3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide

C148H167F14N27O12 — CID 161174484

IUPAC3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide
SMILESCCC(=O)Cc1cc(Oc2cc(C(=O)Nc3ccc(CN4CCN(CC)CC4)c(C(F)(F)F)c3)ccc2C)ncn1.CCN1CCN(Cc2ccc(CC(=O)c3ccc(C)c(Oc4cc(Nc5cnn(C)c5)ncn4)c3)cc2C(C)(F)F)CC1.CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4cc(C)ncn4)c3)cc2C(F)(F)F)CC1.CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4cc(CC(=O)C5CC5)ncn4)c3)cc2C(F)(F)F)CC1.CCc1cc(Oc2cc(C(=O)Nc3ccc(CN4CCN(CC)CC4)c(C(F)(F)F)c3)ccc2C)ncn1
InChIInChI=1S/C32H37F2N7O2.C31H34F3N5O3.C30H34F3N5O3.C28H32F3N5O2.C27H30F3N5O2/c1-5-40-10-12-41(13-11-40)19-25-9-7-23(14-27(25)32(3,33)34)15-28(42)24-8-6-22(2)29(16-24)43-31-17-30(35-21-36-31)38-26-18-37-39(4)20-26;1-3-38-10-12-39(13-11-38)18-23-8-9-24(15-26(23)31(32,33)34)37-30(41)22-5-4-20(2)28(14-22)42-29-17-25(35-19-36-29)16-27(40)21-6-7-21;1-4-25(39)15-24-17-28(35-19-34-24)41-27-14-21(7-6-20(27)3)29(40)36-23-9-8-22(26(16-23)30(31,32)33)18-38-12-10-37(5-2)11-13-38;1-4-22-16-26(33-18-32-22)38-25-14-20(7-6-19(25)3)27(37)34-23-9-8-21(24(15-23)28(29,30)31)17-36-12-10-35(5-2)11-13-36;1-4-34-9-11-35(12-10-34)16-21-7-8-22(15-23(21)27(28,29)30)33-26(36)20-6-5-18(2)24(14-20)37-25-13-19(3)31-17-32-25/h6-9,14,16-18,20-21H,5,10-13,15,19H2,1-4H3,(H,35,36,38);4-5,8-9,14-15,17,19,21H,3,6-7,10-13,16,18H2,1-2H3,(H,37,41);6-9,14,16-17,19H,4-5,10-13,15,18H2,1-3H3,(H,36,40);6-9,14-16,18H,4-5,10-13,17H2,1-3H3,(H,34,37);5-8,13-15,17H,4,9-12,16H2,1-3H3,(H,33,36)
InChIKeyURPSZHNAXKHEGR-UHFFFAOYSA-N
MW2782.11 g/mol
LogP27.59
Rot. Bonds46

About 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide

3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide (PubChem CID 161174484) has the molecular formula C148H167F14N27O12 and a molecular weight of 2782.11 g/mol. Its IUPAC name is 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide.

Molecular Properties

Compound Name3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide
PubChem CID161174484
Molecular FormulaC148H167F14N27O12
Molecular Weight2782.11 g/mol
Exact Mass2780.31
IUPAC Name3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide
SMILESCCC(=O)Cc1cc(Oc2cc(C(=O)Nc3ccc(CN4CCN(CC)CC4)c(C(F)(F)F)c3)ccc2C)ncn1.CCN1CCN(Cc2ccc(CC(=O)c3ccc(C)c(Oc4cc(Nc5cnn(C)c5)ncn4)c3)cc2C(C)(F)F)CC1.CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4cc(C)ncn4)c3)cc2C(F)(F)F)CC1.CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4cc(CC(=O)C5CC5)ncn4)c3)cc2C(F)(F)F)CC1.CCc1cc(Oc2cc(C(=O)Nc3ccc(CN4CCN(CC)CC4)c(C(F)(F)F)c3)ccc2C)ncn1
InChIInChI=1S/C32H37F2N7O2.C31H34F3N5O3.C30H34F3N5O3.C28H32F3N5O2.C27H30F3N5O2/c1-5-40-10-12-41(13-11-40)19-25-9-7-23(14-27(25)32(3,33)34)15-28(42)24-8-6-22(2)29(16-24)43-31-17-30(35-21-36-31)38-26-18-37-39(4)20-26;1-3-38-10-12-39(13-11-38)18-23-8-9-24(15-26(23)31(32,33)34)37-30(41)22-5-4-20(2)28(14-22)42-29-17-25(35-19-36-29)16-27(40)21-6-7-21;1-4-25(39)15-24-17-28(35-19-34-24)41-27-14-21(7-6-20(27)3)29(40)36-23-9-8-22(26(16-23)30(31,32)33)18-38-12-10-37(5-2)11-13-38;1-4-22-16-26(33-18-32-22)38-25-14-20(7-6-19(25)3)27(37)34-23-9-8-21(24(15-23)28(29,30)31)17-36-12-10-35(5-2)11-13-36;1-4-34-9-11-35(12-10-34)16-21-7-8-22(15-23(21)27(28,29)30)33-26(36)20-6-5-18(2)24(14-20)37-25-13-19(3)31-17-32-25/h6-9,14,16-18,20-21H,5,10-13,15,19H2,1-4H3,(H,35,36,38);4-5,8-9,14-15,17,19,21H,3,6-7,10-13,16,18H2,1-2H3,(H,37,41);6-9,14,16-17,19H,4-5,10-13,15,18H2,1-3H3,(H,36,40);6-9,14-16,18H,4-5,10-13,17H2,1-3H3,(H,34,37);5-8,13-15,17H,4,9-12,16H2,1-3H3,(H,33,36)
InChIKeyURPSZHNAXKHEGR-UHFFFAOYSA-N
XLogP27.59
TPSA404.91 Ų
H-Bond Donors5
H-Bond Acceptors35
Rotatable Bonds46
Heavy Atoms201
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002782.11
LogP ≤ 527.59
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1035

Analyze 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide?
The IUPAC name of 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide (CID 161174484) is 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide.
What is the SMILES notation for 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide?
The canonical SMILES for 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide is CCC(=O)Cc1cc(Oc2cc(C(=O)Nc3ccc(CN4CCN(CC)CC4)c(C(F)(F)F)c3)ccc2C)ncn1.CCN1CCN(Cc2ccc(CC(=O)c3ccc(C)c(Oc4cc(Nc5cnn(C)c5)ncn4)c3)cc2C(C)(F)F)CC1.CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4cc(C)ncn4)c3)cc2C(F)(F)F)CC1.CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4cc(CC(=O)C5CC5)ncn4)c3)cc2C(F)(F)F)CC1.CCc1cc(Oc2cc(C(=O)Nc3ccc(CN4CCN(CC)CC4)c(C(F)(F)F)c3)ccc2C)ncn1.
What is the InChIKey of 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide?
The InChIKey is URPSZHNAXKHEGR-UHFFFAOYSA-N. The full InChI is InChI=1S/C32H37F2N7O2.C31H34F3N5O3.C30H34F3N5O3.C28H32F3N5O2.C27H30F3N5O2/c1-5-40-10-12-41(13-11-40)19-25-9-7-23(14-27(25)32(3,33)34)15-28(42)24-8-6-22(2)29(16-24)43-31-17-30(35-21-36-31)38-26-18-37-39(4)20-26;1-3-38-10-12-39(13-11-38)18-23-8-9-24(15-26(23)31(32,33)34)37-30(41)22-5-4-20(2)28(14-22)42-29-17-25(35-19-36-29)16-27(40)21-6-7-21;1-4-25(39)15-24-17-28(35-19-34-24)41-27-14-21(7-6-20(27)3)29(40)36-23-9-8-22(26(16-23)30(31,32)33)18-38-12-10-37(5-2)11-13-38;1-4-22-16-26(33-18-32-22)38-25-14-20(7-6-19(25)3)27(37)34-23-9-8-21(24(15-23)28(29,30)31)17-36-12-10-35(5-2)11-13-36;1-4-34-9-11-35(12-10-34)16-21-7-8-22(15-23(21)27(28,29)30)33-26(36)20-6-5-18(2)24(14-20)37-25-13-19(3)31-17-32-25/h6-9,14,16-18,20-21H,5,10-13,15,19H2,1-4H3,(H,35,36,38);4-5,8-9,14-15,17,19,21H,3,6-7,10-13,16,18H2,1-2H3,(H,37,41);6-9,14,16-17,19H,4-5,10-13,15,18H2,1-3H3,(H,36,40);6-9,14-16,18H,4-5,10-13,17H2,1-3H3,(H,34,37);5-8,13-15,17H,4,9-12,16H2,1-3H3,(H,33,36).
What are the key properties of 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide?
3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide has a molecular weight of 2782.11 g/mol, XLogP of 27.59, 46 rotatable bonds, 5 hydrogen bond donors, and 35 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[6-(2-cyclopropyl-2-oxoethyl)pyrimidin-4-yl]oxy-N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide;2-[3-(1,1-difluoroethyl)-4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-1-[4-methyl-3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]ethanone;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-(6-ethylpyrimidin-4-yl)oxy-4-methylbenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(6-methylpyrimidin-4-yl)oxybenzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[6-(2-oxobutyl)pyrimidin-4-yl]oxybenzamide is sourced from PubChem (CID 161174484), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).