167BrCl3F4N49O50
Molecular Weight4367.13 g/mol
Exact Mass4362.02
IUPAC Name(5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione
SMILESCOc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4c(C(F)(F)F)nc(N)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4c(C)nc(N)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(C)ncc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(Cl)ncc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(F)ncc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cnc(Cl)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cnc(NC(C)C)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cnc(NC5CC5)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cncc(Br)c4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1Cl)C(=O)N(C[C@@]1(c3cc4cnccc4o3)NC(=O)NC1=O)C2
InChIInChI=1S/C22H20N6O5.C22H22N6O5.C21H18N4O5.C20H15BrN4O5.2C20H15ClN4O5.C20H15F3N6O5.C20H15FN4O5.C20H18N6O5.C19H14ClN5O5/c1-32-14-5-2-11-9-28(18(29)15(11)7-14)10-22(19(30)26-21(31)27-22)16-6-12-8-23-20(24-13-3-4-13)25-17(12)33-16;1-11(2)24-20-23-8-13-6-16(33-17(13)25-20)22(19(30)26-21(31)27-22)10-28-9-12-4-5-14(32-3)7-15(12)18(28)29;1-11-5-13-6-17(30-16(13)8-22-11)21(19(27)23-20(28)24-21)10-25-9-12-3-4-14(29-2)7-15(12)18(25)26;1-29-12-3-2-10-8-25(17(26)13(10)5-12)9-20(18(27)23-19(28)24-20)15-4-11-6-22-7-14(21)16(11)30-15;1-29-12-3-2-10-8-25(17(26)13(10)6-12)9-20(18(27)23-19(28)24-20)15-4-11-5-16(21)22-7-14(11)30-15;1-29-13-3-2-10-8-25(17(26)15(10)16(13)21)9-20(18(27)23-19(28)24-20)14-6-11-7-22-5-4-12(11)30-14;1-33-9-3-2-8-6-29(15(30)10(8)4-9)7-19(16(31)27-18(32)28-19)12-5-11-13(20(21,22)23)25-17(24)26-14(11)34-12;1-29-12-3-2-10-8-25(17(26)13(10)6-12)9-20(18(27)23-19(28)24-20)15-4-11-5-16(21)22-7-14(11)30-15;1-9-12-6-14(31-15(12)23-18(21)22-9)20(17(28)24-19(29)25-20)8-26-7-10-3-4-11(30-2)5-13(10)16(26)27;1-29-11-3-2-9-7-25(15(26)12(9)5-11)8-19(16(27)23-18(28)24-19)13-4-10-6-21-17(20)22-14(10)30-13/h2,5-8,13H,3-4,9-10H2,1H3,(H,23,24,25)(H2,26,27,30,31);4-8,11H,9-10H2,1-3H3,(H,23,24,25)(H2,26,27,30,31);3-8H,9-10H2,1-2H3,(H2,23,24,27,28);3*2-7H,8-9H2,1H3,(H2,23,24,27,28);2-5H,6-7H2,1H3,(H2,24,25,26)(H2,27,28,31,32);2-7H,8-9H2,1H3,(H2,23,24,27,28);3-6H,7-8H2,1-2H3,(H2,21,22,23)(H2,24,25,28,29);2-6H,7-8H2,1H3,(H2,23,24,27,28)/t2*22-;21-;3*20-;19-;2*20-;19-/m0000000000/s1
InChIKeyURMGRRPIVHYAFC-LQHHUTHGSA-N
XLogP17.30
TPSA1278.25 Ų
H-Bond Donors24
H-Bond Acceptors69
Rotatable Bonds44
Heavy Atoms311
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004367.13
LogP ≤ 517.30
H-Bond Donors ≤ 524
H-Bond Acceptors ≤ 1069

Analyze (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione with MolForge

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What is the IUPAC name of (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione?
The IUPAC name of (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione (CID 161173390) is (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione.
What is the SMILES notation for (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione?
The canonical SMILES for (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione is COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4c(C(F)(F)F)nc(N)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4c(C)nc(N)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(C)ncc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(Cl)ncc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cc(F)ncc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cnc(Cl)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cnc(NC(C)C)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cnc(NC5CC5)nc4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3cc4cncc(Br)c4o3)NC(=O)NC1=O)C2.COc1ccc2c(c1Cl)C(=O)N(C[C@@]1(c3cc4cnccc4o3)NC(=O)NC1=O)C2.
What is the InChIKey of (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione?
The InChIKey is URMGRRPIVHYAFC-LQHHUTHGSA-N. The full InChI is InChI=1S/C22H20N6O5.C22H22N6O5.C21H18N4O5.C20H15BrN4O5.2C20H15ClN4O5.C20H15F3N6O5.C20H15FN4O5.C20H18N6O5.C19H14ClN5O5/c1-32-14-5-2-11-9-28(18(29)15(11)7-14)10-22(19(30)26-21(31)27-22)16-6-12-8-23-20(24-13-3-4-13)25-17(12)33-16;1-11(2)24-20-23-8-13-6-16(33-17(13)25-20)22(19(30)26-21(31)27-22)10-28-9-12-4-5-14(32-3)7-15(12)18(28)29;1-11-5-13-6-17(30-16(13)8-22-11)21(19(27)23-20(28)24-21)10-25-9-12-3-4-14(29-2)7-15(12)18(25)26;1-29-12-3-2-10-8-25(17(26)13(10)5-12)9-20(18(27)23-19(28)24-20)15-4-11-6-22-7-14(21)16(11)30-15;1-29-12-3-2-10-8-25(17(26)13(10)6-12)9-20(18(27)23-19(28)24-20)15-4-11-5-16(21)22-7-14(11)30-15;1-29-13-3-2-10-8-25(17(26)15(10)16(13)21)9-20(18(27)23-19(28)24-20)14-6-11-7-22-5-4-12(11)30-14;1-33-9-3-2-8-6-29(15(30)10(8)4-9)7-19(16(31)27-18(32)28-19)12-5-11-13(20(21,22)23)25-17(24)26-14(11)34-12;1-29-12-3-2-10-8-25(17(26)13(10)6-12)9-20(18(27)23-19(28)24-20)15-4-11-5-16(21)22-7-14(11)30-15;1-9-12-6-14(31-15(12)23-18(21)22-9)20(17(28)24-19(29)25-20)8-26-7-10-3-4-11(30-2)5-13(10)16(26)27;1-29-11-3-2-9-7-25(15(26)12(9)5-11)8-19(16(27)23-18(28)24-19)13-4-10-6-21-17(20)22-14(10)30-13/h2,5-8,13H,3-4,9-10H2,1H3,(H,23,24,25)(H2,26,27,30,31);4-8,11H,9-10H2,1-3H3,(H,23,24,25)(H2,26,27,30,31);3-8H,9-10H2,1-2H3,(H2,23,24,27,28);3*2-7H,8-9H2,1H3,(H2,23,24,27,28);2-5H,6-7H2,1H3,(H2,24,25,26)(H2,27,28,31,32);2-7H,8-9H2,1H3,(H2,23,24,27,28);3-6H,7-8H2,1-2H3,(H2,21,22,23)(H2,24,25,28,29);2-6H,7-8H2,1H3,(H2,23,24,27,28)/t2*22-;21-;3*20-;19-;2*20-;19-/m0000000000/s1.
What are the key properties of (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione?
(5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione has a molecular weight of 4367.13 g/mol, XLogP of 17.30, 44 rotatable bonds, 24 hydrogen bond donors, and 69 hydrogen bond acceptors.
Where does this data come from?
All data for (5S)-5-(2-amino-4-methylfuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[2-amino-4-(trifluoromethyl)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(7-bromofuro[3,2-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-chlorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(2-chlorofuro[2,3-d]pyrimidin-6-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(4-chloro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-furo[3,2-c]pyridin-2-ylimidazolidine-2,4-dione;(5S)-5-[2-(cyclopropylamino)furo[2,3-d]pyrimidin-6-yl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-(5-fluorofuro[2,3-c]pyridin-2-yl)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(5-methylfuro[2,3-c]pyridin-2-yl)imidazolidine-2,4-dione;(5S)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[2-(propan-2-ylamino)furo[2,3-d]pyrimidin-6-yl]imidazolidine-2,4-dione is sourced from PubChem (CID 161173390), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).