N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide

C96H88F12N16O12 — CID 161269188

IUPACN-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
SMILESCn1cc(-c2cc(NC(=O)c3cccc(C(F)F)c3)ccc2F)cc(N2CCOCC2)c1=O.Cn1cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)ccc2C#N)cc(N2CCOCC2)c1=O.Cn1cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)ccc2F)cc(N2CCOCC2)c1=O.Cn1cc(-c2cc(NC(=O)c3ccnc(C(F)(F)F)c3)ccc2F)cc(N2CCOCC2)c1=O
InChIInChI=1S/C25H23F2N5O3.C24H23F3N4O3.C24H22F3N3O3.C23H20F4N4O3/c1-25(26,27)22-12-16(5-6-29-22)23(33)30-19-4-3-17(14-28)20(13-19)18-11-21(24(34)31(2)15-18)32-7-9-35-10-8-32;1-24(26,27)21-12-15(5-6-28-21)22(32)29-17-3-4-19(25)18(13-17)16-11-20(23(33)30(2)14-16)31-7-9-34-10-8-31;1-29-14-17(12-21(24(29)32)30-7-9-33-10-8-30)19-13-18(5-6-20(19)25)28-23(31)16-4-2-3-15(11-16)22(26)27;1-30-13-15(10-19(22(30)33)31-6-8-34-9-7-31)17-12-16(2-3-18(17)24)29-21(32)14-4-5-28-20(11-14)23(25,26)27/h3-6,11-13,15H,7-10H2,1-2H3,(H,30,33);3-6,11-14H,7-10H2,1-2H3,(H,29,32);2-6,11-14,22H,7-10H2,1H3,(H,28,31);2-5,10-13H,6-9H2,1H3,(H,29,32)
InChIKeyVDOWHYVJOYRDRC-UHFFFAOYSA-N
MW1885.84 g/mol
LogP15.22
Rot. Bonds19

About N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide

N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide (PubChem CID 161269188) has the molecular formula C96H88F12N16O12 and a molecular weight of 1885.84 g/mol. Its IUPAC name is N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide.

Molecular Properties

Compound NameN-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
PubChem CID161269188
Molecular FormulaC96H88F12N16O12
Molecular Weight1885.84 g/mol
Exact Mass1884.66
IUPAC NameN-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
SMILESCn1cc(-c2cc(NC(=O)c3cccc(C(F)F)c3)ccc2F)cc(N2CCOCC2)c1=O.Cn1cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)ccc2C#N)cc(N2CCOCC2)c1=O.Cn1cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)ccc2F)cc(N2CCOCC2)c1=O.Cn1cc(-c2cc(NC(=O)c3ccnc(C(F)(F)F)c3)ccc2F)cc(N2CCOCC2)c1=O
InChIInChI=1S/C25H23F2N5O3.C24H23F3N4O3.C24H22F3N3O3.C23H20F4N4O3/c1-25(26,27)22-12-16(5-6-29-22)23(33)30-19-4-3-17(14-28)20(13-19)18-11-21(24(34)31(2)15-18)32-7-9-35-10-8-32;1-24(26,27)21-12-15(5-6-28-21)22(32)29-17-3-4-19(25)18(13-17)16-11-20(23(33)30(2)14-16)31-7-9-34-10-8-31;1-29-14-17(12-21(24(29)32)30-7-9-33-10-8-30)19-13-18(5-6-20(19)25)28-23(31)16-4-2-3-15(11-16)22(26)27;1-30-13-15(10-19(22(30)33)31-6-8-34-9-7-31)17-12-16(2-3-18(17)24)29-21(32)14-4-5-28-20(11-14)23(25,26)27/h3-6,11-13,15H,7-10H2,1-2H3,(H,30,33);3-6,11-14H,7-10H2,1-2H3,(H,29,32);2-6,11-14,22H,7-10H2,1H3,(H,28,31);2-5,10-13H,6-9H2,1H3,(H,29,32)
InChIKeyVDOWHYVJOYRDRC-UHFFFAOYSA-N
XLogP15.22
TPSA316.74 Ų
H-Bond Donors4
H-Bond Acceptors24
Rotatable Bonds19
Heavy Atoms136
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001885.84
LogP ≤ 515.22
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1024

Analyze N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

2-(1,1-difluoropropyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridin-3-yl)phenyl]pyridine-4-carboxamide
CID 90461377
N-[3-[1-(2-cyanoethyl)-5-morpholin-4-yl-6-oxopyridin-3-yl]-4-methylphenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide
CID 90462243
US11377431, Example 38
CID 163255657
N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxopyridin-3-yl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide
CID 90462642
US11377431, Example 39
CID 163255634
N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxopyridin-3-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 90462968
US11459339, Example 9
CID 139375270
N-[3-[7-(3-aminopropyl)-1-(2-morpholin-4-ylethyl)-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-morpholin-4-yl-5-(trifluoromethyl)benzamide
CID 24953826
N-[3-[7-(3-aminopropyl)-1-(2-morpholin-4-ylethyl)-2-oxo-1,6-naphthyridin-3-yl]-2-fluoro-4-methylphenyl]-3-(trifluoromethyl)benzamide
CID 24955259
N-[5-[7-(3-aminopropyl)-1-(2-morpholin-4-ylethyl)-2-oxo-1,6-naphthyridin-3-yl]-2-fluoro-4-methylphenyl]-3-(trifluoromethyl)benzamide
CID 24955260
N-[3-[7-(3-aminopropyl)-1-(2-morpholin-4-ylethyl)-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzamide
CID 24955262
3-(4-acetamidopiperidin-1-yl)-N-[4-methyl-3-[7-methyl-1-(2-morpholin-4-ylethyl)-2-oxo-1,6-naphthyridin-3-yl]phenyl]-5-(trifluoromethyl)benzamide
CID 59212490

Frequently Asked Questions

What is the IUPAC name of N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The IUPAC name of N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide (CID 161269188) is N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide.
What is the SMILES notation for N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The canonical SMILES for N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide is Cn1cc(-c2cc(NC(=O)c3cccc(C(F)F)c3)ccc2F)cc(N2CCOCC2)c1=O.Cn1cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)ccc2C#N)cc(N2CCOCC2)c1=O.Cn1cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)ccc2F)cc(N2CCOCC2)c1=O.Cn1cc(-c2cc(NC(=O)c3ccnc(C(F)(F)F)c3)ccc2F)cc(N2CCOCC2)c1=O.
What is the InChIKey of N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The InChIKey is VDOWHYVJOYRDRC-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H23F2N5O3.C24H23F3N4O3.C24H22F3N3O3.C23H20F4N4O3/c1-25(26,27)22-12-16(5-6-29-22)23(33)30-19-4-3-17(14-28)20(13-19)18-11-21(24(34)31(2)15-18)32-7-9-35-10-8-32;1-24(26,27)21-12-15(5-6-28-21)22(32)29-17-3-4-19(25)18(13-17)16-11-20(23(33)30(2)14-16)31-7-9-34-10-8-31;1-29-14-17(12-21(24(29)32)30-7-9-33-10-8-30)19-13-18(5-6-20(19)25)28-23(31)16-4-2-3-15(11-16)22(26)27;1-30-13-15(10-19(22(30)33)31-6-8-34-9-7-31)17-12-16(2-3-18(17)24)29-21(32)14-4-5-28-20(11-14)23(25,26)27/h3-6,11-13,15H,7-10H2,1-2H3,(H,30,33);3-6,11-14H,7-10H2,1-2H3,(H,29,32);2-6,11-14,22H,7-10H2,1H3,(H,28,31);2-5,10-13H,6-9H2,1H3,(H,29,32).
What are the key properties of N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?
N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide has a molecular weight of 1885.84 g/mol, XLogP of 15.22, 19 rotatable bonds, 4 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-cyano-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]benzamide;N-[4-fluoro-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide is sourced from PubChem (CID 161269188), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).