5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine

C132H108Cl6N24O6 — CID 161261432

IUPAC5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine
SMILESCC(C)Oc1nc(-c2cc(Cl)c3ncccc3c2)c(-c2ccccc2)nc1N.CCOc1nc(-c2cc(Cl)c3ncccc3c2)c(-c2ccccc2)nc1N.COc1nc(-c2cc(Cl)c3ncccc3c2)c(-c2ccccc2)nc1N.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1OC1CC1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1OC1CCC1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1OC1CCCC1
InChIInChI=1S/C24H21ClN4O.C23H19ClN4O.C22H17ClN4O.C22H19ClN4O.C21H17ClN4O.C20H15ClN4O/c25-19-14-17(13-16-9-6-12-27-20(16)19)22-21(15-7-2-1-3-8-15)28-23(26)24(29-22)30-18-10-4-5-11-18;24-18-13-16(12-15-8-5-11-26-19(15)18)21-20(14-6-2-1-3-7-14)27-22(25)23(28-21)29-17-9-4-10-17;23-17-12-15(11-14-7-4-10-25-18(14)17)20-19(13-5-2-1-3-6-13)26-21(24)22(27-20)28-16-8-9-16;1-13(2)28-22-21(24)26-19(14-7-4-3-5-8-14)20(27-22)16-11-15-9-6-10-25-18(15)17(23)12-16;1-2-27-21-20(23)25-18(13-7-4-3-5-8-13)19(26-21)15-11-14-9-6-10-24-17(14)16(22)12-15;1-26-20-19(22)24-17(12-6-3-2-4-7-12)18(25-20)14-10-13-8-5-9-23-16(13)15(21)11-14/h1-3,6-9,12-14,18H,4-5,10-11H2,(H2,26,28);1-3,5-8,11-13,17H,4,9-10H2,(H2,25,27);1-7,10-12,16H,8-9H2,(H2,24,26);3-13H,1-2H3,(H2,24,26);3-12H,2H2,1H3,(H2,23,25);2-11H,1H3,(H2,22,24)
InChIKeyVCPGRIFUEZXELJ-UHFFFAOYSA-N
MW2339.20 g/mol
LogP31.55
Rot. Bonds23

About 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine

5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine (PubChem CID 161261432) has the molecular formula C132H108Cl6N24O6 and a molecular weight of 2339.20 g/mol. Its IUPAC name is 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine.

Molecular Properties

Compound Name5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine
PubChem CID161261432
Molecular FormulaC132H108Cl6N24O6
Molecular Weight2339.20 g/mol
Exact Mass2334.70
IUPAC Name5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine
SMILESCC(C)Oc1nc(-c2cc(Cl)c3ncccc3c2)c(-c2ccccc2)nc1N.CCOc1nc(-c2cc(Cl)c3ncccc3c2)c(-c2ccccc2)nc1N.COc1nc(-c2cc(Cl)c3ncccc3c2)c(-c2ccccc2)nc1N.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1OC1CC1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1OC1CCC1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1OC1CCCC1
InChIInChI=1S/C24H21ClN4O.C23H19ClN4O.C22H17ClN4O.C22H19ClN4O.C21H17ClN4O.C20H15ClN4O/c25-19-14-17(13-16-9-6-12-27-20(16)19)22-21(15-7-2-1-3-8-15)28-23(26)24(29-22)30-18-10-4-5-11-18;24-18-13-16(12-15-8-5-11-26-19(15)18)21-20(14-6-2-1-3-7-14)27-22(25)23(28-21)29-17-9-4-10-17;23-17-12-15(11-14-7-4-10-25-18(14)17)20-19(13-5-2-1-3-6-13)26-21(24)22(27-20)28-16-8-9-16;1-13(2)28-22-21(24)26-19(14-7-4-3-5-8-14)20(27-22)16-11-15-9-6-10-25-18(15)17(23)12-16;1-2-27-21-20(23)25-18(13-7-4-3-5-8-13)19(26-21)15-11-14-9-6-10-24-17(14)16(22)12-15;1-26-20-19(22)24-17(12-6-3-2-4-7-12)18(25-20)14-10-13-8-5-9-23-16(13)15(21)11-14/h1-3,6-9,12-14,18H,4-5,10-11H2,(H2,26,28);1-3,5-8,11-13,17H,4,9-10H2,(H2,25,27);1-7,10-12,16H,8-9H2,(H2,24,26);3-13H,1-2H3,(H2,24,26);3-12H,2H2,1H3,(H2,23,25);2-11H,1H3,(H2,22,24)
InChIKeyVCPGRIFUEZXELJ-UHFFFAOYSA-N
XLogP31.55
TPSA443.52 Ų
H-Bond Donors6
H-Bond Acceptors30
Rotatable Bonds23
Heavy Atoms168
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002339.20
LogP ≤ 531.55
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1030

Analyze 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine with MolForge

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Frequently Asked Questions

What is the IUPAC name of 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine?
The IUPAC name of 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine (CID 161261432) is 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine.
What is the SMILES notation for 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine?
The canonical SMILES for 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine is CC(C)Oc1nc(-c2cc(Cl)c3ncccc3c2)c(-c2ccccc2)nc1N.CCOc1nc(-c2cc(Cl)c3ncccc3c2)c(-c2ccccc2)nc1N.COc1nc(-c2cc(Cl)c3ncccc3c2)c(-c2ccccc2)nc1N.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1OC1CC1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1OC1CCC1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1OC1CCCC1.
What is the InChIKey of 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine?
The InChIKey is VCPGRIFUEZXELJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H21ClN4O.C23H19ClN4O.C22H17ClN4O.C22H19ClN4O.C21H17ClN4O.C20H15ClN4O/c25-19-14-17(13-16-9-6-12-27-20(16)19)22-21(15-7-2-1-3-8-15)28-23(26)24(29-22)30-18-10-4-5-11-18;24-18-13-16(12-15-8-5-11-26-19(15)18)21-20(14-6-2-1-3-7-14)27-22(25)23(28-21)29-17-9-4-10-17;23-17-12-15(11-14-7-4-10-25-18(14)17)20-19(13-5-2-1-3-6-13)26-21(24)22(27-20)28-16-8-9-16;1-13(2)28-22-21(24)26-19(14-7-4-3-5-8-14)20(27-22)16-11-15-9-6-10-25-18(15)17(23)12-16;1-2-27-21-20(23)25-18(13-7-4-3-5-8-13)19(26-21)15-11-14-9-6-10-24-17(14)16(22)12-15;1-26-20-19(22)24-17(12-6-3-2-4-7-12)18(25-20)14-10-13-8-5-9-23-16(13)15(21)11-14/h1-3,6-9,12-14,18H,4-5,10-11H2,(H2,26,28);1-3,5-8,11-13,17H,4,9-10H2,(H2,25,27);1-7,10-12,16H,8-9H2,(H2,24,26);3-13H,1-2H3,(H2,24,26);3-12H,2H2,1H3,(H2,23,25);2-11H,1H3,(H2,22,24).
What are the key properties of 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine?
5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine has a molecular weight of 2339.20 g/mol, XLogP of 31.55, 23 rotatable bonds, 6 hydrogen bond donors, and 30 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(8-chloroquinolin-6-yl)-3-cyclobutyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopentyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-cyclopropyloxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-ethoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-3-methoxy-6-phenylpyrazin-2-amine;5-(8-chloroquinolin-6-yl)-6-phenyl-3-propan-2-yloxypyrazin-2-amine is sourced from PubChem (CID 161261432), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).