5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine

C85H89ClF6N24O5 — CID 161229581

About 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine

5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine (PubChem CID 161229581) has the molecular formula C85H89ClF6N24O5 and a molecular weight of 1676.25 g/mol. Its IUPAC name is 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine.

Molecular Properties

• Compound Name: 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine
• PubChem CID: 161229581
• Molecular Formula: C85H89ClF6N24O5
• Molecular Weight: 1676.25 g/mol
• Exact Mass: 1674.70
• IUPAC Name: 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine
• SMILES: COc1cc(-c2cncn2C)ccc1Nc1cc(Cc2cnc(C)c(C)n2)nc2c1N=C(C(F)F)C2.COc1cc(-c2cncn2C)ccc1Nc1cc(Cc2cnc(C)c(C)n2)nc2c1nc(C(F)F)n2C1CCCCO1.COc1cc(-c2cncn2C)ccc1Nc1cc(Cl)nc2c1nc(C(F)F)n2C1CCCCO1.Cc1ncc(N)nc1C
• InChI: InChI=1S/C30H32F2N8O2.C26H25F2N7O.C23H23ClF2N6O2.C6H9N3/c1-17-18(2)35-21(14-34-17)12-20-13-23(37-22-9-8-19(11-25(22)41-4)24-15-33-16-39(24)3)27-29(36-20)40(30(38-27)28(31)32)26-7-5-6-10-42-26;1-14-15(2)31-18(11-30-14)8-17-9-20(25-21(32-17)10-22(34-25)26(27)28)33-19-6-5-16(7-24(19)36-4)23-12-29-13-35(23)3;1-31-12-27-11-16(31)13-6-7-14(17(9-13)33-2)28-15-10-18(24)29-22-20(15)30-23(21(25)26)32(22)19-5-3-4-8-34-19;1-4-5(2)9-6(7)3-8-4/h8-9,11,13-16,26,28H,5-7,10,12H2,1-4H3,(H,36,37);5-7,9,11-13,26H,8,10H2,1-4H3,(H,32,33);6-7,9-12,19,21H,3-5,8H2,1-2H3,(H,28,29);3H,1-2H3,(H2,7,9)
• InChIKey: UYOPLWZWCKHRRG-UHFFFAOYSA-N
• XLogP: 17.89
• TPSA: 325.73 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 29
• Rotatable Bonds: 21
• Heavy Atoms: 121
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1676.25
LogP ≤ 5	17.89
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine?

The IUPAC name of 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine (CID 161229581) is 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine.

What is the SMILES notation for 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine?

The canonical SMILES for 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine is COc1cc(-c2cncn2C)ccc1Nc1cc(Cc2cnc(C)c(C)n2)nc2c1N=C(C(F)F)C2.COc1cc(-c2cncn2C)ccc1Nc1cc(Cc2cnc(C)c(C)n2)nc2c1nc(C(F)F)n2C1CCCCO1.COc1cc(-c2cncn2C)ccc1Nc1cc(Cl)nc2c1nc(C(F)F)n2C1CCCCO1.Cc1ncc(N)nc1C.

What is the InChIKey of 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine?

The InChIKey is UYOPLWZWCKHRRG-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H32F2N8O2.C26H25F2N7O.C23H23ClF2N6O2.C6H9N3/c1-17-18(2)35-21(14-34-17)12-20-13-23(37-22-9-8-19(11-25(22)41-4)24-15-33-16-39(24)3)27-29(36-20)40(30(38-27)28(31)32)26-7-5-6-10-42-26;1-14-15(2)31-18(11-30-14)8-17-9-20(25-21(32-17)10-22(34-25)26(27)28)33-19-6-5-16(7-24(19)36-4)23-12-29-13-35(23)3;1-31-12-27-11-16(31)13-6-7-14(17(9-13)33-2)28-15-10-18(24)29-22-20(15)30-23(21(25)26)32(22)19-5-3-4-8-34-19;1-4-5(2)9-6(7)3-8-4/h8-9,11,13-16,26,28H,5-7,10,12H2,1-4H3,(H,36,37);5-7,9,11-13,26H,8,10H2,1-4H3,(H,32,33);6-7,9-12,19,21H,3-5,8H2,1-2H3,(H,28,29);3H,1-2H3,(H2,7,9).

What are the key properties of 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine?

5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine has a molecular weight of 1676.25 g/mol, XLogP of 17.89, 21 rotatable bonds, 4 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 5-chloro-2-(difluoromethyl)-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3-(oxan-2-yl)imidazo[4,5-b]pyridin-7-amine;2-(difluoromethyl)-5-[(5,6-dimethylpyrazin-2-yl)methyl]-N-[2-methoxy-4-(3-methylimidazol-4-yl)phenyl]-3H-pyrrolo[3,2-b]pyridin-7-amine;5,6-dimethylpyrazin-2-amine is sourced from PubChem (CID 161229581), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).