N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile

C168H166F3N35O6S — CID 161174157

About N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile

N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile (PubChem CID 161174157) has the molecular formula C168H166F3N35O6S and a molecular weight of 2860.48 g/mol. Its IUPAC name is N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile.

Molecular Properties

• Compound Name: N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile
• PubChem CID: 161174157
• Molecular Formula: C168H166F3N35O6S
• Molecular Weight: 2860.48 g/mol
• Exact Mass: 2858.34
• IUPAC Name: N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile
• SMILES: CC(C)(C)C(=O)Nc1ccc(-c2cnn3cccc(N4CCC(C#N)CC4)c23)cc1.Cc1cc(C)n(-c2ccc(-c3cnn4cccc(N5CCC(C#N)CC5)c34)cc2)n1.Cc1ccn2ncc(-c3ccc(-c4cnn(C)c4)cc3)c2c1C1=CCC(C#N)CC1.N#CC1CCN(c2cccn3ncc(-c4ccc(S(=O)(=O)N5CCOCC5)cc4)c23)CC1.N#CC1CCN(c2cccn3ncc(-c4cccc(OCC(F)(F)F)c4)c23)CC1.N#CC1CCN(c2cccn3ncc(-c4cccc(OCc5ccccc5)c4)c23)CC1.[C-]#[N+]C1CC2CCC(C1)N2c1cccn2ncc(-c3ccc(-c4cnn(C)c4)cc3)c12
• InChI: InChI=1S/C26H24N4O.C25H24N6.C25H23N5.C24H24N6.C24H27N5O.C23H25N5O3S.C21H19F3N4O/c27-17-20-11-14-29(15-12-20)25-10-5-13-30-26(25)24(18-28-30)22-8-4-9-23(16-22)31-19-21-6-2-1-3-7-21;1-26-20-12-21-9-10-22(13-20)31(21)24-4-3-11-30-25(24)23(15-28-30)18-7-5-17(6-8-18)19-14-27-29(2)16-19;1-17-11-12-30-25(24(17)21-5-3-18(13-26)4-6-21)23(15-28-30)20-9-7-19(8-10-20)22-14-27-29(2)16-22;1-17-14-18(2)30(27-17)21-7-5-20(6-8-21)22-16-26-29-11-3-4-23(24(22)29)28-12-9-19(15-25)10-13-28;1-24(2,3)23(30)27-19-8-6-18(7-9-19)20-16-26-29-12-4-5-21(22(20)29)28-13-10-17(15-25)11-14-28;24-16-18-7-10-26(11-8-18)22-2-1-9-28-23(22)21(17-25-28)19-3-5-20(6-4-19)32(29,30)27-12-14-31-15-13-27;22-21(23,24)14-29-17-4-1-3-16(11-17)18-13-26-28-8-2-5-19(20(18)28)27-9-6-15(12-25)7-10-27/h1-10,13,16,18,20H,11-12,14-15,19H2;3-8,11,14-16,20-22H,9-10,12-13H2,2H3;5,7-12,14-16,18H,3-4,6H2,1-2H3;3-8,11,14,16,19H,9-10,12-13H2,1-2H3;4-9,12,16-17H,10-11,13-14H2,1-3H3,(H,27,30);1-6,9,17-18H,7-8,10-15H2;1-5,8,11,13,15H,6-7,9-10,14H2
• InChIKey: URORULRXDSBPFH-UHFFFAOYSA-N
• XLogP: 32.27
• TPSA: 435.27 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 38
• Rotatable Bonds: 25
• Heavy Atoms: 213
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2860.48
LogP ≤ 5	32.27
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	38

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Carbo_cation/anion', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile?

The IUPAC name of N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile (CID 161174157) is N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile.

What is the SMILES notation for N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile?

The canonical SMILES for N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile is CC(C)(C)C(=O)Nc1ccc(-c2cnn3cccc(N4CCC(C#N)CC4)c23)cc1.Cc1cc(C)n(-c2ccc(-c3cnn4cccc(N5CCC(C#N)CC5)c34)cc2)n1.Cc1ccn2ncc(-c3ccc(-c4cnn(C)c4)cc3)c2c1C1=CCC(C#N)CC1.N#CC1CCN(c2cccn3ncc(-c4ccc(S(=O)(=O)N5CCOCC5)cc4)c23)CC1.N#CC1CCN(c2cccn3ncc(-c4cccc(OCC(F)(F)F)c4)c23)CC1.N#CC1CCN(c2cccn3ncc(-c4cccc(OCc5ccccc5)c4)c23)CC1.[C-]#[N+]C1CC2CCC(C1)N2c1cccn2ncc(-c3ccc(-c4cnn(C)c4)cc3)c12.

What is the InChIKey of N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile?

The InChIKey is URORULRXDSBPFH-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H24N4O.C25H24N6.C25H23N5.C24H24N6.C24H27N5O.C23H25N5O3S.C21H19F3N4O/c27-17-20-11-14-29(15-12-20)25-10-5-13-30-26(25)24(18-28-30)22-8-4-9-23(16-22)31-19-21-6-2-1-3-7-21;1-26-20-12-21-9-10-22(13-20)31(21)24-4-3-11-30-25(24)23(15-28-30)18-7-5-17(6-8-18)19-14-27-29(2)16-19;1-17-11-12-30-25(24(17)21-5-3-18(13-26)4-6-21)23(15-28-30)20-9-7-19(8-10-20)22-14-27-29(2)16-22;1-17-14-18(2)30(27-17)21-7-5-20(6-8-21)22-16-26-29-11-3-4-23(24(22)29)28-12-9-19(15-25)10-13-28;1-24(2,3)23(30)27-19-8-6-18(7-9-19)20-16-26-29-12-4-5-21(22(20)29)28-13-10-17(15-25)11-14-28;24-16-18-7-10-26(11-8-18)22-2-1-9-28-23(22)21(17-25-28)19-3-5-20(6-4-19)32(29,30)27-12-14-31-15-13-27;22-21(23,24)14-29-17-4-1-3-16(11-17)18-13-26-28-8-2-5-19(20(18)28)27-9-6-15(12-25)7-10-27/h1-10,13,16,18,20H,11-12,14-15,19H2;3-8,11,14-16,20-22H,9-10,12-13H2,2H3;5,7-12,14-16,18H,3-4,6H2,1-2H3;3-8,11,14,16,19H,9-10,12-13H2,1-2H3;4-9,12,16-17H,10-11,13-14H2,1-3H3,(H,27,30);1-6,9,17-18H,7-8,10-15H2;1-5,8,11,13,15H,6-7,9-10,14H2.

What are the key properties of N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile?

N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile has a molecular weight of 2860.48 g/mol, XLogP of 32.27, 25 rotatable bonds, 1 hydrogen bond donors, and 38 hydrogen bond acceptors.

Where does this data come from?

All data for N-[4-[4-(4-cyanopiperidin-1-yl)pyrazolo[1,5-a]pyridin-3-yl]phenyl]-2,2-dimethylpropanamide;1-[3-[4-(3,5-dimethylpyrazol-1-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;4-(3-isocyano-8-azabicyclo[3.2.1]octan-8-yl)-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridine;4-[5-methyl-3-[4-(1-methylpyrazol-4-yl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]cyclohex-3-ene-1-carbonitrile;1-[3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-(3-phenylmethoxyphenyl)pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile;1-[3-[3-(2,2,2-trifluoroethoxy)phenyl]pyrazolo[1,5-a]pyridin-4-yl]piperidine-4-carbonitrile is sourced from PubChem (CID 161174157), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).