N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide

C125H106F6N18O15 — CID 161248656

IUPACN-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide
SMILESCn1ccc(C(=O)NCc2ccc(OCc3ccccc3F)cc2)cc1=O.Cn1cccc(C(=O)NCc2ccc(OCc3ccccc3F)cc2)c1=O.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1cc[nH]c(=O)c1.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1cccc2ncnn12.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1cccn2ncnc12.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1ccn2ncnc2c1
InChIInChI=1S/3C21H17FN4O2.2C21H19FN2O3.C20H17FN2O3/c22-19-6-2-1-4-16(19)13-28-17-9-7-15(8-10-17)12-23-21(27)18-5-3-11-26-20(18)24-14-25-26;22-18-5-2-1-4-16(18)13-28-17-10-8-15(9-11-17)12-23-21(27)19-6-3-7-20-24-14-25-26(19)20;22-19-4-2-1-3-17(19)13-28-18-7-5-15(6-8-18)12-23-21(27)16-9-10-26-20(11-16)24-14-25-26;1-24-12-4-6-18(21(24)26)20(25)23-13-15-8-10-17(11-9-15)27-14-16-5-2-3-7-19(16)22;1-24-11-10-16(12-20(24)25)21(26)23-13-15-6-8-18(9-7-15)27-14-17-4-2-3-5-19(17)22;21-18-4-2-1-3-16(18)13-26-17-7-5-14(6-8-17)12-23-20(25)15-9-10-22-19(24)11-15/h3*1-11,14H,12-13H2,(H,23,27);2-12H,13-14H2,1H3,(H,23,25);2-12H,13-14H2,1H3,(H,23,26);1-11H,12-13H2,(H,22,24)(H,23,25)
InChIKeyVAYXZMPBRDLWRZ-UHFFFAOYSA-N
MW2214.32 g/mol
LogP19.22
Rot. Bonds36

About N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide

N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide (PubChem CID 161248656) has the molecular formula C125H106F6N18O15 and a molecular weight of 2214.32 g/mol. Its IUPAC name is N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide.

Molecular Properties

Compound NameN-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide
PubChem CID161248656
Molecular FormulaC125H106F6N18O15
Molecular Weight2214.32 g/mol
Exact Mass2212.80
IUPAC NameN-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide
SMILESCn1ccc(C(=O)NCc2ccc(OCc3ccccc3F)cc2)cc1=O.Cn1cccc(C(=O)NCc2ccc(OCc3ccccc3F)cc2)c1=O.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1cc[nH]c(=O)c1.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1cccc2ncnn12.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1cccn2ncnc12.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1ccn2ncnc2c1
InChIInChI=1S/3C21H17FN4O2.2C21H19FN2O3.C20H17FN2O3/c22-19-6-2-1-4-16(19)13-28-17-9-7-15(8-10-17)12-23-21(27)18-5-3-11-26-20(18)24-14-25-26;22-18-5-2-1-4-16(18)13-28-17-10-8-15(9-11-17)12-23-21(27)19-6-3-7-20-24-14-25-26(19)20;22-19-4-2-1-3-17(19)13-28-18-7-5-15(6-8-18)12-23-21(27)16-9-10-26-20(11-16)24-14-25-26;1-24-12-4-6-18(21(24)26)20(25)23-13-15-8-10-17(11-9-15)27-14-16-5-2-3-7-19(16)22;1-24-11-10-16(12-20(24)25)21(26)23-13-15-6-8-18(9-7-15)27-14-17-4-2-3-5-19(17)22;21-18-4-2-1-3-16(18)13-26-17-7-5-14(6-8-17)12-23-20(25)15-9-10-22-19(24)11-15/h3*1-11,14H,12-13H2,(H,23,27);2-12H,13-14H2,1H3,(H,23,25);2-12H,13-14H2,1H3,(H,23,26);1-11H,12-13H2,(H,22,24)(H,23,25)
InChIKeyVAYXZMPBRDLWRZ-UHFFFAOYSA-N
XLogP19.22
TPSA397.41 Ų
H-Bond Donors7
H-Bond Acceptors26
Rotatable Bonds36
Heavy Atoms164
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002214.32
LogP ≤ 519.22
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1026

Analyze N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide with MolForge

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Related Compounds

N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2,5-dimethylpyrazole-3-carboxamide
CID 146264146
N-[[3-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;3-[3-[(2-fluorophenyl)methoxy]phenyl]-1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)propan-1-one;3-[3-[(2-fluorophenyl)methoxy]phenyl]-1-([1,2,4]triazolo[4,3-a]pyridin-6-yl)propan-1-one;3-[3-[(2-fluorophenyl)methoxy]phenyl]-1-([1,2,4]triazolo[4,3-a]pyridin-7-yl)propan-1-one
CID 167705580
N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide
CID 146264079
3-[2-fluoro-5-[(2-fluorophenyl)methoxy]phenyl]-1-(2-methylimidazo[1,2-a]pyridin-7-yl)propan-1-one;N-[[2-fluoro-5-[(2-fluorophenyl)methoxy]phenyl]methyl]-3-methylimidazo[1,2-a]pyridine-7-carboxamide;N-[[2-fluoro-5-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide
CID 167666139
N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]imidazo[1,5-a]pyridine-5-carboxamide
CID 146264115
N-[[3-[(2-fluorophenyl)methoxy]phenyl]methyl]imidazo[1,2-a]pyrazine-2-carboxamide;N-[[3-[(2-fluorophenyl)methoxy]phenyl]methyl]imidazo[1,2-a]pyridine-2-carboxamide;N-[[3-[(2-fluorophenyl)methoxy]phenyl]methyl]imidazo[1,2-a]pyrimidine-2-carboxamide;N-[[3-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide
CID 167574213
N-[[4-(4-fluorophenoxy)phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide
CID 71919015
N-[[2-fluoro-5-[(2-fluorophenyl)methoxy]phenyl]methyl]-3-methylimidazo[1,2-a]pyridine-7-carboxamide
CID 146264135
N-[(3-fluorophenyl)methyl]-1-methyl-2-oxopyridine-4-carboxamide
CID 103612084
1-methyl-2-oxo-N-[(2-phenylmethoxyphenyl)methyl]pyridine-4-carboxamide
CID 75461382
N-[(3-methoxyphenyl)methyl]-1-methyl-2-oxopyridine-4-carboxamide
CID 35676429
N-[(2-fluorophenyl)methyl]-1-methylpyrrole-2-carboxamide
CID 10889774

Frequently Asked Questions

What is the IUPAC name of N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide?
The IUPAC name of N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide (CID 161248656) is N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide.
What is the SMILES notation for N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide?
The canonical SMILES for N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide is Cn1ccc(C(=O)NCc2ccc(OCc3ccccc3F)cc2)cc1=O.Cn1cccc(C(=O)NCc2ccc(OCc3ccccc3F)cc2)c1=O.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1cc[nH]c(=O)c1.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1cccc2ncnn12.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1cccn2ncnc12.O=C(NCc1ccc(OCc2ccccc2F)cc1)c1ccn2ncnc2c1.
What is the InChIKey of N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide?
The InChIKey is VAYXZMPBRDLWRZ-UHFFFAOYSA-N. The full InChI is InChI=1S/3C21H17FN4O2.2C21H19FN2O3.C20H17FN2O3/c22-19-6-2-1-4-16(19)13-28-17-9-7-15(8-10-17)12-23-21(27)18-5-3-11-26-20(18)24-14-25-26;22-18-5-2-1-4-16(18)13-28-17-10-8-15(9-11-17)12-23-21(27)19-6-3-7-20-24-14-25-26(19)20;22-19-4-2-1-3-17(19)13-28-18-7-5-15(6-8-18)12-23-21(27)16-9-10-26-20(11-16)24-14-25-26;1-24-12-4-6-18(21(24)26)20(25)23-13-15-8-10-17(11-9-15)27-14-16-5-2-3-7-19(16)22;1-24-11-10-16(12-20(24)25)21(26)23-13-15-6-8-18(9-7-15)27-14-17-4-2-3-5-19(17)22;21-18-4-2-1-3-16(18)13-26-17-7-5-14(6-8-17)12-23-20(25)15-9-10-22-19(24)11-15/h3*1-11,14H,12-13H2,(H,23,27);2-12H,13-14H2,1H3,(H,23,25);2-12H,13-14H2,1H3,(H,23,26);1-11H,12-13H2,(H,22,24)(H,23,25).
What are the key properties of N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide?
N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide has a molecular weight of 2214.32 g/mol, XLogP of 19.22, 36 rotatable bonds, 7 hydrogen bond donors, and 26 hydrogen bond acceptors.
Where does this data come from?
All data for N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-3-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-1-methyl-2-oxopyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-2-oxo-1H-pyridine-4-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-5-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-7-carboxamide;N-[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamide is sourced from PubChem (CID 161248656), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).